Diabetes, 1939-327X

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  1. Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The environmental determinants of diabetes in the young study

    Helena Elding Larsson, Vehik, K., Haller, M. J., Liu, X., Akolkar, B., Hagopian, W., Krischer, J., Åke Lernmark, She, J. X., Simell, O., Toppari, J., Ziegler, A. G. & Rewers, M., 2016 Jul 1, In : Diabetes. 65, 7, p. 1988-1995 8 p.

    Research output: Contribution to journalArticle

  2. Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia

    Bohlooly, M., Olsson, B., Bruder, CEG., Linden, D., Sjogren, K., Bjursell, M., Egecioglu, E., Svensson, L., Brodin, P., Waterton, JC., Isaksson, OGP., Sundler, F., Bo Ahrén, Ohlsson, C., Oscarsson, J. & Tornell, J., 2005, In : Diabetes. 54, 1, p. 51-62

    Research output: Contribution to journalArticle

  3. Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region.

    Florez, J. C., Burtt, N., De Bakker, P. I. W., Almgren, P., Tuomi, T., Holmkvist, J., Gaudet, D., Hudson, T. J., Schaffner, S. F., Daly, M. J., Hirschhorn, J. N., Leif Groop & Altshuler, D., 2004, In : Diabetes. 53, 5, p. 1360-1368

    Research output: Contribution to journalArticle

  4. Haplotype structures and large-scale association testing of the 5 ' AMP-activated protein kinase genes PRK4A2, PRKAB1, and PRK4B1 with type 2 diabetes

    Sun, MW., Lee, JY., de Bakker, PIW., Burtt, NP., Almgren, P., Lennart Råstam, Tuomi, T., Gaudet, D., Daly, MJ., Hirschhorn, JN., Altshuler, D., Groop, L. & Florez, JC., 2006, In : Diabetes. 55, 3, p. 849-855

    Research output: Contribution to journalArticle

  5. Hepatic DPP4 DNA methylation associates with fatty liver

    Baumeier, C., Saussenthaler, S., Kammel, A., Jähnert, M., Schlüter, L., Hesse, D., Canouil, M., Lobbens, S., Caiazzo, R., Raverdy, V., Pattou, F., Nilsson, E., Pihlajamäki, J., Charlotte Ling, Froguel, P., Schürmann, A. & Schwenk, R. W., 2017 Jan 1, In : Diabetes. 66, 1, p. 25-35 11 p.

    Research output: Contribution to journalArticle

  6. Hepato-Incretin Function of GLP-1: Novel Concept and Target in Type 1 Diabetes.

    Bo Ahrén, 2015, In : Diabetes. 64, 3, p. 715-717

    Research output: Contribution to journalDebate/Note/Editorial

  7. High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

    Florez, JC., Wiltshire, S., Agapakis, CM., Burtt, NP., de Bakker, PIW., Almgren, P., Bostrom, KB., Tuomi, T., Gaudet, D., Daly, MJ., Hirschhorn, JN., McCarthy, MI., Altshuler, D. & Leif Groop, 2006, In : Diabetes. 55, 1, p. 128-135

    Research output: Contribution to journalArticle

  8. HLA Class I and Genetic Susceptibility to Type 1 Diabetes Results From the Type 1 Diabetes Genetics Consortium

    Noble, J. A., Valdes, A. M., Varney, M. D., Joyce Carlson, Moonsamy, P., Fear, A. L., Lane, J. A., Lavant, E., Rappner, R., Louey, A., Concannon, P., Mychaleckyj, J. C. & Erlich, H. A., 2010, In : Diabetes. 59, 11, p. 2972-2979

    Research output: Contribution to journalArticle

  9. HLA DPA1, DPB1 Alleles and Haplotypes Contribute to the Risk Associated With Type 1 Diabetes Analysis of the Type 1 Diabetes Genetics Consortium Families

    Varney, M. D., Valdes, A. M., Joyce Carlson, Noble, J. A., Tait, B. D., Bonella, P., Lavant, E., Fear, A. L., Louey, A., Moonsamy, P., Mychaleckyj, J. C. & Erlich, H., 2010, In : Diabetes. 59, 8, p. 2055-2062

    Research output: Contribution to journalArticle

  10. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the Type 1 Diabetes Genetics Consortium families

    Erlich, H., Valdes, A. M., Noble, J., Joyce Carlson, Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., Lavant, E., Louey, A. & Moonsamy, P., 2008, In : Diabetes. 57, 4, p. 1084-1092

    Research output: Contribution to journalArticle

  11. Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells

    Hindrik Mulder, Stensson Holst, L., Svensson, H., Eva Degerman, Sundler, F., Bo Ahrén, Rorsman, P. & Cecilia Holm, 1999, In : Diabetes. 48, 1, p. 228-232

    Research output: Contribution to journalArticle

  12. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat

    Kaldunski, M. L., Jia, S., Geoffrey, R., Basken, J., Prosser, S., Kansra, S., Mordes, J. P., Åke Lernmark, Wang, X. & Hessner, M. J., 2010, In : Diabetes. 59, 10, p. 2375-2385 11 p.

    Research output: Contribution to journalArticle

  13. IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies

    Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Doring, A., Lowel, H., Lieb, W., Hengstenberg, C., Rathmann, W. & 25 others, Martin, S., Stephens, J. W., Ireland, H., Mather, H., Miller, G. J., Stringham, H. M., Boehnke, M., Tuomilehto, J., Boeing, H., Mohlig, M., Spranger, J., Pfeiffer, A., Wernstedt, I., Niklason, A., Lopez-Bermejo, A., Fernandez-Real, J-M., Hanson, R. L., Gallart, L., Vendrell, J., Tsiavou, A., Hatziagelaki, E., Humphries, S. E., Wichmann, H. -E., Herder, C. & Illig, T., 2006, In : Diabetes. 55, 10, p. 2915-2921

    Research output: Contribution to journalArticle

  14. Immunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release

    Kanatsuna, T., Baekkeskov, S., A. Lernmark & Ludvigsson, J., 1983 Jan 1, In : Diabetes. 32, 6 I, p. 520-524 5 p.

    Research output: Contribution to journalArticle

  15. Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.

    Dekker Nitert, M., Dayeh, T., Volkov, P., Elgzyri, T., Hall, E., Nilsson, E., Yang, B., Lang, S., Parikh, H., Wessman, Y., Weishaupt, H., Attema, J., Abels, M., Wierup, N., Almgren, P., Jansson, P-A., Rönn, T., Hansson, O., Eriksson, K-F., Groop, L. & 1 others, Charlotte Ling, 2012, In : Diabetes.

    Research output: Contribution to journalArticle

  16. Impact of rs361072 in the Phosphoinositide 3-Kinase p110 beta Gene on Whole-Body Glucose Metabolism and Subunit Protein Expression in Skeletal Muscle

    Ribel-Madsen, R., Poulsen, P., Holmkvist, J., Mortensen, B., Grarup, N., Friedrichsen, M., Jorgensen, T., Lauritzen, T., Wojtaszewski, J. F. P., Pedersen, O., Hansen, T. & Allan Vaag, 2010, In : Diabetes. 59, 4, p. 1108-1112

    Research output: Contribution to journalArticle

  17. Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.

    Huang, X., Vaag, A., Emma A Nilsson, Hansson, M., Bo Ahrén & Leif Groop, 2003, In : Diabetes. 52, 9, p. 2411-2418

    Research output: Contribution to journalArticle

  18. Impaired Tethering and Fusion of GLUT4 Vesicles in Insulin-Resistant Human Adipose Cells

    Lizunov, V. A., Lee, J-P., Skarulis, M. C., Zimmerberg, J., Cushman, S. W. & Karin Stenkula, 2013, In : Diabetes. 62, 9, p. 3114-3119

    Research output: Contribution to journalArticle

  19. Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop

    Greenbaum, C. J., Palmer, J. P., Nagataki, S., Yamaguchi, Y., Molenaar, J. L., Van Beers, W. A. M., Maclaren, N. K., A. Lernmark, Villena, A. A., Barbosa, J., DeBeaufort, C., Becker, D., Becker, F., Betterle, C., Bosi, E., Bottazzo, G. F., Bright, G., Colman, P. & Dawkins, R. L., 1992 Jan 1, In : Diabetes. 41, 12, p. 1570-1574

    Research output: Contribution to journalArticle

  20. Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion

    Collins, S. C., Do, H. W., Hastoy, B., Hugill, A., Adam, J., Chibalina, M. V., Galvanovskis, J., Godazgar, M., Lee, S., Goldsworthy, M., S Albert Salehi, Tarasov, A. I., Anders H. Rosengren, Cox, R. & Rorsman, P., 2016 Jul 1, In : Diabetes. 65, 7, p. 1952-1961 10 p.

    Research output: Contribution to journalArticle

  21. Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

    Abderrahmani, A., Yengo, L., Caiazzo, R., Canouil, M., Cauchi, S., Raverdy, V., Plaisance, V., Pawlowski, V., Lobbens, S., Maillet, J., Rolland, L., Boutry, R., Queniat, G., Kwapich, M., Tenenbaum, M., Bricambert, J., Saussenthaler, S., Anthony, E., Jha, P., Derop, J. & 18 others, Sand, O., Rabearivelo, I., Leloire, A., Pigeyre, M., Daujat-Chavanieu, M., Gerbal-Chaloin, S., Dayeh, T., Lassailly, G., Mathurin, P., Staels, B., Auwerx, J., Schürmann, A., Postic, C., Schafmayer, C., Hampe, J., Bonnefond, A., Pattou, F. & Froguel, P., 2018 Jul 1, In : Diabetes. 67, 7, p. 1310-1321 12 p.

    Research output: Contribution to journalArticle

  22. Increased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria

    Nosadini, R., Velussi, M., Brocco, E., Abaterusso, C., Carraro, A., Piarulli, F., Morgia, G., Satta, A., Faedda, R., Abhyankar, A., Holger Luthman & Tonolo, G., 2006, In : Diabetes. 55, 1, p. 234-239

    Research output: Contribution to journalArticle

  23. Inflammation-sensitive plasma proteins are associated with future weight gain.

    Gunnar Engström, Bo Hedblad, Stavenow, L., Lind, P., Janzon, L. & Lindgärde, F., 2003, In : Diabetes. 52, 8, p. 2097-2101

    Research output: Contribution to journalArticle

  24. Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: a population-based study.

    Gunnar Engström, Stavenow, L., Bo Hedblad, Lind, P., Karl-Fredrik Eriksson, Janzon, L. & Lindgärde, F., 2003, In : Diabetes. 52, 2, p. 442-447

    Research output: Contribution to journalArticle

  25. Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion.

    Hindrik Mulder, Yang, S., Sörhede Winzell, M., Cecilia Holm & Bo Ahrén, 2004, In : Diabetes. 53, 1, p. 122-128

    Research output: Contribution to journalArticle

  26. Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility

    S Albert Salehi, Quader, SS., Grapengiesser, E. & Hellman, B., 2005, In : Diabetes. 54, 7, p. 2126-2131

    Research output: Contribution to journalArticle

  27. Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets

    Travers, M. E., Mackay, D. J. G., Dekker Nitert, M., Morris, A. P., Lindgren, C. M., Berry, A., Johnson, P. R., Hanley, N., Leif Groop, McCarthy, M. I. & Gloyn, A. L., 2013, In : Diabetes. 62, 3, p. 987-992

    Research output: Contribution to journalArticle

  28. Insulin resistance is accompanied by increased fasting glucagon and delayed glucagon suppression in individuals with normal and impaired glucose regulation

    Færch, K., Vistisen, D., Pacini, G., Torekov, S. S., Johansen, N. B., Witte, D. R., Jonsson, A., Pedersen, O., Hansen, T., Lauritzen, T., Jørgensen, M. E., Bo Ahrén & Holst, J. J., 2016 Nov 1, In : Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journalArticle

  29. Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families

    Holm, P., Rydlander, B., Holger Luthman & Kockum, I., 2004, In : Diabetes. 53, 6, p. 1584-1591

    Research output: Contribution to journalArticle

  30. Interferon expression in the pancreases of patients with type I diabetes

    Huang, X., Yuan, J., Goddard, A., Foulis, A., James, R. F. L., Åke Lernmark, Pujol-Borrell, R., Rabinovitch, A., Somoza, N. & Stewart, T. A., 1995 Jan 1, In : Diabetes. 44, 6, p. 658-664

    Research output: Contribution to journalArticle

  31. Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.

    Fuller, J., Kwitek, A. E., Hawkins, T. J., Moralejo, D. H., Lu, W., Tupling, T. D., Macmurray, A. J., Borchardt, G., Hasinoff, M. & Åke Lernmark, 2006, In : Diabetes. 55, p. 3351-3357

    Research output: Contribution to journalArticle

  32. In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse - Pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

    Henquin, JC., Nenquin, M., Stiernet, P. & Bo Ahrén, 2006, In : Diabetes. 55, 2, p. 441-451

    Research output: Contribution to journalArticle

  33. Islet cell and thyrogastric antibodies in 633 consecutive 15- to 34-yr-old patients in the diabetes incidence study in Sweden

    M. Landin-Olsson, Karlsson, F. A., A. Lernmark, Sundkvist, G., Arnqvist, H., Blohme, G., Lithner, F., Littorin, B., Nystrom, L., Rosenqvist, U., Schersten, B., Wibell, L. & Ostman, J., 1992 Jan 1, In : Diabetes. 41, 8, p. 1022-1027

    Research output: Contribution to journalArticle

  34. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

    Cabric, S., Sanchez, J., Lundgren, T., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibell, A., Tufveson, G., Larsson, R., Korsgren, O. & Nilsson, B., 2007, In : Diabetes. 56, 8, p. 2008-2015

    Research output: Contribution to journalArticle

  35. Kinetics-effect relations of insulin-releasing drugs in patients with type 2 diabetes

    Melander, A., 2004, In : Diabetes. 53, Suppl., p. S151-S155

    Research output: Contribution to journalArticle

  36. Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats

    Markholst, H., Klaff, L. J., Klöppel, G., Åke Lernmark, Mordes, J. P. & Palmer, J., 1990 Jan 1, In : Diabetes. 39, 6, p. 720-727 8 p.

    Research output: Contribution to journalArticle

  37. Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment.

    Stenström, G., Anders Gottsäter, Bakhtadze, E., Berger, B. & Sundkvist, G., 2005, In : Diabetes. 54, Suppl 2, p. S68-S72

    Research output: Contribution to journalArticle

  38. Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.

    Hivert, M-F., Christophi, C. A., Paul Franks, Jablonski, K. A., Ehrmann, D. A., Kahn, S. E., Horton, E. S., Pollin, T. I., Mather, K. J., Perreault, L., Barrett-Connor, E., Knowler, W. C. & Florez, J. C., 2016 Feb, In : Diabetes. 65, 2, p. 520-526

    Research output: Contribution to journalArticle

  39. Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

    Olofsson, C., Collins, S., Bengtsson, M., Lena Eliasson, S Albert Salehi, Shimomura, K., Tarasov, A., Cecilia Holm, Ashcroft, F. & Rorsman, P., 2007, In : Diabetes. 56, 7, p. 1888-1897

    Research output: Contribution to journalArticle

  40. Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes

    Mastrolia, V., Flucher, S. M., Obermair, G. J., Drach, M., Hofer, H., Erik Renström, Schwartz, A., Striessnig, J., Flucher, B. E. & Tuluc, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 897-907 11 p.

    Research output: Contribution to journalArticle

  41. MafA and MafB Regulate Genes Critical to beta-Cells in a Unique Temporal Manner

    Isabella Artner, Hang, Y., Mazur, M., Yamamoto, T., Guo, M., Lindner, J., Magnuson, M. A. & Stein, R., 2010, In : Diabetes. 59, 10, p. 2530-2539

    Research output: Contribution to journalArticle

  42. Magnesium deficiency in IDDM related to level of glycosylated hemoglobin

    Sjögren, A., Florén, C-H. & Åke Nilsson, 1986 Apr 1, In : Diabetes. 35, 4, p. 459-463 5 p.

    Research output: Contribution to journalArticle

  43. Mature-onset obesity in interleukin-1 receptor I knockout mice

    Garcia, MC., Wernstedt, I., Berndtsson, A., Enge, M., Bell, M., Hultgren, O., Horn, M., Bo Ahrén, Enerback, S., Ohlsson, C., Wallenius, V. & Jansson, JO., 2006, In : Diabetes. 55, 5, p. 1205-1213

    Research output: Contribution to journalArticle

  44. Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K+ Channel Activity

    Lin, C-W., Yan, F., Shimamura, S., Barg, S. & Shyng, S-L., 2005, In : Diabetes. 54, 10, p. 2852-2858

    Research output: Contribution to journalArticle

  45. Metabolic and underlying causes of diabetes mellitus

    Grodsky, G. M., Anderson, C. E., Coleman, D. L., Craighead, J. E., Gerritsen, G. C., Hansen, C. T., Herberg, L., Howard, C. F., A. Lernmark, Matschinsky, F. M., Rayfield, E., Riley, W. J. & Rossini, A. A., 1982 Dec 4, In : Diabetes. 31, Suppl. 1, p. 45-53 9 p.

    Research output: Contribution to journalArticle

  46. Metabolite profiling of LADA challenges the view of a metabolically distinct subtype

    Al-Majdoub, M., Ali, A., Storm, P., Anders H. Rosengren, Leif Groop & Peter Spégel, 2017 Apr 1, In : Diabetes. 66, 4, p. 806-814 9 p.

    Research output: Contribution to journalArticle

  47. Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression

    Galgani, M., Nugnes, R., Bruzzese, D., Perna, F., De Rosa, V., Procaccini, C., Mozzillo, E., Corrado Cilio, Helena Larsson, Åke Lernmark, La Cava, A., Franzese, A. & Matarese, G., 2013, In : Diabetes. 62, 7, p. 2481-2491

    Research output: Contribution to journalArticle

  48. Microphthalmia transcription factor regulates pancreatic β-cell function

    Mazur, M., Winkler, M., Ganic, E., Colberg, J. K., Johansson, J., Bennet, H., Malin Fex, Nuber, U. & Isabella Artner, 2013, In : Diabetes. 62, 8, p. 2834-2842

    Research output: Contribution to journalArticle

  49. Model-Based Estimates of the Post-Prandial Response to Carbohydrate and Insulin and of the Carbohydrate-to-Insulin Ratio

    Ståhl, F., Rolf Johansson & Renard, E., 2013, In : Diabetes. 62, 7 Supplement 1, p. A217-A217

    Research output: Contribution to journalPublished meeting abstract