Diabetes, 1939-327X

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  1. Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The environmental determinants of diabetes in the young study

    Helena Elding Larsson, Vehik, K., Haller, M. J., Liu, X., Akolkar, B., Hagopian, W., Krischer, J., Åke Lernmark, She, J. X., Simell, O., Toppari, J., Ziegler, A. G. & Rewers, M., 2016 Jul 1, In : Diabetes. 65, 7, p. 1988-1995 8 p.

    Research output: Contribution to journalArticle

  2. Decreased cord-blood phospholipids in young age at onset type 1 diabetes.

    Daria La Torre, Seppänen-Laakso, T., Helena Larsson, Hyötyläinen, T., Sten Ivarsson, Åke Lernmark & Oresic, M., 2013, In : Diabetes. 62, 11, p. 3951-3956

    Research output: Contribution to journalArticle

  3. Recombinant human platelet-activating factor acetylhydrolase reduces the frequency of diabetes in the diabetes-prone BB rat

    Lee, E. S., Jiang, J., Sund, G. C., Simonson, W. T., Graham, J., Dietsch, G., Schimpf, B., Bieg, S., Peterman, G. & Åke Lernmark, 1999 Jan 1, In : Diabetes. 48, 1, p. 43-49

    Research output: Contribution to journalArticle

  4. The streetlight effect-is there light at the end of the tunnel?

    Åke Lernmark, 2015, In : Diabetes. 64, 4, p. 1105-1107

    Research output: Contribution to journalDebate/Note/Editorial

  5. Depleting T cells in newly diagnosed autoimmune (type 1) diabetes--are we getting anywhere?

    Åke Lernmark, 2013, In : Diabetes. 62, 11, p. 3669-3670

    Research output: Contribution to journalDebate/Note/Editorial

  6. Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K+ Channel Activity

    Lin, C-W., Yan, F., Shimamura, S., Barg, S. & Shyng, S-L., 2005, In : Diabetes. 54, 10, p. 2852-2858

    Research output: Contribution to journalArticle

  7. Characterization of the annexin I gene and evaluation of its role in type 2 diabetes

    Lindgren, C. M., Ramelius, A., Marju Orho-Melander, Almgren, P. & Leif Groop, 2001, In : Diabetes. 50, 10, p. 2402-2405

    Research output: Contribution to journalArticle

  8. Contribution of known and unknown susceptibility genes to early-onset diabetes in scandinavia: evidence for heterogeneity.

    Lindgren, C., Widén, E., Tuomi, T., Li, H., Almgren, P., Kanninen, T., Olle Melander, Weng, J., Lehto, M. & Leif Groop, 2002, In : Diabetes. 51, 5, p. 1609-1617

    Research output: Contribution to journalArticle

  9. Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

    Charlotte Ling & Leif Groop, 2009, In : Diabetes. 58, 12, p. 2718-2725

    Research output: Contribution to journalReview article

  10. Impaired Tethering and Fusion of GLUT4 Vesicles in Insulin-Resistant Human Adipose Cells

    Lizunov, V. A., Lee, J-P., Skarulis, M. C., Zimmerberg, J., Cushman, S. W. & Karin Stenkula, 2013, In : Diabetes. 62, 9, p. 3114-3119

    Research output: Contribution to journalArticle

  11. GAD Antibody Positivity Predicts Type 2 Diabetes in an Adult Population

    Lundgren, V. M., Isomaa, B., Valeriya Lyssenko, Esa Laurila, Korhonen, P., Leif Groop & Tuomi, T., 2010, In : Diabetes. 59, 2, p. 416-422

    Research output: Contribution to journalArticle

  12. Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity

    Lyon, H. N., Florez, J. C., Bersaglieri, T., Saxena, R., Winckler, W., Almgren, P., Lindblad, U., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R., Ardlie, K. G., Daly, M. J., Altshuler, D., Leif Groop & Hirschhorn, J. N., 2006, In : Diabetes. 55, 11, p. 3180-3184

    Research output: Contribution to journalArticle

  13. Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

    Lyssenko, V., Eliasson, L., Kotova, O., Pilgaard, K., Wierup, N., Salehi, S. A., Wendt, A., Jonsson, A., De Marinis, Y. Z., Berglund, L., Taneera, J., Balhuizen, A., Hansson, O., Osmark, P., Dunér, P., Brons, C., Stancakova, A., Kuusisto, J., Bugliani, M., Saxena, R. & 19 othersEmma Ahlqvist, Kieffer, T. J., Tuomi, T., Isomaa, B., Olle Melander, Emily Sonestedt, Marju Orho-Melander, Peter Nilsson, Bonetti, S., Bonadonna, R., Miccoli, R., DelPrato, S., Marchetti, P., Madsbad, S., Poulsen, P., Vaag, A., Laakso, M., Maria Gomez & Leif Groop, 2011, In : Diabetes. 60, 9, p. 2424-2433

    Research output: Contribution to journalArticle

  14. Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes.

    Lyssenko, V., Almgren, P., Dragi Anevski, Perfekt, R., Lahti, K., Nissén, M., Isomaa, B., Forsen, B., Homström, N., Saloranta, C., Taskinen, M-R., Leif Groop & Tuomi, T., 2005, In : Diabetes. 54, 1, p. 166-174

    Research output: Contribution to journalArticle

  15. Evaluation of A2BP1 as an Obesity Gene

    Ma, L., Hanson, R. L., Traurig, M. T., Muller, Y. L., Kaur, B. P., Perez, J. M., Meyre, D., Fu, M., Koerner, A., Paul Franks, Kiess, W., Kobes, S., Knowler, W. C., Kovacs, P., Froguel, P., Shuldiner, A. R., Bogardus, C. & Baler, L. J., 2010, In : Diabetes. 59, 11, p. 2837-2845

    Research output: Contribution to journalArticle

  16. Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat {beta}-Cells.

    MacDonald, P., Obermüller, S., Vikman, J., Galvanovskis, J., Rorsman, P. & Lena Eliasson, 2005, In : Diabetes. 54, 3, p. 736-743

    Research output: Contribution to journalArticle

  17. Dimethylglycine Deficiency and the Development of Diabetes mellitus.

    Martin Magnusson, Wang, T. J., Clish, C., Gunnar Engström, Peter Nilsson, Gerszten, R. E. & Olle Melander, 2015, In : Diabetes. 64, 8, p. 3010-3016

    Research output: Contribution to journalArticle

  18. Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats

    Markholst, H., Klaff, L. J., Klöppel, G., Åke Lernmark, Mordes, J. P. & Palmer, J., 1990 Jan 1, In : Diabetes. 39, 6, p. 720-727 8 p.

    Research output: Contribution to journalArticle

  19. Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes

    Mastrolia, V., Flucher, S. M., Obermair, G. J., Drach, M., Hofer, H., Erik Renström, Schwartz, A., Striessnig, J., Flucher, B. E. & Tuluc, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 897-907 11 p.

    Research output: Contribution to journalArticle

  20. Microphthalmia transcription factor regulates pancreatic β-cell function

    Mazur, M., Winkler, M., Ganic, E., Colberg, J. K., Johansson, J., Bennet, H., Malin Fex, Nuber, U. & Isabella Artner, 2013, In : Diabetes. 62, 8, p. 2834-2842

    Research output: Contribution to journalArticle

  21. Early, selective, and marked loss of sympathetic nerves from the islets of BioBreeder diabetic rats.

    Mei, Q., Mundinger, TO., Åke Lernmark & Taborsky, GJ. J., 2002, In : Diabetes. 51, 10, p. 2997-3002

    Research output: Contribution to journalArticle

  22. C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes.

    Mei, J., Stenson, L., Landström, T., Cecilia Holm, Brindley, D., Manganiello, V. & Eva Degerman, 2002, In : Diabetes. 51, 3, p. 631-637

    Research output: Contribution to journalArticle

  23. Kinetics-effect relations of insulin-releasing drugs in patients with type 2 diabetes

    Melander, A., 2004, In : Diabetes. 53, Suppl., p. S151-S155

    Research output: Contribution to journalArticle

  24. Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells

    Hindrik Mulder, Stensson Holst, L., Svensson, H., Eva Degerman, Sundler, F., Bo Ahrén, Rorsman, P. & Cecilia Holm, 1999, In : Diabetes. 48, 1, p. 228-232

    Research output: Contribution to journalArticle

  25. Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion.

    Hindrik Mulder, Yang, S., Sörhede Winzell, M., Cecilia Holm & Bo Ahrén, 2004, In : Diabetes. 53, 1, p. 122-128

    Research output: Contribution to journalArticle

  26. Functional investigations of HNF1A identify rare variants as risk factors for type 2 diabetes in the general population

    Najmi, L. A., Aukrust, I., Flannick, J., Molnes, J., Burtt, N., Molven, A., Leif Groop, Altshuler, D., Johansson, S., Bjørkhaug, L. & Njølstad, P. R., 2017 Feb 1, In : Diabetes. 66, 2, p. 335-346 12 p.

    Research output: Contribution to journalArticle

  27. Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.

    Emma A Nilsson, Jansson, P. A., Alexander Perfilyev, Petr Volkov, Pedersen, M., Svensson, M. K., Poulsen, P., Ribel-Madsen, R., Pedersen, N. L., Almgren, P., Fadista, J., Tina Rönn, Klarlund-Pedersen, B., Scheele, C., Allan Vaag & Charlotte Ling, 2014, In : Diabetes. 63, 9, p. 2962-2976

    Research output: Contribution to journalArticle

  28. Genetic and Nongenetic Regulation of CAPN10 mRNA Expression in Skeletal Muscle.

    Emma A Nilsson, Poulsen, P., Storgaard, H., Almgren, P., Charlotte Ling, Jensen, C. B., Madsbad, S., Leif Groop, Vaag, A. & Martin Ridderstråle, 2005, In : Diabetes. 54, 10, p. 3015-3020

    Research output: Contribution to journalArticle

  29. HLA Class I and Genetic Susceptibility to Type 1 Diabetes Results From the Type 1 Diabetes Genetics Consortium

    Noble, J. A., Valdes, A. M., Varney, M. D., Joyce Carlson, Moonsamy, P., Fear, A. L., Lane, J. A., Lavant, E., Rappner, R., Louey, A., Concannon, P., Mychaleckyj, J. C. & Erlich, H. A., 2010, In : Diabetes. 59, 11, p. 2972-2979

    Research output: Contribution to journalArticle

  30. Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

    Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Åke Lernmark, Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J. X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

    Research output: Contribution to journalArticle

  31. Altered transcapillary escape of albumin and microalbuminuria reflects two different pathogenetic mechanisms

    Nosadini, R., Velussi, M., Brocco, E., Abaterusso, C., Piarulli, F., Morgia, G., Satta, A., Faedda, R., Abhyankar, A., Holger Luthman & Tonolo, G., 2005, In : Diabetes. 54, 1, p. 228-233

    Research output: Contribution to journalArticle

  32. Increased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria

    Nosadini, R., Velussi, M., Brocco, E., Abaterusso, C., Carraro, A., Piarulli, F., Morgia, G., Satta, A., Faedda, R., Abhyankar, A., Holger Luthman & Tonolo, G., 2006, In : Diabetes. 55, 1, p. 234-239

    Research output: Contribution to journalArticle

  33. Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

    Olofsson, C., Collins, S., Bengtsson, M., Lena Eliasson, S Albert Salehi, Shimomura, K., Tarasov, A., Cecilia Holm, Ashcroft, F. & Rorsman, P., 2007, In : Diabetes. 56, 7, p. 1888-1897

    Research output: Contribution to journalArticle

  34. Palmitate Stimulation of Glucagon Secretion in Mouse Pancreatic {alpha}-Cells Results From Activation of L-Type Calcium Channels and Elevation of Cytoplasmic Calcium.

    Olofsson, C., Salehi, A., Cecilia Holm & Rorsman, P., 2004, In : Diabetes. 53, 11, p. 2836-2843

    Research output: Contribution to journalArticle

  35. Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors.

    Omar, B. & Bo Ahrén, 2014, In : Diabetes. 63, 7, p. 2196-2202

    Research output: Contribution to journalArticle

  36. Fibroblast Growth Factor 21 (FGF21) and Glucagon Like-Peptide 1 Contribute to Diabetes Resistance in Glucagon Receptor Deficient Mice.

    Omar, B., Andersen, B., Hald, J., Raun, K., Nishimura, E. & Bo Ahrén, 2014, In : Diabetes. 63, 1, p. 101-110

    Research output: Contribution to journalArticle

  37. Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

    Orho-Melander, M., Melander, O., Guiducci, C., Perez-Martinez, P., Corella, D., Roos, C., Tewhey, R., Rieder, M. J., Hall, J., Abecasis, G., Tai, E. S., Welch, C., Arnett, D. K., Lyssenko, V., Lindholm, E., Saxena, R., de Bakker, P. I. W., Burtt, N., Voight, B. F., Hirschhorn, J. N. & 21 othersTucker, K. L., Hedner, T., Tuomi, T., Isomaa, B., Karl-Fredrik Eriksson, Taskinen, M-R., Wahlstrand, B., Hughes, T. E., Parnell, L. D., Lai, C-Q., Berglund, G., Peltonen, L., Vartiainen, E., Jousilahti, P., Havulinna, A. S., Salomaa, V., Peter Nilsson, Groop, L., Altshuler, D., Ordovas, J. M. & Kathiresan, S., 2008, In : Diabetes. 57, 11, p. 3112-3121

    Research output: Contribution to journalArticle

  38. Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.

    Marju Orho-Melander, Klannemark, M., Svensson, M., Martin Ridderstråle, Lindgren, C. & Leif Groop, 2002, In : Diabetes. 51, 8, p. 2658-2664

    Research output: Contribution to journalArticle

  39. Expression of naturally occurring variants in the muscle glycogen synthase gene

    Marju Orho-Melander, Shimomura, H., Sanke, T., Rasmussen, S. K., Nanjo, K., Pedersen, O. & Leif Groop, 1999, In : Diabetes. 48, 4, p. 918-920

    Research output: Contribution to journalArticle

  40. Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia

    Ottosson-Laakso, E., Krus, U., Storm, P., Rashmi B Prasad, Nikolay Oskolkov, Emma Ahlqvist, Fadista, J., Ola Hansson, Leif Groop & Petter Vikman, 2017, In : Diabetes. 66, 12, p. 3013-3028

    Research output: Contribution to journalArticle

  41. Susceptibility to insulin-dependent diabetes defined by restriction enzyme polymorphism of HLA-D region genomic DNA

    Owerbach, D., Hagglof, B., A. Lernmark & Holmgren, G., 1984 Jan 1, In : Diabetes. 33, 10, p. 958-965 8 p.

    Research output: Contribution to journalArticle

  42. Genetic predisposition to weight loss & regain with lifestyle intervention: analyses from the Diabetes Prevention Program & the Look AHEAD randomized controlled trials.

    Papandonatos, G. D., Pan, Q., Pajewski, N. M., Delahanty, L. M., Peter, I., Erar, B., Shafqat Ahmad, Harden, M., Chen, L., Fontanillas, P., Wagenknecht, L. E., Kahn, S. E., Wing, R. R., Jablonski, K. A., Huggins, G. S., Knowler, W. C., Florez, J. C., McCaffery, J. M. & Paul Franks, 2015, In : Diabetes. 64, 12, p. 4312-4321

    Research output: Contribution to journalArticle

  43. A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is located on chromosome 18p11

    Parker, A., Meyer, J., Lewitzky, S., Rennich, J. S., Chan, G., Thomas, J. D., Marju Orho-Melander, Lehtovirta, M., Forsblom, C., Hyrkko, A., Carlsson, M., Lindgren, C. & Leif Groop, 2001, In : Diabetes. 50, 3, p. 675-680

    Research output: Contribution to journalArticle

  44. Differential expression of glutamic acid decarboxylase in rat and human islets

    Petersen, J. S., Russel, S., Marshall, M. O., Kofod, H., Buschard, K., Cambon, N., Karlsen, A. E., Boel, E., Hagopian, W. A., Hejnæs, K. R., Moody, A., Dyrberg, T., Åke Lernmark, Madsen, O. D. & Michelsen, B. K., 1993 Jan 1, In : Diabetes. 42, 3, p. 484-495

    Research output: Contribution to journalArticle

  45. Autoantibodies in diabetes.

    Pihoker, C., Gilliam, L. K., Hampe, C. S. & Åke Lernmark, 2005, In : Diabetes. 54, Dec, p. 52-61

    Research output: Contribution to journalArticle

  46. Spontaneously diabetic BB rats have age-dependent islet β-cell-specific surface antibodies at clinical onset

    Pipeleers, D., Van De Winkel, M., Dyrberg, T. & A. Lernmark, 1987 Dec 1, In : Diabetes. 36, 10, p. 1111-1115

    Research output: Contribution to journalArticle

  47. Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice.

    R, P., P, A., A, G., S, M., XM, Z., S, M., Dan Holmberg & RA, H., 2012, In : Diabetes. 61, 11, p. 2881-2892

    Research output: Contribution to journalArticle

  48. A prospective analysis of islet-cell cytotoxic antibodies in insulin-dependent diabetic children. Transient effects of plasmapheresis

    Rabinovitch, A., MacKay, P., Ludvigsson, J. & A. Lernmark, 1984 Jan 1, In : Diabetes. 33, 3, p. 224-228 5 p.

    Research output: Contribution to journalArticle