Organisational unit: Research group
Research areas and keywords
UKÄ subject classification
- Parkinson disease, stroke, dementia, dystonia, ataxia
Many neurological disorders have a genetic cause or are markedly influenced by genetic factors. At the Department for Neurology, Skåne University Hospital, we examine patients with neurological disorders within research studies and elucidate contributing or causative genetic factors. Ongoing studies include patients with, for example, Parkinson disease, dystonia, ataxia, hereditary causes of dementia or stroke, with a special emphasis on kindred with familial forms of these diseases. We investigate how common the known genetic causes of neurological disorders are in Sweden. The aim of our research is to identify new gene mutations that cause these diseases and to understand how gene mutations affect cellular mechanisms. Unravelling the molecular disease mechanism lays the foundation for the development of novel therapies. We also improve strategies for clinical genetic testing and information on genetic neurological disorders to neurologists, patients and families.
Recent research outputs
Sorina Gorcenco, Vaz, F. M., Tracewska-Siemiatkowska, A., Tranebjærg, L., Cremers, F. P. M., Emil Ygland, Kicsi, J., Rendtorff, N. D., Möller, C., Kjellström, U., Sten Andréasson & Andreas Puschmann, 2019, In : Parkinsonism & Related Disorders. 61, p. 245-247 3 p.
Research output: Contribution to journal › Letter
LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing studyInternational Parkinsonism Genetics Network, Ferreira, J., Cossu, G., Lu, C-S., Meco, G., Cortelli, P., van de Berg, W. D. J. & Bonifati, V., 2018 Jul, In : The Lancet Neurology. 17, 7, p. 597-608
Research output: Contribution to journal › Article
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