Organisational unit: Research group
Research areas and keywords
UKÄ subject classification
- Endocrinology and Diabetes
- Cardiac and Cardiovascular Systems
- Medical Genetics
- Cell and Molecular Biology
- Kidney, nephropathy
Diabetes mellitus is a lifelong, incapacitating disease affecting multiple organs. Worldwide prevalence figures estimate that there will be 380 million diabetic patients in 2025. Presently, diabetes can neither be prevented nor cured and the disease is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular disease) as well as microvascular disorders leading to damage of the small blood vessels of the kidney (nephropathy), eye (retinopathy) and peripheral nerves (neuropathy). These complications impose an immense burden on the quality of life of the patients and account for more than 10% of health care costs in Europe. Therefore, novel means to prevent these devastating diabetic complications are needed.
Recent research outputs
Cascading proton transfers are a hallmark of the catalytic mechanism of SAM-dependent methyltransferasesNa Zhao, L. & Philipp Kaldis, 2020 Apr 30, In : FEBS Letters.
Research output: Contribution to journal › Article
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