Antioxidation medicine

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Infectious Medicine


  • Oxidation, antioxidation, inflammatory diseases, alpha-1-microglobulin


Antioxidation medicine describes how the body is protected against unwanted oxidation. ’Oxidation’ is a name for the chemical reactions between oxygen and the molecules of the body. Protection molecules, ’antioxidants’ are produced by the body to prevent the oxidation reactions from becoming violent. Without antioxidation control our bodies would quickly decay similar to a log fire or a decomposing apple. Antioxidants are also essential to protect bystander tissues during inflammatory diseases, and ensure that humans can stay healthy during a life-span of more than 70 years. Perhaps the most important human antioxidant is called alpha-1-microglobulin (A1M). Our research is focussed on A1M. We are studying structure and functions of this protein and also trying to develop disease treatments by using A1M. Together with clinical researchers and industry we are now working with preeclampsia, brain damage, kidney damage, radiation cancer therapy, retinal detachment and atherosclerosis.

Recent research outputs

Romantsik, O., Alex Adusei Agyemang, Sveinsdóttir, S., Rutardóttir, S., Holmqvist, B., Magnus Cinthio, Mörgelin, M., Gumus, G., Karlsson, H., Stefan R. Hansson, Bo Åkerström, David Ley & Magnus Gram, 2019 Jun 7, In : Journal of Neuroinflammation. 16, 1, 122.

Research output: Contribution to journalArticle

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