Diabetes - Islet Cell Exocytosis

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  1. 2019
  2. Associations of food groups and cardiometabolic and inflammatory biomarkers - Does the meal matter?

    Schwedhelm, C., Schwingshackl, L., Agogo, G. O., Emily Sonestedt, Boeing, H. & Knüppel, S., 2019, In : British Journal of Nutrition.

    Research output: Contribution to journalArticle

  3. Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

    Anna Edlund, Mohammad Barghouth, Huhn, M., Abels, M., Jonathan Esguerra, Mollet, I., Svedin, E., Anna Wendt, Erik Renström, Enming Zhang, Nils Wierup, Scholte, B. J., Flodström-Tullberg, M. & Lena Eliasson, 2019, In : Journal of Endocrinology. 241, 1, p. 45-57

    Research output: Contribution to journalArticle

  4. In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion

    Bijkerk, R., Jonathan L S Esguerra, Ellenbroek, J. H., Au, Y. W., Hanegraaf, M. A. J., de Koning, E. J., Lena Eliasson & van Zonneveld, A. J., 2019, In : Nucleic acid therapeutics. 29, 2, p. 67-72

    Research output: Contribution to journalArticle

  5. 2018
  6. Islet microRNAs in health and type-2 diabetes

    Anna Wendt, Jonathan LS Esguerra & Lena Eliasson, 2018 Dec 1, In : Current Opinion in Pharmacology. 43, p. 46-52 7 p.

    Research output: Contribution to journalReview article

  7. N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism

    Ström, K., Morales-Alamo, D., Ottosson, F., Edlund, A., Hjort, L., Jörgensen, S. W., Almgren, P., Zhou, Y., Martin-Rincon, M., Ekman, C., Pérez-López, A., Ekström, O., Perez-Suarez, I., Mattiasson, M., De Pablos-Velasco, P., Oskolkov, N., Ahlqvist, E., Wierup, N., Eliasson, L., Vaag, A. & 6 othersLeif Groop, Karin G. Stenkula, Céline Fernandez, Calbet, J. A. L., Holmberg, H. C. & Ola Hansson, 2018 Dec 1, In : Scientific Reports. 8, 1, 3016.

    Research output: Contribution to journalArticle

  8. Abnormal structural brain connectome in individuals with preclinical Alzheimer's disease

    Joana B. Pereira, Danielle Van Westen, Erik Stomrud, Strandberg, T. O., Volpe, G., Westman, E. & Oskar Hansson, 2018 Oct 1, In : Cerebral Cortex. 28, 10, p. 3638-3649 12 p.

    Research output: Contribution to journalArticle

  9. MicroRNAs in islet hormone secretion

    Jonathan L.S. Esguerra, Mototsugu Nagao, Jones K. Ofori, Anna Wendt & Lena Eliasson, 2018 Sep 1, In : Diabetes, Obesity and Metabolism. 20, Suppl 2, p. 11-19

    Research output: Contribution to journalReview article

  10. Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques

    Lukas Tomas, Edsfeldt, A., Mollet, I. G., Perisic Matic, L., Prehn, C., Adamski, J., Paulsson-Berne, G., Hedin, U., Jan Nilsson, Eva Bengtsson, Isabel Gonçalves & Harry Björkbacka, 2018 Jun 21, In : European Heart Journal. 39, 24, p. 2301-2310

    Research output: Contribution to journalArticle

  11. Falls Predict Fractures Independently of FRAX Probability: A Meta-Analysis of the Osteoporotic Fractures in Men (MrOS) Study

    Harvey, N. C., Odén, A., Orwoll, E., Lapidus, J., Kwok, T., Magnus K. Karlsson, Björn E. Rosengren, Ljunggren, Ö., Cooper, C., McCloskey, E., Kanis, J. A., Ohlsson, C., Mellström, D. & Johansson, H., 2018 Mar, In : Journal of Bone and Mineral Research. 33, 3, p. 510-516 7 p.

    Research output: Contribution to journalArticle

  12. She is in science to stay!

    Birnir, B. & L. Eliasson, 2018, In : Acta Physiologica. 223, 1, p. e13048

    Research output: Contribution to journalDebate/Note/Editorial

  13. 2017
  14. MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles

    Salunkhe, V. A., Jones K. Ofori, Gandasi, N. R., Salö, S. A., Hansson, S., Markus E. Andersson, Anna Wendt, Barg, S., Jonathan L.S. Esguerra & Lena Eliasson, 2017 Nov 1, In : Physiological Reports. 5, 21, e13493.

    Research output: Contribution to journalArticle

  15. Glucotoxicity-induced upregulation of lincRNA GAS5 in the pancreatic islets of type 2 diabetes donors and in Goto-Kakizaki rats

    J. L. S. Esguerra, J. Ofori, M. Nagao, Fadista, J., L. Groop & L. Eliasson, 2017 Sep 1, In : Diabetologia. 60, 1 Suppl 1, p. S22-S23

    Research output: Contribution to journalPublished meeting abstract

  16. Reduced insulin secretion in a diet-induced glucose intolerance susceptible mouse model is coupled with increased CD36 and triglycerides in the beta cells

    A. Asai, M. Nagao, Tsuduki, T., Miyazawa, T., J. L. S. Esguerra, L. Eliasson, Sugihara, H. & Oikawa, S., 2017 Sep 1, p. S61.

    Research output: Contribution to conferenceAbstract

  17. Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells

    Nicholas, L. M., Valtat, B., Benavente, A. M., Andersson, L., Abels, M., Mollet, I., Jain, D., Lena Eliasson, Nils Wierup, Malin Fex & Hindrik Mulder, 2017 Jul, In : Molecular Metabolism. 6, 7, p. 651-663 13 p.

    Research output: Contribution to journalArticle

  18. Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines

    Jones K Ofori, Malm, H. A., Mollet, I. G., Lena Eliasson & Jonathan Lou S Esguerra, 2017 Jun 28, In : PeerJ. 5, 11 p., e3503.

    Research output: Contribution to journalArticle

  19. Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes

    Axelsson, A., Mahdi, T., Nenonen, H. A., Singh, T., Hänzelmann, S., Wendt, A., Bagge, A., Reinbothe, T. M., Millstein, J., Yang, X., Zhang, B., Gusmao, E. G., Shu, L., Szabat, M., Tang, Y., Wang, J., Salö, S., Eliasson, L., Artner, I., Fex, M. & 9 othersJ D Johnson, C B Wollheim, Derry, J. M. J., Mecham, B., P Spégel, H Mulder, Costa, I. G., E Zhang & Rosengren, A. H., 2017 Jun 6, In : Nature Communications. 8, p. 15652

    Research output: Contribution to journalArticle

  20. CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

    Anna Edlund, Pedersen, M. G., Andreas Lindqvist, Nils Wierup, Flodström-Tullberg, M. & Lena Eliasson, 2017 Mar 7, In : Scientific Reports. 7, p. 1-12 90.

    Research output: Contribution to journalArticle

  21. Erythropoietin and TRPV1 together in new formation

    L. Eliasson, 2017 Feb 1, In : Acta Physiologica. 219, 2, p. 341-342 2 p.

    Research output: Contribution to journalDebate/Note/Editorial

  22. Osteopontin affects insulin vesicle localization and Ca2+ homeostasis in pancreatic beta cells from female mice

    Anna Wendt, Mollet, I., Anki Knutsson, Bolmgren, V. S., Anna Hultgårdh, Maria F. Gomez & Lena Eliasson, 2017 Jan 1, In : PLoS ONE. 12, 1, e0170498.

    Research output: Contribution to journalArticle

  23. HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells

    Daneshpajooh, M., Karl Bacos, Bysani, M., Bagge, A., Ottosson Laakso, E., Petter Vikman, Lena Eliasson, Hindrik Mulder & Charlotte Ling, 2017 Jan, In : Diabetologia. 60, 1, p. 116–125

    Research output: Contribution to journalArticle

  24. Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes

    L Shcherbina, A Edlund, J L S Esguerra, Abels, M., Zhou, Y., Ottosson-Laakso, E., C B Wollheim, O Hansson, L Eliasson & N Wierup, 2017, In : Molecular and Cellular Endocrinology. 447, p. 52-60

    Research output: Contribution to journalArticle

  25. Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

    Motterle, A., Gattesco, S., Peyot, M. L., Jonathan Lou S. Esguerra, Ruiz-Gomez, A., Laybutt, D. R., Gilon, P., Burdet, F., Ibberson, M., Lena Eliasson, Prentki, M. & Regazzi, R., 2017, In : Molecular Metabolism. 6, 11, p. 1407-1418

    Research output: Contribution to journalArticle

  26. Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival

    Juan-Mateu, J. A., Rech, T. H., Villate, O., Lizarraga-Mollinedo, E., Anna Wendt, Turatsinze, J-V., Brondani, L. A., Nardelli, T. R., Nogueira, T. C., Jonathan Esguerra, Alvelos, M. I. E., Marchetti, P., Lena Eliasson & Eizirik, D. E. L., 2017, In : Journal of Biological Chemistry. 292, 8, p. 3466-3480

    Research output: Contribution to journalArticle

  27. Non-coding RNAs in beta cell insulin secretion - emerging players in Type 2 Diabetes pathogenesis

    Jones Ofori, 2017, Lund: Lund University, Faculty of Medicine. 76 p.

    Research output: ThesisDoctoral Thesis (compilation)

  28. PIWI-interacting RNAs as novel regulators of pancreatic beta cell function

    Henaoui, I. S., Jacovetti, C., Mollet, I., Guay, C., Sobel, J., Lena Eliasson & Regazzi, R., 2017, In : Diabetologia. 60, 10, p. 1977-1986

    Research output: Contribution to journalArticle

  29. 2016
  30. Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion

    Salunkhe, V. A., Mollet, I., Jones K. Ofori, Malm, H. A., Jonathan L S Esguerra, Reinbothe, T., Karin G. Stenkula, Anna Wendt, Lena Eliasson & Vikman, J., 2016 Aug, In : EBioMedicine. 10, p. 185-194

    Research output: Contribution to journalArticle

  31. Diabetes: Partners for life

    Lena Eliasson & Anna Wendt, 2016 May 18, In : eLife. 5, p. 1-2 e16798.

    Research output: Contribution to journalArticle

  32. Rosuvastatin treatment affects both basal and glucose-induced insulin secretion in INS-1 832/13 cells

    Salunkhe, V. A., Olof Elvstam, Lena Eliasson & Anna Wendt, 2016 Mar 1, In : PLoS ONE. 11, 3, e0151592.

    Research output: Contribution to journalArticle

  33. Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

    Karl Bacos, Gillberg, L., Petr Volkov, Olsson, A. H., Hansen, T., Pedersen, O., Gjesing, A. P., Eiberg, H., Tuomi, T., Almgren, P., Leif Groop, Lena Eliasson, Allan Vaag, Dayeh, T. & Charlotte Ling, 2016, In : Nature Communications. 7, 11089.

    Research output: Contribution to journalArticle

  34. CFTR in pancreatic islets

    Anna Edlund, 2016, 150 ed. Lund: Lund University, Faculty of Medicine. 69 p.

    Research output: ThesisDoctoral Thesis (compilation)

  35. Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans.

    Bennet, H., Mollet, I., Balhuizen, A., Medina Benavente, A., Nagorny, C., Bagge, A., Fadista, J., Ottosson Laakso, E., Petter Vikman, Dekker Nitert, M., Lena Eliasson, Nils Wierup, Isabella Artner & Malin Fex, 2016, In : Diabetologia. 59, 4, p. 744-754

    Research output: Contribution to journalArticle

  36. Transcriptional regulation of miRNA-212 and miRNA-132 and their fine-tuning function of beta cell insulin secretion

    Malm, H., 2016, Lund: Lund University, Faculty of Medicine. 75 p.

    Research output: ThesisDoctoral Thesis (compilation)

  37. 2015
  38. MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells

    Salunkhe, V. A., J. Ofori, Gandasi, N. R., Salö, S. A., A. Wendt, Barg, S., J.L.S. Esguerra & L. Eliasson, 2015 Sep 1, In : Diabetologia. 58, Suppl. 1, p. S128 1 p.

    Research output: Contribution to journalPublished meeting abstract

  39. Type 2 diabetes mellitus

    DeFronzo, R. A., Ferrannini, E., Leif Groop, Henry, R. R., Herman, W. H., Holst, J. J., Hu, F. B., Kahn, C. R., Raz, I., Shulman, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015 Jul 23, In : Nature Reviews Disease Primers. 1, 15019.

    Research output: Contribution to journalArticle

  40. Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents

    Christensen, G. L., Jacobsen, M. L. B., Anna Wendt, Mollet, I., Friberg, J., Frederiksen, K. S., Meyer, M., Bruun, C., Lena Eliasson & Billestrup, N., 2015, In : Diabetologia. 58, 6, p. 1282-1290

    Research output: Contribution to journalArticle

  41. DNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular Events.

    Zaina, S., Isabel Goncalves, Carmona, F. J., Gomez, A., Heyn, H., Mollet, I., Moran, S., Varol, N. & Esteller, M., 2015, In : Arteriosclerosis, Thrombosis and Vascular Biology. 35, 8, p. 1835-1842

    Research output: Contribution to journalArticle

  42. Effects of Ca2+, microRNAs, and rosuvastatin on insulin-secreting beta cell function

    Salunkhe, V. A., 2015, Islet cell exocytosis, Dept of Clinical Scinces. 79 p.

    Research output: ThesisDoctoral Thesis (compilation)

  43. Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice

    Bodin, J., Kocbach Bølling, A., Anna Wendt, Lena Eliasson, Becher, R., Kuper, F., Løvik, M. & Nygaard, U. C., 2015, In : Aquatic Toxicology. 2, p. 99-110 12 p.

    Research output: Contribution to journalArticle

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