Lung Bioengineering and Regeneration

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  1. 2019
  2. The oncogene ECT2 contributes to a hyperplastic, proliferative lung epithelial cell phenotype in IPF

    Ulke, H. M., Mutze, K., Lehmann, M., Darcy E Wagner, Heinzelmann, K., Günther, A., Eickelberg, O. & Königshoff, M., 2019 May 30, In : American Journal of Respiratory Cell and Molecular Biology.

    Research output: Contribution to journalArticle

  3. Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

    Boza-Serrano, A., Ruiz, R., Sanchez-Varo, R., García-Revilla, J., Yang, Y., Jimenez-Ferrer, I., Paulus, A., Wennström, M., Vilalta, A., Allendorf, D., Davila, J. C., Stegmayr, J., Jiménez, S., Roca-Ceballos, M. A., Navarro-Garrido, V., Swanberg, M., Hsieh, C. L., Real, L. M., Englund, E., Linse, S. & 7 othersHakon Leffler, Ulf J. Nilsson, Brown, G. C., Gutierrez, A., Vitorica, J., Venero, J. L. & Tomas Deierborg, 2019 Apr 20, In : Acta Neuropathologica.

    Research output: Contribution to journalArticle

  4. Extracellular and intracellular small-molecule galectin-3 inhibitors

    John Stegmayr, Zetterberg, F., Carlsson, M. C., Huang, X., Sharma, G., Kahl-Knutson, B., Schambye, H., Ulf J. Nilsson, Stina Oredsson & Hakon Leffler, 2019 Feb 18, In : Scientific Reports. 9, 1, 2186.

    Research output: Contribution to journalArticle

  5. Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling

    Gerckens, M., Hani N Alsafadi, Darcy E Wagner, Lindner, M., Burgstaller, G. & Königshoff, M., 2019 Feb 12, In : Journal of visualized experiments : JoVE. 144, e58437 .

    Research output: Contribution to journalArticle

  6. Evolution of Bioengineered Lung Models: Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology

    Doryab, A., Sinem Tas, Taskin, M. B., Yang, L., Hilgendorff, A., Groll, J., Darcy E. Wagner & Schmid, O., 2019 Jan 1, In : Advanced Functional Materials. 20 p., 1903114.

    Research output: Contribution to journalReview article

  7. 3D printing of decellularised porcine lung ECM

    Sinem Tas, Deniz A. Bölükbas, Hani Alsafadi & Darcy E. Wagner, 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Swiss Society for Biomaterials, Vol. 40. p. 962-962 1 p.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  8. Chain End-Functionalized Polymer Brushes with Switchable Fluorescence Response

    Sinem Tas, Kopec´, M., van der Pol, R., Cirelli, M., de Vries, I., Deniz A. Bölükbas, Tempelman, K., Benes, N. E., Hempenius, M. A., Vancso, G. J. & de Beer, S., 2019, In : Macromolecular Chemistry and Physics. 220, 5, 1800537.

    Research output: Contribution to journalArticle

  9. Clickable, hybrid hydrogels as tissue culture platforms for modeling chronic pulmonary diseases in vitro

    Petrou, C. L., Darling, N. J., Deniz A. Bölükbas, Darcy E. Wagner & Magin, C. M., 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Swiss Society for Biomaterials, Vol. 40.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  10. Fine-tuning lung cancer nanotherapy using closed cardiopulmonary circulation

    D. A. Bölükbas, Morrone, C., Doryab, A., Datz, S., Gößl, D., Meyer-Schwickerath, C., Vreka, M., van Rijt, S. H., Stöger, T., Stathopoulos, G. T., S. Lindstedt, Bein, T., Meiners, S. & D. E. Wagner, 2019, Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium: 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence. Swiss Society for Biomaterials, Vol. 40.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  11. Translating Basic Research into Safe and Effective Cell-based Treatments for Respiratory Diseases

    Ikonomou, L., Darcy E Wagner, Turner, L. & Weiss, D. J., 2019, In : Annals of the American Thoracic Society. 16, 6, p. 657-668

    Research output: Contribution to journalArticle

  12. 2018
  13. Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

    Ota, C., Ng-Blichfeldt, J-P., Korfei, M., Hani N. Alsafadi, Lehmann, M., Skronska-Wasek, W., Martina M. De Santis, Guenther, A., Darcy Wagner & Königshoff, M., 2018 Aug 28, In : Scientific Reports. 8, 12983.

    Research output: Contribution to journalArticle

  14. Co-opting of ClinicalTrials.gov by patient-funded studies

    Darcy E. Wagner, Turner, L., Panoskaltsis-Mortari, A., Weiss, D. J. & Ikonomou, L., 2018 Aug, In : The Lancet Respiratory Medicine. 6, 8, p. 579-581

    Research output: Contribution to journalArticle

  15. Acellular human lung scaffolds to model lung disease and tissue regeneration

    Gilpin, S. E. & Darcy E. Wagner, 2018 Jun 30, In : European Respiratory Review. 27, 148, 180021.

    Research output: Contribution to journalArticle

  16. TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner

    van der Velden, J. L., Darcy E. Wagner, Lahue, K. G., Abdalla, S. T., Lam, Y. W., Weiss, D. J. & Janssen-Heininger, Y. M. W., 2018 Jun 1, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 6, p. L984-L997

    Research output: Contribution to journalArticle

  17. Early Career Members at the ERS Lung Science Conference: cell-matrix interactions in lung disease and regeneration: Early career forum

    Almendros, I., Hani N. Alsafadi, Deniz Bölükbas, Collins, J. JP., Duch, P., Garrido-Martin, E. M., Kahn, N., Karampitsakos, T., Irma Mahmutovic Persson, Tzouvelekis, A., Franziska Uhl & Bartel, S., 2018 Jun, In : Breathe. 14, 2, p. e78-e83

    Research output: Contribution to journalArticle

  18. Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring

    Jiang, D., Correa-Gallegos, D., Christ, S., Stefanska, A., Liu, J., Ramesh, P., Rajendran, V., Martina M. De Santis, Darcy E. Wagner & Rinkevich, Y., 2018 Apr 1, In : Nature Cell Biology. 20, 4, p. 422-431 10 p.

    Research output: Contribution to journalArticle

  19. Avian lungs: A novel scaffold for lung bioengineering

    Wrenn, S. M., Griswold, E. D., Franziska E Uhl, Uriarte, J. J., Park, H. E., Coffey, A. L., Dearborn, J. S., Ahlers, B. A., Deng, B., Lam, Y-W., Huston, D. R., Lee, P. C., Darcy E Wagner & Weiss, D. J., 2018, In : PLoS ONE. 13, 6, p. e0198956

    Research output: Contribution to journalArticle

  20. 2017
  21. LSC - 2017 - Hippo-YAP/TAZ signaling is deranged in IPF

    Darcy Wagner, Hani Alsafadi, Mutze, K., Costa, R., Stein, M., Schiller, H., Kaminski, N. & Koenigshoff, M., 2017 Sep 6, In : European Respiratory Journal. 50, Suppl. 61, OA475.

    Research output: Contribution to journalPublished meeting abstract

  22. Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem

    American Thoracic Society Respiratory Cell and Molecular Biology Assembly Stem Cell Working Group, 2017 Apr 1, In : American Journal of Respiratory and Critical Care Medicine. 195, 7, p. P13-P14

    Research output: Contribution to journalDebate/Note/Editorial