Protein Chemistry, Malmö

Organisational unit: Research group

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  1. 2020
  2. Outside in: Roles of complement in autophagy

    Ben C. King, Klaudia Kulak, Lucie Colineau & Anna M. Blom, 2020 Jul 4, In : British Journal of Pharmacology.

    Research output: Contribution to journalReview article

  3. A soft tick Ornithodoros moubata salivary protein OmCI is a potent inhibitor to prevent avian complement activation

    Frye, A. M., Hart, T. M., Tufts, D. M., Ram, S., Diuk-Wasser, M. A., Kraiczy, P., Anna M. Blom & Lin, Y. P., 2020 Mar, In : Ticks and Tick-borne Diseases. 11, 2, 101354.

    Research output: Contribution to journalArticle

  4. Gain-of-function mutation in complement C2 protein identified in a patient with aHUS

    Urban, A., Volokhina, E., Felberg, A., Stasiłojć, G., Anna M. Blom, Jongerius, I., van den Heuvel, L., Thiel, M., Ołdziej, S., Arjona, E., de Córdoba, S. R. & Okrój, M., 2020 Feb 28, In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalLetter

  5. Apolipoprotein E triggers complement activation in joint synovial fluid of rheumatoid arthritis patients by binding C1q

    Leonie M. Vogt, Kwasniewicz, E., Talens, S., Scavenius, C., Bielecka, E., Ekdahl, K. N., Enghild, J. J., Mörgelin, M., Tore Saxne, Potempa, J. & Anna M. Blom, 2020, In : Journal of Immunology. 204, 10, p. 2779-2790 12 p.

    Research output: Contribution to journalArticle

  6. Calcein release assay as a method for monitoring serum complement activity during monoclonal antibody therapy in patients with B-cell malignancies

    Stasiłojć, G., Felberg, A., Urban, A., Kowalska, D., Ma, S., Anna M. Blom, Lundin, J., Österborg, A. & Okrój, M., 2020, In : Journal of Immunological Methods. 476, p. 1-5 112675.

    Research output: Contribution to journalArticle

  7. 2019
  8. C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections

    Serena Bettoni, Shaughnessy, J., Maziarz, K., David Ermert, Gulati, S., Zheng, B., Mörgelin, M., Jacobsson, S., Kristian Riesbeck, Unemo, M., Ram, S. & Anna M. Blom, 2019 Dec 5, In : JCI Insight. 4, 23, e131886.

    Research output: Contribution to journalArticle

  9. Noncanonical immunomodulatory activity of complement regulator C4BP(β-) limits the development of lupus nephritis

    Luque, A., Serrano, I., Ripoll, E., Malta, C., Gomà, M., Anna M. Blom, Grinyó, J. M., Rodríguez de Córdoba, S., Torras, J. & Aran, J. M., 2019 Nov 6, In : Kidney International.

    Research output: Contribution to journalArticle

  10. The hijackers guide to escaping complement: Lessons learned from pathogens

    D. Ermert, Ram, S. & Laabei, M., 2019 Oct, In : Molecular Immunology. 114, p. 49-61 13 p.

    Research output: Contribution to journalReview article

  11. The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus

    David Ermert, Laabei, M., Weckel, A., Mörgelin, M., Martin Lundqvist, Lars Björck, Ram, S., Sara Linse & Anna M. Blom, 2019 Jun 4, In : Frontiers in Immunology. 10, JUN, 1230.

    Research output: Contribution to journalArticle

  12. Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment

    Singel, K. L., Emmons, T. R., Khan, A. N. H., Mayor, P. C., Shen, S., Wong, J. T., Morrell, K., Eng, K. H., Mark, J., Bankert, R. B., Matsuzaki, J., Koya, R. C., Blom, A. M., McLeish, K. R., Qu, J., Ram, S., Moysich, K. B., Abrams, S. I., Odunsi, K., Zsiros, E. & 1 others, Segal, B. H., 2019 Feb 7, In : JCI Insight. 4, 5, e122311.

    Research output: Contribution to journalArticle

  13. C3 glomerulopathy — understanding a rare complement-driven renal disease

    Smith, R. J. H., Appel, G. B., Anna M. Blom, Cook, H. T., D’Agati, V. D., Fakhouri, F., Fremeaux-Bacchi, V., Józsi, M., Kavanagh, D., Lambris, J. D., Noris, M., Pickering, M. C., Remuzzi, G., de Córdoba, S. R., Sethi, S., Van der Vlag, J., Zipfel, P. F. & Nester, C. M., 2019 Jan 28, In : Nature Reviews Nephrology.

    Research output: Contribution to journalReview article

  14. Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies

    Laabei, M. & David Ermert, 2019, In : Journal of Innate Immunity. 11, 1, p. 3-12

    Research output: Contribution to journalArticle

  15. Measuring plasma C4D to monitor immune complexes in lupus nephritis

    Kraaij, T., Sara C. Nilsson, Van Kooten, C., Okrój, M., Anna M. Blom & Teng, Y. O., 2019, In : Lupus Science and Medicine. 6, 1, e000326.

    Research output: Contribution to journalArticle

  16. Mutations resulting in the formation of hyperactive complement convertases support cytocidal effect of anti-CD20 immunotherapeutics

    Felberg, A., Urban, A., Borowska, A., Stasiłojć, G., Taszner, M., Hellmann, A., Anna Maria Blom & Okrój, M., 2019, In : Cancer Immunology, Immunotherapy. 68, 4, p. 587-598

    Research output: Contribution to journalArticle

  17. ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development

    Mastellos, D. C., Blom, A. M., Connolly, E. S., Daha, M. R., Geisbrecht, B. V., Ghebrehiwet, B., Gros, P., Hajishengallis, G., Holers, V. M., Huber-Lang, M., Kinoshita, T., Mollnes, T. E., Montgomery, R. A., Morgan, B. P., Nilsson, B., Pio, R., Ricklin, D., Risitano, A. M., Taylor, R. P., Mantovani, A. & 2 others, Ioannidis, J. P. A. & Lambris, J. D., 2019, In : Nature Immunology. 20, 11, p. 1409-1413 5 p.

    Research output: Contribution to journalDebate/Note/Editorial

  18. The noncoding RNA nc886 regulates PKR signaling and cytokine production in human cells

    Golec, E., Lind, L., Qayyum, M., Anna M. Blom & Ben C. King, 2019, In : Journal of Immunology. 202, 1, p. 131-141 11 p.

    Research output: Contribution to journalArticle

  19. 2018
  20. Analysis of C3 gene variants in patients with idiopathic recurrent spontaneous pregnancy loss

    Mohlin, F. C., Gros, P., Mercier, E., Gris, J. C. R. & Anna M. Blom, 2018 Aug, In : Frontiers in Immunology. 9, AUG, 1813.

    Research output: Contribution to journalArticle

  21. Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA

    Yokoyama, M., Stevens, E., Laabei, M., Bacon, L., Heesom, K., Bayliss, S., Ooi, N., O'Neill, A. J., Murray, E., Williams, P., Lubben, A., Reeksting, S., Meric, G., Pascoe, B., Sheppard, S. K., Recker, M., Hurst, L. D. & Massey, R. C., 2018 Jul 18, In : Genome Biology. 19, 1, 94.

    Research output: Contribution to journalArticle

  22. Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo

    Nandakumar, K. S., Mattias Collin, Happonen, K. E., Lundström, S. L., Croxford, A. M., Xu, B., Zubarev, R. A., Rowley, M. J., Anna M. Blom, Kjellman, C. & Holmdahl, R., 2018 Jul 16, In : Frontiers in Immunology. 9, 1623.

    Research output: Contribution to journalArticle

  23. Human igg increases virulence of streptococcus pyogenes through complement evasion

    David Ermert, Weckel, A., Michal Magda, Mörgelin, M., Shaughnessy, J., Rice, P. A., Lars Björck, Ram, S. & Anna M. Blom, 2018 May 15, In : Journal of Immunology. 200, 10, p. 3495-3505 11 p.

    Research output: Contribution to journalArticle

  24. Overactivity of alternative pathway convertases in patients with complement-mediated renal diseases

    Michels, M. A. H. M., van de Kar, N. C. A. J., Okrój, M., Anna M. Blom, van Kraaij, S. A. W., Volokhina, E. B., van den Heuvel, L. P. W. J. & COMBAT Consortium, 2018 Apr 4, In : Frontiers in Immunology. 9, APR, 612.

    Research output: Contribution to journalArticle

  25. Genetic predisposition to infection in a case of atypical hemolytic uremic syndrome

    Van Den Heuvel, L., Kristian Riesbeck, El Tahir, O., Gracchi, V., Mariann Kremlitzka, Morré, S. A., Van Furth, A. M., Singh, B., Okrój, M., Van De Kar, N., Anna M. Blom & Volokhina, E., 2018 Jan 1, In : Journal of Human Genetics. 63, 1, p. 93-96 4 p.

    Research output: Contribution to journalArticle

  26. Complement C4d-specific antibodies for the diagnosis of lung cancer

    Ajona, D., Okrój, M., Pajares, M. J., Agorreta, J., Lozano, M. D., Zulueta, J. J., Verri, C., Roz, L., Sozzi, G., Pastorino, U., Massion, P. P., Montuenga, L. M., Anna M. Blom & Pio, R., 2018, In : Oncotarget. 9, 5, p. 6346-6355 10 p.

    Research output: Contribution to journalArticle

  27. Functional analyses of rare genetic variants in complement component C9 identified in patients with age-related macular degeneration

    Mariann Kremlitzka, Geerlings, M. J., De Jong, S., Bakker, B., Sara C. Nilsson, Fauser, S., Hoyng, C. B., De Jong, E. K., Den Hollander, A. I. & Anna M. Blom, 2018, In : Human Molecular Genetics. 27, 15, p. 2678-2688 11 p.

    Research output: Contribution to journalArticle

  28. Short leucine-rich proteoglycans modulate complement activity and increase killing of the respiratory pathogen moraxella catarrhalis

    Laabei, M., Liu, G., David Ermert, Lambris, J. D., Kristian Riesbeck & Anna M. Blom, 2018, In : Journal of Immunology. 201, 9, p. 2721-2730 10 p.

    Research output: Contribution to journalArticle

  29. 2017
  30. Complement C3 Associates With Incidence of Diabetes, but No Evidence of a Causal Relationship

    Yan Borné, Iram Faqir Muhammad, Lorés-Motta, L., Bo Hedblad, Peter M. Nilsson, Olle Melander, de Jong, E. K., Anna M. Blom, den Hollander, A. I. & Gunnar Engström, 2017 Dec 1, In : The Journal of clinical endocrinology and metabolism. 102, 12, p. 4477-4485 9 p.

    Research output: Contribution to journalArticle

  31. Factor H–IgG chimeric proteins as a therapeutic approach against the gram-positive bacterial pathogen Streptococcus pyogenes

    Anna M. Blom, Michal Magda, Kohl, L., Shaughnessy, J., Lambris, J. D., Ram, S. & David Ermert, 2017 Dec 1, In : Journal of Immunology. 199, 11, p. 3828-3839 12 p.

    Research output: Contribution to journalArticle

  32. The structural basis for complement inhibition by gigastasin, a protease inhibitor from the giant Amazon leech

    Pang, S. S., Wijeyewickrema, L. C., Hor, L., Tan, S., Lameignere, E., Conway, E. M., Anna M. Blom, Mohlin, F. C., Liu, X., Payne, R. J., Whisstock, J. C. & Pike, R. N., 2017 Dec 1, In : Journal of Immunology. 199, 11, p. 3883-3891 9 p.

    Research output: Contribution to journalArticle

  33. C4b-Binding Protein

    Okrój, M. & Anna M. Blom, 2017 Oct 19, The Complement FactsBook: Second Edition. Elsevier, p. 251-259 9 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  34. Factor I

    Okrój, M. & Anna M. Blom, 2017 Oct 19, The Complement FactsBook: Second Edition. Elsevier, p. 147-154 8 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  35. Dual transcriptome of the immediate neutrophil and Candida albicans interplay

    Niemiec, M. J., Grumaz, C., David Ermert, Desel, C., Shankar, M., Lopes, J. P., Mills, I. G., Stevens, P., Sohn, K. & Urban, C. F., 2017 Sep 6, In : BMC Genomics. 18, 1, 696.

    Research output: Contribution to journalArticle

  36. The complement system as a potential therapeutic target in rheumatic disease

    Trouw, L. A., Pickering, M. C. & Anna M. Blom, 2017 Sep 1, In : Nature Reviews Rheumatology. 13, 9, p. 538-547 10 p.

    Research output: Contribution to journalReview article

  37. Activation of complement by pigment epithelium-derived factor in rheumatoid arthritis

    Leonie M. Vogt, Talens, S., Kwasniewicz, E., Scavenius, C., André Struglics, Enghild, J. J., Tore Saxne & Anna M. Blom, 2017 Aug 1, In : Journal of Immunology. 199, 3, p. 1113-1121 9 p.

    Research output: Contribution to journalArticle

  38. Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier

    Kober, A. C., Manavalan, A. P. C., Tam-Amersdorfer, C., Holmér, A., Saeed, A., Fanaee-Danesh, E., Zandl, M., Albrecher, N. M., Björkhem, I., Kostner, G. M., Björn Dahlbäck & Panzenboeck, U., 2017 Jun 1, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 6, p. 573-588 16 p.

    Research output: Contribution to journalArticle

  39. The functional effect of rare variants in complement genes on C3b degradation in patients with age-related macular degeneration

    Geerlings, M. J., Mariann Kremlitzka, Bakker, B., Sara C. Nilsson, Saksens, N. T., Lechanteur, Y. T. E., Pauper, M., Corominas, J., Fauser, S., Hoyng, C. B., Anna Blom, De Jong, E. K. & den Hollander, A. I., 2017 Jan 1, In : JAMA Ophthalmology. 135, 1, p. 39-46 8 p.

    Research output: Contribution to journalArticle

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