Science Translational Medicine, 1946-6242

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  1. 2020
  2. A dual-action peptide-containing hydrogel targets wound infection and inflammation

    Manoj Puthia, Marta Butrym, Jitka Petrlova, Ann Charlotte Strömdahl, Madelene Andersson, Sven Kjellström & Artur Schmidtchen, 2020 Jan 1, In : Science Translational Medicine. 12, 524, eaax6601.

    Research output: Contribution to journalArticle

  3. Apoptosis of hematopoietic progenitor-derived adipose tissue-resident macrophages contributes to insulin resistance after myocardial infarction

    Sathish Babu Vasamsetti, Emilie Coppin, Xinyi Zhang, Jonathan Florentin, Sasha Koul, Matthias Götberg, Andrew S. Clugston, Floyd Thoma, John Sembrat, Grant C. Bullock, Dennis Kostka, Claudette M. St Croix, Ansuman Chattopadhyay, Mauricio Rojas, Suresh R. Mulukutla & Partha Dutta, 2020, In : Science Translational Medicine. 12, 553, eaaw0638.

    Research output: Contribution to journalArticle

  4. 2019
  5. Treating murine inflammatory diseases with an anti-erythrocyte antibody

    Andrew R. Crow, Rick Kapur, Sandra Koernig, Ian K. Campbell, Chao Ching Jen, Patrick J. Mott, Danielle Marjoram, Ramsha Khan, Michael Kim, Jennifer Brasseit, Yoelys Cruz-Leal, Alaa Amash, Simrat Kahlon, Issaka Yougbare, Heyu Ni, Adrian W. Zuercher, Fabian Käsermann, John W. Semple & Alan H. Lazarus, 2019 Aug 21, In : Science Translational Medicine. 11, 506, eaau8217.

    Research output: Contribution to journalArticle

  6. The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

    Yuetiva Deming, Fabia Filipello, Francesca Cignarella, Claudia Cantoni, Simon Hsu, Robert Mikesell, Zeran Li, Jorge L. Del-Aguila, Umber Dube, Fabiana Geraldo Farias, Joseph Bradley, John Budde, Laura Ibanez, Maria Victoria Fernandez, Kaj Blennow, Henrik Zetterberg, Amanda Heslegrave, Per M. Johansson, Johan Svensson, Bengt Nellgård & 16 others, Alberto Lleo, Daniel Alcolea, Jordi Clarimon, Lorena Rami, José Luis Molinuevo, Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Michael Ewers, Oscar Harari, Christian Haass, Thomas J. Brett, Bruno A. Benitez, Celeste M. Karch, Laura Piccio & Carlos Cruchaga, 2019 Aug 14, In : Science Translational Medicine. 11, 505, eaau2291.

    Research output: Contribution to journalArticle

  7. Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma

    Neeraj Jain, Keenan Hartert, Saber Tadros, Warren Fiskus, Ondrej Havranek, Man Chun John Ma, Alyssa Bouska, Tayla Heavican, Dhiraj Kumar, Qing Deng, Dalia Moore, Christine Pak, Chih Long Liu, Andrew J. Gentles, Elena Hartmann, Robert Kridel, Karin Ekstrom Smedby, Gunnar Juliusson, Richard Rosenquist, Randy D. Gascoyne & 13 others, Andreas Rosenwald, Filippo Giancotti, Sattva S. Neelapu, Jason Westin, Julie M. Vose, Matthew A. Lunning, Timothy Greiner, Scott Rodig, Javeed Iqbal, Ash A. Alizadeh, R. Eric Davis, Kapil Bhalla & Michael R. Green, 2019 Jun 19, In : Science Translational Medicine. 11, 497, eaav5599.

    Research output: Contribution to journalArticle

  8. 2018
  9. Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus

    Emmanuel Clave, Itauá Leston Araujo, Cécile Alanio, Etienne Patin, Jacob Bergstedt, Alejandra Urrutia, Silvia Lopez-Lastra, Yan Li, Bruno Charbit, Cameron Ross MacPherson, Milena Hasan, Breno Luiz Melo-Lima, Corinne Douay, Noémie Saut, Marine Germain, David Alexandre Trégouët, Pierre Emmanuel Morange, Magnus Fontes, Darragh Duffy, James Di Santo & 3 others, Lluis Quintana-Murci, Matthew L. Albert & Antoine Toubert, 2018 Sep 5, In : Science Translational Medicine. 10, 457, aao2966.

    Research output: Contribution to journalArticle

  10. The vermiform appendix impacts the risk of developing Parkinson’s disease

    Bryan A. Killinger, Zachary Madaj, Jacek W. Sikora, Nolwen Rey, Alec J. Haas, Yamini Vepa, Daniel Lindqvist, Honglei Chen, Paul M. Thomas, Patrik Brundin, Lena Brundin & Viviane Labrie, 2018, In : Science Translational Medicine. 10, 465, aar5280.

    Research output: Contribution to journalArticle

  11. 2017
  12. Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes

    Annika S. Axelsson, Emily Tubbs, Brig Mecham, Shaji Chacko, Hannah A. Nenonen, Yunzhao Tang, Jed W. Fahey, Jonathan M.J. Derry, Claes B. Wollheim, Nils Wierup, Morey W Haymond, Stephen H. Friend, Hindrik Mulder & Anders H. Rosengren, 2017 Jun 14, In : Science Translational Medicine. 9, 394, 4477.

    Research output: Contribution to journalArticle

  13. 2016
  14. Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis

    Daniel L J Thorek, Philip A. Watson, Sang Gyu Lee, Anson T. Ku, Stylianos Bournazos, Katharina Braun, Kwanghee Kim, Kjell Sjostrom, Michael G. Doran, Urpo Lamminmaki, Elmer Santos, Darren Veach, Mesruh Turkekul, Emily Casey, Jason S. Lewis, Diane S. Abou, Marise R H Van Voss, Peter T. Scardino, Sven Erik Strand, Mary L. Alpaugh & 4 others, Howard I. Scher, Hans Lilja, Steven M. Larson & David Ulmert, 2016 Nov 30, In : Science Translational Medicine. 8, 367, 367ra167.

    Research output: Contribution to journalArticle

  15. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

    Robert A. Scott, Daniel F. Freitag, Li Li, Audrey Y. Chu, Praveen Surendran, Robin Young, Niels Grarup, Alena Stancáková, Yuning Chen, Tibor V. Varga, Hanieh Yaghootkar, Jian'an Luan, Jing Hua Zhao, Sara M. Willems, Jennifer Wessel, Shuai Wang, Nisa Maruthur, Kyriaki Michailidou, Ailith Pirie, Sven J. Van Der Lee & 118 others, Christopher Gillson, Ali Amin Al Olama, Philippe Amouyel, Larraitz Arriola, Dominique Arveiler, Iciar Aviles-Olmos, Beverley Balkau, Aurelio Barricarte, Inês Barroso, Sara Benlloch Garcia, Joshua C. Bis, Stefan Blankenberg, Michael Boehnke, Heiner Boeing, Eric Boerwinkle, Ingrid B. Borecki, Jette Bork-Jensen, Sarah Bowden, Carlos Caldas, Muriel Caslake, L. Adrienne Cupples, Carlos Cruchaga, Jacek Czajkowski, Marcel Den Hoed, Janet A. Dunn, Helena M. Earl, Georg B. Ehret, Ele Ferrannini, Jean Ferrieres, Thomas Foltynie, Ian Ford, Nita G. Forouhi, Francesco Gianfagna, Carlos Gonzalez, Sara Grioni, Louise Hiller, Jan Håkan Jansson, Marit E. Jørgensen, J. Wouter Jukema, Rudolf Kaaks, Frank Kee, Nicola D. Kerrison, Timothy J. Key, Jukka Kontto, Zsofia Kote-Jarai, Aldi T. Kraja, Kari Kuulasmaa, Johanna Kuusisto, Allan Linneberg, Chunyu Liu, Gaëlle Marenne, Karen L. Mohlke, Andrew P. Morris, Kenneth Muir, Martina Müller-Nurasyid, Patricia B. Munroe, Carmen Navarro, Sune F. Nielsen, Peter M. Nilsson, Børge G. Nordestgaard, Chris J. Packard, Domenico Palli, Salvatore Panico, Gina M. Peloso, Markus Perola, Annette Peters, Christopher J. Poole, J. Ramón Quirós, Olov Rolandsson, Carlotta Sacerdote, Veikko Salomaa, María José Sánchez, Naveed Sattar, Stephen J. Sharp, Rebecca Sims, Nadia Slimani, Jennifer A. Smith, Deborah J. Thompson, Stella Trompet, Rosario Tumino, Daphne L. Van Der A, Yvonne T. Van Der Schouw, Jarmo Virtamo, Mark Walker, Klaudia Walter, Jean E. Abraham, Laufey T. Amundadottir, Adam S. Butterworth, Jennifer L. Aponte, Josée Dupuis, Douglas F. Easton, Rosalind A. Eeles, Jeanette Erdmann, Paul W. Franks, Timothy M. Frayling, Torben Hansen, Joanna M M Howson, Torben Jørgensen, Jaspal Kooner, Markku Laakso, Mark I. McCarthy, James S. Pankow, Oluf Pedersen, Elio Riboli, Jerome I. Rotter, Danish Saleheen, Nilesh J. Samani, Heribert Schunkert, Peter Vollenweider, Stephen O'Rahilly, Panos Deloukas, John Danesh, Mark O. Goodarzi, Sekar Kathiresan, James B. Meigs, Margaret G. Ehm, Nicholas J. Wareham & Dawn M. Waterworth, 2016 Jun 1, In : Science Translational Medicine. 8, 341, 341ra76.

    Research output: Contribution to journalArticle

  16. IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections

    Manoj Puthia, Ines Ambite, Caterina Cafaro, Daniel Butler, Yujing Huang, Nataliya Lutay, Gustav Rydström, Birgitta Gullstrand, Bhairavi Swaminathan, Aftab Nadeem, Björn Nilsson & Catharina Svanborg, 2016, In : Science Translational Medicine. 8, 336, 336RA59.

    Research output: Contribution to journalArticle

  17. 2015
  18. PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer

    Ana Bosch Campos, Zhiqiang Li, Anna Bergamaschi, Haley Ellis, Eneda Toska, Aleix Prat, Jessica J. Tao, Daniel E. Spratt, Nerissa T. Viola-Villegas, Pau Castel, Gerard Minuesa, Natasha Morse, Jordi Rodón, Yasir Ibrahim, Javier Cortes, Jose Perez-Garcia, Patricia Galvan, Judit Grueso, Marta Guzman, John A. Katzenellenbogen & 8 others, Michaelz Kharas, Jason S. Lewis, Maura Dickler, Violeta Serra, Neal Rosen, Sarat Chandarlapaty, Maurizio Scaltriti & José Baselga, 2015 Apr 15, In : Science Translational Medicine. 7, 283, p. 1-11 283ra51.

    Research output: Contribution to journalArticle

  19. Transglutaminase 4 as a prostate autoantigen in male subfertility.

    Nils Landegren, Donald Sharon, Anthony K Shum, Imran S Khan, Kayla J Fasano, Åsa Hallgren, Caroline Kampf, Eva Freyhult, Brita Ardesjö-Lundgren, Mohammad Alimohammadi, Sandra Rathsman, Jonas F Ludvigsson, Dan Lundh, Ruben Motrich, Virginia Rivero, Lawrence Fong, Aleksander Giwercman, Jan Gustafsson, Jaakko Perheentupa, Eystein S Husebye & 3 others, Mark S Anderson, Michael Snyder & Olle Kämpe, 2015, In : Science Translational Medicine. 7, 292, p. 292ra101

    Research output: Contribution to journalArticle

  20. 2014
  21. Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.

    Yunzhao Tang, Annika Axelsson, Peter Spégel, Lotta Andersson, Hindrik Mulder, Leif Groop, Erik Renström & Anders Rosengren, 2014, In : Science Translational Medicine. 6, 257, p. 257ra139

    Research output: Contribution to journalArticle

  22. 2013
  23. mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer

    Moshe Elkabets, Sadhna Vora, Dejan Juric, Natasha Morse, Mari Mino-Kenudson, Taru Muranen, Jessica Tao, Ana Bosch Campos, Jordi Rodon, Yasir H Ibrahim, Violeta Serra, Vanessa Rodrik-Outmezguine, Saswati Hazra, Sharat Singh, Phillip Kim, Cornelia Quadt, Manway Liu, Alan Huang, Neal Rosen, Jeffrey A Engelman & 2 others, Maurizio Scaltriti & José Baselga, 2013 Jul 31, In : Science Translational Medicine. 5, 196, p. 1-14 196ra99.

    Research output: Contribution to journalArticle

  24. NCR3/NKp30 Contributes to Pathogenesis in Primary Sjogren's Syndrome

    Sylvie Rusakiewicz, Gaetane Nocturne, Thierry Lazure, Michaela Semeraro, Caroline Flament, Sophie Caillat-Zucman, Damien Sene, Nicolas Delahaye, Eric Vivier, Kariman Chaba, Vichnou Poirier-Colame, Gunnel Nordmark, Maija-Leena Eloranta, Per Eriksson, Elke Theander, Helena Forsblad-d'Elia, Roald Omdal, Marie Wahren-Herlenius, Roland Jonsson, Lars Ronnblom & 9 others, Joanne Nititham, Kimberly E. Taylor, Christopher J. Lessard, Kathy L. Moser Sivils, Jacques-Eric Gottenberg, Lindsey A. Criswell, Corinne Miceli-Richard, Laurence Zitvogel & Xavier Mariette, 2013, In : Science Translational Medicine. 5, 195, p. 195ra96

    Research output: Contribution to journalArticle

  25. 2012
  26. Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics

    Ruth Huttenhain, Martin Soste, Nathalie Selevsek, Hannes Roest, Atul Sethi, Christine Carapito, Terry Farrah, Eric W. Deutsch, Ulrike Kusebauch, Robert L. Moritz, Emma Niméus, Oliver Rinner & Ruedi Aebersold, 2012, In : Science Translational Medicine. 4, 142, p. 142ra94

    Research output: Contribution to journalArticle

  27. Serotonin Neuron Loss and Nonmotor Symptoms Continue in Parkinson's Patients Treated with Dopamine Grafts

    Marios Politis, Kit Wu, Clare Loane, Niall P. Quinn, David J. Brooks, Wolfgang H. Oertel, Anders Björklund, Olle Lindvall & Paola Piccini, 2012, In : Science Translational Medicine. 4, 128

    Research output: Contribution to journalArticle

  28. α-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons.

    Mickael Decressac, Banafsheh Kadkhodaei, Bengt Mattsson, Ariadna Laguna, Thomas Perlmann & Anders Björklund, 2012, In : Science Translational Medicine. 4, 163, p. 163ra156

    Research output: Contribution to journalArticle

  29. 2011
  30. Gene therapy for Parkinson's disease shows promise.

    Anders Björklund & Tomas Björklund, 2011, In : Science Translational Medicine. 3, 79, p. 79ed1

    Research output: Contribution to journalArticle

  31. 2010
  32. Function of an implanted tissue glucose sensor for more than 1 year in animals

    David A Gough, Lucas S Kumosa, Timothy L Routh, Joe T Lin & Joseph Y Lucisano, 2010 Jul 28, In : Science Translational Medicine. 2, 42, p. 1-8 42ra53.

    Research output: Contribution to journalArticle

  33. Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants

    Marios Politis, Kit Wu, Clare Loane, Niall P. Quinn, David J. Brooks, Stig Rehncrona, Anders Björklund, Olle Lindvall & Paola Piccini, 2010, In : Science Translational Medicine. 2, 38

    Research output: Contribution to journalArticle

  34. 2009