Organisational unit: Research group
Research areas and keywords
UKÄ subject classification
- Cancer and Oncology
- Immunology in the medical area
- Bioinformatics (Computational Biology)
- Medical Genetics
- Cell and Molecular Biology
- Clinical Laboratory Medicine
- Multiple myeloma, leukemia, ALL, AML, CRISPR/Cas9, shRNA, Flow cytometry, blood cell formation, population genetics, hematology, genomics, computional biology, bioinformatics
Our research group combines mathematics and genomics to address clinically important problems in hematology and immunology. Current projects focus on blood cell formation and blood disorders, e.g. multiple myeloma and childhood leukemia. The team of computer scientists, clinicians, and molecular biologists work closely together. Computational models are combined with genetic approaches to identify risk genes for blood- and immunological disorders, as well as regulators of the cell functions. Our network of international collaborations include deCODE Genetics and the Broad Institute. Our research has contributed to the understanding of inherited susceptibility to multiple myeloma, the identification of the gene behind the Vel-blood group and a diagnostic tool for the blood group used in clinical practice. Sources of funding include e.g. the Swedish foundation for Strategic Research, the Knut and Alice Wallenberg Foundation, The Swedish Childhood Cancer Foundation and Swedish Research Council.
Recent research outputs
Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in SwedenAli, M., Konstantinos Lemonakis, Anna-Karin Wihlborg, Veskovski, L., Ingemar Turesson, Mellqvist, U-H., Urban Gullberg, Markus Hansson & Björn Nilsson, 2019 Jul 30, In : Blood Cancer Journal. 9, 8, 57.
Research output: Contribution to journal › Letter
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