Immunology

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cell and Molecular Biology
  • Immunology in the medical area
  • Cancer and Oncology

Research

Inflammation can be induced both by tissue damage and infection and the purpose of this physiological response is to repair damaged tissue and return it to normalcy. Inflammation is also a central component of both autoimmune disease and cancer. During such conditions, however, the inflammatory response is not properly regulated and the response becomes chronic and a component of disease. The “sterile” inflammation induced upon tissue injury has been shown to be due to be partially caused by the release of components from damaged and dying cells. These so-called DAMP (damage associated molecular patterns) molecules have been shown to be ligands of pro-inflammatory receptors such as TLRs and RAGE.

Recent research outputs

Ulrika Norin, Carola Rintisch, Liesu Meng, Florian Forster, Diana Ekman, Jonatan Tuncel, Katrin Klocke, Johan Bäcklund, Min Yang, Michael Y. Bonner, Gonzalo Fernandez Lahore, Jaime James, Klementy Shchetynsky, Maria Bergquist, Inger Gjertsson, Norbert Hubner, Liselotte Bäckdahl & Rikard Holmdahl, 2021, In: Nature Communications. 12, 1, 610.

Research output: Contribution to journalArticle

Thomas M. Fenton, Peter B. Jørgensen, Kristoffer Niss, Samuel J.S. Rubin, Urs M. Mörbe, Lene B. Riis, Clément Da Silva, Adam Plumb, Julien Vandamme, Henrik L. Jakobsen, Søren Brunak, Aida Habtezion, Ole H. Nielsen, Bengt Johansson-Lindbom & William W. Agace, 2020 Mar 17, In: Immunity. 52, 3, p. 557-570 21 p.

Research output: Contribution to journalArticle

Jonatan Tuncel, Jens Holmberg, Sabrina Haag, Malin Hultqvist Hopkins, Lena Wester-Rosenlöf, Stefan Carlsen, Peter Olofsson & Rikard Holmdahl, 2020, In: Arthritis Research and Therapy. 22, 1, 95.

Research output: Contribution to journalArticle

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