Cardiovascular Research - Immunity and Atherosclerosis

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cardiac and Cardiovascular Systems
  • Endocrinology and Diabetes
  • Cell and Molecular Biology
  • Family Medicine


  • Atherosclerosis , fibrosis, diabetes


Atherosclerosis is a disease characterized by chronic inflammation and fibrosis of the intima of large and medium sized arteries. Atherosclerosis in the coronary arteries is the most common cause of myocardial infarction and atherosclerosis in the carotids and other major arteries supplying the brain is the major cause of stroke. Cardiovascular diseases caused by atherosclerosis is the most common cause of death and disability in the western societies. More effective risk factor intervention combined with better management of acute cardiovascular events have decreased age-related cardiovascular mortality by over 30% over the last decades. However, health problems caused by atherosclerosis are increasing as the proportion of older people in the population rises. Further advancements in the treatment of atherosclerosis requires a better understanding of the molecular disease mechanisms and development of interventions more specifically targeted towards these mechanisms.

Recent research outputs

Pontus Dunér, Ingrid Yao Mattisson, Per Fogelstrand, Lars Glise, Stacey Ruiz, Christopher Farina, Jan Borén, Jan Nilsson & Eva Bengtsson, 2021 Dec 1, In: Scientific Reports. 11, 1, 9022.

Research output: Contribution to journalArticle

S. Holm Nielsen, A. Edsfeldt, C. Tengryd, H. Gustafsson, A. C. Shore, A. Natali, F. Khan, F. Genovese, E. Bengtsson, M. Karsdal, D. J. Leeming, J. Nilsson & I. Goncalves, 2021 May 5, In: Journal of Internal Medicine.

Research output: Contribution to journalArticle

Megan Mulholland, Gabriel Jakobsson, Yu Lei, Lena Sundius, Irena Ljungcrantz, Sara Rattik, Uwe J F Tietge & Daniel Engelbertsen, 2021 Apr 24, In: Atherosclerosis. 326, p. 1-10

Research output: Contribution to journalArticle

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