Diabetes, 1939-327X

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  1. Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

    Abderrahmani, A., Yengo, L., Caiazzo, R., Canouil, M., Cauchi, S., Raverdy, V., Plaisance, V., Pawlowski, V., Lobbens, S., Maillet, J., Rolland, L., Boutry, R., Queniat, G., Kwapich, M., Tenenbaum, M., Bricambert, J., Saussenthaler, S., Anthony, E., Jha, P., Derop, J. & 18 othersSand, O., Rabearivelo, I., Leloire, A., Pigeyre, M., Daujat-Chavanieu, M., Gerbal-Chaloin, S., Dayeh, T., Lassailly, G., Mathurin, P., Staels, B., Auwerx, J., Schürmann, A., Postic, C., Schafmayer, C., Hampe, J., Bonnefond, A., Pattou, F. & Froguel, P., 2018 Jul 1, In : Diabetes. 67, 7, p. 1310-1321 12 p.

    Research output: Contribution to journalArticle

  2. GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

    af Hällström-Reijonen, C., Daniels, T. L., A. Lernmark & Nepom, G. T., 2000, In : Diabetes. 49, 10, p. 1621-1626 6 p.

    Research output: Contribution to journalArticle

  3. The effect of pronounced hypoglycemia on monoamine metabolism in rat brain

    Agardh, C-D., Carlsson, A., Linqvist, M. & Siesjö, B., 1979, In : Diabetes. 28, 9, p. 804-809

    Research output: Contribution to journalArticle

  4. A link between GIP and osteopontin in adipose tissue and insulin resistance.

    Ahlqvist, E., Osmark, P., Kuulasmaa, T., Pilgaard, K., Omar, B., Brøns, C., Kotova, O., Zetterqvist, A., Stancáková, A., Jonsson, A., Hansson, O., Kuusisto, J., Kieffer, T. J., Tuomi, T., Isomaa, B., Madsbad, S., Gomez, M. F., Poulsen, P., Laakso, M., Degerman, E. & 5 othersPihlajamäki, J., Nils Wierup, Allan Vaag, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 6, p. 2088-2094

    Research output: Contribution to journalArticle

  5. Hepato-Incretin Function of GLP-1: Novel Concept and Target in Type 1 Diabetes.

    Bo Ahrén, 2015, In : Diabetes. 64, 3, p. 715-717

    Research output: Contribution to journalDebate/Note/Editorial

  6. Neuropeptides and the regulation of islet function.

    Bo Ahrén, Nils Wierup & Sundler, F., 2006, In : Diabetes. 55, Suppl 2, p. S98-S107

    Research output: Contribution to journalArticle

  7. Quantification of insulin secretion in relation to insulin sensitivity in nondiabetic postmenopausal women.

    Bo Ahrén & Larsson, H., 2002, In : Diabetes. 51, Suppl 1, p. S202-S211

    Research output: Contribution to journalArticle

  8. Metabolite profiling of LADA challenges the view of a metabolically distinct subtype

    Al-Majdoub, M., Ali, A., Storm, P., Anders H. Rosengren, Leif Groop & Peter Spégel, 2017 Apr 1, In : Diabetes. 66, 4, p. 806-814 9 p.

    Research output: Contribution to journalArticle

  9. Antidiabetic Actions of an Estrogen Receptor beta Selective Agonist

    Alonso-Magdalena, P., Ropero, A. B., Garcia-Arevalo, M., Soriano, S., Quesada, I., Jabar Muhammed, S., S Albert Salehi, Gustafsson, J-A. & Nadal, A., 2013, In : Diabetes. 62, 6, p. 2015-2025

    Research output: Contribution to journalArticle

  10. Glutamine-elicited secretion of glucagon-like peptide 1 is governed by an activated glutamate dehydrogenase

    Andersson, L. E., Shcherbina, L., Al-Majdoub, M., Neelanjan Vishnu, Arroyo, C. B., Carrara, J. A., Claes B. Wollheim, Malin Fex, Hindrik Mulder, Nils Wierup & Peter Spégel, 2018 Mar 1, In : Diabetes. 67, 3, p. 372-384 13 p.

    Research output: Contribution to journalArticle

  11. MafA and MafB Regulate Genes Critical to beta-Cells in a Unique Temporal Manner

    Isabella Artner, Hang, Y., Mazur, M., Yamamoto, T., Guo, M., Lindner, J., Magnuson, M. A. & Stein, R., 2010, In : Diabetes. 59, 10, p. 2530-2539

    Research output: Contribution to journalArticle

  12. Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells

    Barg, S., Galvanovskis, J., Gopel, S. O., Rorsman, P. & Lena Eliasson, 2000, In : Diabetes. 49, 9, p. 1500-1510

    Research output: Contribution to journalArticle

  13. Hepatic DPP4 DNA methylation associates with fatty liver

    Baumeier, C., Saussenthaler, S., Kammel, A., Jähnert, M., Schlüter, L., Hesse, D., Canouil, M., Lobbens, S., Caiazzo, R., Raverdy, V., Pattou, F., Nilsson, E., Pihlajamäki, J., Charlotte Ling, Froguel, P., Schürmann, A. & Schwenk, R. W., 2017 Jan 1, In : Diabetes. 66, 1, p. 25-35 11 p.

    Research output: Contribution to journalArticle

  14. Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

    Berglund, L., Lyssenko, V., Ladenvall, C., Kotova, O., Edsfeldt, A., Pilgaard, K., Alkayyali, S., Brøns, C., Forsblom, C., Jonsson, A., Zetterqvist, A., Nitulescu, M., Ruiz McDavitt, C., Dunér, P., Stancáková, A., Kuusisto, J., Ahlqvist, E., Lajer, M., Tarnow, L., Madsbad, S. & 13 othersRossing, P., Kieffer, T. J., Olle Melander, Marju Orho-Melander, Peter Nilsson, Groop, P-H., Allan Vaag, Lindblad, B., Anders Gottsäter, Laakso, M., Isabel Goncalves, Leif Groop & Maria Gomez, 2016, In : Diabetes. 65, 1, p. 239-254

    Research output: Contribution to journalArticle

  15. Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia

    Bohlooly, M., Olsson, B., Bruder, CEG., Linden, D., Sjogren, K., Bjursell, M., Egecioglu, E., Svensson, L., Brodin, P., Waterton, JC., Isaksson, OGP., Sundler, F., Bo Ahrén, Ohlsson, C., Oscarsson, J. & Tornell, J., 2005, In : Diabetes. 54, 1, p. 51-62

    Research output: Contribution to journalArticle

  16. Association of IDDM and attenuated response of 2',5'-oligoadenylate synthetase to yellow fever vaccine

    Bonnevie-Nielsen, V., Larsen, M. L., Frifelt, J. J., Michelsen, B. & A. Lernmark, 1989 Jan 1, In : Diabetes. 38, 12, p. 1636-1642

    Research output: Contribution to journalArticle

  17. An H-2 alloantiserum preserves β-cell function in mice made diabetic by low-dose streptozotocin

    Bonnevie-Nielsen, V. & A. Lernmark, 1986 Jan 1, In : Diabetes. 35, 5, p. 570-573 4 p.

    Research output: Contribution to journalArticle

  18. A major loss in islet mass and b-cell function precedes hyperglycemia in mice given multiple low doses of streptozotocin

    Bonnevie-Nielsen, V., Steffes, M. W. & A. Lernmark, 1981 Jan 1, In : Diabetes. 30, 5, p. 424-429

    Research output: Contribution to journalArticle

  19. A 12-year prospective study of the relationship between islet antibodies and beta-cell function at and after the diagnosis in patients with adult-onset diabetes.

    Borg, H., Anders Gottsäter, Fernlund, P. & Sundkvist, G., 2002, In : Diabetes. 51, 6, p. 1754-1762

    Research output: Contribution to journalArticle

  20. The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes

    Bostrom, P., Andersson, L., Vind, B., Haversen, L., Rutberg, M., Wickstrom, Y., Larsson, E., Jansson, P-A., Svensson, M. K., Branemark, R., Charlotte Ling, Beck-Nielsen, H., Boren, J., Hojlund, K. & Olofsson, S-O., 2010, In : Diabetes. 59, 8, p. 1870-1878

    Research output: Contribution to journalArticle

  21. Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing {beta}-Cell-Like Cells.

    Brolén, G., Heins, N., Edsbagge, J. & Semb, H., 2005, In : Diabetes. 54, 10, p. 2867-2874

    Research output: Contribution to journalArticle

  22. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

    Cabric, S., Sanchez, J., Lundgren, T., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibell, A., Tufveson, G., Larsson, R., Korsgren, O. & Nilsson, B., 2007, In : Diabetes. 56, 8, p. 2008-2015

    Research output: Contribution to journalArticle

  23. Association studies of BMI and type 2 diabetes in the neuropeptide y pathway - A possible role for NPY2R as a candidate gene for type 2 diabetes in men

    Campbell, C. D., Lyon, H. N., Nemesh, J., Drake, J. A., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R. S., Ardlie, K. G., Leif Groop & Hirschhorn, J. N., 2007, In : Diabetes. 56, 5, p. 1460-1467

    Research output: Contribution to journalArticle

  24. Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes

    Cervin, C., Valeriya Lyssenko, Bakhtadze, E., Eero Lindholm, Peter Nilsson, Tuomi, T., Corrado Cilio & Leif Groop, 2008, In : Diabetes. 57, 5, p. 1433-1437

    Research output: Contribution to journalArticle

  25. Cosegregation of MIDD and MODY in a Pedigree: Functional and Clinical Consequences.

    Cervin, C., Liljeström, B., Tuomi, T., Heikkinen, S., Tapanainen, J. S., Leif Groop & Corrado Cilio, 2004, In : Diabetes. 53, 7, p. 1894-1899

    Research output: Contribution to journalArticle

  26. Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion

    Collins, S. C., Do, H. W., Hastoy, B., Hugill, A., Adam, J., Chibalina, M. V., Galvanovskis, J., Godazgar, M., Lee, S., Goldsworthy, M., S Albert Salehi, Tarasov, A. I., Anders H. Rosengren, Cox, R. & Rorsman, P., 2016 Jul 1, In : Diabetes. 65, 7, p. 1952-1961 10 p.

    Research output: Contribution to journalArticle

  27. Type 1 Diabetes: Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

    Concannon, P., Erlich, HA., Julier, C., Morahan, G., Nerup, J., Pociot, F., Todd, JA., Rich, SS., Type 1 Diabetes Genetics Consortium, T. & Joyce Carlson, 2005, In : Diabetes. 54, p. 2995-3001

    Research output: Contribution to journalArticle

  28. Aged Transgenic Mice With Increased Glucocorticoid Sensitivity in Pancreatic beta-Cells Develop Diabetes.

    Davani, B., Portwood, N., Bryzgalova, G., Reimer, M. K., Heiden, T., Ostenson, C-G., Okret, S., Bo Ahrén, Efendic, S. & Khan, A., 2004, In : Diabetes. 53, Suppl 1, p. S51-S59

    Research output: Contribution to journalArticle

  29. Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.

    Dekker Nitert, M., Dayeh, T., Volkov, P., Elgzyri, T., Hall, E., Nilsson, E., Yang, B., Lang, S., Parikh, H., Wessman, Y., Weishaupt, H., Attema, J., Abels, M., Wierup, N., Almgren, P., Jansson, P-A., Rönn, T., Hansson, O., Eriksson, K-F., Groop, L. & 1 othersCharlotte Ling, 2012, In : Diabetes.

    Research output: Contribution to journalArticle

  30. Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study.

    Delli, A., Vaziri Sani, F., Lindblad, B., Helena Larsson, Annelie Carlsson, Forsander, G., Sten Ivarsson, Ludvigsson, J., Kockum, I., Marcus, C., Samuelsson, U., Ortqvist, E., Leif Groop, Bondinas, G. P., Papadopoulos, G. K. & Åke Lernmark, 2012, In : Diabetes. 61, 10, p. 2556-2564

    Research output: Contribution to journalArticle

  31. Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism

    Ding, W. G., Erik Renström, Rorsman, P., Buschard, K. & Gromada, J., 1997, In : Diabetes. 46, 5, p. 792-800

    Research output: Contribution to journalArticle

  32. The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human.

    E, K., N, K., R, K., J, W., CM, O., E, W., Dan Holmberg, S, C. & L, S., 2013, In : Diabetes. 62, 2, p. 531-542

    Research output: Contribution to journalArticle

  33. A unique defect in the regulation of visceral fat cell lipolysis in the polycystic ovary syndrome as an early link to insulin resistance

    Ek, I., Arner, P., Ryden, M., Cecilia Holm, Thorne, A., Hoffstedt, J. & Wahrenberg, H., 2002, In : Diabetes. 51, 2, p. 484-492

    Research output: Contribution to journalArticle

  34. 5 ' flanking variants of resistin are associated with obesity

    Engert, JC., Vohl, MC., Williams, SM., Lepage, P., Loredo-Osti, JC., Faith, J., Dore, C., Renaud, Y., Burtt, NP., Villeneuve, A., Hirschhorn, JN., Altshuler, D., Leif Groop, Despres, JP., Gaudet, D. & Hudson, TJ., 2002, In : Diabetes. 51, 5, p. 1629-1634

    Research output: Contribution to journalArticle

  35. Inflammation-sensitive plasma proteins are associated with future weight gain.

    Gunnar Engström, Bo Hedblad, Stavenow, L., Lind, P., Janzon, L. & Lindgärde, F., 2003, In : Diabetes. 52, 8, p. 2097-2101

    Research output: Contribution to journalArticle

  36. Complement c3 is a risk factor for the development of diabetes: a population-based cohort study.

    Gunnar Engström, Bo Hedblad, Karl-Fredrik Eriksson, Janzon, L. & Lindgärde, F., 2005, In : Diabetes. 54, 2, p. 570-575

    Research output: Contribution to journalArticle

  37. Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: a population-based study.

    Gunnar Engström, Stavenow, L., Bo Hedblad, Lind, P., Karl-Fredrik Eriksson, Janzon, L. & Lindgärde, F., 2003, In : Diabetes. 52, 2, p. 442-447

    Research output: Contribution to journalArticle

  38. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the Type 1 Diabetes Genetics Consortium families

    Erlich, H., Valdes, A. M., Noble, J., Joyce Carlson, Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., Lavant, E., Louey, A. & Moonsamy, P., 2008, In : Diabetes. 57, 4, p. 1084-1092

    Research output: Contribution to journalArticle

  39. Insulin resistance is accompanied by increased fasting glucagon and delayed glucagon suppression in individuals with normal and impaired glucose regulation

    Færch, K., Vistisen, D., Pacini, G., Torekov, S. S., Johansen, N. B., Witte, D. R., Jonsson, A., Pedersen, O., Hansen, T., Lauritzen, T., Jørgensen, M. E., Bo Ahrén & Holst, J. J., 2016 Nov 1, In : Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journalArticle

  40. Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.

    Fall, T., Hägg, S., Ploner, A., Mägi, R., Fischer, K., Draisma, H. H. M., Sarin, A-P., Benyamin, B., Ladenvall, C., Åkerlund, M., Kals, M., Esko, T., Nelson, C. P., Kaakinen, M., Huikari, V., Mangino, M., Meirhaeghe, A., Kristiansson, K., Nuotio, M-L., Kobl, M. & 68 othersGrallert, H., Dehghan, A., Kuningas, M., de Vries, P. S., de Bruijn, R. F. A. G., Willems, S. M., Heikkilä, K., Silventoinen, K., Pietiläinen, K. H., Legry, V., Giedraitis, V., Goumidi, L., Syvänen, A-C., Strauch, K., Koenig, W., Lichtner, P., Herder, C., Palotie, A., Menni, C., Uitterlinden, A. G., Kuulasmaa, K., Havulinna, A. S., Moreno, L. A., Gonzalez-Gross, M., Evans, A., Tregouet, D-A., Yarnell, J. W. G., Virtamo, J., Ferrières, J., Veronesi, G., Perola, M., Arveiler, D., Brambilla, P., Lind, L., Kaprio, J., Hofman, A., Stricker, B. H., van Duijn, C. M., Ikram, M. A., Franco, O. H., Cottel, D., Dallongeville, J., Hall, A. S., Jula, A., Tobin, M. D., Penninx, B. W., Peters, A., Gieger, C., Samani, N. J., Montgomery, G. W., Whitfield, J. B., Martin, N. G., Leif Groop, Spector, T. D., Magnusson, P. K., Amouyel, P., Boomsma, D. I., Peter Nilsson, Järvelin, M-R., Valeriya Lyssenko, Metspalu, A., Strachan, D. P., Salomaa, V., Ripatti, S., Pedersen, N. L., Prokopenko, I., McCarthy, M. I. & Ingelsson, E., 2015, In : Diabetes. 64, 5, p. 1841-1852

    Research output: Contribution to journalArticle

  41. Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes.

    Fall, T., Xie, W., Poon, W., Yaghootkar, H., Mägi, R., Knowles, J. W., Valeriya Lyssenko, Weedon, M., Frayling, T. M. & Ingelsson, E., 2015, In : Diabetes. 64, 7, p. 2676-2684

    Research output: Contribution to journalArticle

  42. Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance

    Ferrannini, E., Natali, A., Camastra, S., Nannipieri, M., Mari, A., Adam, K-P., Milburn, M. V., Kastemmueller, G., Adamski, J., Tuomi, T., Valeriya Lyssenko, Leif Groop & Gall, W. E., 2013, In : Diabetes. 62, 5, p. 1730-1737

    Research output: Contribution to journalArticle

  43. {beta}-Cell Lipases and Insulin Secretion.

    Malin Fex, Lucas, S., Sörhede Winzell, M., Bo Ahrén, Cecilia Holm & Hindrik Mulder, 2006, In : Diabetes. 55, Suppl 2, p. S24-S31

    Research output: Contribution to journalArticle

  44. A global overview of precision medicine in type 2 diabetes

    Hugo Fitipaldi, McCarthy, M. I., Florez, J. C. & Paul W. Franks, 2018, In : Diabetes. 67, 10, p. 1911-1922 12 p.

    Research output: Contribution to journalReview article

  45. Activation of enteroendocrine membrane progesterone receptors promotes incretin secretion and improves glucose tolerance in mice

    Flock, G. B., Cao, X., Marlena Maziarz & Drucker, D. J., 2013 Jan 1, In : Diabetes. 62, 1, p. 283-290 8 p.

    Research output: Contribution to journalArticle

  46. High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

    Florez, JC., Wiltshire, S., Agapakis, CM., Burtt, NP., de Bakker, PIW., Almgren, P., Bostrom, KB., Tuomi, T., Gaudet, D., Daly, MJ., Hirschhorn, JN., McCarthy, MI., Altshuler, D. & Leif Groop, 2006, In : Diabetes. 55, 1, p. 128-135

    Research output: Contribution to journalArticle

  47. Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people

    Florez, J. C., Agapakis, C. M., Burtt, N. P., Sun, M., Almgren, P., Lennart Råstam, Tuomi, T., Gaudet, D., Hudson, T. J., Daly, M. J., Ardlie, K. G., Hirschhorn, J. N., Leif Groop & Altshuler, B., 2005, In : Diabetes. 54, 6, p. 1884-1891

    Research output: Contribution to journalArticle

  48. Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region.

    Florez, J. C., Burtt, N., De Bakker, P. I. W., Almgren, P., Tuomi, T., Holmkvist, J., Gaudet, D., Hudson, T. J., Schaffner, S. F., Daly, M. J., Hirschhorn, J. N., Leif Groop & Altshuler, D., 2004, In : Diabetes. 53, 5, p. 1360-1368

    Research output: Contribution to journalArticle

  49. The Kruppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people

    Florez, J. C., Saxena, R., Winckler, W., Burtt, N. P., Almgren, P., Kristina Bengtsson Boström, Tuomi, T., Gaudet, D., Ardlie, K. G., Daly, M. J., Altshuler, D., Hirschhorn, J. N. & Leif Groop, 2006, In : Diabetes. 55, 12, p. 3620-3624

    Research output: Contribution to journalArticle

  50. Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes

    Florez, JC., Marketa Sjögren, Burtt, N., Marju Orho-Melander, Schayer, S., Sun, M., Almgren, P., Lindblad, U., Tuomi, T., Gaudet, D., Hudson, TJ., Daly, MJ., Ardlie, KG., Hirschhorn, JN., Altshuler, D. & Leif Groop, 2004, In : Diabetes. 53, 12, p. 3313-3318

    Research output: Contribution to journalArticle

  51. Diabetes family history: a metabolic storm you should not sit out.

    Paul Franks, 2010, In : Diabetes. 59, p. 2732-2734

    Research output: Contribution to journalArticle

  52. Using genotype-based recall to estimate the effects of amy1 copy number variation in substrate metabolism

    Paul W. Franks & Frida Renström, 2016 Nov 1, In : Diabetes. 65, 11, p. 3240-3242 3 p.

    Research output: Contribution to journalDebate/Note/Editorial

  53. A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity.

    Frayling, T. M., Lindgren, C., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A. & 9 othersCognet, I., Hansen, T., Pedersen, O., Ellard, S., Tuomi, T., Leif Groop, Froguel, P., Hattersley, A. T. & Vaxillaire, M., 2003, In : Diabetes. 52, 3, p. 872-881

    Research output: Contribution to journalArticle

  54. Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.

    Fuller, J., Kwitek, A. E., Hawkins, T. J., Moralejo, D. H., Lu, W., Tupling, T. D., Macmurray, A. J., Borchardt, G., Hasinoff, M. & Åke Lernmark, 2006, In : Diabetes. 55, p. 3351-3357

    Research output: Contribution to journalArticle

  55. Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression

    Galgani, M., Nugnes, R., Bruzzese, D., Perna, F., De Rosa, V., Procaccini, C., Mozzillo, E., Corrado Cilio, Helena Larsson, Åke Lernmark, La Cava, A., Franzese, A. & Matarese, G., 2013, In : Diabetes. 62, 7, p. 2481-2491

    Research output: Contribution to journalArticle

  56. Mature-onset obesity in interleukin-1 receptor I knockout mice

    Garcia, MC., Wernstedt, I., Berndtsson, A., Enge, M., Bell, M., Hultgren, O., Horn, M., Bo Ahrén, Enerback, S., Ohlsson, C., Wallenius, V. & Jansson, JO., 2006, In : Diabetes. 55, 5, p. 1205-1213

    Research output: Contribution to journalArticle

  57. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes.

    Graham, J., Hagopian, WA., Kockum, I., Li, LS., Sanjeevi, CB., Lowe, RM., Schaefer, JB., Zarghami, M., Day, HL., Mona Landin-Olsson, Palmer, JP., Janer-Villanueva, M., Hood, L., Sundkvist, G., Åke Lernmark, Breslow, N., Dahlquist, G. & Blohme, G., 2002, In : Diabetes. 51, 5, p. 1346-1355

    Research output: Contribution to journalArticle

  58. Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop

    Greenbaum, C. J., Palmer, J. P., Nagataki, S., Yamaguchi, Y., Molenaar, J. L., Van Beers, W. A. M., Maclaren, N. K., A. Lernmark, Villena, A. A., Barbosa, J., DeBeaufort, C., Becker, D., Becker, F., Betterle, C., Bosi, E., Bottazzo, G. F., Bright, G., Colman, P. & Dawkins, R. L., 1992 Jan 1, In : Diabetes. 41, 12, p. 1570-1574

    Research output: Contribution to journalArticle

  59. Metabolic and underlying causes of diabetes mellitus

    Grodsky, G. M., Anderson, C. E., Coleman, D. L., Craighead, J. E., Gerritsen, G. C., Hansen, C. T., Herberg, L., Howard, C. F., A. Lernmark, Matschinsky, F. M., Rayfield, E., Riley, W. J. & Rossini, A. A., 1982 Dec 4, In : Diabetes. 31, Suppl. 1, p. 45-53 9 p.

    Research output: Contribution to journalArticle

  60. Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization

    Gromada, J., Dissing, S., Bokvist, K., Erik Renström, Frokjaer-Jensen, J., Wulff, B. S. & Rorsman, P., 1995, In : Diabetes. 44, 7, p. 767-774

    Research output: Contribution to journalArticle

  61. Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

    Grunnet, L. G., Nilsson, E., Charlotte Ling, Hansen, T., Pedersen, O., Leif Groop, Vaag, A. & Poulsen, P., 2009, In : Diabetes. 58, 10, p. 2402-2408

    Research output: Contribution to journalArticle

  62. Autoantibodies in IDDM primarily recognize the 65,000-Mr rather than the 67,000-Mr isoform of glutamic acid decarboxylase

    Hagopian, W. A., Michelsen, B., Karlsen, A. E., Larsen, F., Moody, A., Grubin, C. E., Rowe, R., Petersen, J., Mcevoy, R. & Åke Lernmark, 1993 Jan 1, In : Diabetes. 42, 4, p. 631-636

    Research output: Contribution to journalArticle

  63. Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: How High Must the Standards Be Set?

    Halban, P. A., Kahn, S. E., Åke Lernmark & Rhodes, C. J., 2001 Oct, In : Diabetes. 50, 10, p. 2181-2191 11 p.

    Research output: Contribution to journalReview article

  64. Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells

    Alexander Hamilton, Zhang, Q., Albert Salehi, Willems, M., Knudsen, J. G., Ringgaard, A. K., Chapman, C. E., Gonzalez-Alvarez, A., Surdo, N. C., Zaccolo, M., Basco, D., Johnson, P. R. V., Ramracheya, R., Rutter, G. A., Galione, A., Rorsman, P. & Tarasov, A. I., 2018 Jun, In : Diabetes. 67, 6, p. 1128-1139 12 p.

    Research output: Contribution to journalArticle

  65. In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse - Pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

    Henquin, JC., Nenquin, M., Stiernet, P. & Bo Ahrén, 2006, In : Diabetes. 55, 2, p. 441-451

    Research output: Contribution to journalArticle

  66. FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

    Hertel, J. K., Johansson, S., Emily Sonestedt, Jonsson, A., Lie, R. T., Platou, C. G. P., Peter Nilsson, Rukh, G., Midthjell, K., Hveem, K., Olle Melander, Leif Groop, Valeriya Lyssenko, Molven, A., Marju Orho-Melander & Njolstad, P. R., 2011, In : Diabetes. 60, 5, p. 1637-1644

    Research output: Contribution to journalArticle

  67. Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.

    Hivert, M-F., Christophi, C. A., Paul Franks, Jablonski, K. A., Ehrmann, D. A., Kahn, S. E., Horton, E. S., Pollin, T. I., Mather, K. J., Perreault, L., Barrett-Connor, E., Knowler, W. C. & Florez, J. C., 2016 Feb, In : Diabetes. 65, 2, p. 520-526

    Research output: Contribution to journalArticle

  68. Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

    Hivert, M-F., Jablonski, K. A., Perreault, L., Saxena, R., McAteer, J. B., Paul Franks, Hamman, R. F., Kahn, S. E., Haffner, S., Meigs, J. B., Altshuler, D., Knowler, W. C. & Florez, J. C., 2011, In : Diabetes. 60, 4, p. 1340-1348

    Research output: Contribution to journalArticle

  69. Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families

    Holm, P., Rydlander, B., Holger Luthman & Kockum, I., 2004, In : Diabetes. 53, 6, p. 1584-1591

    Research output: Contribution to journalArticle

  70. Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

    Holmkvist, J., Almgren, P., Lyssenko, V., Lindgren, C. M., Karl-Fredrik Eriksson, Isomaa, B., Tuomi, T., Peter Nilsson & Leif Groop, 2008, In : Diabetes. 57, 6, p. 1738-1744

    Research output: Contribution to journalArticle

  71. Bariatric surgery enhances splanchnic vascular responses in patients with type 2 diabetes

    Honka, H., Koffert, J., Kauhanen, S., Teuho, J., Hurme, S., Mari, A., Andreas Lindqvist, Nils Wierup, Leif Groop & Nuutila, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 880-885 6 p.

    Research output: Contribution to journalArticle

  72. Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.

    Huang, X., Vaag, A., Emma A Nilsson, Hansson, M., Bo Ahrén & Leif Groop, 2003, In : Diabetes. 52, 9, p. 2411-2418

    Research output: Contribution to journalArticle

  73. Interferon expression in the pancreases of patients with type I diabetes

    Huang, X., Yuan, J., Goddard, A., Foulis, A., James, R. F. L., Åke Lernmark, Pujol-Borrell, R., Rabinovitch, A., Somoza, N. & Stewart, T. A., 1995 Jan 1, In : Diabetes. 44, 6, p. 658-664

    Research output: Contribution to journalArticle

  74. Quantitative determination of islet cell surface antibodies using 125I-protein A

    Huen, A. H. J., Haneda, M., Freedman, Z., A. Lernmark & Rubenstein, A. H., 1983 Jun 16, In : Diabetes. 32, 5 I, p. 460-465 6 p.

    Research output: Contribution to journalArticle

  75. IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies

    Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Doring, A., Lowel, H., Lieb, W., Hengstenberg, C., Rathmann, W. & 25 othersMartin, S., Stephens, J. W., Ireland, H., Mather, H., Miller, G. J., Stringham, H. M., Boehnke, M., Tuomilehto, J., Boeing, H., Mohlig, M., Spranger, J., Pfeiffer, A., Wernstedt, I., Niklason, A., Lopez-Bermejo, A., Fernandez-Real, J-M., Hanson, R. L., Gallart, L., Vendrell, J., Tsiavou, A., Hatziagelaki, E., Humphries, S. E., Wichmann, H. -E., Herder, C. & Illig, T., 2006, In : Diabetes. 55, 10, p. 2915-2921

    Research output: Contribution to journalArticle

  76. Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

    Ivarsson, R., Quintens, R., Dejonghe, S., Tsukamoto, K., Veld, P., Erik Renström & Schuit, FC., 2005, In : Diabetes. 54, 7, p. 2132-2142

    Research output: Contribution to journalArticle

  77. Nonislet pancreatic autoantibodies in sibship with permanent neonatal insulin-dependent diabetes mellitus

    Ivarsson, S. A., Marner, B., A. Lernmark & Nilsson, K. O., 1988 Jan 1, In : Diabetes. 37, 3, p. 347-350 4 p.

    Research output: Contribution to journalArticle

  78. Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program

    Jablonski, K. A., McAteer, J. B., de Bakker, P. I., Paul Franks, Pollin, T. I., Hanson, R. L., Saxena, R., Fowler, S., Shuldiner, A. R., Knowler, W. C., Altshuler, D. & Florez, J. C., 2010, In : Diabetes. Oct, 59(10), p. 2672-2681

    Research output: Contribution to journalArticle

  79. Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease, and hypertension

    Ji, Y., Yiorkas, A. M., Frau, F., Mook-Kanamori, D., Staiger, H., Thomas, E. L., Atabaki-Pasdar, N., Campbell, A., Tyrrell, J., Jones, S. E., Beaumont, R. N., Wood, A. R., Tuke, M. A., Ruth, K. S., Mahajan, A., Murray, A., Freathy, R. M., Weedon, M. N., Hattersley, A. T., Hayward, C. & 11 othersMachann, J., Häring, H. U., Paul Franks, de Mutsert, R., Pearson, E., Stefan, N., Frayling, T. M., Allebrandt, K. V., Bell, J. D., Blakemore, A. I. & Yaghootkar, H., 2019, In : Diabetes. 68, 1, p. 207-219 13 p.

    Research output: Contribution to journalArticle

  80. Variation in the adiponutrin gene influences its expression and associates with obesity.

    Johansson, L., Hoffstedt, J., Parikh, H., Emma A Nilsson, Wabitsch, M., Bondeson, A-G., Jan Hedenbro, Tornqvist, H., Leif Groop & Martin Ridderstråle, 2006, In : Diabetes. 55, 3, p. 826-833

    Research output: Contribution to journalArticle

  81. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

    Johansson, H., Lukinius, A., Moberg, L., Lundgren, T., Berne, C., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibe, A., Tufveson, G., Ekdahl, KN., Elgue, G., Korsgren, O. & Nilsson, B., 2005, In : Diabetes. 54, 6, p. 1755-1762

    Research output: Contribution to journalArticle

  82. Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.

    Jonsson, A., Ladenvall, C., Ahluwalia, T. S., Jasmina Kravic, Krus, U., Taneera, J., Isomaa, B., Tuomi, T., Erik Renström, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 8, p. 2978-2983

    Research output: Contribution to journalArticle

  83. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

    Jonsson, A., Isomaa, B., Tuomi, T., Taneera, J., S Albert Salehi, Peter Nilsson, Leif Groop & Valeriya Lyssenko, 2009, In : Diabetes. 58, 10, p. 2409-2413

    Research output: Contribution to journalArticle

  84. Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes

    Kacerovsky-Bielesz, G., Chmelik, M., Charlotte Ling, Pokan, R., Szendroedi, J., Farukuoye, M., Kacerovsky, M., Schmid, A. I., Gruber, S., Wolzt, M., Moser, E., Pacini, G., Smekal, G., Leif Groop & Roden, M., 2009, In : Diabetes. 58, 6, p. 1333-1341

    Research output: Contribution to journalArticle

  85. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat

    Kaldunski, M. L., Jia, S., Geoffrey, R., Basken, J., Prosser, S., Kansra, S., Mordes, J. P., Åke Lernmark, Wang, X. & Hessner, M. J., 2010, In : Diabetes. 59, 10, p. 2375-2385 11 p.

    Research output: Contribution to journalArticle

  86. Immunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release

    Kanatsuna, T., Baekkeskov, S., A. Lernmark & Ludvigsson, J., 1983 Jan 1, In : Diabetes. 32, 6 I, p. 520-524 5 p.

    Research output: Contribution to journalArticle

  87. Block in insulin release from column-perifused pancreatic β-cells induced by islet cell surface antibodies and complement

    Kanatsuna, T., A. Lernmark, Rubenstein, A. H. & Steiner, D. F., 1981 Jan 1, In : Diabetes. 30, 3, p. 231-234 4 p.

    Research output: Contribution to journalArticle

  88. Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant A 14-Cohort Meta-analysis

    Kanoni, S., Nettleton, J. A., Hivert, M-F., Ye, Z., van Rooij, F. J. A., Shungin, D., Sonestedt, E., Ngwa, J. S., Wojczynski, M. K., Lemaitre, R. N., Gustafsson, S., Anderson, J. S., Tanaka, T., Hindy, G., Saylor, G., Renstrom, F., Bennett, A. J., van Duijn, C. M., Florez, J. C., Fox, C. S. & 36 othersHofman, A., Hoogeveen, R. C., Houston, D. K., Hu, F. B., Jacques, P. F., Johansson, I., Lind, L., Liu, Y., McKeown, N., Ordovas, J., Pankow, J. S., Sijbrands, E. J. G., Syvanen, A-C., Uitterlinden, A. G., Yannakoulia, M., Zillikens, M. C., Wareham, N. J., Prokopenko, I., Bandinelli, S., Forouhi, N. G., Cupples, L. A., Loos, R. J., Hallmans, G., Dupuis, J., Langenberg, C., Ferrucci, L., Kritchevsky, S. B., McCarthy, M. I., Ingelsson, E., Borecki, I. B., Witteman, J. C. M., Marju Orho-Melander, Siscovick, D. S., Meigs, J. B., Paul Franks & Dedoussis, G. V., 2011, In : Diabetes. 60, 9, p. 2407-2416

    Research output: Contribution to journalArticle

  89. Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-Mr autoantibodies

    Karlsen, A. E., Hagopian, W. A., Petersen, J. S., Boel, E., Dyrberg, T., Grubin, C. E., Michelsen, B. K., Madsen, O. D. & Åke Lernmark, 1992 Jan 1, In : Diabetes. 41, 10, p. 1355-1359

    Research output: Contribution to journalArticle

  90. Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

    Keildson, S., Fadista, J., Ladenvall, C., Hedman, A. K., Elgzyri, T., Small, K. S., Grundberg, E., Nica, A. C., Glass, D., Richards, J. B., Barrett, A., Nisbet, J., Zheng, H-F., Rönn, T., Ström, K., Eriksson, K-F., Prokopenko, I., Spector, T. D., Dermitzakis, E. T., Deloukas, P. & 6 othersMcCarthy, M. I., Rung, J., Leif Groop, Paul Franks, Lindgren, C. M. & Ola Hansson, 2014, In : Diabetes. 63, 3, p. 1154-1165

    Research output: Contribution to journalArticle

  91. The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes:A TEDDY Study Report: A TEDDY Study Report

    Krischer, J. P., Liu, X., Åke Lernmark, Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A-G., Akolkar, B. & TEDDY Study Group, 2017, In : Diabetes. 66, 12, p. 3122-3129

    Research output: Contribution to journalArticle

  92. Circulating fetuin - A and risk of type 2 diabetes: A mendelian randomization analysis

    Kröger, J., Meidtner, K., Stefan, N., Guevara, M., Kerrison, N. D., Ardanaz, E., Aune, D., Boeing, H., Dorronsoro, M., Dow, C., Fagherazzi, G., Franks, P. W., Freisling, H., Gunter, M. J., Huerta, J. M., Kaaks, R., Key, T. J., Khaw, K. T., Krogh, V., Kühn, T. & 23 othersMancini, F. R., Mattiello, A., Peter M. Nilsson, Olsen, A., Overvad, K., Palli, D., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Salamanca-Fernández, E., Sluijs, I., Spijkerman, A. M. W., Tjonneland, A., Tsilidis, K. K., Tumino, R., Van Der Schouw, Y. T., Forouhi, N. G., Sharp, S. J., Langenberg, C., Riboli, E., Schulze, M. B. & Wareham, N. J., 2018 Jun 1, In : Diabetes. 67, 6, p. 1200-1205 6 p.

    Research output: Contribution to journalArticle

  93. Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance

    Kurucz, I., Morva, A., Vaag, A., Karl-Fredrik Eriksson, Huang, X., Leif Groop & Koranyi, L., 2002, In : Diabetes. 51, 4, p. 1102-1109

    Research output: Contribution to journalArticle

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