Division of Molecular Medicine and Gene Therapy

Organisational unit: Division

Description

Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in order to dissect the molecular regulation of hematopoiesis. Our mission is to translate this information into clinical contexts to advance the full potential of regenerative medicine.

Research

The department focuses on research that aims to develop gene therapy for hematopoietic cells using viral vectors. Hematopoiesis, in particular the genetic control of hematopoietic cell proliferation and differentiation is also studied in human cell cultures and transgenic mouse model systems.

Recent research outputs

Ramprasad Ramakrishnan, Pablo Peña-Martínez, Agarwal, P., Rodriguez-Zabala, M., Marion Chapellier, Högberg, C., Eriksson, M., David Yudovich, Shah, M., Mats Ehinger, Björn Nilsson, Jonas Larsson, Anna Hagström-Andersson, Ebert, B. L., Bhatia, R. & Marcus Järås, 2020 May 26, In : Cell Reports. 31, 8, 107684.

Research output: Contribution to journalArticle

Xiaojie Xian, Moraghebi, R., Löfvall, H., Fasth, A., Henriksen, K., Johan Richter, Niels Bjarne Woods & Ilana Moscatelli, 2020 May 15, In : Stem Cell Research & Therapy. 11, 179.

Research output: Contribution to journalArticle

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