Division of Molecular Medicine and Gene Therapy

Organisational unit: Division

Description

Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in order to dissect the molecular regulation of hematopoiesis. Our mission is to translate this information into clinical contexts to advance the full potential of regenerative medicine.

Research

The department focuses on research that aims to develop gene therapy for hematopoietic cells using viral vectors. Hematopoiesis, in particular the genetic control of hematopoietic cell proliferation and differentiation is also studied in human cell cultures and transgenic mouse model systems.

Recent research outputs

Marie E. Jönsson, Ludvik Brattås, P., Gustafsson, C., Petri, R., David Yudovich, Karolina Pircs, Verschuere, S., Madsen, S., Jenny Hansson, Jonas Larsson, Månsson, R., Meissner, A. & Johan Jakobsson, 2019 Jul 18, In : Nature Communications. 10, 1, 3182.

Research output: Contribution to journalArticle

Katri, A., Dąbrowska, A., Löfvall, H., Karsdal, M. A., Andreassen, K. V., Thudium, C. S. & Henriksen, K., 2019 Jun 5, In : Osteoarthritis and Cartilage.

Research output: Contribution to journalArticle

Zahra Masoumi, Maes, G. E., Herten, K., Cortés-Calabuig, Á., Abdul Ghani Alattar, Hanson, E., Lena Erlandsson, Mezey, E., Mattias Magnusson, Vermeesch, J. R., Mary Familari & Stefan R. Hansson, 2019 Apr 25, In : International Journal of Molecular Sciences. 20, 8, 2038.

Research output: Contribution to journalArticle

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