Breast and Ovarian Cancer Genomics

Organisational unit: Research group

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  1. 2019
  2. Afadin cooperates with Claudin-2 to promote breast cancer metastasis

    Tabariès, S., McNulty, A., Ouellet, V., Annis, M. G., Dessureault, M., Vinette, M., Hachem, Y., Lavoie, B., Omeroglu, A., Simon, H. G., Walsh, L. A., Siker Kimbung, Ingrid Hedenfalk & Siegel, P. M., 2019, In : Genes & Development. 33, 3-4, p. 180-193 14 p.

    Research output: Contribution to journalArticle

  3. A targeted mass spectrometry strategy for developing proteomic biomarkers: a case study of epithelial ovarian cancer

    Huttenhain, R., Choi, M., Laura Martin de la Fuente, Oehl, K., Chang, C-Y., Zimmermann, A-K., Malander, S., Hakan Olsson, Surinova, S., Clough, T., Heinzelmann-Schwarz, V., Wild, P. J., Dinulescu, D., Emma Niméus, Vitek, O. & Aebersold, R., 2019, In : Molecular and Cellular Proteomics. 18, 9, p. 1836-1850

    Research output: Contribution to journalArticle

  4. Hunting a Silent Killer. Biomolecular Approaches in Ovarian Cancer

    Nicolai Arildsen, 2019, Lund: Lund University, Faculty of Medicine. 100 p.

    Research output: ThesisDoctoral Thesis (compilation)

  5. 2018
  6. Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

    Severson, T. M., Kim, Y., Joosten, S. E. P., Schuurman, K., Van Der Groep, P., Moelans, C. B., Ter Hoeve, N. D., Manson, Q. F., Martens, J. W., Van Deurzen, C. H. M., Barbe, E., Ingrid Hedenfalk, Bult, P., Smit, V. T. H. B. M., Linn, S. C., Van Diest, P. J., Wessels, L. & Zwart, W., 2018 Dec 1, In : Nature Communications. 9, 1, 482.

    Research output: Contribution to journalArticle

  7. Assessment of early response biomarkers in relation to long-term survival in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy plus bevacizumab: Results from the Phase II PROMIX trial

    Siker Kimbung, Markholm, I., Bjöhle, J., Lekberg, T., Wachenfeldt, V. A., Azavedo, E., Saracco, A., Hellström, M., Srinivas Veerla, Paquet, E., Pär Ola Bendahl, Mårten Fernö, Bergh, J., Niklas Loman, Hatschek, T. & Ingrid Hedenfalk, 2018, In : International Journal of Cancer. 142, 3, p. 618-628

    Research output: Contribution to journalArticle

  8. Ghrelin expression is associated with a favorable outcome in male breast cancer

    Grönberg, M., Nilsson, C., Markholm, I., Ingrid Hedenfalk, Blomqvist, C., Holmberg, L., Tiensuu Janson, E. & Fjällskog, M. L., 2018, In : Scientific Reports. 8, 1, 13586.

    Research output: Contribution to journalArticle

  9. 2017
  10. An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

    Palazon, A., Tyrakis, P. A., Macias, D., Veliça, P., Rundqvist, H., Fitzpatrick, S., Vojnovic, N., Phan, A. T., Niklas Loman, Ingrid Hedenfalk, Hatschek, T., Lövrot, J., Foukakis, T., Goldrath, A. W., Bergh, J. & Johnson, R. S., 2017 Nov 13, In : Cancer Cell. 32, 5, p. 669-683.e5

    Research output: Contribution to journalArticle

  11. Involvement of chromatin remodeling genes and the Rho GTPases RhoB and CDC42 in ovarian clear cell carcinoma

    Nicolai Skovbjerg Arildsen, Jenny Maria Jönsson, Bartuma, K., Anna Ebbesson, Westbom-Fremer, S., Måsbäck, A., Malander, S., Mef Nilbert & Ingrid A. Hedenfalk, 2017 May 29, In : Frontiers in Oncology. 7, MAY, p. 1-11 109.

    Research output: Contribution to journalArticle

  12. A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer

    Humphries, M. P., Rajan, S. S., Droop, A., Suleman, C. A. B., Carbone, C., Nilsson, C., Honarpisheh, H., Cserni, G., Dent, J., Fulford, L., Jordan, L. B., Jones, J. L., Kanthan, R., Litwiniuk, M., Di Benedetto, A., Mottolese, M., Provenzano, E., Shousha, S., Stephens, M., Walker, R. A. & 12 othersKulka, J., Ellis, I. O., Jeffery, M., Thygesen, H. H., Cappelletti, V., Daidone, M. G., Ingrid A. Hedenfalk, Fjällskog, M-L., Melisi, D., Stead, L. F., Shaaban, A. M. & Speirs, V., 2017 May 15, In : Clinical Cancer Research. 23, 10, p. 2575-2583 9 p.

    Research output: Contribution to journalArticle

  13. 2016
  14. Transcriptional profiling of breast cancer metastases identifies liver metastasis-selective genes associated with adverse outcome in luminal A primary breast cancer.

    Siker Kimbung, Johansson, I., Danielsson, A., Srinivas Veerla, Brage, S. E., Frostvik Stolt, M., Skoog, L., Carlsson, L., Einbeigi, Z., Lidbrink, E., Linderholm, B. K., Niklas Loman, Per Malmström, Söderberg, M., Walz, T. M., Fernö, M., Hatschek, T. & Ingrid Hedenfalk, 2016, In : Clinical Cancer Research. 22, 1, p. 146-157

    Research output: Contribution to journalArticle

  15. 2015
  16. Clinical and molecular complexity of breast cancer metastases.

    Siker Kimbung, Niklas Loman & Ingrid Hedenfalk, 2015, In : Seminars in Cancer Biology. 35, p. 85-95

    Research output: Contribution to journalReview article

  17. Contrasting breast cancer molecular subtypes across serial tumor progression stages: biological and prognostic implications.

    Siker Kimbung, Kovács, A., Danielsson, A., Pär-Ola Bendahl, Lövgren, K., Stolt, M. F., Tobin, N. P., Lindström, L., Bergh, J., Einbeigi, Z., Mårten Fernö, Hatschek, T. & Ingrid Hedenfalk, 2015, In : Oncotarget. 6, 32, p. 33306-33318

    Research output: Contribution to journalArticle

  18. Sex Steroid Hormone Receptor Expression Affects Ovarian Cancer Survival.

    Jenny-Maria Jönsson, Nicolai Arildsen, Malander, S., Måsbäck, A., Linda Werner Hartman, Mef Nilbert & Ingrid Hedenfalk, 2015, In : Translational Oncology. 8, 5, p. 424-433

    Research output: Contribution to journalArticle

  19. 2014
  20. Molecular profiling of male breast cancer - Lost in translation?

    Johansson, I., Killander, F., Linderholm, B. & Ingrid Hedenfalk, 2014, In : International Journal of Biochemistry & Cell Biology. 53, May 16, p. 526-535

    Research output: Contribution to journalReview article

  21. Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

    Jenny-Maria Jönsson, Johansson, I., Dominguez, M., Siker Kimbung, Mats Jönsson, Bonde, J. H., Päivi Kannisto, Måsbäck, A., Malander, S., Mef Nilbert & Ingrid Hedenfalk, 2014, In : PLoS ONE. 9, 9, e107643.

    Research output: Contribution to journalArticle

  22. 2013
  23. The Landscape of Candidate Driver Genes Differs between Male and Female Breast Cancer.

    Johansson, I., Markus Ringnér & Ingrid Hedenfalk, 2013, In : PLoS ONE. 8, 10, e78299.

    Research output: Contribution to journalArticle

  24. 2012
  25. Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition.

    Siker Kimbung, Biskup, E., Johansson, I., Kristina Aaltonen, Ottosson-Wadlund, A., Sofia Gruvberger, Cunliffe, H., Fadeel, B., Niklas Loman, Berglund, P. & Ingrid Hedenfalk, 2012, In : Cancer Letters. 319, 2, p. 232-241

    Research output: Contribution to journalArticle

  26. Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker

    Johansson, I., Nilsson, C., Berglund, P., Martin Lauss, Markus Ringnér, Håkan Olsson, Luts, L., Sim, E., Thorstensson, S., Fjallskog, M-L. & Ingrid Hedenfalk, 2012, In : Breast Cancer Research. 14, 1, R31.

    Research output: Contribution to journalArticle

  27. Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

    Orr, N., Lemnrau, A., Cooke, R., Fletcher, O., Tomczyk, K., Jones, M., Johnson, N., Lord, C. J., Mitsopoulos, C., Zvelebil, M., McDade, S. S., Buck, G., Blancher, C., Trainer, A. H., James, P. A., Bojesen, S. E., Bokmand, S., Nevanlinna, H., Mattson, J., Friedman, E. & 24 othersLaitman, Y., Palli, D., Masala, G., Zanna, I., Ottini, L., Giannini, G., Hollestelle, A., van den Ouweland, A. M. W., Novakovic, S., Krajc, M., Gago-Dominguez, M., Castelao, J. E., Håkan Olsson, Ingrid Hedenfalk, Easton, D. F., Pharoah, P. D. P., Dunning, A. M., Bishop, D. T., Neuhausen, S. L., Steele, L., Houlston, R. S., Garcia-Closas, M., Ashworth, A. & Swerdlow, A. J., 2012, In : Nature Genetics. 44, 11, p. 1182-1184

    Research output: Contribution to journalArticle

  28. 2011
  29. 2010
  30. 2003
  31. Molecular classification of familial non-BRCA1/BRCA2 breast cancer

    Ingrid Hedenfalk, Markus Ringnér, Ben-Dor, A., Yakhini, Z., Chen, Y., Chebil, G., Ach, R., Niklas Loman, Håkan Olsson, Meltzer, P., Åke Borg & Trent, J., 2003, In : Proceedings of the National Academy of Sciences. 100, 5, p. 2532-2537

    Research output: Contribution to journalArticle

  32. 2001
  33. Gene-expression profiles in hereditary breast cancer

    Hedenfalk, I., Duggan, D., Chen, Y., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Kallioniemi, O. P., Wilfond, B., Borg, Å., Trent, J., Raffeld, M., Yakhini, Z., Ben-Dor, A., Dougherty, E., Kononen, J., Bubendorf, L., Fehrle, W. & 6 othersPittaluga, S., S Gruvberger, N Loman, Johannsson, O., Håkan Olsson & Sauter, G., 2001 Feb 22, In : New England Journal of Medicine. 344, 8, p. 539-48 10 p.

    Research output: Contribution to journalArticle