Neurobiology of Disease, 0969-9961

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  1. Article
  2. Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration

    Höglund, K., Schussler, N., Kvartsberg, H., Smailovic, U., Brinkmalm, G., Liman, V., Becker, B., Zetterberg, H., Cedazo-Minguez, A., Shorena Janelidze, Lefevre, I. A., Eyquem, S., Oskar Hansson & Blennow, K., 2020 Feb, In : Neurobiology of Disease. 134, 104645.

    Research output: Contribution to journalArticle

  3. Heritability and genetic variance of dementia with Lewy bodies

    Guerreiro, R., Elisabet Londos, Bras, J. & International Parkinson's Disease Genomics Consortium (IPDGC), 2019, In : Neurobiology of Disease. 127, p. 492-501 10 p.

    Research output: Contribution to journalArticle

  4. Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease

    Mendonça, C. F., Magdalena Kuras, Fábio César Sousa Nogueira, Plá, I., Hortobágyi, T., Csiba, L., Palkovits, M., Renner, É., Döme, P., György Marko-Varga, Domont, G. B. & Melinda Rezeli, 2019, In : Neurobiology of Disease. 130, 104509.

    Research output: Contribution to journalArticle

  5. Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation

    Michael Aagaard Andersen, Christensen, K. V., Badolo, L., Smith, G. P., Jeggo, R., Jensen, P. H., Andersen, K. J. & Sotty, F., 2018 Aug, In : Neurobiology of Disease. 116, p. 13-27 15 p.

    Research output: Contribution to journalArticle

  6. Prion-like seeding and nucleation of intracellular amyloid-β

    Tomas T. Olsson, Oxana Klementieva & Gunnar K. Gouras, 2018 May 1, In : Neurobiology of Disease. 113, p. 1-10 10 p.

    Research output: Contribution to journalArticle

  7. Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum

    Aldrin-Kirk, P., Andreas Heuer, Rylander Ottosson, D., Marcus Davidsson, Mattsson, B. & Tomas Björklund, 2018 Jan, In : Neurobiology of Disease. 109, p. 148-162

    Research output: Contribution to journalArticle

  8. Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease

    Richetin, K., Moulis, M., Millet, A., Arràzola, M. S., Andraini, T., Hua, J., Davezac, N., Laurent Roybon, Belenguer, P., Miquel, M. C. & Rampon, C., 2017 Jun 1, In : Neurobiology of Disease. 102, p. 113-124 12 p.

    Research output: Contribution to journalArticle

  9. Functional validation of ABHD12 mutations in the neurodegenerative disease PHARC

    Tingaud-Sequeira, A., Raldúa, D., Lavie, J., Mathieu, G., Bordier, M., Knoll-Gellida, A., Rambeau, P., Coupry, I., André, M., Malm, E., Möller, C., Sten Andreasson, Rendtorff, N. D., Tranebjærg, L., Koenig, M., Lacombe, D., Goizet, C. & Babin, P. J., 2017 Feb 1, In : Neurobiology of Disease. 98, p. 36-51 16 p.

    Research output: Contribution to journalArticle

  10. Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model

    Lerner, R. P., Bimpisidis, Z., Agorastos, S., Scherrer, S., Dewey, S. L., Angela Cenci Nilsson & Eidelberg, D., 2016 Dec 1, In : Neurobiology of Disease. 96, p. 31-37 7 p.

    Research output: Contribution to journalArticle

  11. Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors.

    Nikitidou, L., Esbjörn Melin, Christiansen, S. H., Gøtzsche, C. R., Cifra, A., Woldbye, D. P. D. & Merab Kokaia, 2016, In : Neurobiology of Disease. 86, nov 19, p. 52-61

    Research output: Contribution to journalArticle

  12. Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease.

    Nordström, U., Beauvais, G., Ghosh, A., Pulikkaparambil Sasidharan, B. C., Lundblad, M., Fuchs, J., Joshi, R. L., Lipton, J. W., Roholt, A., Medicetty, S., Feinstein, T. N., Steiner, J., Escobar Galvis, M. L., Prochiantz, A. & Brundin, P., 2015, In : Neurobiology of Disease. 73, p. 70-82

    Research output: Contribution to journalArticle

  13. Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.

    Buck, K., Landeck, N., Ulusoy, A., Majbour, N. K., El-Agnaf, O. M. A. & Deniz Kirik, 2015, In : Neurobiology of Disease. 78, Mar 25, p. 100-114

    Research output: Contribution to journalArticle

  14. Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.

    Nishant Narayanan Vaikath, Majbour, N. K., Paleologou, K. E., Ardah, M. T., van Dam, E., van de Berg, W. D. J., Forrest, S. L., Parkkinen, L., Gai, W-P., Hattori, N., Takanashi, M., Lee, S-J., Mann, D. M. A., Imai, Y., Halliday, G. M., Jia-Yi Li & El-Agnaf, O. M. A., 2015, In : Neurobiology of Disease. 79, p. 81-99

    Research output: Contribution to journalArticle

  15. A cell culture model for monitoring α-synuclein cell-to-cell transfer.

    Reyes, J. F., Tomas Olsson, Lamberts, J. T., Devine, M. J., Kunath, T. & Brundin, P., 2015, In : Neurobiology of Disease. 77, Jul 16, p. 266-275

    Research output: Contribution to journalArticle

  16. Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease.

    Cisbani, G., Drouin-Ouellet, J., Gibrat, C., Saint-Pierre, M., Lagacé, M., Badrinarayanan, S., Lavallée-Bourget, M. H., Charest, J., Chabrat, A., Boivin, L., Lebel, M., Bousquet, M., Lévesque, M. & Cicchetti, F., 2015, In : Neurobiology of Disease. 82, p. 430-444

    Research output: Contribution to journalArticle

  17. Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models.

    Träger, U., Andre, R., Magnusson-Lind, A., Miller, J. R. C., Connolly, C., Weiss, A., Grueninger, S., Silajdzic, E., Smith, D. L., Leavitt, B. R., Bates, G. P., Maria Björkqvist & Tabrizi, S. J., 2015, In : Neurobiology of Disease. 73, p. 388-398

    Research output: Contribution to journalArticle

  18. Inflammation without neuronal death triggers striatal neurogenesis comparable to stroke.

    Chapman, K., Ge, R., Emanuela Monni, Tatarishvili, J., Henrik Ahlenius, Andreas Arvidsson, Ekdahl, C., Olle Lindvall & Zaal Kokaia, 2015, In : Neurobiology of Disease. 83, Aug 20, p. 1-15

    Research output: Contribution to journalArticle

  19. Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.

    Fredrik Berglind, Marco Ledri, Sørensen, A. T., Nikitidou, L., Melis, M., Bielefeld, P., Deniz Kirik, Deisseroth, K., My Andersson & Merab Kokaia, 2014, In : Neurobiology of Disease. 65, p. 133-141

    Research output: Contribution to journalArticle

  20. The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.

    Shin, E., Lisci, C., Tronci, E., Fidalgo, C., Stancampiano, R., Anders Björklund & Carta, M., 2014, In : Neurobiology of Disease. 62, p. 233-240

    Research output: Contribution to journalArticle

  21. GABAA receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia.

    Mele, M., Ribeiro, L., Inacio, A., Tadeusz Wieloch & Duarte, C. B., 2014, In : Neurobiology of Disease.

    Research output: Contribution to journalArticle

  22. Comparison of rating scales used to evaluate L-DOPA-induced dyskinesia in the 6-OHDA lesioned rat

    Breger, L. S., Dunnett, S. B. & Lane, E. L., 2013 Feb, In : Neurobiology of Disease. 50, p. 142-50 9 p.

    Research output: Contribution to journalArticle

  23. Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease

    Febbraro, F., Gurdal Sahin, Farran, A., Soares, S., Jensen, P. H., Deniz Kirik & Romero-Ramos, M., 2013, In : Neurobiology of Disease. 56, p. 47-58

    Research output: Contribution to journalArticle

  24. Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

    Ribeiro, D., Goya, R. L., Ravindran, G., Vuono, R., Parish, C. L., Foldi, C., Piroth, T., Yang, S., Malin Parmar, Nikkhah, G., Hjerling-Leffler, J., Olle Lindvall, Barker, R. & Arenas, E., 2013, In : Neurobiology of Disease. 49, p. 118-127

    Research output: Contribution to journalArticle

  25. A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.

    Christian Hansen, Tomas Björklund, Petit, G., Lundblad, M., Murmu, R., Brundin, P. & Jia-Yi Li, 2013, In : Neurobiology of Disease. 56C, April,30, p. 145-155

    Research output: Contribution to journalArticle

  26. Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures

    Gotzsche, C. R., Nikitidou, L., Toft Sörensen, A., Olesen, M. V., Sorensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, D. P. D. & Merab Kokaia, 2012, In : Neurobiology of Disease. 45, 1, p. 288-296

    Research output: Contribution to journalArticle

  27. Dysregulated dopamine storage increases the vulnerability to alpha-synuclein in nigral neurons

    Ulusoy, A., Tomas Björklund, Buck, K. & Deniz Kirik, 2012, In : Neurobiology of Disease. 47, 3, p. 367-377

    Research output: Contribution to journalArticle

  28. Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.

    Decressac, M., Mattsson, B., Lundblad, M., Weikop, P. & Anders Björklund, 2012, In : Neurobiology of Disease. 45, 3, p. 939-953

    Research output: Contribution to journalArticle

  29. Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.

    Shin, E., Garcia, J., Winkler, C., Anders Björklund & Carta, M., 2012, In : Neurobiology of Disease. 47, 3, p. 393-406

    Research output: Contribution to journalArticle

  30. Cleavage of the vesicular glutamate transporters under excitotoxic conditions

    Lobo, A. C., Gomes, J. R., Catarino, T., Mele, M., Fernandez, P., Inacio, A., Bahr, B. A., Santos, A. E., Tadeusz Wieloch, Carvalho, A. L. & Duarte, C. B., 2011, In : Neurobiology of Disease. 44, 3, p. 292-303

    Research output: Contribution to journalArticle

  31. Apoptosis-inducing factor mediates dopaminergic cell death in response to lps-induced inflammatory stimulus Evidence in Parkinson's disease patients.

    Burguillos Garcia, M., Hajji, N., Englund, E., Persson, A., Angela Cenci Nilsson, Machado, A., Cano, J., Joseph, B. & Venero, J. L., 2011, In : Neurobiology of Disease. 41, p. 177-188

    Research output: Contribution to journalArticle

  32. Gastrointestinal dysfunction contributes to weight loss in Huntington's disease mice.

    van der Burg, J. M., Winqvist, A., Aziz, N. A., Maat-Schieman, M. L. C., Roos, R. A. C., Bates, G. P., Brundin, P., Maria Björkqvist & Nils Wierup, 2011, In : Neurobiology of Disease. 44, p. 1-8

    Research output: Contribution to journalArticle

  33. A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys.

    Daniella Rylander, Iderberg, H., Li, Q., Dekundy, A., Zhang, J., Li, H., Baishen, R., Danysz, W., Bezard, E. & Angela Cenci Nilsson, 2010, In : Neurobiology of Disease. 39, p. 352-361

    Research output: Contribution to journalArticle

  34. Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis.

    Soneson, C., Fontes, M., Zhou, Y., Vladimir Denisov, Paulsen, J. S., Deniz Kirik & Åsa Petersén, 2010, In : Neurobiology of Disease. 40, p. 531-543

    Research output: Contribution to journalArticle

  35. Increased levels of cocaine and amphetamine regulated transcript in two animal models of depression and anxiety.

    Wiehager, S., Beiderbeck, D. I., Gruber, S. H. M., El-Khoury, A., Wamsteeker, J., Neumann, I. D., Åsa Petersén & Mathé, A. A., 2009, In : Neurobiology of Disease. 34, p. 375-380

    Research output: Contribution to journalArticle

  36. Increased metabolism in the R6/2 mouse model of Huntington's disease.

    van der Burg, J. M., Karl Bacos, Wood, N. I., Andreas Lindqvist, Nils Wierup, Woodman, B., Wamsteeker, J., Ruben Smith, Tomas Deierborg, Kuhar, M. J., Bates, G. P., Hindrik Mulder, Charlotte Erlanson-Albertsson, Morton, J., Brundin, P., Åsa Petersén & Maria Björkqvist, 2008, In : Neurobiology of Disease. 29, 1, p. 41-51

    Research output: Contribution to journalArticle

  37. l-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation

    Picconi, B., Paille, V., Ghiglieri, V., Bagetta, V., Barone, I., Lindgren, H., Bernardi, G., Angela Cenci Nilsson & Calabresi, P., 2008, In : Neurobiology of Disease. 29, 2, p. 327-335

    Research output: Contribution to journalArticle

  38. Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease.

    Lane, E., Soulet, D., Vercammen, L., Angela Cenci Nilsson & Brundin, P., 2008, In : Neurobiology of Disease. 32, p. 220-228

    Research output: Contribution to journalArticle

  39. Re-evaluation of mitochondrial permeability transition as a primary neuroprotective target of minocycline.

    Månsson, R., Magnus Hansson, Morota, S., Uchino, H., Christine Ekdahl Clementson & Eskil Elmer, 2007, In : Neurobiology of Disease. 25, p. 198-205

    Research output: Contribution to journalArticle

  40. Testicular degeneration in Huntington disease

    Van Raamsdonk, J. M., Murphy, Z., Selva, D. M., Hamidizadeh, R., Pearson, J., Åsa Petersén, Maria Björkqvist, Muir, C., Mackenzie, I. R., Hammond, G. L., Vogl, A. W., Hayden, M. R. & Leavitt, B. R., 2007, In : Neurobiology of Disease. 26, 3, p. 512-520

    Research output: Contribution to journalArticle

  41. Nerve growth factor promotes survival of new neurons in the adult hippocampus.

    Frielingsdorf, H., Simpson, D. R., Thal, L. J. & Pizzo, D. P., 2007, In : Neurobiology of Disease. 26, 1, p. 47-55

    Research output: Contribution to journalArticle

  42. The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat.

    Lane, E., Winkler, C., Brundin, P. & Angela Cenci Nilsson, 2006, In : Neurobiology of Disease. 22, 2, p. 334-345

    Research output: Contribution to journalArticle

  43. Ventral tegmental area dopamine neurons are resistant to human mutant alpha-synuclein overexpression.

    Maingay, M., Romero-Ramos, M., Carta, M. & Deniz Kirik, 2006, In : Neurobiology of Disease. 23, 3, p. 522-532

    Research output: Contribution to journalArticle

  44. Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes

    Maria Swanberg, Duvefelt, K., Diez, M., Hillert, J., Olsson, T., Piehl, F. & Lidman, O., 2006, In : Neurobiology of Disease. 24, 1, p. 67-88 22 p.

    Research output: Contribution to journalArticle

  45. Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice.

    Gil, J., Mohapel, P., Araujo, I., Popovic, N., Jia-Yi Li, Brundin, P. & Åsa Petersén, 2005, In : Neurobiology of Disease. 20, 3, p. 744-751

    Research output: Contribution to journalArticle

  46. Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse

    Pirttila, T. J., Lukasiuk, K., Håkansson, K., Anders Grubb, Magnus Abrahamson & Pitkanen, A., 2005, In : Neurobiology of Disease. 20, 2, p. 241-253

    Research output: Contribution to journalArticle

  47. Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors.

    Woldbye, D. P. D., Nanobashvili, A., Toft Sörensen, A., Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P. & Merab Kokaia, 2005, In : Neurobiology of Disease. 20, 3, p. 760-772

    Research output: Contribution to journalArticle

  48. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice

    Malm, T. M., Koistinaho, M., Parepalo, M., Vatanen, T., Ooka, A., Stefan Karlsson & Koistinahoa, J., 2005, In : Neurobiology of Disease. 18, 1, p. 134-142

    Research output: Contribution to journalArticle

  49. Effects of pulsatile L-DOPA treatment in the double lesion rat model of striatonigral degeneration (multiple system atrophy)

    Stefanova, N., Lundblad, M., Tison, F., Poewe, W., Angela Cenci Nilsson & Wenning, GK., 2004, In : Neurobiology of Disease. 15, 3, p. 630-639

    Research output: Contribution to journalArticle

  50. Transcriptome analysis in a rat model of L-DOPA-induced dyskinesia

    Konradi, C., Jenny Westin, Carta, M., Eaton, ME., Kuter, K., Dekundy, A., Lundblad, M. & Angela Cenci Nilsson, 2004, In : Neurobiology of Disease. 17, 2, p. 219-236

    Research output: Contribution to journalArticle

  51. A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function.

    Lundblad, M., Picconi, B., Lindgren, H. & Angela Cenci Nilsson, 2004, In : Neurobiology of Disease. 16, 1, p. 110-123

    Research output: Contribution to journalArticle

  52. Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABA(B) autoreceptors in layer III of the entorhinal cortex

    Gloveli, T., Behr, J., Dugladze, T., Zaal Kokaia, Merab Kokaia & Heinemann, U., 2003, In : Neurobiology of Disease. 13, 3, p. 203-212

    Research output: Contribution to journalArticle

  53. Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons

    O'Malley, KL., Liu, J., Lotharius, J. & Holtz, W., 2003, In : Neurobiology of Disease. 14, 1, p. 43-51

    Research output: Contribution to journalArticle

  54. Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival.

    Christine Ekdahl Clementson, Zhu, C., Bonde, S., Bahr, B. A., Blomgren, K. & Olle Lindvall, 2003, In : Neurobiology of Disease. 14, 3, p. 513-523

    Research output: Contribution to journalArticle

  55. Evidence for Dysfunction of the Nigrostriatal Pathway in the R6/1 Line of Transgenic Huntington's Disease Mice.

    Åsa Petersén, Puschban, Z., Lotharius, J., NicNiocaill, B., Wiekop, P., O'Connor, W. T. & Brundin, P., 2002, In : Neurobiology of Disease. 11, 1, p. 134-146

    Research output: Contribution to journalArticle

  56. Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia

    S Janelidze, Hu, BI-R., P Siesjö & Siesjö, B. K., 2001 Feb, In : Neurobiology of Disease. 8, 1, p. 147-154

    Research output: Contribution to journalArticle

  57. Alterations in cortical and basal ganglia levels of opioid receptor binding in a rat model of L-DOPA-induced dyskinesia

    Johansson, P. A., Andersson, M., Andersson, K. E. & M. A. Cenci, 2001, In : Neurobiology of Disease. 8, 2, p. 220-239 20 p.

    Research output: Contribution to journalArticle

  58. Debate/Note/Editorial
  59. Special Issue: Viral delivery of genes: new frontiers Introduction

    Kordower, J. H. & Deniz Kirik, 2012, In : Neurobiology of Disease. 48, 2, p. 151-152

    Research output: Contribution to journalDebate/Note/Editorial

  60. Review article
  61. Gene therapy for Parkinson's disease: Disease modification by GDNF family of ligands

    Deniz Kirik, Cederfjäll, E., Halliday, G. & Petersén, 2017 Jan 1, In : Neurobiology of Disease. 97, p. 179-188 10 p.

    Research output: Contribution to journalReview article

  62. Rodent models of impulsive compulsive behaviors in Parkinson's disease: how far have we reached?

    Angela Cenci Nilsson, Veronica Francardo, O'Sullivan, S. S. & Lindgren, H., 2015, In : Neurobiology of Disease. 82, aug 29, p. 561-573

    Research output: Contribution to journalReview article

  63. Spreading of α-synuclein in the face of axonal transport deficits in Parkinson's disease: A speculative synthesis.

    Lamberts, J. T., Hildebrandt, E. & Brundin, P., 2015, In : Neurobiology of Disease. 77, Jul 15, p. 276-283

    Research output: Contribution to journalReview article

  64. Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.

    Thompson, L. & Anders Björklund, 2015, In : Neurobiology of Disease. 79, Apr 22, p. 28-40

    Research output: Contribution to journalReview article

  65. Key factors determining the efficacy of gene therapy for continuous DOPA delivery in the Parkinsonian brain

    Cederfjäll, E., Gurdal Sahin & Deniz Kirik, 2012, In : Neurobiology of Disease. 48, 2, p. 222-227

    Research output: Contribution to journalReview article

  66. Interactions of A beta with endogenous anti-inflammatory agents: a basis for chronic neuroinflammation in Alzheimer's disease.

    Sabina Janciauskiene, Sun, Y. & Wright, H. T., 2002, In : Neurobiology of Disease. 10, 3, p. 187-200

    Research output: Contribution to journalReview article

  67. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease

    Anders Björklund, Rosenblad, C., Winkler, C. & Deniz Kirik, 1997, In : Neurobiology of Disease. 4, 3-4, p. 186-200

    Research output: Contribution to journalReview article