Airway Inflammation and Immunology

Organisational unit: Research group

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  1. 2019
  2. Bronchoscopic mucosal cryobiopsies as a method for studying airway disease

    Hvidtfeldt, M., Pulga, A., Hostrup, M., Caroline Sanden, Michiko Mori, Daisy Bornesund, Larsen, K. R., Jonas S. Erjefält & Porsbjerg, C., 2019 Jan, In : Clinical and Experimental Allergy. 49, 1, p. 27-34

    Research output: Contribution to journalArticle

  3. Osteopontin protects against lung injury caused by extracellular histones

    Kasetty, G., Praveen Papareddy, Ravi K.V. Bhongir, Mohamad N. Ali, Michiko Mori, Wygrecka, M., Jonas S. Erjefält, Hultgårdh-Nilsson, A., Palmberg, L., Heiko Herwald & Arne Egesten, 2019 Jan, In : Mucosal Immunology. 12, 1, p. 39-50

    Research output: Contribution to journalArticle

  4. IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity

    Ravanetti, L., Dijkhuis, A., Dekker, T., Sabogal Pineros, Y. S., Ravi, A., Dierdorp, B. S., Jonas S. Erjefält, Michiko Mori, Pavlidis, S., Adcock, I. M., Rao, N. L. & Lutter, R., 2019, In : Journal of Allergy and Clinical Immunology. 143, 4, p. 1355-1370.e16

    Research output: Contribution to journalArticle

  5. 2018
  6. Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

    Scott, I. C., Majithiya, J. B., Caroline Sanden, Thornton, P., Sanders, P. N., Moore, T., Guscott, M., Corkill, D. J., Jonas S. Erjefält & Cohen, E. S., 2018 Dec 1, In : Scientific Reports. 8, 1, 3363.

    Research output: Contribution to journalArticle

  7. Distal respiratory tract viral infections in young children trigger a marked increase in alveolar mast cells

    Cecilia K Andersson, Shikhagaie, M., Michiko Mori, Al-Garawi, A., Reed, J. L., Humbles, A. A., Welliver, R., Mauad, T., Leif Bjermer, Jordana, M. & Jonas S Erjefält, 2018 Oct, In : ERJ Open Research. 4, 4

    Research output: Contribution to journalArticle

  8. CD103 + CD11b + mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin

    Flores-Langarica, A., Müller Luda, K., Persson, E. K., Cook, C. N., Bobat, S., Marshall, J. L., Dahlgren, M. W., Hägerbrand, K., Toellner, K. M., Goodall, M. D., Withers, D. R., Henderson, I. R., B. Johansson Lindbom, Cunningham, A. F. & W. W. Agace, 2018 May 1, In : Mucosal Immunology. 11, 3, p. 681-692 12 p.

    Research output: Contribution to journalArticle

  9. 2017
  10. Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha I-antitrypsin deficiency

    Esquinas, C., Janciauskiene, S., Gonzalo, R., de Xaxars, G. M., Beata Olejnicka, Belmonte, I., Barrecheguren, M., Rodriguez, E., Nuñez, A., Rodriguez-Frias, F. & Miravitlles, M., 2017 Nov 29, In : International Journal of COPD. 12, p. 3381-3390 10 p.

    Research output: Contribution to journalArticle

  11. IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD

    Briend, E., Ferguson, G. J., Michiko Mori, Damera, G., Stephenson, K., Karp, N. A., Sethi, S., Ward, C. K., Sleeman, M. A., Jonas S. Erjefält & Finch, D. K., 2017 Aug 22, In : Respiratory Research. 18, 1, 159.

    Research output: Contribution to journalArticle

  12. Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

    Shikhagaie, M. M., Björklund, Å. K., Mjösberg, J., Jonas S. Erjefält, Cornelissen, A. S., Ros, X. R., Bal, S. M., Koning, J. J., Mebius, R. E., Michiko Mori, Bruchard, M., Blom, B. & Spits, H., 2017 Feb 14, In : Cell Reports. 18, 7, p. 1761-1773 13 p.

    Research output: Contribution to journalArticle

  13. Broad Th2 neutralization and anti-inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis

    Caroline Sanden, Michiko Mori, Jogdand, P., Jönsson, J., Krishnan, R., Wang, X. & Jonas S. Erjefält, 2017, In : Immunity, Inflammation and Disease. 5, 3, p. 300-309

    Research output: Contribution to journalArticle

  14. Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers

    Forkel, M., Berglin, L., Kekäläinen, E., Carlsson, A., Svedin, E., Michaëlsson, J., Nagasawa, M., Jonas S. Erjefält, Michiko Mori, Flodström-Tullberg, M., Bergquist, A., Ljunggren, H-G., Westgren, M., Lindforss, U., Friberg, D., Jorns, C., Ellis, E., Björkström, N. K. & Mjösberg, J., 2017, In : European Journal of Immunology. 47, 8, p. 1280-1294 15 p.

    Research output: Contribution to journalArticle

  15. Effectiveness of bronchial thermoplasty in patients with severe refractory asthma: Clinical and histopathologic correlations

    Pretolani, M., Bergqvist, A., Thabut, G., Dombret, M. C., Knapp, D., Hamidi, F., Alavoine, L., Taillé, C., Chanez, P., Jonas S. Erjefält & Aubier, M., 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1176-1185

    Research output: Contribution to journalArticle

  16. Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome

    Sverrild, A., Kiilerich, P., Brejnrod, A., Pedersen, R., Porsbjerg, C., Bergqvist, A., Jonas S. Erjefält, Kristiansen, K. & Backer, V., 2017, In : Journal of Allergy and Clinical Immunology. 140, 2, p. 407-417.e11

    Research output: Contribution to journalArticle

  17. Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF

    Roos, A. B., Michiko Mori, Gura, H. K., Lorentz, A., Leif Bjermer, Hoffmann, H-J., Jonas S. Erjefält & Stampfli, M. R., 2017, In : Respiratory Research. 18, 1, 48.

    Research output: Contribution to journalLetter

  18. 2016
  19. IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

    Luda, K. M., Thorsten Joeris, Persson, E. K., Rivollier, A., Demiri, M., Sitnik, K. M., Lieneke Pool, Holm, J. B., Melo-Gonzalez, F., Richter, L., Lambrecht, B. N., Kristiansen, K., Travis, M. A., Svensson-Frej, M., Knut Kotarsky & William W. Agace, 2016 Apr 19, In : Immunity. 44, 4, p. 860-874 15 p.

    Research output: Contribution to journalArticle

  20. Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.

    Sverrild, A., Bergqvist, A., Baines, K. J., Porsbjerg, C., Cecilia Andersson, Thomsen, S. F., Hoffmann, H. J., Gibson, P., Jonas Erjefält & Backer, V., 2016, In : Clinical and Experimental Allergy. 46, 2, p. 288-297

    Research output: Contribution to journalArticle

  21. IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

    Bal, S. M., Bernink, J. H., Nagasawa, M., Groot, J., Shikhagaie, M. M., Golebski, K., Van Drunen, C. M., Lutter, R., Jonkers, R. E., Hombrink, P., Bruchard, M., Villaudy, J., Munneke, J. M., Fokkens, W. J., Jonas S Erjefält, Spits, H. & Ros, X. R., 2016, In : Nature Immunology. 17, 6, p. 636-645

    Research output: Contribution to journalArticle

  22. IL-33 is related to innate immune activation and sensitization to HDM in mild steroid-free asthma.

    Porsbjerg, C., Baines, K., Gibson, P., Bergqvist, A., Jonas Erjefält, Sverrild, A. & Backer, V., 2016, In : Clinical and Experimental Allergy. 46, p. 564-574

    Research output: Contribution to journalArticle

  23. Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

    Silver, J. S., Kearley, J., Copenhaver, A. M., Caroline Sanden, Michiko Mori, Yu, L., Pritchard, G. H., Berlin, A. A., Hunter, C. A., Bowler, R., Jonas Erjefält, Kolbeck, R. & Humbles, A. A., 2016, In : Nature Immunology. 17, 6, p. 626-635

    Research output: Contribution to journalArticle

  24. Osteopontin binds and modulate functions of eosinophil-recruiting chemokines.

    Gela, A., Kasetty, G., Mörgelin, M., Bergqvist, A., Jonas Erjefält, Pease, J. E. & Arne Egesten, 2016, In : Allergy. 71, 1, p. 58-67

    Research output: Contribution to journalArticle

  25. Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics.

    Gela, A., Ravi Bhongir, Michiko Mori, Keenan, P., Mörgelin, M., Jonas Erjefält, Heiko Herwald, Arne Egesten & Kasetty, G., 2016, In : PLoS ONE. 11, 1, e0146192.

    Research output: Contribution to journalArticle

  26. The neutrophil-recruiting chemokine GCP-2/CXCL6 is expressed in cystic fibrosis airways and retains its functional properties after binding to extracellular DNA.

    Jovic, S., Helena Linge, Shikhagaie, M., Olin, A., Lannefors, L., Jonas Erjefält, Mörgelin, M. & Arne Egesten, 2016, In : Mucosal Immunology. 9, 1, p. 112-123

    Research output: Contribution to journalArticle

  27. 2015
  28. Alveolar T-helper type-2 immunity in atopic asthma is associated with poor clinical control

    Bergqvist, A., Cecilia Andersson, Michiko Mori, Walls, A. F., Leif Bjermer & Jonas Erjefält, 2015, In : Clinical Science. 128, 1, p. 47-56

    Research output: Contribution to journalArticle

  29. A major population of mucosal memory CD4(+) T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality.

    Holmkvist, P., Roepstorff, K., Uronen-Hansson, H., Caroline Sandén, Gudjonsson, S., Oliver Hultman Patschan, Olof Grip, Marsal, J., Artur Schmidtchen, Hornum, L., Jonas Erjefält, Håkansson, K. & William Agace, 2015, In : Mucosal Immunology. 8, 3, p. 545-558

    Research output: Contribution to journalArticle

  30. Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection.

    Kearley, J., Silver, J. S., Caroline Sandén, Liu, Z., Berlin, A. A., White, N., Michiko Mori, Pham, T-H., Ward, C. K., Criner, G. J., Marchetti, N., Mustelin, T., Jonas Erjefält, Kolbeck, R. & Humbles, A. A., 2015, In : Immunity. 42, 3, p. 566-579

    Research output: Contribution to journalArticle

  31. Immunopathological and Structural Alterations in Difficult to Control Asthma

    Bergqvist, A., 2015, Department of Respiratory Medicine and Allergology, Lund University. 70 p.

    Research output: ThesisDoctoral Thesis (compilation)

  32. Interleukin-17A Promotes Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

    Roos, A., Sethi, S., Nikota, J., Wrona, C. T., Dorrington, M. G., Caroline Sandén, Bauer, C. M., Shen, P., Bowdish, D., Stevenson, C. S., Jonas Erjefält & Stampfli, M. R., 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 4, p. 428-437

    Research output: Contribution to journalArticle

  33. Osteopontin is increased in cystic fibrosis and can skew the functional balance between ELR-positive and ELR-negative CXC-chemokines.

    Jovic, S., Shikhagaie, M., Mörgelin, M., Jonas Erjefält, Kjellström, S. & Arne Egesten, 2015, In : Journal of Cystic Fibrosis. 14, 4, p. 453-463

    Research output: Contribution to journalArticle

  34. Small airway epithelial-C/EBPβ is increased in patients with advanced COPD.

    Michiko Mori, Leif Bjermer, Jonas Erjefält, Stampfli, M. R. & Roos, A., 2015, In : Respiratory Research. 16, 133.

    Research output: Contribution to journalArticle

  35. The polyamine spermine promotes survival and activation of human eosinophils.

    Ilmarinen, P., Moilanen, E., Jonas Erjefält & Kankaanranta, H., 2015, In : Journal of Allergy and Clinical Immunology. 136, 2, p. 482

    Research output: Contribution to journalLetter

  36. 2014
  37. Elevated Exhaled Nitric Oxide in Allergen-Provoked Asthma Is Associated with Airway Epithelial iNOS.

    Roos, A., Michiko Mori, Grönneberg, R., Osterlund, C., Claesson, H-E., Wahlström, J., Grunewald, J., Eklund, A., Jonas Erjefält, Lundberg, J. O. & Nord, M., 2014, In : PLoS ONE. 9, 2, e90018.

    Research output: Contribution to journalArticle

  38. Expression of MIG/CXCL9 in Cystic Fibrosis and Modulation of Its Activities by Elastase of Pseudomonas aeruginosa.

    Jovic, S., Shikhagaie, M., Mörgelin, M., Kjellström, S., Jonas Erjefält, Olin, A., Inga-Maria Frick & Arne Egesten, 2014, In : Journal of Innate Immunity. 6, 6, p. 846-859

    Research output: Contribution to journalArticle

  39. Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo.

    Chu, D. K., Jimenez-Saiz, R., Verschoor, C. P., Walker, T. D., Goncharova, S., Llop-Guevara, A., Shen, P., Gordon, M. E., Barra, N. G., Bassett, J. D., Kong, J., Fattouh, R., McCoy, K. D., Bowdish, D. M., Jonas Erjefält, Pabst, O., Humbles, A. A., Kolbeck, R., Waserman, S. & Jordana, M., 2014, In : Journal of Experimental Medicine. 211, 8, p. 1657-1672

    Research output: Contribution to journalArticle

  40. Kinin-Stimulated B1 Receptor Signaling Depends on Receptor Endocytosis Whereas B2 Receptor Signaling Does Not.

    Enquist, J., Caroline Sandén, Skröder, C., Mathis, S. A. & Fredrik Leeb-Lundberg, 2014, In : Neurochemical Research. 39, 6, p. 1037-1047

    Research output: Contribution to journalArticle

  41. Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma.

    Shikhagaie, M., Cecilia Andersson, Michiko Mori, Kortekaas Krohn, I., Bergqvist, A., Dahl, R., Eva Ekblad, Hoffmann, H. J., Leif Bjermer & Jonas Erjefält, 2014, In : Clinical and Experimental Allergy. 44, 2, p. 184-196

    Research output: Contribution to journalArticle

  42. Oral iodinated activated charcoal improves lung function in patients with COPD.

    Skogvall, S., Jonas Erjefält, Olin, A., Jaro Ankerst & Leif Bjermer, 2014, In : Respiratory Medicine. 108, 6, p. 905-909

    Research output: Contribution to journalArticle

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