Molecular Pediatric Oncology

Organisational unit: Research group

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  1. 2019
  2. Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma

    Sofie Mohlin, Karin Hansson, Radke, K., Martinez, S., Blanco-Apiricio, C., Garcia-Ruiz, C., Charlotte Welinder, Esfandyari, J., O'Neill, M., Pastor, J., Kristoffer von Stedingk & Daniel Bexell, 2019 Aug 1, In : EMBO Molecular Medicine. 11, 8, e10058.

    Research output: Contribution to journalArticle

  3. The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis

    Linda Holmquist Mengelbier, Lindell-Munther, S., Hiroaki Yasui, Jansson, C., Esfandyari, J., Jenny Karlsson, Lau, K., Hui, C. C., Daniel Bexell, Hopyan, S. & David Gisselsson, 2019 Jan, In : Journal of Pathology. 247, 1

    Research output: Contribution to journalArticle

  4. Multidimensional intratumour heterogeneity in neuroblastoma

    Kristoffer Von Stedingk, David Gisselsson & Daniel Bexell, 2019, In : Oncotarget. 10, 1, p. 3-5 3 p.

    Research output: Contribution to journalDebate/Note/Editorial

  5. 2018
  6. Patient-derived xenograft models reveal intratumor heterogeneity and temporal stability in neuroblastoma

    Braekeveldt, N., Von Stedingk, K., Fransson, S., Martinez-Monleon, A., Lindgren, D., Axelson, H., Levander, F., Willforss, J., Hansson, K., Øra, I., Backman, T., Börjesson, A., Beckman, S., Esfandyari, J., Berbegall, A. P., Noguera, R., Karlsson, J., Koster, J., Martinsson, T., Gisselsson, D. & 2 othersSven Påhlman & Daniel Bexell, 2018, In : Cancer Research. 78, 20, p. 5958-5969 12 p.

    Research output: Contribution to journalArticle

  7. Patient-derived xenografts as preclinical neuroblastoma models

    Noémie Braekeveldt & Daniel Bexell, 2018, In : Cell and Tissue Research. 372, 2, p. 233-243

    Research output: Contribution to journalArticle

  8. 2017
  9. Patient-derived xenografts as preclinical models of neuroblastoma

    Noémie Braekeveldt, 2017, Lund: Lund University, Faculty of Medicine.

    Research output: ThesisDoctoral Thesis (compilation)

  10. 2016
  11. Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer

    Wigerup, C., Sven Påhlman & Daniel Bexell, 2016 Aug, In : Pharmacology and Therapeutics. 164, p. 152-169

    Research output: Contribution to journalReview article

  12. Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours

    Noémie Braekeveldt, Wigerup, C., Tadeo, I., Beckman, S., Caroline Sandén, Jönsson, J., Jonas S Erjefält, Berbegall, A. P., Anna Börjesson, Backman, T., Ingrid Øra, Navarro, S., Noguera, R., David Gisselsson, Sven Påhlman & Daniel Bexell, 2016, In : Cancer Letters. 375, 2, p. 384-389

    Research output: Contribution to journalArticle

  13. 2015
  14. Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

    Holmquist Mengelbier, L., Karlsson, J., Lindgren, D., Valind, A., Lilljebjörn, H., Jansson, C., Bexell, D., Braekeveldt, N., Ameur, A., Jonson, T., Kultima, H. G., Isaksson, A., Asmundsson, J., Versteeg, R., Rissler, M., Fioretos, T., Sandstedt, B., Börjesson, A., Backman, T., Pal, N. & 3 othersIngrid Øra, Mayrhofer, M. & David Gisselsson Nord, 2015, In : Nature Communications. 6, 6125.

    Research output: Contribution to journalArticle

  15. Neuroblastoma Patient-Derived Orthotopic Xenografts Retain Metastatic Patterns and Geno- and Phenotypes of Patient Tumours.

    Noémie Braekeveldt, Wigerup, C., David Gisselsson Nord, Sofie Mohlin, Merselius, M., Beckman, S., Tord Jonson, Anna Börjesson, Backman, T., Tadeo, I., Berbegall, A. P., Ingrid Øra, Navarro, S., Noguera, R., Sven Påhlman & Daniel Bexell, 2015, In : International Journal of Cancer. 136, 5, p. E252-E261

    Research output: Contribution to journalArticle

  16. PI3K-mTORC2 but not PI3K-mTORC1 Regulates Transcription of HIF2A/EPAS1 and Vascularization in Neuroblastoma.

    Sofie Mohlin, Hamidian, A., Kristoffer von Stedingk, Bridges, E., Wigerup, C., Daniel Bexell & Sven Påhlman, 2015, In : Cancer Research. 75, 21, p. 4617-4628

    Research output: Contribution to journalArticle