Diabetes, 1939-327X

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  1. 2008
  2. Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes

    Cervin, C., Valeriya Lyssenko, Bakhtadze, E., Eero Lindholm, Peter Nilsson, Tuomi, T., Corrado Cilio & Leif Groop, 2008, In : Diabetes. 57, 5, p. 1433-1437

    Research output: Contribution to journalArticle

  3. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the Type 1 Diabetes Genetics Consortium families

    Erlich, H., Valdes, A. M., Noble, J., Joyce Carlson, Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., Lavant, E., Louey, A. & Moonsamy, P., 2008, In : Diabetes. 57, 4, p. 1084-1092

    Research output: Contribution to journalArticle

  4. 2007
  5. Association studies of BMI and type 2 diabetes in the neuropeptide y pathway - A possible role for NPY2R as a candidate gene for type 2 diabetes in men

    Campbell, C. D., Lyon, H. N., Nemesh, J., Drake, J. A., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R. S., Ardlie, K. G., Leif Groop & Hirschhorn, J. N., 2007, In : Diabetes. 56, 5, p. 1460-1467

    Research output: Contribution to journalArticle

  6. Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes

    Winckler, W., Weedon, M. N., Graham, R. R., McCarrolll, S. A., Purcell, S., Almgren, P., Tuomi, T., Gaudet, D., Kristina Bengtsson Boström, Walker, M., Hitman, G., Hattersley, A. T., McCarthy, M. I., Ardlie, K. G., Hirschhorn, J. N., Daly, M. J., Frayling, T. M., Groop, L. & Altshuler, D., 2007, In : Diabetes. 56, 3, p. 685-693

    Research output: Contribution to journalArticle

  7. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

    Cabric, S., Sanchez, J., Lundgren, T., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibell, A., Tufveson, G., Larsson, R., Korsgren, O. & Nilsson, B., 2007, In : Diabetes. 56, 8, p. 2008-2015

    Research output: Contribution to journalArticle

  8. Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

    Olofsson, C., Collins, S., Bengtsson, M., Lena Eliasson, S Albert Salehi, Shimomura, K., Tarasov, A., Cecilia Holm, Ashcroft, F. & Rorsman, P., 2007, In : Diabetes. 56, 7, p. 1888-1897

    Research output: Contribution to journalArticle

  9. 2006
  10. {beta}-Cell Lipases and Insulin Secretion.

    Malin Fex, Lucas, S., Sörhede Winzell, M., Bo Ahrén, Cecilia Holm & Hindrik Mulder, 2006, In : Diabetes. 55, Suppl 2, p. S24-S31

    Research output: Contribution to journalArticle

  11. CART Regulates Islet Hormone Secretion and Is Expressed in the {beta}-Cells of Type 2 Diabetic Rats.

    Nils Wierup, Maria Björkqvist, Kuhar, M. J., Hindrik Mulder & Sundler, F., 2006, In : Diabetes. 55, 2, p. 305-311

    Research output: Contribution to journalArticle

  12. Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

    Saxena, R., Gianniny, L., Burtt, N. P., Valeriya Lyssenko, Giuducci, C., Marketa Sjögren, Florez, J. C., Almgren, P., Isomaa, B., Marju Orho-Melander, Lindblad, U., Daly, M. J., Tuomi, T., Hirschhorn, J. N., Ardlie, K. G., Leif Groop & Altshuler, D., 2006, In : Diabetes. 55, 10, p. 2890-2895

    Research output: Contribution to journalArticle

  13. Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity

    Lyon, H. N., Florez, J. C., Bersaglieri, T., Saxena, R., Winckler, W., Almgren, P., Lindblad, U., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R., Ardlie, K. G., Daly, M. J., Altshuler, D., Leif Groop & Hirschhorn, J. N., 2006, In : Diabetes. 55, 11, p. 3180-3184

    Research output: Contribution to journalArticle

  14. Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic {beta}-Cell Fate.

    Taneera, J., Anders Rosengren, Erik Renström, Nygren, J., Serup, P., Rorsman, P. & Jacobsen, S. E. W., 2006, In : Diabetes. 55, 2, p. 290-296

    Research output: Contribution to journalArticle

  15. Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function

    Sorensen, H., Sörhede Winzell, M., Brand, C. L., Fosgerau, K., Gelling, R. W., Nishimura, E. & Bo Ahrén, 2006, In : Diabetes. 55, 12, p. 3463-3469

    Research output: Contribution to journalArticle

  16. Haplotype structures and large-scale association testing of the 5 ' AMP-activated protein kinase genes PRK4A2, PRKAB1, and PRK4B1 with type 2 diabetes

    Sun, MW., Lee, JY., de Bakker, PIW., Burtt, NP., Almgren, P., Lennart Råstam, Tuomi, T., Gaudet, D., Daly, MJ., Hirschhorn, JN., Altshuler, D., Groop, L. & Florez, JC., 2006, In : Diabetes. 55, 3, p. 849-855

    Research output: Contribution to journalArticle

  17. High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

    Florez, JC., Wiltshire, S., Agapakis, CM., Burtt, NP., de Bakker, PIW., Almgren, P., Bostrom, KB., Tuomi, T., Gaudet, D., Daly, MJ., Hirschhorn, JN., McCarthy, MI., Altshuler, D. & Leif Groop, 2006, In : Diabetes. 55, 1, p. 128-135

    Research output: Contribution to journalArticle

  18. IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies

    Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Doring, A., Lowel, H., Lieb, W., Hengstenberg, C., Rathmann, W. & 25 othersMartin, S., Stephens, J. W., Ireland, H., Mather, H., Miller, G. J., Stringham, H. M., Boehnke, M., Tuomilehto, J., Boeing, H., Mohlig, M., Spranger, J., Pfeiffer, A., Wernstedt, I., Niklason, A., Lopez-Bermejo, A., Fernandez-Real, J-M., Hanson, R. L., Gallart, L., Vendrell, J., Tsiavou, A., Hatziagelaki, E., Humphries, S. E., Wichmann, H. -E., Herder, C. & Illig, T., 2006, In : Diabetes. 55, 10, p. 2915-2921

    Research output: Contribution to journalArticle

  19. Increased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria

    Nosadini, R., Velussi, M., Brocco, E., Abaterusso, C., Carraro, A., Piarulli, F., Morgia, G., Satta, A., Faedda, R., Abhyankar, A., Holger Luthman & Tonolo, G., 2006, In : Diabetes. 55, 1, p. 234-239

    Research output: Contribution to journalArticle

  20. Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.

    Fuller, J., Kwitek, A. E., Hawkins, T. J., Moralejo, D. H., Lu, W., Tupling, T. D., Macmurray, A. J., Borchardt, G., Hasinoff, M. & Åke Lernmark, 2006, In : Diabetes. 55, p. 3351-3357

    Research output: Contribution to journalArticle

  21. In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse - Pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

    Henquin, JC., Nenquin, M., Stiernet, P. & Bo Ahrén, 2006, In : Diabetes. 55, 2, p. 441-451

    Research output: Contribution to journalArticle

  22. Mature-onset obesity in interleukin-1 receptor I knockout mice

    Garcia, MC., Wernstedt, I., Berndtsson, A., Enge, M., Bell, M., Hultgren, O., Horn, M., Bo Ahrén, Enerback, S., Ohlsson, C., Wallenius, V. & Jansson, JO., 2006, In : Diabetes. 55, 5, p. 1205-1213

    Research output: Contribution to journalArticle

  23. Neuropeptides and the regulation of islet function.

    Bo Ahrén, Nils Wierup & Sundler, F., 2006, In : Diabetes. 55, Suppl 2, p. S98-S107

    Research output: Contribution to journalArticle

  24. Paradoxical stimulation of glucagon secretion by high glucose concentrations

    S Albert Salehi, Vieira, E. & Gylfe, E., 2006, In : Diabetes. 55, 8, p. 2318-2323

    Research output: Contribution to journalArticle

  25. The Kruppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people

    Florez, J. C., Saxena, R., Winckler, W., Burtt, N. P., Almgren, P., Kristina Bengtsson Boström, Tuomi, T., Gaudet, D., Ardlie, K. G., Daly, M. J., Altshuler, D., Hirschhorn, J. N. & Leif Groop, 2006, In : Diabetes. 55, 12, p. 3620-3624

    Research output: Contribution to journalArticle

  26. Variation in the adiponutrin gene influences its expression and associates with obesity.

    Johansson, L., Hoffstedt, J., Parikh, H., Emma A Nilsson, Wabitsch, M., Bondeson, A-G., Jan Hedenbro, Tornqvist, H., Leif Groop & Martin Ridderstråle, 2006, In : Diabetes. 55, 3, p. 826-833

    Research output: Contribution to journalArticle

  27. 2005
  28. Adipocyte lipases and defect of lipolysis in human obesity

    Langin, D., Dicker, A., Tavernier, G., Hoffstedt, J., Mairal, A., Ryden, M., Arner, E., Sicard, A., Jenkins, C. M., Viguerie, N., van Harmelen, V., Gross, R. W., Cecilia Holm & Arner, P., 2005, In : Diabetes. 54, 11, p. 3190-3197

    Research output: Contribution to journalArticle

  29. Altered transcapillary escape of albumin and microalbuminuria reflects two different pathogenetic mechanisms

    Nosadini, R., Velussi, M., Brocco, E., Abaterusso, C., Piarulli, F., Morgia, G., Satta, A., Faedda, R., Abhyankar, A., Holger Luthman & Tonolo, G., 2005, In : Diabetes. 54, 1, p. 228-233

    Research output: Contribution to journalArticle

  30. Association of common variation in the HNF1 alpha gene region with risk of type 2 diabetes

    Winckler, W., Burtt, N. P., Holmkvist, J., Cervin, C., de Bakker, P. I. W., Sun, M., Almgren, P., Tuomi, T., Gaudet, D., Hudson, T. J., Ardlie, K. G., Daly, M. J., Hirschhorn, J. N., Altshuler, D. & Leif Groop, 2005, In : Diabetes. 54, 8, p. 2336-2342

    Research output: Contribution to journalArticle

  31. Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people

    Florez, J. C., Agapakis, C. M., Burtt, N. P., Sun, M., Almgren, P., Lennart Råstam, Tuomi, T., Gaudet, D., Hudson, T. J., Daly, M. J., Ardlie, K. G., Hirschhorn, J. N., Leif Groop & Altshuler, B., 2005, In : Diabetes. 54, 6, p. 1884-1891

    Research output: Contribution to journalArticle

  32. Association testing of variants in the hepatocyte nuclear factor 4 alpha gene with risk of type 2 diabetes in 7,883 people

    Winckler, W., Graham, R. R., de Bakker, P. I. W., Sun, M., Almgren, P., Tuomi, T., Gaudet, D., Hudson, T. J., Ardlie, K. G., Daly, M. J., Hirschhorn, J. N., Leif Groop & Altshuler, D., 2005, In : Diabetes. 54, 3, p. 886-892

    Research output: Contribution to journalArticle

  33. Autoantibodies in diabetes.

    Pihoker, C., Gilliam, L. K., Hampe, C. S. & Åke Lernmark, 2005, In : Diabetes. 54, Dec, p. 52-61

    Research output: Contribution to journalArticle

  34. Complement c3 is a risk factor for the development of diabetes: a population-based cohort study.

    Gunnar Engström, Bo Hedblad, Karl-Fredrik Eriksson, Janzon, L. & Lindgärde, F., 2005, In : Diabetes. 54, 2, p. 570-575

    Research output: Contribution to journalArticle

  35. Genetic and Nongenetic Regulation of CAPN10 mRNA Expression in Skeletal Muscle.

    Emma A Nilsson, Poulsen, P., Storgaard, H., Almgren, P., Charlotte Ling, Jensen, C. B., Madsbad, S., Leif Groop, Vaag, A. & Martin Ridderstråle, 2005, In : Diabetes. 54, 10, p. 3015-3020

    Research output: Contribution to journalArticle

  36. Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia

    Bohlooly, M., Olsson, B., Bruder, CEG., Linden, D., Sjogren, K., Bjursell, M., Egecioglu, E., Svensson, L., Brodin, P., Waterton, JC., Isaksson, OGP., Sundler, F., Bo Ahrén, Ohlsson, C., Oscarsson, J. & Tornell, J., 2005, In : Diabetes. 54, 1, p. 51-62

    Research output: Contribution to journalArticle

  37. Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility

    S Albert Salehi, Quader, SS., Grapengiesser, E. & Hellman, B., 2005, In : Diabetes. 54, 7, p. 2126-2131

    Research output: Contribution to journalArticle

  38. Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment.

    Stenström, G., Anders Gottsäter, Bakhtadze, E., Berger, B. & Sundkvist, G., 2005, In : Diabetes. 54, Suppl 2, p. S68-S72

    Research output: Contribution to journalArticle

  39. Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K+ Channel Activity

    Lin, C-W., Yan, F., Shimamura, S., Barg, S. & Shyng, S-L., 2005, In : Diabetes. 54, 10, p. 2852-2858

    Research output: Contribution to journalArticle

  40. Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes.

    Lyssenko, V., Almgren, P., Dragi Anevski, Perfekt, R., Lahti, K., Nissén, M., Isomaa, B., Forsen, B., Homström, N., Saloranta, C., Taskinen, M-R., Leif Groop & Tuomi, T., 2005, In : Diabetes. 54, 1, p. 166-174

    Research output: Contribution to journalArticle

  41. Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

    Ivarsson, R., Quintens, R., Dejonghe, S., Tsukamoto, K., Veld, P., Erik Renström & Schuit, FC., 2005, In : Diabetes. 54, 7, p. 2132-2142

    Research output: Contribution to journalArticle

  42. Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat {beta}-Cells.

    MacDonald, P., Obermüller, S., Vikman, J., Galvanovskis, J., Rorsman, P. & Lena Eliasson, 2005, In : Diabetes. 54, 3, p. 736-743

    Research output: Contribution to journalArticle

  43. Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing {beta}-Cell-Like Cells.

    Brolén, G., Heins, N., Edsbagge, J. & Semb, H., 2005, In : Diabetes. 54, 10, p. 2867-2874

    Research output: Contribution to journalArticle

  44. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

    Johansson, H., Lukinius, A., Moberg, L., Lundgren, T., Berne, C., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibe, A., Tufveson, G., Ekdahl, KN., Elgue, G., Korsgren, O. & Nilsson, B., 2005, In : Diabetes. 54, 6, p. 1755-1762

    Research output: Contribution to journalArticle

  45. Type 1 Diabetes: Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

    Concannon, P., Erlich, HA., Julier, C., Morahan, G., Nerup, J., Pociot, F., Todd, JA., Rich, SS., Type 1 Diabetes Genetics Consortium, T. & Joyce Carlson, 2005, In : Diabetes. 54, p. 2995-3001

    Research output: Contribution to journalArticle

  46. 2004
  47. Aged Transgenic Mice With Increased Glucocorticoid Sensitivity in Pancreatic beta-Cells Develop Diabetes.

    Davani, B., Portwood, N., Bryzgalova, G., Reimer, M. K., Heiden, T., Ostenson, C-G., Okret, S., Bo Ahrén, Efendic, S. & Khan, A., 2004, In : Diabetes. 53, Suppl 1, p. S51-S59

    Research output: Contribution to journalArticle

  48. Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes

    Florez, JC., Marketa Sjögren, Burtt, N., Marju Orho-Melander, Schayer, S., Sun, M., Almgren, P., Lindblad, U., Tuomi, T., Gaudet, D., Hudson, TJ., Daly, MJ., Ardlie, KG., Hirschhorn, JN., Altshuler, D. & Leif Groop, 2004, In : Diabetes. 53, 12, p. 3313-3318

    Research output: Contribution to journalArticle

  49. Cosegregation of MIDD and MODY in a Pedigree: Functional and Clinical Consequences.

    Cervin, C., Liljeström, B., Tuomi, T., Heikkinen, S., Tapanainen, J. S., Leif Groop & Corrado Cilio, 2004, In : Diabetes. 53, 7, p. 1894-1899

    Research output: Contribution to journalArticle

  50. Glucose Inhibition of Glucagon Secretion From Rat alpha-Cells Is Mediated by GABA Released From Neighboring beta-Cells.

    Anna Wendt, Birnir, B., Buschard, K., Gromada, J., S Albert Salehi, Sewing, S., Rorsman, P. & Braun, M., 2004, In : Diabetes. 53, 4, p. 1038-1045

    Research output: Contribution to journalArticle

  51. Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region.

    Florez, J. C., Burtt, N., De Bakker, P. I. W., Almgren, P., Tuomi, T., Holmkvist, J., Gaudet, D., Hudson, T. J., Schaffner, S. F., Daly, M. J., Hirschhorn, J. N., Leif Groop & Altshuler, D., 2004, In : Diabetes. 53, 5, p. 1360-1368

    Research output: Contribution to journalArticle

  52. Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion.

    Hindrik Mulder, Yang, S., Sörhede Winzell, M., Cecilia Holm & Bo Ahrén, 2004, In : Diabetes. 53, 1, p. 122-128

    Research output: Contribution to journalArticle

  53. Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families

    Holm, P., Rydlander, B., Holger Luthman & Kockum, I., 2004, In : Diabetes. 53, 6, p. 1584-1591

    Research output: Contribution to journalArticle