Diabetes, 1939-327X

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  1. 2019
  2. Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes

    Better Diabetes Diagnosis (BDD) Study Group, Aydemir, Ö., Noble, J. A., Bailey, J. A., Åke Lernmark, Marsh, P., Agnes Andersson Svärd, Bearoff, F., Blankenhorn, E. P. & Mordes, J. P., 2019 Jul, In : Diabetes. 68, 7, p. 1523-1527 5 p.

    Research output: Contribution to journalArticle

  3. Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes

    Zhao, L. P., Papadopoulos, G. K., Kwok, B., Xu, B., Kong, M., Moustakas, A. K., Bondinas, G. P., Annelie Carlsson, Helena Elding-Larsson, Ludvigsson, J., Marcus, C., Persson, M., Samuelsson, U., Wang, R., Pyo, C-W., Nelson, W. C., Geraghty, D. E. & Åke Lernmark, 2019, In : Diabetes. 68, 8, p. 1692-1704

    Research output: Contribution to journalArticle

  4. Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families

    TEDDY Study Group, Hippich, M., Beyerlein, A., Hagopian, W. A., Krischer, J. P., Vehik, K., Knoop, J., Winker, C., Toppari, J., Åke Lernmark, Rewers, M. J., Steck, A. K., She, J. X., Akolkar, B., Robertson, C. C., Onengut-Gumuscu, S., Rich, S. S., Bonifacio, E. & Ziegler, A. G., 2019, In : Diabetes. 68, 4, p. 847-857 11 p.

    Research output: Contribution to journalArticle

  5. Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease, and hypertension

    Ji, Y., Yiorkas, A. M., Frau, F., Mook-Kanamori, D., Staiger, H., Thomas, E. L., Atabaki-Pasdar, N., Campbell, A., Tyrrell, J., Jones, S. E., Beaumont, R. N., Wood, A. R., Tuke, M. A., Ruth, K. S., Mahajan, A., Murray, A., Freathy, R. M., Weedon, M. N., Hattersley, A. T., Hayward, C. & 11 othersMachann, J., Häring, H. U., Paul Franks, de Mutsert, R., Pearson, E., Stefan, N., Frayling, T. M., Allebrandt, K. V., Bell, J. D., Blakemore, A. I. & Yaghootkar, H., 2019, In : Diabetes. 68, 1, p. 207-219 13 p.

    Research output: Contribution to journalArticle

  6. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

    Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, Pollack, S., Leif Groop, Emma Ahlqvist, Valeriya Lyssenko, Elisabet Agardh & Sobrin, L., 2019, In : Diabetes. 68, 2, p. 441-456 16 p.

    Research output: Contribution to journalArticle

  7. Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

    TEDDY Study Group, Endesfelder, D., zu Castell, W., Bonifacio, E., Rewers, M., Hagopian, W. A., She, J. X., Ake Lernmark, Toppari, J., Vehik, K., Williams, A. J. K., Yu, L., Akolkar, B., Krischer, J. P., Ziegler, A. G. & Achenbach, P., 2019, In : Diabetes. 68, 1, p. 119-130 12 p.

    Research output: Contribution to journalArticle

  8. 2018
  9. Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

    Abderrahmani, A., Yengo, L., Caiazzo, R., Canouil, M., Cauchi, S., Raverdy, V., Plaisance, V., Pawlowski, V., Lobbens, S., Maillet, J., Rolland, L., Boutry, R., Queniat, G., Kwapich, M., Tenenbaum, M., Bricambert, J., Saussenthaler, S., Anthony, E., Jha, P., Derop, J. & 18 othersSand, O., Rabearivelo, I., Leloire, A., Pigeyre, M., Daujat-Chavanieu, M., Gerbal-Chaloin, S., Dayeh, T., Lassailly, G., Mathurin, P., Staels, B., Auwerx, J., Schürmann, A., Postic, C., Schafmayer, C., Hampe, J., Bonnefond, A., Pattou, F. & Froguel, P., 2018 Jul 1, In : Diabetes. 67, 7, p. 1310-1321 12 p.

    Research output: Contribution to journalArticle

  10. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

    van Zuydam, N. R., Emma Ahlqvist, Ladenvall, C., Almgren, P., Christina-Alexandra Schulz, Marju Orho-Melander, Olle Melander, Valeriya Lyssenko, Tuomi, T., Leif C Groop, McCarthy, M. I., Finnish Diabetic Nephropathy Study (FinnDiane), Hong Kong Diabetes Registry Theme-based Research Scheme Project Group, GENIE (Genetics of Nepropathy an International Effort) Consortium, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, SUMMIT Consortium & Jasmina Kravic, 2018 Jul, In : Diabetes. 67, 7, p. 1414-1427

    Research output: Contribution to journalArticle

  11. Circulating fetuin - A and risk of type 2 diabetes: A mendelian randomization analysis

    Kröger, J., Meidtner, K., Stefan, N., Guevara, M., Kerrison, N. D., Ardanaz, E., Aune, D., Boeing, H., Dorronsoro, M., Dow, C., Fagherazzi, G., Franks, P. W., Freisling, H., Gunter, M. J., Huerta, J. M., Kaaks, R., Key, T. J., Khaw, K. T., Krogh, V., Kühn, T. & 23 othersMancini, F. R., Mattiello, A., Peter M. Nilsson, Olsen, A., Overvad, K., Palli, D., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Salamanca-Fernández, E., Sluijs, I., Spijkerman, A. M. W., Tjonneland, A., Tsilidis, K. K., Tumino, R., Van Der Schouw, Y. T., Forouhi, N. G., Sharp, S. J., Langenberg, C., Riboli, E., Schulze, M. B. & Wareham, N. J., 2018 Jun 1, In : Diabetes. 67, 6, p. 1200-1205 6 p.

    Research output: Contribution to journalArticle

  12. Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells

    Alexander Hamilton, Zhang, Q., Albert Salehi, Willems, M., Knudsen, J. G., Ringgaard, A. K., Chapman, C. E., Gonzalez-Alvarez, A., Surdo, N. C., Zaccolo, M., Basco, D., Johnson, P. R. V., Ramracheya, R., Rutter, G. A., Galione, A., Rorsman, P. & Tarasov, A. I., 2018 Jun, In : Diabetes. 67, 6, p. 1128-1139 12 p.

    Research output: Contribution to journalArticle

  13. Glutamine-elicited secretion of glucagon-like peptide 1 is governed by an activated glutamate dehydrogenase

    Andersson, L. E., Liliya Shcherbina, Al-Majdoub, M., Neelanjan Vishnu, Arroyo, C. B., Carrara, J. A., Claes B. Wollheim, Malin Fex, Hindrik Mulder, Nils Wierup & Peter Spégel, 2018 Mar 1, In : Diabetes. 67, 3, p. 372-384 13 p.

    Research output: Contribution to journalArticle

  14. A global overview of precision medicine in type 2 diabetes

    Hugo Fitipaldi, McCarthy, M. I., Florez, J. C. & Paul W. Franks, 2018, In : Diabetes. 67, 10, p. 1911-1922 12 p.

    Research output: Contribution to journalReview article

  15. Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

    Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Åke Lernmark, Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J. X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

    Research output: Contribution to journalArticle

  16. 2017
  17. Nonsuppressed glucagon after glucose challenge as a potential predictor for glucose tolerance

    Wagner, R., Hakaste, L. H., Emma Ahlqvist, Heni, M., Machann, J., Schick, F., Van Obberghen, E., Stefan, N., Gallwitz, B., Tuomi, T., Häring, H. U., Leif Groop & Fritsche, A., 2017 May 1, In : Diabetes. 66, 5, p. 1373-1379 7 p.

    Research output: Contribution to journalArticle

  18. Bariatric surgery enhances splanchnic vascular responses in patients with type 2 diabetes

    Honka, H., Koffert, J., Kauhanen, S., Teuho, J., Hurme, S., Mari, A., Andreas Lindqvist, Nils Wierup, Leif Groop & Nuutila, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 880-885 6 p.

    Research output: Contribution to journalArticle

  19. Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes

    Mastrolia, V., Flucher, S. M., Obermair, G. J., Drach, M., Hofer, H., Erik Renström, Schwartz, A., Striessnig, J., Flucher, B. E. & Tuluc, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 897-907 11 p.

    Research output: Contribution to journalArticle

  20. Metabolite profiling of LADA challenges the view of a metabolically distinct subtype

    Al-Majdoub, M., Ali, A., Storm, P., Anders H. Rosengren, Leif Groop & Peter Spégel, 2017 Apr 1, In : Diabetes. 66, 4, p. 806-814 9 p.

    Research output: Contribution to journalArticle

  21. An Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes May Be Related to HLA-DQ8

    Axel Wester, Skärstrand, H., Alexander Lind, Ramelius, A., Annelie Carlsson, Cedervall, E., Jönsson, B., Sten A Ivarsson, Helena Larsson, Larsson, K., Bengt Lindberg, Neiderud, J., Malin Fex, Törn, C. & Åke Lernmark, 2017 Mar, In : Diabetes. 66, 3, p. 735-740 6 p.

    Research output: Contribution to journalArticle

  22. Differentiation of diabetes by pathophysiology, natural history, and prognosis

    Skyler, J. S., Bakris, G. L., Bonifacio, E., Darsow, T., Eckel, R. H., Leif Groop, Groop, P-H., Handelsman, Y., Insel, R. A., Mathieu, C., McElvaine, A. T., Palmer, J. P., Pugliese, A., Schatz, D. A., Sosenko, J. M., Wilding, J. P. H. & Ratner, R. E., 2017 Feb 1, In : Diabetes. 66, 2, p. 241-255 15 p.

    Research output: Contribution to journalReview article

  23. Functional investigations of HNF1A identify rare variants as risk factors for type 2 diabetes in the general population

    Najmi, L. A., Aukrust, I., Flannick, J., Molnes, J., Burtt, N., Molven, A., Leif Groop, Altshuler, D., Johansson, S., Bjørkhaug, L. & Njølstad, P. R., 2017 Feb 1, In : Diabetes. 66, 2, p. 335-346 12 p.

    Research output: Contribution to journalArticle

  24. Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells

    Takiishi, T., Cook, D. P., Korf, H., Sebastiani, G., Mancarella, F., João Paulo Monteiro Carvalho Mori Cunha, Wasserfall, C., Casares, N., Lasarte, J. J., Steidler, L., Rottiers, P., Dotta, F., Gysemans, C. & Mathieu, C., 2017 Feb 1, In : Diabetes. 66, 2, p. 448-459

    Research output: Contribution to journalArticle

  25. Hepatic DPP4 DNA methylation associates with fatty liver

    Baumeier, C., Saussenthaler, S., Kammel, A., Jähnert, M., Schlüter, L., Hesse, D., Canouil, M., Lobbens, S., Caiazzo, R., Raverdy, V., Pattou, F., Nilsson, E., Pihlajamäki, J., Charlotte Ling, Froguel, P., Schürmann, A. & Schwenk, R. W., 2017 Jan 1, In : Diabetes. 66, 1, p. 25-35 11 p.

    Research output: Contribution to journalArticle

  26. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Almgren, P., Valeriya Lyssenko, Leif Groop, Paul Franks & DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, 2017, In : Diabetes. 66, 11, p. 2888-2902 15 p.

    Research output: Contribution to journalArticle

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