Neurobiology

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  1. 2020
  2. Extensive clonal branching shapes the evolutionary history of high-risk pediatric cancers

    Andersson, N., Bakker, B., Karlsson, J., Anders Valind, Linda Holmquist Mengelbier, Spierings, D. C. J., Foijer, F. & David Gisselsson, 2020 Apr, In : Cancer Research. 80, 7, p. 1512-1523 12 p.

    Research output: Contribution to journalArticle

  3. 2019
  4. Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia

    Meeter, L. H. H., Steketee, R. M. E., Salkovic, D., Vos, M. E., Grossman, M., McMillan, C. T., Irwin, D. J., Boxer, A. L., Rojas, J. C., Olney, N. T., Karydas, A., Miller, B. L., Pijnenburg, Y. A. L., Barkhof, F., Sánchez-Valle, R., Lladó, A., Borrego-Ecija, S., Diehl-Schmid, J., Grimmer, T., Goldhardt, O. & 27 others, Alexander F. Santillo, Oskar Hansson, Susanne Vestberg, Borroni, B., Padovani, A., Galimberti, D., Scarpini, E., Rohrer, J. D., Woollacott, I. O. C., Synofzik, M., Wilke, C., De Mendonca, A., Vandenberghe, R., Benussi, L., Ghidoni, R., Binetti, G., Niessen, W. J., Papma, J. M., Seelaar, H., Jiskoot, L. C., De Jong, F. J., Donker Kaat, L., Del Campo, M., Teunissen, C. E., Bron, E. E., Van Den Berg, E. & Van Swieten, J. C., 2019, In : Journal of Neurology, Neurosurgery and Psychiatry. 90, 9, p. 997-1004 8 p.

    Research output: Contribution to journalArticle

  5. 2018
  6. Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain

    Luis Quintino, Namislo, A., Marcus Davidsson, Breger, L. S., Kavanagh, P., Martino Avallone, Elgstrand-Wettergren, E., Isaksson, C. & Cecilia Lundberg, 2018, In : Molecular Therapy - Methods and Clinical Development. 11, p. 29-39 11 p.

    Research output: Contribution to journalArticle

  7. 2017
  8. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats

    Tronci, E., Napolitano, F., Muñoz, A., Fidalgo, C., Rossi, F., Anders Björklund, Usiello, A. & Carta, M., 2017 Nov 1, In : Experimental Neurology. 297, p. 73-81 9 p.

    Research output: Contribution to journalArticle

  9. Preclinical effects of APOE ϵ4 on cerebrospinal fluid Aβ42 concentrations

    Lautner, R., Philip S. Insel, Skillbäck, T., Olsson, B., Landén, M., Frisoni, G. B., Herukka, S-K., Hampel, H., Wallin, A., Lennart Minthon, Oskar Hansson, Blennow, K., Niklas Mattsson & Zetterberg, H., 2017 Oct 23, In : Alzheimer's Research and Therapy. 9, 1, 87.

    Research output: Contribution to journalArticle

  10. Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain

    Thakur, P., Breger, L. S., Lundblad, M., Wan, O. W., Mattsson, B., Luk, K. C., Lee, V. M. Y., Trojanowski, J. Q. & Anders Björklund, 2017 Sep 26, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 39, p. E8284-E8293

    Research output: Contribution to journalArticle

  11. Preface

    Dunnett, S. & A. Björklund, 2017 Jan 1, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Vol. 230. p. xxv-xxvii (Progress in Brain Research).

    Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

  12. Mechanisms and use of neural transplants for brain repair

    Dunnett, S. B. & A. Björklund, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Dunnett, S. B. & Björklund, A. (eds.). Elsevier, Vol. 230. p. 1-51 (Progress in Brain Research; vol. 230).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  13. Preface

    Dunnett, S. B. & A. Björklund, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part B. Vol. 231. p. xxv-xxvii (Progress in Brain Research; vol. 231).

    Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

  14. Replacing Dopamine Neurons in Parkinson's Disease: How did it happen?

    Anders Björklund & Olle Lindvall, 2017, In : Journal of Parkinson's Disease. 7, s1, p. S23-S33

    Research output: Contribution to journalReview article

  15. 2016
  16. Brain activity and Alzheimer's disease: A complex relationship

    Oskar Hansson & Gunnar Gouras, 2016 Aug 1, In : Brain. 139, 8, p. 2109-2110 2 p.

    Research output: Contribution to journalDebate/Note/Editorial

  17. DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

    Patrick Aldrin-Kirk, Andreas Heuer, Wang, G., Mattsson, B., Lundblad, M., Malin Parmar & Tomas Björklund, 2016 Jun 1, In : Neuron. 90, 5, p. 955-968 14 p.

    Research output: Contribution to journalArticle

  18. α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

    Wan, O. W., Shin, E., Mattsson, B., Caudal, D., Svenningsson, P. & Anders Björklund, 2016 May 23, In : Scientific Reports. 6, 26285.

    Research output: Contribution to journalArticle

  19. Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.

    Alvarsson, A., Caudal, D., Anders Björklund & Svenningsson, P., 2016, In : Behavioural Brain Research. 296, p. 129-133

    Research output: Contribution to journalArticle

  20. 2015
  21. Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.

    Tozzi, A., de Iure, A., Bagetta, V., Tantucci, M., Durante, V., Quiroga-Varela, A., Costa, C., Di Filippo, M., Ghiglieri, V., Latagliata, E. C., Wegrzynowicz, M., Decressac, M., Giampà, C., Dalley, J. W., Xia, J., Gardoni, F., Mellone, M., El-Agnaf, O. M., Ardah, M. T., Puglisi-Allegra, S. & 4 others, Anders Björklund, Spillantini, M. G., Picconi, B. & Calabresi, P., 2015, In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  22. Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.

    Caudal, D., Alvarsson, A., Anders Björklund & Svenningsson, P., 2015, In : Experimental Neurology. 273, p. 243-252

    Research output: Contribution to journalArticle

  23. Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.

    Svenningsson, P., Carl Rosenblad, Af Edholm Arvidsson, K., Wictorin, K., Keywood, C., Shankar, B., Lowe, D. A., Anders Björklund & Håkan Widner, 2015, In : Brain. 138, Feb 10, p. 963-973

    Research output: Contribution to journalArticle

  24. GDNF is not required for catecholaminergic neuron survival in vivo.

    Kopra, J., Vilenius, C., Grealish, S., Härma, M-A., Varendi, K., Lindholm, J., Castrén, E., Võikar, V., Anders Björklund, Piepponen, T. P., Saarma, M. & Andressoo, J-O., 2015, In : Nature Neuroscience. 18, 3, p. 319-322

    Research output: Contribution to journalLetter

  25. Identification of the miRNA targetome in hippocampal neurons using RIP-seq.

    Malmevik, J., Petri, R., Klüssendorf, T., Knauff, P., Malin Åkerblom, Jenny G Johansson, Shamit Soneji & Johan Jakobsson, 2015, In : Scientific Reports. 5, 12609.

    Research output: Contribution to journalArticle

  26. Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.

    Volakakis, N., Tiklova, K., Decressac, M., Papathanou, M., Mattsson, B., Gillberg, L., Nobre, A., Anders Björklund & Perlmann, T., 2015, In : Journal of Neuroscience. 35, 42, p. 14370-14385

    Research output: Contribution to journalArticle

  27. Parkinson's Disease Case Ascertainment in the EPIC Cohort: The NeuroEPIC4PD Study

    Gallo, V., Brayne, C., Forsgren, L., Barker, R. A., Petersson, J., Hansson, O., Lindqvist, D., Ruffmann, C., Ishihara, L., Luben, R., Arriola, L., Bergareche, A., Gavrila, D., Erro, M. E., Vanacore, N., Sacerdote, C., Bueno-De-Mesquita, B., Vermeulen, R., Seelen, M., Sieri, S. & 15 others, Masala, G., Ramat, S., Kyrozis, A., Thricopolou, A., Panico, S., Mattiello, A., Kaaks, R., Teucher, B., Katzke, V., Kloss, M., Curry, L., Calboli, F., Riboli, E., Vineis, P. & Middleton, L., 2015, In : Neurodegenerative Diseases. 15, 6, p. 331-338

    Research output: Contribution to journalArticle

  28. Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.

    Thompson, L. & Anders Björklund, 2015, In : Neurobiology of Disease. 79, Apr 22, p. 28-40

    Research output: Contribution to journalReview article

  29. The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.

    Ruben Smith, Wu, K., Hart, T., Loane, C., Brooks, D. J., Anders Björklund, Per Odin, Piccini, P. & Politis, M., 2015, In : Neurobiology of Aging. 36, 4, p. 1736-1742

    Research output: Contribution to journalArticle

  30. Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.

    Bye, C. R., Marie Jönsson, Anders Björklund, Parish, C. L. & Thompson, L., 2015, In : Proceedings of the National Academy of Sciences. 112, 15, p. E1946-E1955

    Research output: Contribution to journalArticle

  31. Transposable Elements in Neural Progenitor Cells

    Fasching, L., 2015, Molecular Neurogenetics, Faculty of Medicine, Lund University. 74 p.

    Research output: ThesisDoctoral Thesis (compilation)

  32. 2014
  33. Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports

    Kefalopoulou, Z., Politis, M., Piccini, P., Mencacci, N., Bhatia, K., Jahanshahi, M., Håkan Widner, Rehncrona, S., Brundin, P., Anders Björklund, Olle Lindvall, Limousin, P., Quinn, N. & Foltynie, T., 2014 Jan, In : JAMA Neurology. 71, 1, p. 83-7 5 p.

    Research output: Contribution to journalArticle

  34. Dynamic changes in dopamine neuron function after DNSP-11 treatment: Effects in vivo and increased ERK 1/2 phosphorylation in vitro.

    Fuqua, J. L., Littrell, O. M., Lundblad, M., Turchan-Cholewo, J., Abdelmoti, L. G., Galperin, E., Bradley, L. H., Cass, W. A., Gash, D. M. & Gerhardt, G. A., 2014, In : Peptides. 54, Jan 7, p. 1-8

    Research output: Contribution to journalArticle

  35. Generation of induced neurons via direct conversion in vivo and in vitro

    Torper, O., 2014, Neurobiology. 125 p.

    Research output: ThesisDoctoral Thesis (compilation)

  36. Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.

    Grealish, S., Diguet, E., Agnete Kirkeby, Mattsson, B., Andreas Heuer, Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Anders Björklund & Malin Parmar, 2014, In : Cell Stem Cell. 15, 5, p. 653-665

    Research output: Contribution to journalArticle

  37. microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons.

    Malin Åkerblom, Petri, R., Sachdeva, R., Klüssendorf, T., Mattsson, B., Gentner, B. & Johan Jakobsson, 2014, In : Development: For advances in developmental biology and stem cells. 141, 7, p. 1580-1588

    Research output: Contribution to journalArticle

  38. Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.

    Shin, E., Rogers, J. R., Devoto, P., Anders Björklund & Carta, M., 2014, In : Experimental Neurology. 257, Apr 18, p. 25-38

    Research output: Contribution to journalArticle

  39. The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.

    Shin, E., Lisci, C., Tronci, E., Fidalgo, C., Stancampiano, R., Anders Björklund & Carta, M., 2014, In : Neurobiology of Disease. 62, p. 233-240

    Research output: Contribution to journalArticle

  40. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons

    Iovino, M., Pfisterer, U., Holton, J. L., Lashley, T., Swingler, R. J., Calo, L., Treacy, R., Revesz, T., Malin Parmar, Goedert, M., Muqit, M. M. K. & Spillantini, M. G., 2014, In : Acta Neuropathologica. 127, 2, p. 283-295

    Research output: Contribution to journalArticle

  41. 2013
  42. A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.

    Christian Hansen, Tomas Björklund, Petit, G., Lundblad, M., Murmu, R., Brundin, P. & Jia-Yi Li, 2013, In : Neurobiology of Disease. 56C, April,30, p. 145-155

    Research output: Contribution to journalArticle

  43. Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

    Bezard, E., Munoz, A., Tronci, E., Pioli, E. Y., Li, Q., Porras, G., Anders Björklund & Carta, M., 2013, In : Neuroscience Research. 77, 4, p. 242-246

    Research output: Contribution to journalArticle

  44. Cell therapy for Parkinson's disease: what next?

    Anders Björklund & Kordower, J. H., 2013, In : Movement Disorders. 28, 1, p. 110-115

    Research output: Contribution to journalArticle

  45. Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

    Barker, R., Barrett, J., Mason, S. L. & Anders Björklund, 2013, In : Lancet Neurology. 12, 1, p. 84-91

    Research output: Contribution to journalReview article

  46. Generation of induced neurons via direct conversion in vivo.

    Torper, O., Pfisterer, U., Wolf, D., Pereira, M. J. M., Lau, S., Johan Jakobsson, Anders Björklund, Grealish, S. & Malin Parmar, 2013, In : Proceedings of the National Academy of Sciences. 110, 17, p. 7038-7043

    Research output: Contribution to journalArticle

  47. mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats

    Decressac, M. & Anders Björklund, 2013, In : Journal of Parkinson's Disease. 3, 1, p. 13-17

    Research output: Contribution to journalArticle

  48. NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.

    Decressac, M., Volakakis, N., Anders Björklund & Perlmann, T., 2013, In : Nature Reviews Neurology. 9, 11, p. 629-636

    Research output: Contribution to journalReview article

  49. Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism.

    Daniella Rylander, Bagetta, V., Pendolino, V., Zianni, E., Grealish, S., Gardoni, F., Di Luca, M., Calabresi, P., Angela Cenci Nilsson & Picconi, B., 2013, In : Proceedings of the National Academy of Sciences. 110, 46, p. E4375-E4384

    Research output: Contribution to journalArticle

  50. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia

    Bezard, E., Tronci, E., Pioli, E. Y., Li, Q., Porras, G., Anders Björklund & Carta, M., 2013, In : Movement Disorders. 28, 8, p. 1088-1096

    Research output: Contribution to journalArticle

  51. TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.

    Decressac, M., Mattsson, B., Weikop, P., Lundblad, M., Johan Jakobsson & Anders Björklund, 2013, In : Proceedings of the National Academy of Sciences. 110, 19, p. E1817-E1826

    Research output: Contribution to journalArticle

  52. TFEB: Pathogenic role and therapeutic target in Parkinson disease.

    Decressac, M. & Anders Björklund, 2013, In : Autophagy. 9, 8, p. 1244-1246

    Research output: Contribution to journalArticle

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