Molecular therapeutics in breast cancer

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  1. 2020
  2. Whole-genome sequencing of triple negative breast cancers in a standard population-based clinical setting

    Johan Staaf, Dominik Glodzik, Ana Bosch Campos, Johan Vallon-Christersson, Christel Reuterswärd, Jari Häkkinen, Andrea Degasperi, Tauanne Dias Amarante, Lao Saal, Cecilia Hegardt, Hilary Stobart, Anna Ehinger, Christer Larsson, Lisa Ryden, Niklas Loman, Martin Malmberg, Anders Kvist, Hans Ehrencrona, Helen R. Davies, Åke Borg & 1 others, Serena Nik-Zainal, 2020 Feb 6, In : Breast Cancer Research and Treatment. 180, p. 531-532

    Research output: Contribution to journalPublished meeting abstract

  3. 2019
  4. Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study

    Johan Staaf, Dominik Glodzik, Ana Bosch, Johan Vallon-Christersson, Christel Reuterswärd, Jari Häkkinen, Andrea Degasperi, Tauanne Dias Amarante, Lao H Saal, Cecilia Hegardt, Hilary Stobart, Anna Ehinger, Christer Larsson, Lisa Rydén, Niklas Loman, Martin Malmberg, Anders Kvist, Hans Ehrencrona, Helen R Davies, Åke Borg & 1 others, Serena Nik-Zainal, 2019, In : Nature Medicine. 25, p. 1526–1533

    Research output: Contribution to journalArticle

  5. 2017
  6. Strategies to design clinical studies to identify predictive biomarkers in cancer research

    Jose Luis Perez-Gracia, Miguel F. Sanmamed, Ana Bosch Campos, Ana Patiño-Garcia, Kurt A. Schalper, Victor Segura, Joaquim Bellmunt, Josep Tabernero, Christopher J. Sweeney, Toni K. Choueiri, Miguel Martín, Juan Pablo Fusco, Maria Esperanza Rodriguez-Ruiz, Alfonso Calvo, Celia Prior, Luis Paz-Ares, Ruben Pio, Enrique Gonzalez-Billalabeitia, Alvaro Gonzalez Hernandez, David Páez & 15 others, Jose María Piulats, Alfonso Gurpide, Mapi Andueza, Guillermo Velasco, Roberto Pazo, Enrique Grande, Pilar Nicolas, Francisco Abad-Santos, Jesus Garcia-Donas, Daniel Castellano, María J. Pajares, Cristina Suarez, Ramon Colomer, Luis M. Montuenga & Ignacio Melero, 2017 Feb 1, In : Cancer Treatment Reviews. 53, p. 79-97

    Research output: Contribution to journalReview article

  7. 2015
  8. PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer

    Ana Bosch Campos, Zhiqiang Li, Anna Bergamaschi, Haley Ellis, Eneda Toska, Aleix Prat, Jessica J. Tao, Daniel E. Spratt, Nerissa T. Viola-Villegas, Pau Castel, Gerard Minuesa, Natasha Morse, Jordi Rodón, Yasir Ibrahim, Javier Cortes, Jose Perez-Garcia, Patricia Galvan, Judit Grueso, Marta Guzman, John A. Katzenellenbogen & 8 others, Michaelz Kharas, Jason S. Lewis, Maura Dickler, Violeta Serra, Neal Rosen, Sarat Chandarlapaty, Maurizio Scaltriti & José Baselga, 2015 Apr 15, In : Science Translational Medicine. 7, 283, p. 1-11 283ra51.

    Research output: Contribution to journalArticle

  9. Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule

    Gabriella Honeth, Tommaso Schiavinotto, Federico Vaggi, Rebecca Marlow, Tokuwa Kanno, Ireneusz Shinomiya, Sara Lombardi, Bharath Buchupalli, Rosalind Graham, Patrycja Gazinska, Vernie Ramalingam, Joy Burchell, Anand D Purushotham, Sarah E Pinder, Attila Csikasz-Nagy & Gabriela Dontu, 2015 Apr 14, In : Stem Cell Reports. 4, 4, p. 699-711 13 p.

    Research output: Contribution to journalArticle

  10. 2014
  11. Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells

    Sara Lombardi, Gabriella Honeth, Christophe Ginestier, Ireneusz Shinomiya, Rebecca Marlow, Bharath Buchupalli, Patrycja Gazinska, John Brown, Steven Catchpole, Suling Liu, Ariel Barkan, Max Wicha, Anand Purushotham, Joy Burchell, Sarah Pinder & Gabriela Dontu, 2014 Jun 3, In : Stem Cell Reports. 2, 6, p. 780-93 14 p.

    Research output: Contribution to journalArticle

  12. Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium

    Gabriella Honeth, Sara Lombardi, Christophe Ginestier, Minhee Hur, Rebecca Marlow, Bharath Buchupalli, Ireneusz Shinomiya, Patrycja Gazinska, Silvia Bombelli, Vernie Ramalingam, Anand D Purushotham, Sarah E Pinder & Gabriela Dontu, 2014 May 27, In : Breast Cancer Research. 16, 3, R52.

    Research output: Contribution to journalArticle

  13. Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer

    Jessica J. Tao, Pau Castel, Nina Radosevic-Robin, Moshe Elkabets, Neil Auricchio, Nicola Aceto, Gregory Weitsman, Paul Barber, Borivoj Vojnovic, Haley Ellis, Natasha Morse, Nerissa Therese Viola-Villegas, Ana Bosch Campos, Dejan Juric, Saswati Hazra, Sharat Singh, Phillip Kim, Anna Bergamaschi, Shyamala Maheswaran, Tony Ng & 6 others, Frédérique Penault-Llorca, Jason S. Lewis, Lisa A. Carey, Charles M. Perou, José Baselga & Maurizio Scaltriti, 2014 Mar 25, In : Science Signaling. 7, 318, p. 1-9 ra29.

    Research output: Contribution to journalArticle

  14. 2013
  15. A novel model of dormancy for bone metastatic breast cancer cells

    Rebecca Marlow, Gabriella Honeth, Sara Lombardi, Massimiliano Cariati, Sonya Hessey, Aikaterini Pipili, Veronica Mariotti, Bharath Buchupalli, Katie Foster, Dominique Bonnet, Agamemnon Grigoriadis, Pranela Rameshwar, Anand Purushotham, Andrew Tutt & Gabriela Dontu, 2013 Dec 1, In : Cancer Research. 73, 23, p. 6886-99 14 p.

    Research output: Contribution to journalArticle

  16. mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer

    Moshe Elkabets, Sadhna Vora, Dejan Juric, Natasha Morse, Mari Mino-Kenudson, Taru Muranen, Jessica Tao, Ana Bosch Campos, Jordi Rodon, Yasir H Ibrahim, Violeta Serra, Vanessa Rodrik-Outmezguine, Saswati Hazra, Sharat Singh, Phillip Kim, Cornelia Quadt, Manway Liu, Alan Huang, Neal Rosen, Jeffrey A Engelman & 2 others, Maurizio Scaltriti & José Baselga, 2013 Jul 31, In : Science Translational Medicine. 5, 196, p. 1-14 196ra99.

    Research output: Contribution to journalArticle