Journal of Experimental Medicine, 1540-9538

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  1. 2021
  2. Platelets instruct T reg cells and macrophages in the resolution of lung inflammation

    Rick Kapur & John W. Semple, 2021 May 24, In: Journal of Experimental Medicine. 218, 7, e20210754.

    Research output: Contribution to journalDebate/Note/Editorial

  3. The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude

    Zhong Yin Li, Rosemary E. Morman, Emma Hegermiller, Mengxi Sun, Elizabeth T. Bartom, Mark Maienschein-Cline, Mikael Sigvardsson & Barbara L. Kee, 2021, In: Journal of Experimental Medicine. 218, 6, e20202032.

    Research output: Contribution to journalArticle

  4. 2020
  5. Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome

    Yin Huai Chen, Giedre Grigelioniene, Phillip T. Newton, Jacob Gullander, Maria Elfving, Anna Hammarsjö, Dominyka Batkovskyte, Hessa S. Alsaif, Wesam I.Y. Kurdi, Firdous Abdulwahab, Veerabahu Shanmugasundaram, Luke Devey, Séverine Bacrot, Jana Brodszki, Celine Huber, Ben Hamel, David Gisselsson, Nikos Papadogiannakis, Katarina Jedrycha, Barbara Gürtl-Lackner & 7 others, Andrei S. Chagin, Gen Nishimura, Dominik Aschenbrenner, Fowzan S. Alkuraya, Arian Laurence, Valérie Cormier-Daire & Holm H. Uhlig, 2020, In: The Journal of experimental medicine. 217, 3, e20191306.

    Research output: Contribution to journalArticle

  6. Continuous mitotic activity of primitive hematopoietic stem cells in adult mice

    Mina N.F. Morcos, Thomas Zerjatke, Ingmar Glauche, Clara M. Munz, Yan Ge, Andreas Petzold, Susanne Reinhardt, Andreas Dahl, Natasha S. Anstee, Ruzhica Bogeska, Michael D. Milsom, Petter Säwén, Haixia Wan, David Bryder, Axel Roers & Alexander Gerbaulet, 2020, In: Journal of Experimental Medicine. 217, 6, e20191284.

    Research output: Contribution to journalArticle

  7. 2019
  8. Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons

    Alex Bersellini Farinotti, Gustaf Wigerblad, Diana Nascimento, Duygu B Bas, Carlos Morado Urbina, Kutty Selva Nandakumar, Katalin Sandor, Bingze Xu, Sally Abdelmoaty, Matthew A Hunt, Kristina Ängeby Möller, Azar Baharpoor, Jon Sinclair, Kent Jardemark, Johanna T Lanner, Ia Khmaladze, Lars E Borm, Lu Zhang, Fredrik Wermeling, Mark S Cragg & 11 others, Johan Lengqvist, Anne-Julie Chabot-Doré, Luda Diatchenko, Inna Belfer, Mattias Collin, Kim Kultima, Birgitta Heyman, Juan Miguel Jimenez-Andrade, Simone Codeluppi, Rikard Holmdahl & Camilla I Svensson, 2019, In: Journal of Experimental Medicine. 216, 8, p. 1904-1924

    Research output: Contribution to journalArticle

  9. 2018
  10. Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis

    Christina T Jensen, Josefine Åhsberg, Mikael N E Sommarin, Tobias Strid, Rajesh Somasundaram, Kazuki Okuyama, Jonas Ungerbäck, Jussi Kupari, Matti S Airaksinen, Stefan Lang, David Bryder, Shamit Soneji, Göran Karlsson & Mikael Sigvardsson, 2018 Jul 2, In: Journal of Experimental Medicine. 215, 7, p. 1947-1963 17 p.

    Research output: Contribution to journalArticle

  11. 2017
  12. TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA

    Christian Lood, Sabine Arve, Jeffrey Ledbetter & Keith B Elkon, 2017 Jun 12, In: Journal of Experimental Medicine. 214, 7, p. 2103-2119 17 p.

    Research output: Contribution to journalArticle

  13. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

    Hoeke A. Baarsma, Wioletta Skronska-Wasek, Kathrin Mutze, Florian Ciolek, Darcy E. Wagner, Gerrit John-Schuster, Katharina Heinzelmann, Andreas Günther, Ken R. Bracke, Maylis Dagouassat, Jorge Boczkowski, Guy Brusselle, Ron Smits, Oliver Eickelberg, Ali Oe. Yildirim & Melanie Königshoff, 2017, In: Journal of Experimental Medicine. 214, 1, p. 143-163 21 p.

    Research output: Contribution to journalArticle

  14. 2015
  15. Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.

    Larry Mansouri, Lesley-Ann Sutton, Viktor Ljungström, Sina Bondza, Linda Arngården, Sujata Bhoi, Jimmy Larsson, Diego Cortese, Antonia Kalushkova, Karla Plevova, Emma Young, Rebeqa Gunnarsson, Elin Falk-Sörqvist, Peter Lönn, Alice F Muggen, Xiao-Jie Yan, Birgitta Sander, Gunilla Enblad, Karin E Smedby, Gunnar Juliusson & 14 others, Chrysoula Belessi, Johan Rung, Nicholas Chiorazzi, Jonathan C Strefford, Anton W Langerak, Sarka Pospisilova, Frederic Davi, Mats Hellström, Helena Jernberg-Wiklund, Paolo Ghia, Ola Söderberg, Kostas Stamatopoulos, Mats Nilsson & Richard Rosenquist, 2015, In: Journal of Experimental Medicine. 212, 6, p. 833-843

    Research output: Contribution to journalArticle

  16. 2014
  17. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

    Marcus Järås, Peter G. Miller, Lisa P. Chu, Rishi V. Puram, Emma C. Fink, Rebekka K. Schneider, Fatima Al-Shahrour, Pablo Peña, L. Jordan Breyfogle, Kimberly A. Hartwell, Marie E. McConkey, Glenn S. Cowley, David E. Root, Michael G. Kharas, Ann Mullally & Benjamin L. Ebert, 2014, In: Journal of Experimental Medicine. 211, 4, p. 605-612

    Research output: Contribution to journalArticle

  18. Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo.

    Derek K Chu, Rodrigo Jimenez-Saiz, Christopher P Verschoor, Tina D Walker, Susanna Goncharova, Alba Llop-Guevara, Pamela Shen, Melissa E Gordon, Nicole G Barra, Jennifer D Bassett, Joshua Kong, Ramzi Fattouh, Kathy D McCoy, Dawn M Bowdish, Jonas Erjefält, Oliver Pabst, Alison A Humbles, Roland Kolbeck, Susan Waserman & Manel Jordana, 2014, In: Journal of Experimental Medicine. 211, 8, p. 1657-1672

    Research output: Contribution to journalArticle

  19. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus

    Syed Raza Ali, Jerry J. Fong, Aaron F. Carlin, Tamara D. Busch, Rebecka Linden, Takashi Angata, Thomas Areschoug, Mana Parast, Nissi Varki, Jeffrey Murray, Victor Nizet & Ajit Varki, 2014, In: Journal of Experimental Medicine. 211, 6, p. 1231-1242

    Research output: Contribution to journalArticle

  20. 2013
  21. The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response

    Jin-Shu He, Michael Meyer-Hermann, Deng Xiangying, Lim Yok Zuan, Leigh Ann Jones, Lakshmi Ramakrishna, Victor C de Vries, Jayashree Dolpady, Hoi Aina, Sabrina Joseph, Sriram Narayanan, Sharrada Subramaniam, Manoj Puthia, Glenn Wong, Huizhong Xiong, Michael Poidinger, Joseph F Urban, Juan J Lafaille & Maria A Curotto de Lafaille, 2013 Nov 18, In: Journal of Experimental Medicine. 210, 12, p. 2755-2771

    Research output: Contribution to journalArticle

  22. Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

    Charlotte Anderberg, Sara I. Cunha, Zhenhua Zhai, Eliane Cortez, Evangelia Pardali, Jill R. Johnson, Marcela Franco, Marta Paez-Ribes, Ross Cordiner, Jonas Fuxe, Bengt R. Johansson, Marie-Jose Goumans, Oriol Casanovas, Peter ten Dijke, Helen M. Arthur & Kristian Pietras, 2013, In: Journal of Experimental Medicine. 210, 3, p. 563-579

    Research output: Contribution to journalArticle

  23. 2012
  24. Antibody orientation at bacterial surfaces is related to invasive infection.

    Pontus Nordenfelt, Sofia Waldemarson, Adam Linder, Matthias Mörgelin, Christofer Karlsson, Johan Malmström & Lars Björck, 2012, In: Journal of Experimental Medicine. 209, 13, p. 2367-2381

    Research output: Contribution to journalArticle

  25. Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

    Anna Mansour, Grazia Abou-Ezzi, Ewa Sitnicka Quinn, Sten Eirik W Jacobsen, Abdelilah Wakkach & Claudine Blin-Wakkach, 2012, In: Journal of Experimental Medicine. 209, 3, p. 537-549

    Research output: Contribution to journalArticle

  26. 2011
  27. Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors.

    Kees-Jan Pronk, Ole Petter Veiby, David Bryder & Sten Eirik W Jacobsen, 2011, In: Journal of Experimental Medicine. 208, 8, p. 1563-1570

    Research output: Contribution to journalArticle

  28. 2009
  29. Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

    Ramin Massoumi, Silke Kuphal, Claus Hellerbrand, Bodo Haas, Peter Wild, Thilo Spruss, Alexander Pfeifer, Reinhard Faessler & Anja K. Bosserhoff, 2009, In: Journal of Experimental Medicine. 206, 1, p. 221-232

    Research output: Contribution to journalArticle

  30. Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5

    Aaron F. Carlin, Yung-Chi Chang, Thomas Areschoug, Gunnar Lindahl, Nancy Hurtado-Ziola, Charles C. King, Ajit Varki & Victor Nizet, 2009, In: Journal of Experimental Medicine. 206, 8, p. 1691-1699

    Research output: Contribution to journalArticle

  31. Intestinal CD103(+), but not CX3CR1(+), antigen sampling cells migrate in lymph and serve classical dendritic cell functions

    Olga Schulz, Elin Jaensson Gyllenbäck, Emma Persson, Xiaosun Liu, Tim Worbs, William Agace & Oliver Pabst, 2009, In: Journal of Experimental Medicine. 206, 13, p. 3101-3114

    Research output: Contribution to journalArticle

  32. Niche recycling through division-independent egress of hematopoietic stem cells

    Deepta Bhattacharya, Agnieszka Czechowicz, A. G. Lisa Ooi, Derrick J. Rossi, David Bryder & Irving L. Weissman, 2009, In: Journal of Experimental Medicine. 206, 12, p. 2837-2850

    Research output: Contribution to journalArticle

  33. Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.

    Hüseyin Uysal, Robert Bockermann, Nandakumar Kutty Selva, Bettina Sehnert, Estelle Bajtner, Ake Engström, Guy Serre, Harald Burkhardt, Marjolein Thunnissen & Rikard Holmdahl, 2009, In: Journal of Experimental Medicine. 206, 2, p. 449-462

    Research output: Contribution to journalArticle

  34. 2008
  35. A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.

    Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet, Anna Magnusson-Lind, Ben Woodman, Christian Landles, Mahmoud A Pouladi, Michael R Hayden, Azadeh Khalili-Shirazi, Mark W Lowdell, Patrik Brundin, Gillian P Bates, Blair R Leavitt & 2 others, Thomas Möller & Sarah J Tabrizi, 2008, In: Journal of Experimental Medicine. 205, p. 1869-1877

    Research output: Contribution to journalArticle

  36. Small intestinal CD103(+) dendritic cells display unique functional properties that are conserved between mice and humans

    Elin Jaensson Gyllenbäck, Heli Uronen-Hansson, Oliver Pabst, Bertus Eksteen, Jiong Tian, Janine L. Coombes, Pia-Lena Berg, Thomas Davidsson, Fiona Powrie, Bengt Johansson Lindbom & William Agace, 2008, In: Journal of Experimental Medicine. 205, 9, p. 2139-2149

    Research output: Contribution to journalArticle

  37. 2007
  38. Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

    Marta Serafini, Scott J Dylla, Masayuki Oki, Yves Heremans, Jakub Tolar, Yuehua Jiang, Shannon M Buckley, Beatriz Pelacho, Terry C Burns, Sarah Frommer, Derrick J Rossi, David Bryder, Angela Panoskaltsis-Mortari & Matt O'Shaughnessy, 2007, In: Journal of Experimental Medicine. 204, 1, p. 129-139

    Research output: Contribution to journalArticle

  39. Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD

    Nadine Hovelmeyer, F Thomas Wunderlich, Ramin Massoumi, Charlotte G Jakobsen, Jian Song, Marcus A Worns, Carsten Merkwirth, Andrew Kovalenko, Monique Aumailley, Dennis Strand, Jens C Bruning, Peter R Galle, David Wallach & Reinhard Fässler, 2007, In: Journal of Experimental Medicine. 204, 11, p. 2615-2627

    Research output: Contribution to journalArticle

  40. Smad4 is critical for self-renewal of hematopoietic stem cells.

    Göran Karlsson, Ulrika Blank Savukinas, Jennifer Moody, Mats Ehinger, Sofie Singbrant, Chu-Xia Deng & Stefan Karlsson, 2007, In: Journal of Experimental Medicine. 204, 3, p. 467-474

    Research output: Contribution to journalArticle

  41. 2006
  42. IL-7 promotes T cell proliferation through destabilization of p27Kip1

    Qing Li Wen, Qiong Jiang, Eiman Aleem, Philipp Kaldis, Annette R. Khaled & Scott K. Durum, 2006 Mar 20, In: Journal of Experimental Medicine. 203, 3, p. 573-582

    Research output: Contribution to journalArticle

  43. Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis.

    Smriti Agrawal, Per Anderson, Madeleine Durbeej-Hjalt, Nico van Rooijen, Fredrik Ivars, Ghislain Opdenakker & Lydia Sorokin, 2006, In: Journal of Experimental Medicine. 203, 4, p. 1007-1019

    Research output: Contribution to journalArticle

  44. Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium

    Eugen Kolossov, Toktam Bostani, Wilhelm Roell, Martin Breitbach, Frank Pillekamp, Jens Nygren, Philipp Sasse, Olga Rubenchik, Jochen W. U. Fries, Daniela Wenzel, Caroline Geisen, Ying Xia, Zhongju Lu, Yaqi Duan, Ralf Kettenhofen, Stefan Jovinge, Wilhelm Bloch, Heribert Bohlen, Armin Welz, Juergen Hescheler & 2 others, Sten Eirik W Jacobsen & Bernd K. Fleischmann, 2006, In: Journal of Experimental Medicine. 203, 10, p. 2315-2327

    Research output: Contribution to journalArticle

  45. Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning

    Deepta Bhattacharya, Derrick J Rossi, David Bryder & Irving L Weissman, 2006, In: Journal of Experimental Medicine. 203, 1, p. 73-85

    Research output: Contribution to journalArticle

  46. 2005
  47. C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation.

    Leendert Trouw, Sara Nilsson, Isabel Goncalves, Göran Landberg & Anna Blom, 2005, In: Journal of Experimental Medicine. 201, 12, p. 1937-1948

    Research output: Contribution to journalArticle

  48. Essential role for CD103 in the T cell-mediated regulation of experimental colitis

    O Annacker, JL Coombes, V Malmstrom, HH Uhlig, T Bourne, Bengt Johansson Lindbom, William Agace, CM Parker & F Powrie, 2005, In: Journal of Experimental Medicine. 202, 8, p. 1051-1061

    Research output: Contribution to journalArticle

  49. Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing.

    Bengt Johansson Lindbom, Marcus Svensson Frej, Oliver Pabst, Caroline Palmqvist, Gabriel Marquez, Reinhold Förster & William Agace, 2005, In: Journal of Experimental Medicine. 202, 8, p. 1063-1073

    Research output: Contribution to journalArticle

  50. Importance of integrin LFA-1 deactivation for the generation of immune responses

    Monika Semmrich, Andrew Smith, Carolin Feterowski, Sandra Beer, Britta Engelhardt, Dirk H Busch, Bernadett Bartsch, Melanie Laschinger, Nancy Hogg, Klaus Pfeffer & Bernhard Holzmann, 2005, In: Journal of Experimental Medicine. 201, 12, p. 1987-1998

    Research output: Contribution to journalArticle

  51. Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage

    BT Porse, David Bryder, K Theilgaard-Monch, MS Hasemann, Kristina Anderson, I Damgaard, Sten Eirik W Jacobsen & C Nerlov, 2005, In: Journal of Experimental Medicine. 202, 1, p. 85-96

    Research output: Contribution to journalArticle

  52. 2004
  53. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

    A Jahng, I Maricic, C Aguilera, Susanna Cardell, RC Halder & V Kumar, 2004, In: Journal of Experimental Medicine. 199, 7, p. 947-957

    Research output: Contribution to journalArticle

  54. 2003
  55. Complementary Signaling through flt3 and Interleukin-7 Receptor {alpha} Is Indispensable for Fetal and Adult B Cell Genesis.

    Ewa Sitnicka Quinn, Cord Brakebusch, Inga-Lill Martensson, Marcus Svensson Frej, William Agace, Mikael Sigvardsson, Natalija Buza-Vidas, David Bryder, Corrado M Cilio, Henrik Ahlenius, Eugene Maraskovsky, Jacques J. Peschon & Sten Eirik W. Jacobsen, 2003, In: Journal of Experimental Medicine. 198, 10, p. 1495-1506

    Research output: Contribution to journalArticle

  56. Selective Generation of Gut Tropic T Cells in Gut-associated Lymphoid Tissue (GALT): Requirement for GALT Dendritic Cells and Adjuvant.

    Bengt Johansson Lindbom, Marcus Svensson Frej, Marc-Andre Wurbel, Bernard Malissen, Gabriel Marquez & William Agace, 2003, In: Journal of Experimental Medicine. 198, 6, p. 963-969

    Research output: Contribution to journalArticle

  57. 2001
  58. Binding of C4b-binding protein: A molecular mechanism of serum resistance of Neisseria gonorrhoeae

    Sanjay Ram, Meabh Cullinane, Anna Blom, Sunita Gulati, Daniel P. McQuillen, Brian G. Monks, Catherine O'Connell, Ryan Boden, Christopher Elkins, Michael K. Pangburn, Björn Dahlbäck & Peter A. Rice, 2001, In: Journal of Experimental Medicine. 193, 3, p. 281-295

    Research output: Contribution to journalArticle

  59. Joining chain-expressing and -nonexpressing B cell populations in the mouse

    Lena Erlandsson, Peter Akerblad, C Vingsbo-Lundberg, Eva Källberg, Nils Lycke & Tomas Leanderson, 2001, In: Journal of Experimental Medicine. 194, 5, p. 557-570

    Research output: Contribution to journalArticle

  60. Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation

    David Bryder, Veslemøy Ramsfjell, Ingunn Dybedal, Kim Theilgaard-Monch, Carl-Magnus Högerkorp, Jörgen Adolfsson, Ole Johan Borge & Sten Eirik W Jacobsen, 2001, In: Journal of Experimental Medicine. 194, 7, p. 941-952

    Research output: Contribution to journalArticle

  61. 2000
  62. Signaling via β2 integrins triggers neutrophil-dependent alteration in endothelial barrier function

    Narinder Gautam, Heiko Herwald, Per Hedqvist & Lennart Lindbom, 2000 Jun 5, In: Journal of Experimental Medicine. 191, 11, p. 1829-1839

    Research output: Contribution to journalArticle

  63. Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells.

    Suling Li, Shangwu Chen, X. Xu, Anette Sundstedt, Kajsa Paulsson, Per andersson, Stefan Karlsson, Hans Olov Sjögren & Ping Wang, 2000 Mar, In: Journal of Experimental Medicine. 191, 6, p. 985-994

    Research output: Contribution to journalArticle

  64. Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart

    Björn Frendeus, Gabriela Godaly, Long Hang, Diana Karpman, Ann-Charlotte Lundstedt & Catharina Svanborg, 2000, In: Journal of Experimental Medicine. 192, 6, p. 881-890

    Research output: Contribution to journalArticle

  65. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity

    E J Kunkel, J J Campbell, G Haraldsen, J Pan, J Boisvert, A I Roberts, E C Ebert, M A Vierra, S B Goodman, M C Genovese, A J Wardlaw, H B Greenberg, C M Parker, E C Butcher, D P Andrew & William Agace, 2000, In: Journal of Experimental Medicine. 192, 5, p. 761-768

    Research output: Contribution to journalArticle

  66. Severe lung lesions caused by Salmonella are prevented by inhibition of the contact system

    Kristin Persson, Matthias Mörgelin, L Lindbom, Per Alm, Lars Björck & Heiko Herwald, 2000, In: Journal of Experimental Medicine. 192, 10, p. 1415-1424

    Research output: Contribution to journalArticle

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