Diabetes, 1939-327X

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  1. 2019
  2. Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes

    Better Diabetes Diagnosis (BDD) Study Group, Aydemir, Ö., Noble, J. A., Bailey, J. A., Åke Lernmark, Marsh, P., Agnes Andersson Svärd, Bearoff, F., Blankenhorn, E. P. & Mordes, J. P., 2019 Jul, In : Diabetes. 68, 7, p. 1523-1527 5 p.

    Research output: Contribution to journalArticle

  3. Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes

    Zhao, L. P., Papadopoulos, G. K., Kwok, B., Xu, B., Kong, M., Moustakas, A. K., Bondinas, G. P., Annelie Carlsson, Helena Elding-Larsson, Ludvigsson, J., Marcus, C., Persson, M., Samuelsson, U., Wang, R., Pyo, C-W., Nelson, W. C., Geraghty, D. E. & Åke Lernmark, 2019, In : Diabetes. 68, 8, p. 1692-1704

    Research output: Contribution to journalArticle

  4. Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families

    TEDDY Study Group, Hippich, M., Beyerlein, A., Hagopian, W. A., Krischer, J. P., Vehik, K., Knoop, J., Winker, C., Toppari, J., Åke Lernmark, Rewers, M. J., Steck, A. K., She, J. X., Akolkar, B., Robertson, C. C., Onengut-Gumuscu, S., Rich, S. S., Bonifacio, E. & Ziegler, A. G., 2019, In : Diabetes. 68, 4, p. 847-857 11 p.

    Research output: Contribution to journalArticle

  5. Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease, and hypertension

    Ji, Y., Yiorkas, A. M., Frau, F., Mook-Kanamori, D., Staiger, H., Thomas, E. L., Atabaki-Pasdar, N., Campbell, A., Tyrrell, J., Jones, S. E., Beaumont, R. N., Wood, A. R., Tuke, M. A., Ruth, K. S., Mahajan, A., Murray, A., Freathy, R. M., Weedon, M. N., Hattersley, A. T., Hayward, C. & 11 othersMachann, J., Häring, H. U., Paul Franks, de Mutsert, R., Pearson, E., Stefan, N., Frayling, T. M., Allebrandt, K. V., Bell, J. D., Blakemore, A. I. & Yaghootkar, H., 2019, In : Diabetes. 68, 1, p. 207-219 13 p.

    Research output: Contribution to journalArticle

  6. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

    Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, Pollack, S., Leif Groop, Emma Ahlqvist, Valeriya Lyssenko, Elisabet Agardh & Sobrin, L., 2019, In : Diabetes. 68, 2, p. 441-456 16 p.

    Research output: Contribution to journalArticle

  7. Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

    TEDDY Study Group, Endesfelder, D., zu Castell, W., Bonifacio, E., Rewers, M., Hagopian, W. A., She, J. X., Ake Lernmark, Toppari, J., Vehik, K., Williams, A. J. K., Yu, L., Akolkar, B., Krischer, J. P., Ziegler, A. G. & Achenbach, P., 2019, In : Diabetes. 68, 1, p. 119-130 12 p.

    Research output: Contribution to journalArticle

  8. 2018
  9. Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

    Abderrahmani, A., Yengo, L., Caiazzo, R., Canouil, M., Cauchi, S., Raverdy, V., Plaisance, V., Pawlowski, V., Lobbens, S., Maillet, J., Rolland, L., Boutry, R., Queniat, G., Kwapich, M., Tenenbaum, M., Bricambert, J., Saussenthaler, S., Anthony, E., Jha, P., Derop, J. & 18 othersSand, O., Rabearivelo, I., Leloire, A., Pigeyre, M., Daujat-Chavanieu, M., Gerbal-Chaloin, S., Dayeh, T., Lassailly, G., Mathurin, P., Staels, B., Auwerx, J., Schürmann, A., Postic, C., Schafmayer, C., Hampe, J., Bonnefond, A., Pattou, F. & Froguel, P., 2018 Jul 1, In : Diabetes. 67, 7, p. 1310-1321 12 p.

    Research output: Contribution to journalArticle

  10. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

    van Zuydam, N. R., Emma Ahlqvist, Ladenvall, C., Almgren, P., Christina-Alexandra Schulz, Marju Orho-Melander, Olle Melander, Valeriya Lyssenko, Tuomi, T., Leif C Groop, McCarthy, M. I., Finnish Diabetic Nephropathy Study (FinnDiane), Hong Kong Diabetes Registry Theme-based Research Scheme Project Group, GENIE (Genetics of Nepropathy an International Effort) Consortium, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, SUMMIT Consortium & Jasmina Kravic, 2018 Jul, In : Diabetes. 67, 7, p. 1414-1427

    Research output: Contribution to journalArticle

  11. Circulating fetuin - A and risk of type 2 diabetes: A mendelian randomization analysis

    Kröger, J., Meidtner, K., Stefan, N., Guevara, M., Kerrison, N. D., Ardanaz, E., Aune, D., Boeing, H., Dorronsoro, M., Dow, C., Fagherazzi, G., Franks, P. W., Freisling, H., Gunter, M. J., Huerta, J. M., Kaaks, R., Key, T. J., Khaw, K. T., Krogh, V., Kühn, T. & 23 othersMancini, F. R., Mattiello, A., Peter M. Nilsson, Olsen, A., Overvad, K., Palli, D., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Salamanca-Fernández, E., Sluijs, I., Spijkerman, A. M. W., Tjonneland, A., Tsilidis, K. K., Tumino, R., Van Der Schouw, Y. T., Forouhi, N. G., Sharp, S. J., Langenberg, C., Riboli, E., Schulze, M. B. & Wareham, N. J., 2018 Jun 1, In : Diabetes. 67, 6, p. 1200-1205 6 p.

    Research output: Contribution to journalArticle

  12. Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells

    Alexander Hamilton, Zhang, Q., Albert Salehi, Willems, M., Knudsen, J. G., Ringgaard, A. K., Chapman, C. E., Gonzalez-Alvarez, A., Surdo, N. C., Zaccolo, M., Basco, D., Johnson, P. R. V., Ramracheya, R., Rutter, G. A., Galione, A., Rorsman, P. & Tarasov, A. I., 2018 Jun, In : Diabetes. 67, 6, p. 1128-1139 12 p.

    Research output: Contribution to journalArticle

  13. Glutamine-elicited secretion of glucagon-like peptide 1 is governed by an activated glutamate dehydrogenase

    Andersson, L. E., Liliya Shcherbina, Al-Majdoub, M., Neelanjan Vishnu, Arroyo, C. B., Carrara, J. A., Claes B. Wollheim, Malin Fex, Hindrik Mulder, Nils Wierup & Peter Spégel, 2018 Mar 1, In : Diabetes. 67, 3, p. 372-384 13 p.

    Research output: Contribution to journalArticle

  14. A global overview of precision medicine in type 2 diabetes

    Hugo Fitipaldi, McCarthy, M. I., Florez, J. C. & Paul W. Franks, 2018, In : Diabetes. 67, 10, p. 1911-1922 12 p.

    Research output: Contribution to journalReview article

  15. Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

    Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Åke Lernmark, Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J. X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

    Research output: Contribution to journalArticle

  16. 2017
  17. Nonsuppressed glucagon after glucose challenge as a potential predictor for glucose tolerance

    Wagner, R., Hakaste, L. H., Emma Ahlqvist, Heni, M., Machann, J., Schick, F., Van Obberghen, E., Stefan, N., Gallwitz, B., Tuomi, T., Häring, H. U., Leif Groop & Fritsche, A., 2017 May 1, In : Diabetes. 66, 5, p. 1373-1379 7 p.

    Research output: Contribution to journalArticle

  18. Bariatric surgery enhances splanchnic vascular responses in patients with type 2 diabetes

    Honka, H., Koffert, J., Kauhanen, S., Teuho, J., Hurme, S., Mari, A., Andreas Lindqvist, Nils Wierup, Leif Groop & Nuutila, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 880-885 6 p.

    Research output: Contribution to journalArticle

  19. Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes

    Mastrolia, V., Flucher, S. M., Obermair, G. J., Drach, M., Hofer, H., Erik Renström, Schwartz, A., Striessnig, J., Flucher, B. E. & Tuluc, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 897-907 11 p.

    Research output: Contribution to journalArticle

  20. Metabolite profiling of LADA challenges the view of a metabolically distinct subtype

    Al-Majdoub, M., Ali, A., Storm, P., Anders H. Rosengren, Leif Groop & Peter Spégel, 2017 Apr 1, In : Diabetes. 66, 4, p. 806-814 9 p.

    Research output: Contribution to journalArticle

  21. An Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes May Be Related to HLA-DQ8

    Axel Wester, Skärstrand, H., Alexander Lind, Ramelius, A., Annelie Carlsson, Cedervall, E., Jönsson, B., Sten A Ivarsson, Helena Larsson, Larsson, K., Bengt Lindberg, Neiderud, J., Malin Fex, Törn, C. & Åke Lernmark, 2017 Mar, In : Diabetes. 66, 3, p. 735-740 6 p.

    Research output: Contribution to journalArticle

  22. Differentiation of diabetes by pathophysiology, natural history, and prognosis

    Skyler, J. S., Bakris, G. L., Bonifacio, E., Darsow, T., Eckel, R. H., Leif Groop, Groop, P-H., Handelsman, Y., Insel, R. A., Mathieu, C., McElvaine, A. T., Palmer, J. P., Pugliese, A., Schatz, D. A., Sosenko, J. M., Wilding, J. P. H. & Ratner, R. E., 2017 Feb 1, In : Diabetes. 66, 2, p. 241-255 15 p.

    Research output: Contribution to journalReview article

  23. Functional investigations of HNF1A identify rare variants as risk factors for type 2 diabetes in the general population

    Najmi, L. A., Aukrust, I., Flannick, J., Molnes, J., Burtt, N., Molven, A., Leif Groop, Altshuler, D., Johansson, S., Bjørkhaug, L. & Njølstad, P. R., 2017 Feb 1, In : Diabetes. 66, 2, p. 335-346 12 p.

    Research output: Contribution to journalArticle

  24. Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells

    Takiishi, T., Cook, D. P., Korf, H., Sebastiani, G., Mancarella, F., João Paulo Monteiro Carvalho Mori Cunha, Wasserfall, C., Casares, N., Lasarte, J. J., Steidler, L., Rottiers, P., Dotta, F., Gysemans, C. & Mathieu, C., 2017 Feb 1, In : Diabetes. 66, 2, p. 448-459

    Research output: Contribution to journalArticle

  25. Hepatic DPP4 DNA methylation associates with fatty liver

    Baumeier, C., Saussenthaler, S., Kammel, A., Jähnert, M., Schlüter, L., Hesse, D., Canouil, M., Lobbens, S., Caiazzo, R., Raverdy, V., Pattou, F., Nilsson, E., Pihlajamäki, J., Charlotte Ling, Froguel, P., Schürmann, A. & Schwenk, R. W., 2017 Jan 1, In : Diabetes. 66, 1, p. 25-35 11 p.

    Research output: Contribution to journalArticle

  26. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Almgren, P., Valeriya Lyssenko, Leif Groop, Paul Franks & DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, 2017, In : Diabetes. 66, 11, p. 2888-2902 15 p.

    Research output: Contribution to journalArticle

  27. Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia

    Ottosson-Laakso, E., Krus, U., Storm, P., Rashmi B Prasad, Nikolay Oskolkov, Emma Ahlqvist, Fadista, J., Ola Hansson, Leif Groop & Petter Vikman, 2017, In : Diabetes. 66, 12, p. 3013-3028

    Research output: Contribution to journalArticle

  28. The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes:A TEDDY Study Report: A TEDDY Study Report

    Krischer, J. P., Liu, X., Åke Lernmark, Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A-G., Akolkar, B. & TEDDY Study Group, 2017, In : Diabetes. 66, 12, p. 3122-3129

    Research output: Contribution to journalArticle

  29. 2016
  30. Insulin resistance is accompanied by increased fasting glucagon and delayed glucagon suppression in individuals with normal and impaired glucose regulation

    Færch, K., Vistisen, D., Pacini, G., Torekov, S. S., Johansen, N. B., Witte, D. R., Jonsson, A., Pedersen, O., Hansen, T., Lauritzen, T., Jørgensen, M. E., Bo Ahrén & Holst, J. J., 2016 Nov 1, In : Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journalArticle

  31. Using genotype-based recall to estimate the effects of amy1 copy number variation in substrate metabolism

    Paul W. Franks & Frida Renström, 2016 Nov 1, In : Diabetes. 65, 11, p. 3240-3242 3 p.

    Research output: Contribution to journalDebate/Note/Editorial

  32. Genome-wide association study of the modified stumvoll insulin sensitivity index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

    Walford, G. A., Gustafsson, S., Rybin, D., Stancáková, A., Chen, H., Liu, C. T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 othersMontasser, M. E., Landenvall, C., Staiger, H., Luan, JA., Frayling, T. M., Weedon, M. N., Xie, W., Morcillo, S., Martínez-Larrad, M. T., Biggs, M. L., Chen, Y. D. I., Corbaton-Anchuelo, A., Færch, K., Gómez-Zumaquero, J. M., Goodarzi, M. O., Kizer, J. R., Koistinen, H. A., Leong, A., Lind, L., Lindgren, C., Machicao, F., Manning, A. K., Martín-Núñez, G. M., Rojo-Martínez, G., Rotter, J. I., Siscovick, D. S., Zmuda, J. M., Zhang, Z., Serrano-Rios, M., Smith, U., Soriguer, F., Hansen, T., JØrgensen, T. J., Linnenberg, A., Pedersen, O., Walker, M., Langenberg, C., Scott, R. A., Wareham, N. J., Fritsche, A., Häring, H. U., Stefan, N., Leif Groop, O'Connell, J. R., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., März, W., Kovacs, P., Stumvoll, M., Psaty, B. M., Kuusisto, J., Laakso, M., Meigs, J. B., Dupuis, J., Ingelsson, E. & Florez, J. C., 2016 Oct 1, In : Diabetes. 65, 10, p. 3200-3211 12 p.

    Research output: Contribution to journalArticle

  33. Partial disruption of lipolysis increases postexercise insulin sensitivity in skeletal muscle despite accumulation of DAG

    Serup, A. K., Alsted, T. J., Jordy, A. BØ., Schjerling, P., Cecilia Holm & Kiens, B., 2016 Oct 1, In : Diabetes. 65, 10, p. 2932-2942 11 p.

    Research output: Contribution to journalArticle

  34. Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The environmental determinants of diabetes in the young study

    Helena Elding Larsson, Vehik, K., Haller, M. J., Liu, X., Akolkar, B., Hagopian, W., Krischer, J., Åke Lernmark, She, J. X., Simell, O., Toppari, J., Ziegler, A. G. & Rewers, M., 2016 Jul 1, In : Diabetes. 65, 7, p. 1988-1995 8 p.

    Research output: Contribution to journalArticle

  35. Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion

    Collins, S. C., Do, H. W., Hastoy, B., Hugill, A., Adam, J., Chibalina, M. V., Galvanovskis, J., Godazgar, M., Lee, S., Goldsworthy, M., S Albert Salehi, Tarasov, A. I., Anders H. Rosengren, Cox, R. & Rorsman, P., 2016 Jul 1, In : Diabetes. 65, 7, p. 1952-1961 10 p.

    Research output: Contribution to journalArticle

  36. Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.

    Hivert, M-F., Christophi, C. A., Paul Franks, Jablonski, K. A., Ehrmann, D. A., Kahn, S. E., Horton, E. S., Pollin, T. I., Mather, K. J., Perreault, L., Barrett-Connor, E., Knowler, W. C. & Florez, J. C., 2016 Feb, In : Diabetes. 65, 2, p. 520-526

    Research output: Contribution to journalArticle

  37. Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

    Berglund, L., Lyssenko, V., Ladenvall, C., Kotova, O., Edsfeldt, A., Pilgaard, K., Alkayyali, S., Brøns, C., Forsblom, C., Jonsson, A., Zetterqvist, A., Nitulescu, M., Ruiz McDavitt, C., Dunér, P., Stancáková, A., Kuusisto, J., Ahlqvist, E., Lajer, M., Tarnow, L., Madsbad, S. & 13 othersRossing, P., Kieffer, T. J., Olle Melander, Marju Orho-Melander, Peter Nilsson, Groop, P-H., Allan Vaag, Lindblad, B., Anders Gottsäter, Laakso, M., Isabel Goncalves, Leif Groop & Maria Gomez, 2016, In : Diabetes. 65, 1, p. 239-254

    Research output: Contribution to journalArticle

  38. Next generation sequencing reveals that HLA-DRB3, -DRB4 and -DRB5 may be associated with islet autoantibodies and risk for childhood type 1 diabetes.

    Zhao, L. P., Shehab Alshiekh, Annelie Carlsson, Helena Larsson, Forsander, G., Sten Ivarsson, Ludvigsson, J., Kockum, I., Marcus, C., Persson, M., Samuelsson, U., Örtqvist, E., Pyo, C-W., Nelson, W. C., Geraghty, D. E. & Åke Lernmark, 2016, In : Diabetes. 65, 3, p. 710-718

    Research output: Contribution to journalArticle

  39. 2015
  40. Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.

    Fall, T., Hägg, S., Ploner, A., Mägi, R., Fischer, K., Draisma, H. H. M., Sarin, A-P., Benyamin, B., Ladenvall, C., Åkerlund, M., Kals, M., Esko, T., Nelson, C. P., Kaakinen, M., Huikari, V., Mangino, M., Meirhaeghe, A., Kristiansson, K., Nuotio, M-L., Kobl, M. & 68 othersGrallert, H., Dehghan, A., Kuningas, M., de Vries, P. S., de Bruijn, R. F. A. G., Willems, S. M., Heikkilä, K., Silventoinen, K., Pietiläinen, K. H., Legry, V., Giedraitis, V., Goumidi, L., Syvänen, A-C., Strauch, K., Koenig, W., Lichtner, P., Herder, C., Palotie, A., Menni, C., Uitterlinden, A. G., Kuulasmaa, K., Havulinna, A. S., Moreno, L. A., Gonzalez-Gross, M., Evans, A., Tregouet, D-A., Yarnell, J. W. G., Virtamo, J., Ferrières, J., Veronesi, G., Perola, M., Arveiler, D., Brambilla, P., Lind, L., Kaprio, J., Hofman, A., Stricker, B. H., van Duijn, C. M., Ikram, M. A., Franco, O. H., Cottel, D., Dallongeville, J., Hall, A. S., Jula, A., Tobin, M. D., Penninx, B. W., Peters, A., Gieger, C., Samani, N. J., Montgomery, G. W., Whitfield, J. B., Martin, N. G., Leif Groop, Spector, T. D., Magnusson, P. K., Amouyel, P., Boomsma, D. I., Peter Nilsson, Järvelin, M-R., Valeriya Lyssenko, Metspalu, A., Strachan, D. P., Salomaa, V., Ripatti, S., Pedersen, N. L., Prokopenko, I., McCarthy, M. I. & Ingelsson, E., 2015, In : Diabetes. 64, 5, p. 1841-1852

    Research output: Contribution to journalArticle

  41. A Mendelian randomization study of circulating uric acid and type 2 diabetes.

    Sluijs, I., Holmes, M. V., van der Schouw, Y. T., Beulens, J. W., Asselbergs, F. W., Huerta, J. M., Palmer, T. M., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Clavel-Chapelon, F., Fagherazzi, G., Franks, P., Gavrila, D., Kaaks, R., Khaw, K. T., Kühn, T., Molina-Montes, E., Mortensen, L. M. & 22 othersPeter Nilsson, Overvad, K., Palli, D., Panico, S., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Schmidt, J. A., Scott, R. A., Sieri, S., Slimani, N., Spijkerman, A. M., Tjonneland, A., Travis Dphil, R. C., Tumino, R., van der A, D. L., Sharp, S. J., Forouhi, N. G., Langenberg, C., Riboli, E. & Wareham, N. J., 2015, In : Diabetes. 64, 8, p. 3028-3036

    Research output: Contribution to journalArticle

  42. Dimethylglycine Deficiency and the Development of Diabetes mellitus.

    Martin Magnusson, Wang, T. J., Clish, C., Gunnar Engström, Peter Nilsson, Gerszten, R. E. & Olle Melander, 2015, In : Diabetes. 64, 8, p. 3010-3016

    Research output: Contribution to journalArticle

  43. Genetic predisposition to weight loss & regain with lifestyle intervention: analyses from the Diabetes Prevention Program & the Look AHEAD randomized controlled trials.

    Papandonatos, G. D., Pan, Q., Pajewski, N. M., Delahanty, L. M., Peter, I., Erar, B., Shafqat Ahmad, Harden, M., Chen, L., Fontanillas, P., Wagenknecht, L. E., Kahn, S. E., Wing, R. R., Jablonski, K. A., Huggins, G. S., Knowler, W. C., Florez, J. C., McCaffery, J. M. & Paul Franks, 2015, In : Diabetes. 64, 12, p. 4312-4321

    Research output: Contribution to journalArticle

  44. Hepato-Incretin Function of GLP-1: Novel Concept and Target in Type 1 Diabetes.

    Bo Ahrén, 2015, In : Diabetes. 64, 3, p. 715-717

    Research output: Contribution to journalDebate/Note/Editorial

  45. Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study.

    Törn, C., Hadley, D., Lee, H-S., Hagopian, W., Åke Lernmark, Simell, O., Rewers, M., Ziegler, A., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W-M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Steck, A. K. & Krischer, J., 2015, In : Diabetes. 64, 5, p. 1818-1829

    Research output: Contribution to journalArticle

  46. The streetlight effect-is there light at the end of the tunnel?

    Åke Lernmark, 2015, In : Diabetes. 64, 4, p. 1105-1107

    Research output: Contribution to journalDebate/Note/Editorial

  47. Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes.

    Fall, T., Xie, W., Poon, W., Yaghootkar, H., Mägi, R., Knowles, J. W., Valeriya Lyssenko, Weedon, M., Frayling, T. M. & Ingelsson, E., 2015, In : Diabetes. 64, 7, p. 2676-2684

    Research output: Contribution to journalArticle

  48. 2014
  49. Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.

    Emma A Nilsson, Jansson, P. A., Alexander Perfilyev, Petr Volkov, Pedersen, M., Svensson, M. K., Poulsen, P., Ribel-Madsen, R., Pedersen, N. L., Almgren, P., Fadista, J., Tina Rönn, Klarlund-Pedersen, B., Scheele, C., Allan Vaag & Charlotte Ling, 2014, In : Diabetes. 63, 9, p. 2962-2976

    Research output: Contribution to journalArticle

  50. Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity.

    Scott, R. A., Fall, T., Pasko, D., Barker, A., Sharp, S. J., Arriola, L., Balkau, B., Barricarte, A., Barroso, I., Boeing, H., Clavel-Chapelon, F., Crowe, F. L., Dekker, J. M., Fagherazzi, G., Ferraninini, E., Forouhi, N. G., Franks, P., Gavrila, D., Giedraitis, V., Grioni, S. & 33 othersLeif Groop, Kaaks, R., Key, T. J., Kühn, T., Lotta, L., Peter Nilsson, Overvad, K., Palli, D., Panico, S., Quirós, J. R., Rolandsson, O., Roswall, N., Sacerdote, C., Sala, N., Sánchez, M-J., Schulze, M. B., Siddiq, A., Slimani, N., Sluijs, I., Spijkerman, A. M., Tjonneland, A., Tumino, R., van der A, D. L., Yaghootkar, H., McCarthy, M. I., Semple, R. K., Riboli, E., Walker, M., Ingelsson, E., Frayling, T. M., Savage, D. B., Langenberg, C. & Wareham, N. J., 2014, In : Diabetes. 63, 12, p. 4378-4387

    Research output: Contribution to journalArticle

  51. Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

    Keildson, S., Fadista, J., Ladenvall, C., Hedman, A. K., Elgzyri, T., Small, K. S., Grundberg, E., Nica, A. C., Glass, D., Richards, J. B., Barrett, A., Nisbet, J., Zheng, H-F., Rönn, T., Ström, K., Eriksson, K-F., Prokopenko, I., Spector, T. D., Dermitzakis, E. T., Deloukas, P. & 6 othersMcCarthy, M. I., Rung, J., Leif Groop, Paul Franks, Lindgren, C. M. & Ola Hansson, 2014, In : Diabetes. 63, 3, p. 1154-1165

    Research output: Contribution to journalArticle

  52. Fibroblast Growth Factor 21 (FGF21) and Glucagon Like-Peptide 1 Contribute to Diabetes Resistance in Glucagon Receptor Deficient Mice.

    Omar, B., Andersen, B., Hald, J., Raun, K., Nishimura, E. & Bo Ahrén, 2014, In : Diabetes. 63, 1, p. 101-110

    Research output: Contribution to journalArticle

  53. Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors.

    Omar, B. & Bo Ahrén, 2014, In : Diabetes. 63, 7, p. 2196-2202

    Research output: Contribution to journalArticle

  54. 2013
  55. Activation of enteroendocrine membrane progesterone receptors promotes incretin secretion and improves glucose tolerance in mice

    Flock, G. B., Cao, X., Marlena Maziarz & Drucker, D. J., 2013 Jan 1, In : Diabetes. 62, 1, p. 283-290 8 p.

    Research output: Contribution to journalArticle

  56. A link between GIP and osteopontin in adipose tissue and insulin resistance.

    Ahlqvist, E., Osmark, P., Kuulasmaa, T., Pilgaard, K., Omar, B., Brøns, C., Kotova, O., Zetterqvist, A., Stancáková, A., Jonsson, A., Hansson, O., Kuusisto, J., Kieffer, T. J., Tuomi, T., Isomaa, B., Madsbad, S., Gomez, M. F., Poulsen, P., Laakso, M., Degerman, E. & 5 othersPihlajamäki, J., Nils Wierup, Allan Vaag, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 6, p. 2088-2094

    Research output: Contribution to journalArticle

  57. Antidiabetic Actions of an Estrogen Receptor beta Selective Agonist

    Alonso-Magdalena, P., Ropero, A. B., Garcia-Arevalo, M., Soriano, S., Quesada, I., Jabar Muhammed, S., S Albert Salehi, Gustafsson, J-A. & Nadal, A., 2013, In : Diabetes. 62, 6, p. 2015-2025

    Research output: Contribution to journalArticle

  58. Decreased cord-blood phospholipids in young age at onset type 1 diabetes.

    Daria La Torre, Seppänen-Laakso, T., Helena Larsson, Hyötyläinen, T., Sten Ivarsson, Åke Lernmark & Oresic, M., 2013, In : Diabetes. 62, 11, p. 3951-3956

    Research output: Contribution to journalArticle

  59. Depleting T cells in newly diagnosed autoimmune (type 1) diabetes--are we getting anywhere?

    Åke Lernmark, 2013, In : Diabetes. 62, 11, p. 3669-3670

    Research output: Contribution to journalDebate/Note/Editorial

  60. Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance

    Ferrannini, E., Natali, A., Camastra, S., Nannipieri, M., Mari, A., Adam, K-P., Milburn, M. V., Kastemmueller, G., Adamski, J., Tuomi, T., Valeriya Lyssenko, Leif Groop & Gall, W. E., 2013, In : Diabetes. 62, 5, p. 1730-1737

    Research output: Contribution to journalArticle

  61. Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.

    Jonsson, A., Ladenvall, C., Ahluwalia, T. S., Jasmina Kravic, Krus, U., Taneera, J., Isomaa, B., Tuomi, T., Erik Renström, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 8, p. 2978-2983

    Research output: Contribution to journalArticle

  62. Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

    Xie, W., Wood, A. R., Lyssenko, V., Weedon, M. N., Knowles, J. W., Alkayyali, S., Assimes, T. L., Quertermous, T., Abbasi, F., Paananen, J., Haering, H., Hansen, T., Pedersen, O., Smith, U., Laakso, M., Dekker, J. M., Nolan, J. J., Groop, L., Ferrannini, E., Adam, K-P. & 3 othersGall, W. E., Frayling, T. M. & Walker, M., 2013, In : Diabetes. 62, 6, p. 2141-2150

    Research output: Contribution to journalArticle

  63. Impaired Tethering and Fusion of GLUT4 Vesicles in Insulin-Resistant Human Adipose Cells

    Lizunov, V. A., Lee, J-P., Skarulis, M. C., Zimmerberg, J., Cushman, S. W. & Karin Stenkula, 2013, In : Diabetes. 62, 9, p. 3114-3119

    Research output: Contribution to journalArticle

  64. Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets

    Travers, M. E., Mackay, D. J. G., Dekker Nitert, M., Morris, A. P., Lindgren, C. M., Berry, A., Johnson, P. R., Hanley, N., Leif Groop, McCarthy, M. I. & Gloyn, A. L., 2013, In : Diabetes. 62, 3, p. 987-992

    Research output: Contribution to journalArticle

  65. Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression

    Galgani, M., Nugnes, R., Bruzzese, D., Perna, F., De Rosa, V., Procaccini, C., Mozzillo, E., Corrado Cilio, Helena Larsson, Åke Lernmark, La Cava, A., Franzese, A. & Matarese, G., 2013, In : Diabetes. 62, 7, p. 2481-2491

    Research output: Contribution to journalArticle

  66. Microphthalmia transcription factor regulates pancreatic β-cell function

    Mazur, M., Winkler, M., Ganic, E., Colberg, J. K., Johansson, J., Bennet, H., Malin Fex, Nuber, U. & Isabella Artner, 2013, In : Diabetes. 62, 8, p. 2834-2842

    Research output: Contribution to journalArticle

  67. Model-Based Estimates of the Post-Prandial Response to Carbohydrate and Insulin and of the Carbohydrate-to-Insulin Ratio

    Ståhl, F., Rolf Johansson & Renard, E., 2013, In : Diabetes. 62, 7 Supplement 1, p. A217-A217

    Research output: Contribution to journalPublished meeting abstract

  68. The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway

    't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schaefer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 othersWillemsen, G., Heine, R. J., Kramer, M. H. H., Holst, J. J., de Koning, E. J. P., Haering, H-U., Pedersen, O., Leif Groop, de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M., 2013, In : Diabetes. 62, 9, p. 3275-3281

    Research output: Contribution to journalArticle

  69. The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human.

    E, K., N, K., R, K., J, W., CM, O., E, W., Dan Holmberg, S, C. & L, S., 2013, In : Diabetes. 62, 2, p. 531-542

    Research output: Contribution to journalArticle

  70. 2012
  71. Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice.

    R, P., P, A., A, G., S, M., XM, Z., S, M., Dan Holmberg & RA, H., 2012, In : Diabetes. 61, 11, p. 2881-2892

    Research output: Contribution to journalArticle

  72. Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.

    Dekker Nitert, M., Dayeh, T., Volkov, P., Elgzyri, T., Hall, E., Nilsson, E., Yang, B., Lang, S., Parikh, H., Wessman, Y., Weishaupt, H., Attema, J., Abels, M., Wierup, N., Almgren, P., Jansson, P-A., Rönn, T., Hansson, O., Eriksson, K-F., Groop, L. & 1 othersCharlotte Ling, 2012, In : Diabetes.

    Research output: Contribution to journalArticle

  73. No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels

    Scott, R. A., Chu, A. Y., Grarup, N., Manning, A. K., Hivert, M-F., Shungin, D., Toenjes, A., Yesupriya, A., Barnes, D., Bouatia-Naji, N., Glazer, N. L., Jackson, A. U., Kutalik, Z., Lagou, V., Marek, D., Rasmussen-Torvik, L. J., Stringham, H. M., Tanaka, T., Aadahl, M., Arking, D. E. & 87 othersBergmann, S., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Brunner, E., Bumpstead, S. J., Brage, S., Carlson, O. D., Chen, H., Chen, Y-D. I., Chines, P. S., Collins, F. S., Couper, D. J., Dennison, E. M., Dowling, N. F., Egan, J. S., Ekelund, U., Erdos, M. R., Forouhi, N. G., Fox, C. S., Goodarzi, M. O., Graessler, J., Gustafsson, S., Hallmans, G., Hansen, T., Hingorani, A., Holloway, J. W., Hu, F. B., Isomaa, B., Jameson, K. A., Johansson, I., Jonsson, A., Jorgensen, T., Kivimaki, M., Kovacs, P., Kumari, M., Kuusisto, J., Laakso, M., Lecoeur, C., Levy-Marchal, C., Li, G., Loos, R. J. F., Valeriya Lyssenko, Marmot, M., Marques-Vidal, P., Morken, M. A., Mueller, G., North, K. E., Pankow, J. S., Payne, F., Prokopenko, I., Psaty, B. M., Frida Renström, Rice, K., Rotter, J. I., Rybin, D., Sandholt, C. H., Sayer, A. A., Shrader, P., Schwarz, P. E. H., Siscovick, D. S., Stancakova, A., Stumvoll, M., Teslovich, T. M., Waeber, G., Williams, G. H., Witte, D. R., Wood, A. R., Xie, W., Boehnke, M., Cooper, C., Ferrucci, L., Froguel, P., Leif Groop, Kao, W. H. L., Vollenweider, P., Walker, M., Watanabe, R. M., Pedersen, O., Meigs, J. B., Ingelsson, E., Barroso, I., Florez, J. C., Paul Franks, Dupuis, J., Wareham, N. J. & Langenberg, C., 2012, In : Diabetes. 61, 5, p. 1291-1296

    Research output: Contribution to journalArticle

  74. Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.

    Rosengren, A., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., Zhang, E., Almgren, P., Ladenvall, C., Axelsson, A., Edlund, A., Pedersen, M. G., Jonsson, A., Ramracheya, R., Tang, Y., Walker, J. N., Barrett, A., Johnson, P. R. V., Lyssenko, V., McCarthy, M. I. & 6 othersLeif Groop, S Albert Salehi, Gloyn, A. L., Erik Renström, Rorsman, P. & Lena Eliasson, 2012, In : Diabetes. 61, 7, p. 1726-1733

    Research output: Contribution to journalArticle

  75. Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study.

    Delli, A., Vaziri Sani, F., Lindblad, B., Helena Larsson, Annelie Carlsson, Forsander, G., Sten Ivarsson, Ludvigsson, J., Kockum, I., Marcus, C., Samuelsson, U., Ortqvist, E., Leif Groop, Bondinas, G. P., Papadopoulos, G. K. & Åke Lernmark, 2012, In : Diabetes. 61, 10, p. 2556-2564

    Research output: Contribution to journalArticle

  76. 2011
  77. FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

    Hertel, J. K., Johansson, S., Emily Sonestedt, Jonsson, A., Lie, R. T., Platou, C. G. P., Peter Nilsson, Rukh, G., Midthjell, K., Hveem, K., Olle Melander, Leif Groop, Valeriya Lyssenko, Molven, A., Marju Orho-Melander & Njolstad, P. R., 2011, In : Diabetes. 60, 5, p. 1637-1644

    Research output: Contribution to journalArticle

  78. Genetic predisposition to long-term non-diabetic deteriorations in glucose homeostasis: ten-year follow-up of the GLACIER Study.

    Renström, F., Shungin, D., Johansson, I., Florez, JC., Hallmans, G., Hu, FB. & Paul Franks, 2011, In : Diabetes. 60, 1, p. 345-54

    Research output: Contribution to journalArticle

  79. Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

    Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Travers, M. E., Bouatia-Naji, N., Dimas, A. S., Nica, A., Wheeler, E., Chen, H., Voight, B. F., Taneera, J., Kanoni, S., Peden, J. F., Turrini, F., Gustafsson, S., Zabena, C. & 83 othersAlmgren, P., Barker, D. J. P., Barnes, D., Dennison, E. M., Eriksson, J. G., Eriksson, P., Eury, E., Folkersen, L., Fox, C. S., Frayling, T. M., Goel, A., Gu, H. F., Horikoshi, M., Isomaa, B., Jackson, A. U., Jameson, K. A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R. J. F., Luan, J., Makrilakis, K., Manning, A. K., Teresa Martinez-Larrad, M., Narisu, N., Mannila, M. N., Ohrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A. A., Sennblad, B., Silveira, A., Stancakova, A., Stirrups, K., Swift, A. J., Syvanen, A-C., Tuomi, T., van 't Hooft, F. M., Walker, M., Weedon, M. N., Xie, W., Zethelius, B., Ongen, H., Malarstig, A., Hopewell, J. C., Saleheen, D., Chambers, J., Parish, S., Danesh, J., Kooner, J., Ostenson, C-G., Lind, L., Cooper, C. C., Serrano-Rios, M., Ferrannini, E., Forsen, T. J., Clarke, R., Franzosi, M. G., Seedorf, U., Watkins, H., Froguel, P., Johnson, P., Deloukas, P., Collins, F. S., Laakso, M., Dermitzakis, E. T., Boehnke, M., McCarthy, M. I., Wareham, N. J., Leif Groop, Pattou, F., Gloyn, A. L., Dedoussis, G. V., Valeriya Lyssenko, Meigs, J. B., Barroso, I., Watanabe, R. M., Ingelsson, E., Langenberg, C., Hamsten, A. & Florez, J. C., 2011, In : Diabetes. 60, 10, p. 2624-2634

    Research output: Contribution to journalArticle

  80. Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

    Lyssenko, V., Eliasson, L., Kotova, O., Pilgaard, K., Wierup, N., Salehi, S. A., Wendt, A., Jonsson, A., De Marinis, Y. Z., Berglund, L., Taneera, J., Balhuizen, A., Hansson, O., Osmark, P., Dunér, P., Brons, C., Stancakova, A., Kuusisto, J., Bugliani, M., Saxena, R. & 19 othersEmma Ahlqvist, Kieffer, T. J., Tuomi, T., Isomaa, B., Olle Melander, Emily Sonestedt, Marju Orho-Melander, Peter Nilsson, Bonetti, S., Bonadonna, R., Miccoli, R., DelPrato, S., Marchetti, P., Madsbad, S., Poulsen, P., Vaag, A., Laakso, M., Maria Gomez & Leif Groop, 2011, In : Diabetes. 60, 9, p. 2424-2433

    Research output: Contribution to journalArticle

  81. Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant A 14-Cohort Meta-analysis

    Kanoni, S., Nettleton, J. A., Hivert, M-F., Ye, Z., van Rooij, F. J. A., Shungin, D., Sonestedt, E., Ngwa, J. S., Wojczynski, M. K., Lemaitre, R. N., Gustafsson, S., Anderson, J. S., Tanaka, T., Hindy, G., Saylor, G., Renstrom, F., Bennett, A. J., van Duijn, C. M., Florez, J. C., Fox, C. S. & 36 othersHofman, A., Hoogeveen, R. C., Houston, D. K., Hu, F. B., Jacques, P. F., Johansson, I., Lind, L., Liu, Y., McKeown, N., Ordovas, J., Pankow, J. S., Sijbrands, E. J. G., Syvanen, A-C., Uitterlinden, A. G., Yannakoulia, M., Zillikens, M. C., Wareham, N. J., Prokopenko, I., Bandinelli, S., Forouhi, N. G., Cupples, L. A., Loos, R. J., Hallmans, G., Dupuis, J., Langenberg, C., Ferrucci, L., Kritchevsky, S. B., McCarthy, M. I., Ingelsson, E., Borecki, I. B., Witteman, J. C. M., Marju Orho-Melander, Siscovick, D. S., Meigs, J. B., Paul Franks & Dedoussis, G. V., 2011, In : Diabetes. 60, 9, p. 2407-2416

    Research output: Contribution to journalArticle

  82. Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

    Hivert, M-F., Jablonski, K. A., Perreault, L., Saxena, R., McAteer, J. B., Paul Franks, Hamman, R. F., Kahn, S. E., Haffner, S., Meigs, J. B., Altshuler, D., Knowler, W. C. & Florez, J. C., 2011, In : Diabetes. 60, 4, p. 1340-1348

    Research output: Contribution to journalArticle

  83. 2010
  84. Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program

    Jablonski, K. A., McAteer, J. B., de Bakker, P. I., Paul Franks, Pollin, T. I., Hanson, R. L., Saxena, R., Fowler, S., Shuldiner, A. R., Knowler, W. C., Altshuler, D. & Florez, J. C., 2010, In : Diabetes. Oct, 59(10), p. 2672-2681

    Research output: Contribution to journalArticle

  85. Diabetes family history: a metabolic storm you should not sit out.

    Paul Franks, 2010, In : Diabetes. 59, p. 2732-2734

    Research output: Contribution to journalArticle

  86. Evaluation of A2BP1 as an Obesity Gene

    Ma, L., Hanson, R. L., Traurig, M. T., Muller, Y. L., Kaur, B. P., Perez, J. M., Meyre, D., Fu, M., Koerner, A., Paul Franks, Kiess, W., Kobes, S., Knowler, W. C., Kovacs, P., Froguel, P., Shuldiner, A. R., Bogardus, C. & Baler, L. J., 2010, In : Diabetes. 59, 11, p. 2837-2845

    Research output: Contribution to journalArticle

  87. GAD Antibody Positivity Predicts Type 2 Diabetes in an Adult Population

    Lundgren, V. M., Isomaa, B., Valeriya Lyssenko, Esa Laurila, Korhonen, P., Leif Groop & Tuomi, T., 2010, In : Diabetes. 59, 2, p. 416-422

    Research output: Contribution to journalArticle

  88. HLA Class I and Genetic Susceptibility to Type 1 Diabetes Results From the Type 1 Diabetes Genetics Consortium

    Noble, J. A., Valdes, A. M., Varney, M. D., Joyce Carlson, Moonsamy, P., Fear, A. L., Lane, J. A., Lavant, E., Rappner, R., Louey, A., Concannon, P., Mychaleckyj, J. C. & Erlich, H. A., 2010, In : Diabetes. 59, 11, p. 2972-2979

    Research output: Contribution to journalArticle

  89. HLA DPA1, DPB1 Alleles and Haplotypes Contribute to the Risk Associated With Type 1 Diabetes Analysis of the Type 1 Diabetes Genetics Consortium Families

    Varney, M. D., Valdes, A. M., Joyce Carlson, Noble, J. A., Tait, B. D., Bonella, P., Lavant, E., Fear, A. L., Louey, A., Moonsamy, P., Mychaleckyj, J. C. & Erlich, H., 2010, In : Diabetes. 59, 8, p. 2055-2062

    Research output: Contribution to journalArticle

  90. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat

    Kaldunski, M. L., Jia, S., Geoffrey, R., Basken, J., Prosser, S., Kansra, S., Mordes, J. P., Åke Lernmark, Wang, X. & Hessner, M. J., 2010, In : Diabetes. 59, 10, p. 2375-2385 11 p.

    Research output: Contribution to journalArticle

  91. Impact of rs361072 in the Phosphoinositide 3-Kinase p110 beta Gene on Whole-Body Glucose Metabolism and Subunit Protein Expression in Skeletal Muscle

    Ribel-Madsen, R., Poulsen, P., Holmkvist, J., Mortensen, B., Grarup, N., Friedrichsen, M., Jorgensen, T., Lauritzen, T., Wojtaszewski, J. F. P., Pedersen, O., Hansen, T. & Allan Vaag, 2010, In : Diabetes. 59, 4, p. 1108-1112

    Research output: Contribution to journalArticle

  92. MafA and MafB Regulate Genes Critical to beta-Cells in a Unique Temporal Manner

    Isabella Artner, Hang, Y., Mazur, M., Yamamoto, T., Guo, M., Lindner, J., Magnuson, M. A. & Stein, R., 2010, In : Diabetes. 59, 10, p. 2530-2539

    Research output: Contribution to journalArticle

  93. The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes

    Bostrom, P., Andersson, L., Vind, B., Haversen, L., Rutberg, M., Wickstrom, Y., Larsson, E., Jansson, P-A., Svensson, M. K., Branemark, R., Charlotte Ling, Beck-Nielsen, H., Boren, J., Hojlund, K. & Olofsson, S-O., 2010, In : Diabetes. 59, 8, p. 1870-1878

    Research output: Contribution to journalArticle

  94. 2009
  95. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

    Jonsson, A., Isomaa, B., Tuomi, T., Taneera, J., S Albert Salehi, Peter Nilsson, Leif Groop & Valeriya Lyssenko, 2009, In : Diabetes. 58, 10, p. 2409-2413

    Research output: Contribution to journalArticle

  96. Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

    Charlotte Ling & Leif Groop, 2009, In : Diabetes. 58, 12, p. 2718-2725

    Research output: Contribution to journalReview article

  97. Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

    Grunnet, L. G., Nilsson, E., Charlotte Ling, Hansen, T., Pedersen, O., Leif Groop, Vaag, A. & Poulsen, P., 2009, In : Diabetes. 58, 10, p. 2402-2408

    Research output: Contribution to journalArticle

  98. Retinol-Binding Protein 4 in Twins Regulatory Mechanisms and Impact of Circulating and Tissue Expression Levels on Insulin Secretion and Action

    Ribel-Madsen, R., Friedrichsen, M., Allan Vaag & Poulsen, P., 2009, In : Diabetes. 58, 1, p. 54-60

    Research output: Contribution to journalArticle

  99. Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes

    Kacerovsky-Bielesz, G., Chmelik, M., Charlotte Ling, Pokan, R., Szendroedi, J., Farukuoye, M., Kacerovsky, M., Schmid, A. I., Gruber, S., Wolzt, M., Moser, E., Pacini, G., Smekal, G., Leif Groop & Roden, M., 2009, In : Diabetes. 58, 6, p. 1333-1341

    Research output: Contribution to journalArticle

  100. 2008
  101. Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

    Orho-Melander, M., Melander, O., Guiducci, C., Perez-Martinez, P., Corella, D., Roos, C., Tewhey, R., Rieder, M. J., Hall, J., Abecasis, G., Tai, E. S., Welch, C., Arnett, D. K., Lyssenko, V., Lindholm, E., Saxena, R., de Bakker, P. I. W., Burtt, N., Voight, B. F., Hirschhorn, J. N. & 21 othersTucker, K. L., Hedner, T., Tuomi, T., Isomaa, B., Karl-Fredrik Eriksson, Taskinen, M-R., Wahlstrand, B., Hughes, T. E., Parnell, L. D., Lai, C-Q., Berglund, G., Peltonen, L., Vartiainen, E., Jousilahti, P., Havulinna, A. S., Salomaa, V., Peter Nilsson, Groop, L., Altshuler, D., Ordovas, J. M. & Kathiresan, S., 2008, In : Diabetes. 57, 11, p. 3112-3121

    Research output: Contribution to journalArticle

  102. Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

    Holmkvist, J., Almgren, P., Lyssenko, V., Lindgren, C. M., Karl-Fredrik Eriksson, Isomaa, B., Tuomi, T., Peter Nilsson & Leif Groop, 2008, In : Diabetes. 57, 6, p. 1738-1744

    Research output: Contribution to journalArticle

  103. Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes

    Cervin, C., Valeriya Lyssenko, Bakhtadze, E., Eero Lindholm, Peter Nilsson, Tuomi, T., Corrado Cilio & Leif Groop, 2008, In : Diabetes. 57, 5, p. 1433-1437

    Research output: Contribution to journalArticle

  104. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the Type 1 Diabetes Genetics Consortium families

    Erlich, H., Valdes, A. M., Noble, J., Joyce Carlson, Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., Lavant, E., Louey, A. & Moonsamy, P., 2008, In : Diabetes. 57, 4, p. 1084-1092

    Research output: Contribution to journalArticle

  105. 2007
  106. Association studies of BMI and type 2 diabetes in the neuropeptide y pathway - A possible role for NPY2R as a candidate gene for type 2 diabetes in men

    Campbell, C. D., Lyon, H. N., Nemesh, J., Drake, J. A., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R. S., Ardlie, K. G., Leif Groop & Hirschhorn, J. N., 2007, In : Diabetes. 56, 5, p. 1460-1467

    Research output: Contribution to journalArticle

  107. Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes

    Winckler, W., Weedon, M. N., Graham, R. R., McCarrolll, S. A., Purcell, S., Almgren, P., Tuomi, T., Gaudet, D., Kristina Bengtsson Boström, Walker, M., Hitman, G., Hattersley, A. T., McCarthy, M. I., Ardlie, K. G., Hirschhorn, J. N., Daly, M. J., Frayling, T. M., Groop, L. & Altshuler, D., 2007, In : Diabetes. 56, 3, p. 685-693

    Research output: Contribution to journalArticle

  108. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

    Cabric, S., Sanchez, J., Lundgren, T., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibell, A., Tufveson, G., Larsson, R., Korsgren, O. & Nilsson, B., 2007, In : Diabetes. 56, 8, p. 2008-2015

    Research output: Contribution to journalArticle

  109. Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

    Olofsson, C., Collins, S., Bengtsson, M., Lena Eliasson, S Albert Salehi, Shimomura, K., Tarasov, A., Cecilia Holm, Ashcroft, F. & Rorsman, P., 2007, In : Diabetes. 56, 7, p. 1888-1897

    Research output: Contribution to journalArticle

  110. 2006