Airway Inflammation and Immunology

Organisational unit: Research group

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  1. 2020
  2. Clinical characteristics of the BREATHE cohort–a real-life study on patients with asthma and COPD

    Backer, V., Klein, D. K., Bodtger, U., Romberg, K., Porsbjerg, C., Erjefält, J. S., Kristiansen, K., Xu, R., Silberbrandt, A., Frøssing, L., Hvidtfeldt, M., Obling, N., Jarenbäck, L., Nasr, A., Tufvesson, E., Mori, M., Winther-Jensen, M., Karlsson, L., Nihlén, U., Veje Flintegaard, T. & 1 others, Leif Bjermer, 2020 Mar 17, In : European clinical respiratory journal. 7, 1, 1736934.

    Research output: Contribution to journalArticle

  3. Basophil sensitivity reflects long-term clinical outcome of subcutaneous immunotherapy in grass pollen-allergic patients

    Schmid, J. M., Würtzen, P. A., Premkumar Siddhuraj, Jogdand, P., Petersen, C. G., Dahl, R., Jonas S. Erjefält & Hoffmann, H. J., 2020 Mar 7, In : Allergy: European Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  4. Eosinophils, basophils, and type 2 immune microenvironments in COPD-affected lung tissue

    Jogdand, P., Premkumar Siddhuraj, Mori, M., Caroline Sanden, Jönsson, J., Walls, A. F., Kearley, J., Humbles, A. A., Kolbeck, R., Leif Bjermer, Newbold, P. & Jonas S. Erjefält, 2020, In : European Respiratory Journal. 55, 4

    Research output: Contribution to journalArticle

  5. 2019
  6. IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation

    Allinne, J., Scott, G., Lim, W. K., Birchard, D., Jonas S. Erjefält, Caroline Sandén, Ben, L. H., Agrawal, A., Kaur, N., Kim, J. H., Kamat, V., Fury, W., Huang, T., Stahl, N., Yancopoulos, G. D., Murphy, A. J., Sleeman, M. A. & Orengo, J. M., 2019 Dec, In : Journal of Allergy and Clinical Immunology. 144, 6, p. 1624-1637 24 p.

    Research output: Contribution to journalArticle

  7. Bronchoscopic mucosal cryobiopsies as a method for studying airway disease

    Hvidtfeldt, M., Pulga, A., Hostrup, M., Caroline Sanden, Mori, M., Daisy Bornesund, Larsen, K. R., Jonas S. Erjefält & Porsbjerg, C., 2019 Jan, In : Clinical and Experimental Allergy. 49, 1, p. 27-34

    Research output: Contribution to journalArticle

  8. Osteopontin protects against lung injury caused by extracellular histones

    Kasetty, G., Praveen Papareddy, Ravi K.V. Bhongir, Mohamad N. Ali, Mori, M., Wygrecka, M., Jonas S. Erjefält, Hultgårdh-Nilsson, A., Palmberg, L., Heiko Herwald & Arne Egesten, 2019 Jan, In : Mucosal Immunology. 12, 1, p. 39-50

    Research output: Contribution to journalArticle

  9. IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity

    Ravanetti, L., Dijkhuis, A., Dekker, T., Sabogal Pineros, Y. S., Ravi, A., Dierdorp, B. S., Jonas S. Erjefält, Mori, M., Pavlidis, S., Adcock, I. M., Rao, N. L. & Lutter, R., 2019, In : Journal of Allergy and Clinical Immunology. 143, 4, p. 1355-1370.e16

    Research output: Contribution to journalArticle

  10. 2018
  11. Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

    Scott, I. C., Majithiya, J. B., Caroline Sanden, Thornton, P., Sanders, P. N., Moore, T., Guscott, M., Corkill, D. J., Jonas S. Erjefält & Cohen, E. S., 2018 Dec 1, In : Scientific Reports. 8, 1, 3363.

    Research output: Contribution to journalArticle

  12. Distal respiratory tract viral infections in young children trigger a marked increase in alveolar mast cells

    Cecilia K Andersson, Shikhagaie, M., Mori, M., Al-Garawi, A., Reed, J. L., Humbles, A. A., Welliver, R., Mauad, T., Leif Bjermer, Jordana, M. & Jonas S Erjefält, 2018 Oct, In : ERJ Open Research. 4, 4

    Research output: Contribution to journalArticle

  13. CD103 + CD11b + mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin

    Flores-Langarica, A., Müller Luda, K., Persson, E. K., Cook, C. N., Bobat, S., Marshall, J. L., Dahlgren, M. W., Hägerbrand, K., Toellner, K. M., Goodall, M. D., Withers, D. R., Henderson, I. R., B. Johansson Lindbom, Cunningham, A. F. & W. W. Agace, 2018 May 1, In : Mucosal Immunology. 11, 3, p. 681-692 12 p.

    Research output: Contribution to journalArticle

  14. 2017
  15. Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha I-antitrypsin deficiency

    Esquinas, C., Janciauskiene, S., Gonzalo, R., de Xaxars, G. M., Beata Olejnicka, Belmonte, I., Barrecheguren, M., Rodriguez, E., Nuñez, A., Rodriguez-Frias, F. & Miravitlles, M., 2017 Nov 29, In : International Journal of COPD. 12, p. 3381-3390 10 p.

    Research output: Contribution to journalArticle

  16. IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD

    Briend, E., Ferguson, G. J., Mori, M., Damera, G., Stephenson, K., Karp, N. A., Sethi, S., Ward, C. K., Sleeman, M. A., Jonas S. Erjefält & Finch, D. K., 2017 Aug 22, In : Respiratory Research. 18, 1, 159.

    Research output: Contribution to journalArticle

  17. Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

    Shikhagaie, M. M., Björklund, Å. K., Mjösberg, J., Jonas S. Erjefält, Cornelissen, A. S., Ros, X. R., Bal, S. M., Koning, J. J., Mebius, R. E., Mori, M., Bruchard, M., Blom, B. & Spits, H., 2017 Feb 14, In : Cell Reports. 18, 7, p. 1761-1773 13 p.

    Research output: Contribution to journalArticle

  18. Broad Th2 neutralization and anti-inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis

    Caroline Sanden, Mori, M., Jogdand, P., Jönsson, J., Krishnan, R., Wang, X. & Jonas S. Erjefält, 2017, In : Immunity, Inflammation and Disease. 5, 3, p. 300-309

    Research output: Contribution to journalArticle

  19. Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers

    Forkel, M., Berglin, L., Kekäläinen, E., Carlsson, A., Svedin, E., Michaëlsson, J., Nagasawa, M., Jonas S. Erjefält, Mori, M., Flodström-Tullberg, M., Bergquist, A., Ljunggren, H-G., Westgren, M., Lindforss, U., Friberg, D., Jorns, C., Ellis, E., Björkström, N. K. & Mjösberg, J., 2017, In : European Journal of Immunology. 47, 8, p. 1280-1294 15 p.

    Research output: Contribution to journalArticle

  20. Effectiveness of bronchial thermoplasty in patients with severe refractory asthma: Clinical and histopathologic correlations

    Pretolani, M., Bergqvist, A., Thabut, G., Dombret, M. C., Knapp, D., Hamidi, F., Alavoine, L., Taillé, C., Chanez, P., Jonas S. Erjefält & Aubier, M., 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1176-1185

    Research output: Contribution to journalArticle

  21. Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome

    Sverrild, A., Kiilerich, P., Brejnrod, A., Pedersen, R., Porsbjerg, C., Bergqvist, A., Jonas S. Erjefält, Kristiansen, K. & Backer, V., 2017, In : Journal of Allergy and Clinical Immunology. 140, 2, p. 407-417.e11

    Research output: Contribution to journalArticle

  22. Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF

    Roos, A. B., Mori, M., Gura, H. K., Lorentz, A., Leif Bjermer, Hoffmann, H-J., Jonas S. Erjefält & Stampfli, M. R., 2017, In : Respiratory Research. 18, 1, 48.

    Research output: Contribution to journalLetter

  23. 2016
  24. IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

    Luda, K. M., Thorsten Joeris, Persson, E. K., Rivollier, A., Demiri, M., Sitnik, K. M., Pool, L., Holm, J. B., Melo-Gonzalez, F., Richter, L., Lambrecht, B. N., Kristiansen, K., Travis, M. A., Svensson-Frej, M., Knut Kotarsky & William W. Agace, 2016 Apr 19, In : Immunity. 44, 4, p. 860-874 15 p.

    Research output: Contribution to journalArticle

  25. Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.

    Sverrild, A., Bergqvist, A., Baines, K. J., Porsbjerg, C., Cecilia Andersson, Thomsen, S. F., Hoffmann, H. J., Gibson, P., Jonas Erjefält & Backer, V., 2016, In : Clinical and Experimental Allergy. 46, 2, p. 288-297

    Research output: Contribution to journalArticle

  26. IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

    Bal, S. M., Bernink, J. H., Nagasawa, M., Groot, J., Shikhagaie, M. M., Golebski, K., Van Drunen, C. M., Lutter, R., Jonkers, R. E., Hombrink, P., Bruchard, M., Villaudy, J., Munneke, J. M., Fokkens, W. J., Jonas S Erjefält, Spits, H. & Ros, X. R., 2016, In : Nature Immunology. 17, 6, p. 636-645

    Research output: Contribution to journalArticle

  27. IL-33 is related to innate immune activation and sensitization to HDM in mild steroid-free asthma.

    Porsbjerg, C., Baines, K., Gibson, P., Bergqvist, A., Jonas Erjefält, Sverrild, A. & Backer, V., 2016, In : Clinical and Experimental Allergy. 46, p. 564-574

    Research output: Contribution to journalArticle

  28. Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

    Silver, J. S., Kearley, J., Copenhaver, A. M., Caroline Sanden, Mori, M., Yu, L., Pritchard, G. H., Berlin, A. A., Hunter, C. A., Bowler, R., Jonas Erjefält, Kolbeck, R. & Humbles, A. A., 2016, In : Nature Immunology. 17, 6, p. 626-635

    Research output: Contribution to journalArticle

  29. Osteopontin binds and modulate functions of eosinophil-recruiting chemokines.

    Gela, A., Kasetty, G., Mörgelin, M., Bergqvist, A., Jonas Erjefält, Pease, J. E. & Arne Egesten, 2016, In : Allergy. 71, 1, p. 58-67

    Research output: Contribution to journalArticle

  30. Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics.

    Gela, A., Ravi Bhongir, Mori, M., Keenan, P., Mörgelin, M., Jonas Erjefält, Heiko Herwald, Arne Egesten & Kasetty, G., 2016, In : PLoS ONE. 11, 1, e0146192.

    Research output: Contribution to journalArticle

  31. The neutrophil-recruiting chemokine GCP-2/CXCL6 is expressed in cystic fibrosis airways and retains its functional properties after binding to extracellular DNA.

    Jovic, S., Helena Linge, Shikhagaie, M., Olin, A., Lannefors, L., Jonas Erjefält, Mörgelin, M. & Arne Egesten, 2016, In : Mucosal Immunology. 9, 1, p. 112-123

    Research output: Contribution to journalArticle

  32. 2015
  33. Alveolar T-helper type-2 immunity in atopic asthma is associated with poor clinical control

    Bergqvist, A., Cecilia Andersson, Mori, M., Walls, A. F., Leif Bjermer & Jonas Erjefält, 2015, In : Clinical Science. 128, 1, p. 47-56

    Research output: Contribution to journalArticle

  34. A major population of mucosal memory CD4(+) T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality.

    Holmkvist, P., Roepstorff, K., Uronen-Hansson, H., Caroline Sandén, Gudjonsson, S., Oliver Hultman Patschan, Olof Grip, Marsal, J., Artur Schmidtchen, Hornum, L., Jonas Erjefält, Håkansson, K. & William Agace, 2015, In : Mucosal Immunology. 8, 3, p. 545-558

    Research output: Contribution to journalArticle

  35. Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection.

    Kearley, J., Silver, J. S., Caroline Sandén, Liu, Z., Berlin, A. A., White, N., Mori, M., Pham, T-H., Ward, C. K., Criner, G. J., Marchetti, N., Mustelin, T., Jonas Erjefält, Kolbeck, R. & Humbles, A. A., 2015, In : Immunity. 42, 3, p. 566-579

    Research output: Contribution to journalArticle

  36. Immunopathological and Structural Alterations in Difficult to Control Asthma

    Bergqvist, A., 2015, Department of Respiratory Medicine and Allergology, Lund University. 70 p.

    Research output: ThesisDoctoral Thesis (compilation)

  37. Interleukin-17A Promotes Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

    Roos, A., Sethi, S., Nikota, J., Wrona, C. T., Dorrington, M. G., Caroline Sandén, Bauer, C. M., Shen, P., Bowdish, D., Stevenson, C. S., Jonas Erjefält & Stampfli, M. R., 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 4, p. 428-437

    Research output: Contribution to journalArticle

  38. Osteopontin is increased in cystic fibrosis and can skew the functional balance between ELR-positive and ELR-negative CXC-chemokines.

    Jovic, S., Shikhagaie, M., Mörgelin, M., Jonas Erjefält, Kjellström, S. & Arne Egesten, 2015, In : Journal of Cystic Fibrosis. 14, 4, p. 453-463

    Research output: Contribution to journalArticle

  39. Small airway epithelial-C/EBPβ is increased in patients with advanced COPD.

    Mori, M., Leif Bjermer, Jonas Erjefält, Stampfli, M. R. & Roos, A., 2015, In : Respiratory Research. 16, 133.

    Research output: Contribution to journalArticle

  40. The polyamine spermine promotes survival and activation of human eosinophils.

    Ilmarinen, P., Moilanen, E., Jonas Erjefält & Kankaanranta, H., 2015, In : Journal of Allergy and Clinical Immunology. 136, 2, p. 482

    Research output: Contribution to journalLetter

  41. 2014
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