Medical Protein Science

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  1. 2019
  2. Novel ABCA1 peptide agonists with antidiabetic action

    Azhar, S., Bittner, S., Hu, J., Shen, W. J., Cortez, Y., Hao, X., Han, L., Jens O. Lagerstedt, Kraemer, F. B. & Johansson, J. O., 2019 Jan 15, In : Molecular and Cellular Endocrinology. 480, p. 1-11

    Research output: Contribution to journalArticle

  3. ApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice

    Edmunds, S. J., Liébana-García, R., Oktawia Nilsson, Domingo-Espín, J., Caitriona Grönberg, Karin G Stenkula & Jens O Lagerstedt, 2019, In : Diabetologia. 62, 7, p. 1257-1267

    Research output: Contribution to journalArticle

  4. 2018
  5. Antioxidants from plants protect against skin photoaging

    Petruk, G., Rita Del Giudice, Rigano, M. M. & Monti, D. M., 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 1454936.

    Research output: Contribution to journalReview article

  6. Baculovirus-driven protein expression in insect cells: A benchmarking study

    Stolt-Bergner, P., Benda, C., Bergbrede, T., Besir, H., Celie, P. H. N., Chang, C., Drechsel, D., Fischer, A., Geerlof, A., Giabbai, B., van den Heuvel, J., Huber, G., Knecht, W., Lehner, A., Lemaitre, R., Nordén, K., Pardee, G., Racke, I., Remans, K., Sander, A. & 7 othersScholz, J., Stadnik, M., Storici, P., Weinbruch, D., Zaror, I., Lua, L. H. L. & Suppmann, S., 2018, In : Journal of Structural Biology. 203, 2, p. 71-80

    Research output: Contribution to journalArticle

  7. High-efficient bacterial production of human ApoA-I amyloidogenic variants

    Rita Del Giudice & Jens O. Lagerstedt, 2018, In : Protein Science. 27, 12, p. 2101-2109 9 p.

    Research output: Contribution to journalArticle

  8. 2017
  9. Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels

    Rita Del Giudice, Domingo-Espín, J., Iacobucci, I., Oktawia Nilsson, Monti, M. C., Monti, D. M. & Jens O Lagerstedt, 2017, In : Biochimica et biophysica acta. 1863, 12, p. 3038-3048 11 p.

    Research output: Contribution to journalArticle

  10. Structures of apolipoprotein A-I in high density lipoprotein generated by electron microscopy and biased simulations

    Zhu, L., Jitka Petrlova, Gysbers, P., Hebert, H., Wallin, S., Jegerschöld, C. & Jens Lagerstedt, 2017, In : Biochimica et Biophysica Acta - General Subjects. 1861, 11, Part A, p. 2726-2738

    Research output: Contribution to journalArticle

  11. 2016
  12. Perilipin 1 binds to aquaporin 7 in human adipocytes and controls its mobility via protein kinase A mediated phosphorylation

    Söndergaard Hansen, J., Christian Krintel, Hernebring, M., Haataja, T. J. K., Sofia de Marè, Sebastian Wasserstrom, Kosinska-Eriksson, U., Palmgren, M., Cecilia Holm, Karin G. Stenkula, Jones, H. A. & Karin Lindkvist-Petersson, 2016 Dec 1, In : Metabolism, Clinical and Experimental. 65, 12, p. 1731-1742 12 p.

    Research output: Contribution to journalArticle

  13. Molecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function

    Jitka Petrlova, Hilt, S., Budamagunta, M., Domingo-Espín, J., Voss, J. C. & Jens O. Lagerstedt, 2016 Oct 1, In : Biopolymers. 105, 10, p. 683-692 10 p.

    Research output: Contribution to journalArticle

  14. 2015
  15. Structural and Functional Analysis of the ApolipoproteinA-I A164S Variant.

    Jonathan Dalla-Riva, Jens Lagerstedt & Jitka Petrlova, 2015, In : PLoS ONE. 10, 11, e0143915.

    Research output: Contribution to journalArticle

  16. 2014
  17. Conformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I

    Jitka Petrlova, Bhattacherjee, A., Boomsma, W., Wallin, S., Jens O Lagerstedt & Anders Irbäck, 2014 Nov, In : Protein Science. 23, 11, p. 1559-71 13 p.

    Research output: Contribution to journalArticle

  18. APOLIPOPROTEIN A-I DERIVED PEPTIDES FOR TREATMENT OF HYPERGLYCAEMIA

    Jens Lagerstedt & Karin Stenkula, 2014 Jan 27, IPC No. WO 2014/114787 A1, Patent No. 019-094-625-110-905 , 2014 Jan 27, Priority date 2013 Jan 25, Priority No. 1300064-1

    Research output: Patent

  19. Conformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I.

    Jitka Petrlova, Bhattacherjee, A., Boomsma, W., Wallin, S., Jens Lagerstedt & Irbäck, A., 2014, In : Protein Science. 23, 11, p. 1559-1571

    Research output: Contribution to journalArticle

  20. Galiellalactone is a Direct Inhibitor of STAT3 in Prostate Cancer Cells.

    Nicholas Don-Doncow, Escobar Gabriel, Z., Johansson, M. H., Sven Kjellström, Garcia, V., Munoz, E., Olov Sterner, Anders Bjartell & Rebecka Hellsten, 2014, In : Journal of Biological Chemistry. 289, 23, p. 15969-15978

    Research output: Contribution to journalArticle

  21. The fungal metabolite galiellalactone interferes with the nuclear import of NF-κB and inhibits HIV-1 replication.

    Pérez, M., Soler-Torronteras, R., Collado, J. A., Limones, C. G., Rebecka Hellsten, Johansson, M. H., Sterner, O., Anders Bjartell, Calzado, M. A. & Muñoz, E., 2014, In : Chemico-Biological Interactions. 214, Mar 11, p. 69-76

    Research output: Contribution to journalArticle

  22. 2013
  23. Double Electron-Electron Resonance Probes Ca2+-Induced Conformational Changes and Dimerization of Recoverin

    Myers, W. K., Xu, X., Li, C., Jens Lagerstedt, Budamagunta, M. S., Voss, J. C., Britt, R. D. & Ames, J. B., 2013, In : Biochemistry. 52, 34, p. 5800-5808

    Research output: Contribution to journalArticle

  24. EPR assessment of protein sites for incorporation of Gd(III) MRI contrast labels.

    Jens Lagerstedt, Jitka Petrlova, Hilt, S., Marek, A., Chung, Y., Sriram, R., Budamagunta, M. S., Desreux, J. F., Thonon, D., Jue, T., Smirnov, A. I. & Voss, J., 2013, In : Contrast Media & Molecular Imaging. 8, 3, p. 252-264

    Research output: Contribution to journalArticle

  25. Impaired Tethering and Fusion of GLUT4 Vesicles in Insulin-Resistant Human Adipose Cells

    Lizunov, V. A., Lee, J-P., Skarulis, M. C., Zimmerberg, J., Cushman, S. W. & Karin Stenkula, 2013, In : Diabetes. 62, 9, p. 3114-3119

    Research output: Contribution to journalArticle

  26. The secondary structure of apolipoprotein A-I on 9.6-nm reconstituted high-density lipoprotein determined by EPR spectroscopy

    Oda, M. N., Budamagunta, M. S., Borja, M. S., Jitka Petrlova, Voss, J. C. & Jens Lagerstedt, 2013, In : The FEBS Journal. 280, 14, p. 3416-3424

    Research output: Contribution to journalArticle

  27. 2012
  28. Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

    Lizunov, V. A., Karin Stenkula, Lisinski, I., Gavrilova, O., Yver, D. R., Chadt, A., Al-Hasani, H., Zimmerberg, J. & Cushman, S. W., 2012, In : American Journal of Physiology: Endocrinology and Metabolism. 302, 8, p. E950-E960

    Research output: Contribution to journalArticle

  29. Postprandial apoE Isoform and Conformational Changes Associated with VLDL Lipolysis Products Modulate Monocyte Inflammation

    den Hartigh, L. J., Altman, R., Hutchinson, R., Jitka Petrlova, Budamagunta, M. S., Tetali, S. D., Jens Lagerstedt, Voss, J. C. & Rutledge, J. C., 2012, In : PLoS ONE. 7, 11, e50513.

    Research output: Contribution to journalArticle

  30. Reversible Michael additions: Covalent inhibitors and prodrugs.

    Johansson, M. H., 2012, In : Mini-Reviews in Medical Chemistry. 12, 13, p. 1330-1344

    Research output: Contribution to journalArticle

  31. The "beta-clasp" model of apolipoprotein A-I - A lipid-free solution structure determined by electron paramagnetic resonance spectroscopy.

    Jens Lagerstedt, Budamagunta, M. S., Liu, G. S., Devalle, N. C., Voss, J. & Oda, M. N., 2012, In : Biochimica et biophysica acta. 1821, 3, p. 448-455

    Research output: Contribution to journalArticle

  32. The fibrillogenic L178H variant of apolipoprotein A-I forms helical fibrils.

    Jitka Petrlova, Duong, T., Cochran, M. C., Axelsson, A., Mörgelin, M., Roberts, L. M. & Jens Lagerstedt, 2012, In : Journal of Lipid Research. 53, 3, p. 390-398

    Research output: Contribution to journalArticle