Organisational unit: Research group
Research areas and keywords
UKÄ subject classification
- Platelets, immunology, TRALI
Professor Semple joined St. Michaels Hospital in 1990 and was a Professor of Pharmacology at the University of Toronto. In 2016, he moved to Lund where he is a Professor of Transfusion Medicine and Group Leader in Platelet Immunology. He is a member of several organizations and has delivered over 150 presentations at international meetings. He is currently the Scientific Secretary of the ISBT, a member of the Scientific Committee on Megakaryocytes and Platelets of ASH and on the Editorial Board of Blood and Transfusion journals. His primary research interests include the pathogenesis of immune thrombocytopenia (ITP) where he studies animal models of platelet immunity. He also discovered Toll-like Receptors on platelets and has an interest in platelet-immune interactions. A third focus of his is understanding the pathogenic mechanisms that lead to Transfusion Related Acute Lung Injury (TRALI). He has authored more than 175 publications in the area of platelet immunology and TRALI.
Recent research outputs
John W. Semple & Kapur, R., 2020 May 18, In : Transfusion. 60, 5, p. 886-888 3 p.
Research output: Contribution to journal › Letter
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Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP)Kapur, R., Aslam, R., Speck, E. R., Johan M. Rebetz & John W. Semple, 2019 May 30, In : Platelets.
Research output: Contribution to journal › Article