Medical Microspectroscopy

Organisational unit: Research group


Ageing of the world’s population has amplified neurodegenerative disorders, of which Alzheimer’s disease (AD) and Parkinson’s disease (PD) are most common dementias. Both disorders are characterized by abnormal aggregation of proteins in brain. The molecular mechanism (or mechanisms) leading to the abnormal accumulation of ggregation of proteins remains unknown. We want to understand why abnormal protein aggregation begins and how these aggregated proteins (a-synuclein, amyloid-ß, and tau) may interact in vitro and in vivo combining advanced microscopy with synchrotron based micro- and nano-spectrocopic techniques.

Recent research outputs

Oxana Klementieva, Sandt, C., Isak Martinsson, Kansiz, M., Gunnar Keppler Gouras & Borondics, F., 2020 Feb 7, In : Advanced Science. 9 p., 1903004.

Research output: Contribution to journalArticle

Benseny-Cases, N., Álvarez-Marimon, E., Aso, E., Carmona, M., Oxana Klementieva, Appelhans, D., Ferrer, I. & Cladera, J., 2020, In : Scientific Reports. 10, 1, 5888.

Research output: Contribution to journalArticle

Oxana Klementieva, 2019 Sep 9, Dendrimers, Dendrons and Dendritic Polymers. Ziemba, B., Franiak-Pietryga, I. & Shcharbin, D. (eds.). London, United Kingdom: InTech Open Access Publisher, Vol. Dendrimers, Dendrons and Dendritic Polymers. p. 1-16 16 p.

Research output: Chapter in Book/Report/Conference proceedingBook chapter

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