Nature Medicine, 1546-170X

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  1. 2019
  2. Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease

    TRANSEURO consortium, Barker, R. A., Farrell, K., Guzman, N. V., He, X., Lazic, S. E., Moore, S., Morris, R., Tyers, P., Wijeyekoon, R., Daft, D., Hewitt, S., Dayal, V., Foltynie, T., Kefalopoulou, Z., Mahlknecht, P., Lao-Kaim, N. P., Piccini, P., Bjartmarz, H., Björklund, A. & 13 othersOlle Lindvall, Jenny Nelander-Wahlestedt, Malin Parmar, Gesine Paul, Hakan Widner, Church, A., Dunnett, S., Peall, K., Rosser, A., Gurruchaga, J. M., Palfi, S., Piroth, T. & Winkler, C., 2019 Jul, In : Nature Medicine. 25, p. 1045–1053 9 p.

    Research output: Contribution to journalArticle

  3. Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

    Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L. P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A. M., Manghi, P., Gandini, S., Serrano, D. & 15 othersMizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C. M., Brenner, H., Arumugam, M., Bork, P. & Zeller, G., 2019 Apr, In : Nature Medicine. 25, 4, p. 679-689 11 p.

    Research output: Contribution to journalArticle

  4. 2018
  5. Fetal gene therapy for neurodegenerative disease of infants

    Massaro, G., Mattar, C. N. Z., Wong, A. M. S., Sirka, E., Buckley, S. M. K., Herbert, B. R., Karlsson, S., Perocheau, D. P., Burke, D., Heales, S., Richard-Londt, A., Brandner, S., Huebecker, M., Priestman, D. A., Platt, F. M., Mills, K., Biswas, A., Cooper, J. D., Chan, J. K. Y., Cheng, S. H. & 2 othersWaddington, S. N. & Rahim, A. A., 2018 Sep, In : Nature Medicine. 24, 9, p. 1317-1323

    Research output: Contribution to journalLetter

  6. Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling

    Roswall, P., Bocci, M., Bartoschek, M., Li, H., Kristiansen, G., Jansson, S., Lehn, S., Sjölund, J., Reid, S., Larsson, C., Eriksson, P., Anderberg, C., Cortez, E., Saal, L. H., Orsmark-Pietras, C., Cordero, E., Haller, B. K., Häkkinen, J., Burvenich, I. J. G., Lim, E. & 7 othersOrimo, A., Mattias Höglund, Lisa Rydén, Moch, H., Scott, A. M., Eriksson, U. & Kristian Pietras, 2018 Mar 12, In : Nature Medicine. 24, p. 463–473

    Research output: Contribution to journalArticle

  7. Genetic characterization of amyloid-β and tau network spread

    Rik Ossenkoppele & Oskar Hansson, 2018, In : Nature Medicine. 24, p. 1790–1792

    Research output: Contribution to journalArticle

  8. 2017
  9. ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix

    Mayorca-guiliani, A. E., Chris Madsen, Cox, T. R., Horton, E. R., Venning, F. A. & Erler, J. T., 2017 Jul, In : Nature Medicine. 23, 7, p. 890-898

    Research output: Contribution to journalArticle

  10. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

    Davies, H. R., Glodzik, D., Morganella, S., Yates, L. R., Staaf, J., Zou, X., Ramakrishna, M., Martin, S., Boyault, S., Sieuwerts, A. M., Simpson, P. T., King, T. A., Raine, K., Eyfjord, J. E., Kong, G., Borg, Å., Birney, E., Stunnenberg, H. G., van de Vijver, M. J., Børresen-Dale, A-L. & 13 othersMartens, J. W. M., Span, P. N., Lakhani, S. R., Vincent-Salomon, A., Sotiriou, C., Tutt, A., Thompson, A. M., Van Laere, S., Richardson, A. L., Viari, A., Campbell, P. J., Stratton, M. R. & Nik-Zainal, S., 2017 Apr, In : Nature Medicine. 23, 4, p. 517-525 9 p.

    Research output: Contribution to journalArticle

  11. 2015
  12. RIFINs are adhesins implicated in severe Plasmodium falciparum malaria.

    Goel, S., Palmkvist, M., Moll, K., Joannin, N., Lara, P., R Akhouri, R., Moradi, N., Öjemalm, K., Westman, M., Angeletti, D., Kjellin, H., Lehtiö, J., Blixt, O., Ideström, L., Gahmberg, C. G., Storry, J., Hult, A., Olsson, M. L., von Heijne, G., Nilsson, I. & 1 othersWahlgren, M., 2015, In : Nature Medicine. 21, 4, p. 314-317

    Research output: Contribution to journalArticle

  13. 2014
  14. FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS

    Liu, Y., Robert Carlsson, Comabella, M., Wang, J. Y., Kosicki, M., Carrion, B., Hasan, M., Wu, X., Montalban, X., Dziegiel, M. H., Sellebjerg, F., Sørensen, P. S., Helin, K. & Issazadeh-Navikas, S., 2014 Jan 1, In : Nature Medicine. 20, 3, p. 272-282 11 p.

    Research output: Contribution to journalArticle

  15. Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures.

    Movérare-Skrtic, S., Henning, P., Liu, X., Nagano, K., Saito, H., Börjesson, A. E., Sjögren, K., Windahl, S. H., Farman, H., Kindlund, B., Engdahl, C., Koskela, A., Zhang, F-P., Eriksson, E. E., Zaman, F., Hammarstedt, A., Isaksson, H., Bally, M., Kassem, A., Lindholm, C. & 11 othersSandberg, O., Aspenberg, P., Sävendahl, L., Feng, J. Q., Tuckermann, J., Tuukkanen, J., Poutanen, M., Baron, R., Lerner, U. H., Gori, F. & Ohlsson, C., 2014, In : Nature Medicine. 20, 11, p. 1279-1288

    Research output: Contribution to journalArticle

  16. 2012
  17. Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1

    Stock, K., Kumar, J., Synowitz, M., Petrosino, S., Imperatore, R., Smith, E. S. J., Wend, P., Purfuerst, B., Nuber, U., Gurok, U., Matyash, V., Waelzlein, J-H., Chirasani, S. R., Dittmar, G., Cravatt, B. F., Momma, S., Lewin, G. R., Ligresti, A., De Petrocellis, L., Cristino, L. & 3 othersDi Marzo, V., Kettenmann, H. & Glass, R., 2012, In : Nature Medicine. 18, 8, p. 1232

    Research output: Contribution to journalArticle

  18. 2011
  19. Stem cell gene expression programs influence clinical outcome in human leukemia

    Eppert, K., Takenaka, K., Lechman, E. R., Waldron, L., Björn Nilsson, van Galen, P., Metzeler, K. H., Poeppl, A., Ling, V., Beyene, J., Canty, A. J., Danska, J. S., Bohlander, S. K., Buske, C., Minden, M. D., Golub, T. R., Jurisica, I., Ebert, B. L. & Dick, J. E., 2011 Aug 28, In : Nature Medicine. 17, 9, p. 1086-93 8 p.

    Research output: Contribution to journalArticle

  20. Metabolite profiles and the risk of developing diabetes

    Wang, T. J., Larson, M. G., Vasan, R. S., Cheng, S., Rhee, E. P., McCabe, E., Lewis, G. D., Fox, C. S., Jacques, P. F., Fernandez, C., O'Donnell, C. J., Carr, S. A., Mootha, V. K., Florez, J. C., Souza, A., Olle Melander, Clish, C. B. & Gerszten, R. E., 2011, In : Nature Medicine. 17, 4, p. 448-U83

    Research output: Contribution to journalArticle

  21. Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia

    Coulon, S., Dussiot, M., Grapton, D., Maciel, T. T., Wang, P. H. M., Callens, C., Tiwari, M. K., Agarwal, S., Fricot, A., Vandekerckhove, J., Tamouza, H., Zermati, Y., Ribeil, J-A., Djedaini, K., Oruc, Z., Pascal, V., Courtois, G., Arnulf, B., Alyanakian, M-A., Mayeux, P. & 6 othersTomas Leanderson, Benhamou, M., Cogne, M., Monteiro, R. C., Hermine, O. & Moura, I. C., 2011, In : Nature Medicine. 17, 11, p. 1456-U163

    Research output: Contribution to journalArticle

  22. 2010
  23. Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

    Quigley, M., Pereyra, F., Nilsson, B., Porichis, F., Fonseca, C., Eichbaum, Q., Julg, B., Jesneck, J. L., Brosnahan, K., Imam, S., Russell, K., Toth, I., Piechocka-Trocha, A., Dolfi, D., Angelosanto, J., Crawford, A., Shin, H., Kwon, D. S., Zupkosky, J., Francisco, L. & 6 othersFreeman, G. J., Wherry, E. J., Kaufmann, D. E., Walker, B. D., Ebert, B. & Haining, W. N., 2010 Oct, In : Nature Medicine. 16, 10, p. 1147-51 5 p.

    Research output: Contribution to journalArticle

  24. A key role for orexin in panic anxiety

    Johnson, P. L., Truitt, W., Fitz, S. D., Minick, P. E., Dietrich, A., Sanghani, S., Lil Träskman Bendz, Goddard, A. W., Lena Brundin & Shekhar, A., 2010, In : Nature Medicine. 16, 1, p. 111-U149

    Research output: Contribution to journalArticle

  25. 2009
  26. The parametric response map is an imaging biomarker for early cancer treatment outcome

    Galbán, C. J., Chenevert, T. L., Meyer, C. R., Tsien, C., Lawrence, T. S., Hamstra, D. A., Junck, L., Pia C Sundgren, Johnson, T. D., Ross, D. J., Rehemtulla, A. & Ross, B. D., 2009 May, In : Nature Medicine. 15, 5, p. 572-6 5 p.

    Research output: Contribution to journalArticle

  27. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer.

    Liu, W., Laitinen, S., Khan, S., Mauno Vihinen, Kowalski, J., Yu, G., Chen, L., Ewing, C. M., Eisenberger, M. A., Carducci, M. A., Nelson, W. G., Yegnasubramanian, S., Luo, J., Wang, Y., Xu, J., Isaacs, W. B., Visakorpi, T. & Bova, G. S., 2009, In : Nature Medicine. 15, 5, p. 559-565

    Research output: Contribution to journalLetter

  28. Endothelial basement membrane laminin alpha 5 selectively inhibits T lymphocyte extravasation into the brain

    Wu, C., Fredrik Ivars, Anderson, P., Hallmann, R., Vestweber, D., Nilsson, P., Robenek, H., Tryggvason, K., Song, J., Korpos, E., Loser, K., Beissert, S., Georges-Labouesse, E. & Sorokin, L. M., 2009, In : Nature Medicine. 15, 5, p. 519-527

    Research output: Contribution to journalArticle

  29. 2008
  30. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.

    Jia-Yi Li, Elisabet Englund, Holton, J. L., Soulet, D., Hagell, P., Lees, A. J., Lashley, T., Quinn, N. P., Rehncrona, S., Anders Björklund, Håkan Widner, Revesz, T., Olle Lindvall & Brundin, P., 2008, In : Nature Medicine. 14, p. 501-503

    Research output: Contribution to journalArticle

  31. Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins

    Cirl, C., Wieser, A., Yadav, M., Duerr, S., Schubert, S., Fischer, H., Stappert, D., Wantia, N., Rodriguez, N., Wagner, H., Catharina Svanborg & Miethke, T., 2008, In : Nature Medicine. 14, 4, p. 399-406

    Research output: Contribution to journalArticle

  32. 2007
  33. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

    Ray, S., Britschgi, M., Herbert, C., Takeda-Uchimura, Y., Boxer, A., Blennow, K., Friedman, L. F., Galasko, D. R., Jutel, M., Karydas, A., Kaye, J. A., Leszek, J., Miller, B. L., Minthon, L., Quinn, J. F., Rabinovici, G. D., Robinson, W. H., Sabbagh, M. N., So, Y. T., Sparks, D. L. & 5 othersTabaton, M., Tinklenberg, J., Yesavage, J. A., Tibshirani, R. & Wyss-Coray, T., 2007, In : Nature Medicine. 13, 11, p. 1359-1362

    Research output: Contribution to journalArticle

  34. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

    Zeisberg, E. M., Tarnavski, O., Zeisberg, M., Dorfman, A. L., McMullen, J. R., Gustafsson, E., Chandraker, A., Yuan, X., Pu, W. T., Roberts, A. B., Neilson, E. G., Sayegh, M. H., Izumo, S. & Kalluri, R., 2007, In : Nature Medicine. 13, 8, p. 952-961

    Research output: Contribution to journalArticle

  35. Large stem cell grafts could lead to erroneous interpretations of behavioral results?

    Christophersen, N. & Brundin, P., 2007, In : Nature Medicine. 13, 2, p. 118-118

    Research output: Contribution to journalLetter

  36. 2006
  37. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE.

    Liu, Y., Teige, I., Birnir, B. & Issazadeh, S., 2006, In : Nature Medicine. 12, 5, p. 518-525

    Research output: Contribution to journalArticle

  38. 2005
  39. Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia.

    Anders Castor, Nilsson, L., Åstrand-Grundström, I., Buitenhuis, M., Ramirez, C., Anderson, K., Strömbeck, B., Garwicz, S., Békássy, A., Schmiegelow, K., Lausen, B., Hokland, P., Lehmann, S., Gunnar Juliusson, Bertil Johansson & Jacobsen, S. E. W., 2005, In : Nature Medicine. 11, 6, p. 630-637

    Research output: Contribution to journalArticle

  40. 2004
  41. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation.

    Nygren, J., Jovinge, S., Breitbach, M., Petter Säwén, Röll, W., Hescheler, J., Taneera, J., Fleischmann, B. K. & Jacobsen, S. E. W., 2004, In : Nature Medicine. 10, 5, p. 494-501

    Research output: Contribution to journalArticle

  42. Regulation of angiogenesis by tissue factor cytoplasmic domain signaling

    Mattias Belting, Dorrell, M. I., Sandgren, S., Aguilar, E., Ahamed, J., Dorfleutner, A., Carmeliet, P., Mueller, B. M., Friedlander, M. & Ruf, W., 2004, In : Nature Medicine. 10, 5, p. 502-509

    Research output: Contribution to journalArticle

  43. Vitamin A helps gut T cells find their way in the dark.

    Bengt Johansson Lindbom & William Agace, 2004, In : Nature Medicine. 10, 12, p. 1300-1301

    Research output: Contribution to journalLetter

  44. 2003
  45. Predicting the future of breast cancer.

    Åke Borg, Mårten Fernö & Peterson, C., 2003, In : Nature Medicine. 9, 1, p. 16-18

    Research output: Contribution to journalLetter

  46. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma.

    Gustav Mattiasson, Shamloo, M., Gidö, G., Mathi, K., Tomasevic, G., Yi, S., Warden, C. H., Castilho, R. F., Melcher, T., Gonzalez-Zulueta, M., Nikolich, K. & Tadeusz Wieloch, 2003, In : Nature Medicine. 9, 8, p. 1062-1068

    Research output: Contribution to journalArticle

  47. 2002
  48. Interleukin-6-deficient mice develop mature-onset obesity

    Wallenius, V., Wallenius, K., Bo Ahrén, Rudling, M., Carlsten, H., Dickson, SL., Ohlsson, C. & Jansson, JO., 2002, In : Nature Medicine. 8, 1, p. 75-79

    Research output: Contribution to journalArticle

  49. Neuronal replacement from endogenous precursors in the adult brain after stroke.

    Andreas Arvidsson, Collin, T., Deniz Kirik, Zaal Kokaia & Olle Lindvall, 2002, In : Nature Medicine. 8, 9, p. 963-970

    Research output: Contribution to journalArticle

  50. Streptococcus pyogenes and phagocytic killing.

    von Pawel-Rammingen, U., Johansson, B., Tapper, H. & Lars Björck, 2002, In : Nature Medicine. 8, 10, p. 1043-1044

    Research output: Contribution to journalLetter

  51. 2001
  52. Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

    Khan, J., Wei, JS., Markus Ringnér, Lao Saal, Ladanyi, M., Westermann, F., Berthold, F., Schwab, M., Antonescu, CR., Peterson, C. & Meltzer, PS., 2001, In : Nature Medicine. 7, 6, p. 673-679

    Research output: Contribution to journalArticle

  53. Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis

    Angelillo-Scherrer, A., Garcia de Frutos, P., Aparicio, C., Melis, E., Savi, P., Lupu, F., Arnout, J., Dewerchin, M., Hoylaerts, M. F., Herbert, J-M., Collen, D., Björn Dahlbäck & Carmeliet, P., 2001, In : Nature Medicine. 7, 2, p. 215-221

    Research output: Contribution to journalArticle

  54. Heparin-binding protein (HBP/CAP37): A missing link in neutrophil-evoked alteration of vascular permeability

    Gautam, N., Olofsson, M., Heiko Herwald, Iversen, L. F., Lundgren-Åkerlund, E., Hedqvist, P., Arfors, K-E., Flodgaard, H. & Lindbom, L., 2001, In : Nature Medicine. 7, 10, p. 1123-1127

    Research output: Contribution to journalArticle

  55. Hereditary prostate cancer: a new piece of the puzzle.

    Åke Borg, 2001, In : Nature Medicine. 7, 2, p. 153-155

    Research output: Contribution to journalLetter

  56. Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis

    Sakai, T., Johnson, K. J., Murozono, M., Sakai, K., Magnuson, M. A., Tadeusz Wieloch, Tobias Cronberg, Isshiki, A., Erickson, H. P. & Fässler, R., 2001, In : Nature Medicine. 7, 3, p. 324-330

    Research output: Contribution to journalArticle

  57. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

    Carmeliet, P., Moons, L., Luttun, A., Vincenti, V., Compernolle, V., De Mol, M., Wu, Y., Bono, F., Devy, L., Beck, H., Scholz, D., Acker, T., DiPalma, T., Dewerchin, M., Noel, A., Stalmans, I., Barra, A., Blacher, S., Vandendriessche, T., Pontén, A. & 9 othersEriksson, U., Plate, K. H., Foidart, J-M., Schaper, W., Charnock-Jones, D. S., Hicklin, D. J., Herbert, J-M., Collen, D. & Persico, M. G., 2001, In : Nature Medicine. 7, 5, p. 575-583

    Research output: Contribution to journalArticle

  58. 1999
  59. Caspase inhibition reduces apoptosis and increases survival of nigral transplants

    Schierle, G., Oskar Hansson, Leist, M., Nicotera, P., Håkan Widner & Brundin, P., 1999, In : Nature Medicine. 5, 1, p. 97-100

    Research output: Contribution to journalArticle

  60. 1997
  61. Testis-derived Sertoli cells have a trophic effect on dopamine neurons and alleviate hemiparkinsonism in rats

    Sanberg, P. R., Borlongan, C. V., A I Othberg, Saporta, S., Freeman, T. B. & Cameron, D. F., 1997 Oct, In : Nature Medicine. 3, 10, p. 1129-32 4 p.

    Research output: Contribution to journalArticle

  62. 1995
  63. Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease

    Nakao, N., Frodl, E. M., H Widner, Carlson, E., Eggerding, F. A., Epstein, C. J. & Brundin, P., 1995 Mar, In : Nature Medicine. 1, 3, p. 226-31 6 p.

    Research output: Contribution to journalArticle