Epilepsy Center

1. 2019
2. The emerging role of omega-3 fatty acids as a therapeutic option in neuropsychiatric disorders

   Reimers, A. & Hanna Ljung, 2019 Jun 24, In : Therapeutic advances in psychopharmacology. 9

   Research output: Contribution to journal › Review article

3. Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy

   Pitkänen, A., Henshall, D. C., Cross, J. H., Guerrini, R., Jozwiak, S., Merab Kokaia, Simonato, M., Sisodiya, S. & Mifsud, J., 2019, In : Epilepsia.

   Research output: Contribution to journal › Article

4. Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy

   Paolone, G., Falcicchia, C., Lovisari, F., Merab Kokaia, Bell, W. J., Fradet, T., Barbieri, M., Wahlberg, L. U., Emerich, D. F. & Simonato, M., 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 11, p. 2144-2156 13 p.

   Research output: Contribution to journal › Article

5. Therapeutic Potential of Iridoid Derivatives: Patent Review.

   Muhammad Liaquat Raza, Hussain, H., Green, I. R., Saleem, M. & Nazir, M., 2019, In : Inventions. 4, 2, 29.

   Research output: Contribution to journal › Review article

6. Unilateral ex vivo gene therapy by GDNF in epileptic rats

   Nanobashvili, A., Esbjörn Melin, Emerich, D., Tornøe, J., Simonato, M., Wahlberg, L. & Merab Kokaia, 2019, In : Gene Therapy. 26, 3-4, p. 65-74

   Research output: Contribution to journal › Article

7. 2018
8. Dynamic interaction of local and transhemispheric networks is necessary for progressive intensification of hippocampal seizures

   Fredrik Berglind, My Andersson & Merab Kokaia, 2018 Dec 1, In : Scientific Reports. 8, 1, 5669.

   Research output: Contribution to journal › Article

9. Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery

   J. Wickham, Brödjegård, N. G., Vighagen, R., Pinborg, L. H., J. Bengzon, Woldbye, D. P. D., M. Kokaia & M. Andersson, 2018 Dec 1, In : Scientific Reports. 8, 1, 4158.

   Research output: Contribution to journal › Article

10. PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity

    Adelöf, J., My Andersson, Porritt, M., Petersen, A., Zetterberg, M., Wiseman, J. & Hernebring, M., 2018 Nov 6, In : BMC Neuroscience. 19, 1, 17.

    Research output: Contribution to journal › Article

11. Decreased post-synaptic density-95 protein expression on dendrites of newborn neurons following CX3CR1 modulation in the epileptogenic adult rodent brain

    Ali, I., Avdic, U., Chugh, D. & Christine T. Ekdahl, 2018 Oct 30, In : Cellular and Molecular Immunology. 15, 4, p. 414-417 4 p.

    Research output: Contribution to journal › Letter

12. The neuroprotective effects of 17β-estradiol pretreatment in a model of neonatal hippocampal injury induced by trimethyltin

    Marchese, E., Corvino, V., Valentina Di Maria, Furno, A., Giannetti, S., Cesari, E., Lulli, P., Michetti, F. & Geloso, M. C., 2018 Oct 26, In : Frontiers in Cellular Neuroscience. 12, 385.

    Research output: Contribution to journal › Article

13. Test-specific differences in verbal memory assessments used prior to surgery in temporal lobe epilepsy

    Hanna Ljung, Maria Compagno Strandberg, Isabella M Björkman-Burtscher, Elia Psouni & Kristina Källén, 2018 Oct, In : Epilepsy and Behavior. 87, p. 18-24 7 p.

    Research output: Contribution to journal › Article

14. Spatiotemporal pattern of Wnt-canonical pathway in dorsal telencephalic organoids.

    Ana Gonzalez Ramos, Marshall, J. & Mason, J. O., 2018 Jul 6, (Unpublished).

    Research output: Contribution to conference › Poster

15. Microscopic diffusion anisotropy reveals microstructural heterogeniety of malformations of cortical development associated with wpilwpsy: a b-tensor encoding study at 7T

    Björn Lampinen, Ariadne Zampeli, Filip Szczepankiewicz, MARIA COMPAGNO STRANDBERG, Kristina Källén, Isabella Björkman-Burtscher & Markus Nilsson, 2018 Jun 16.

    Research output: Contribution to conference › Abstract

16. Impact of donor chest radiography on clinical outcome after lung transplantation

    Gracijela Bozovic, Adlercreutz, C., Isabella M Björkman-burtscher, Peter Reinstrup, Richard Ingemansson, Skansebo, E. & Mats Geijer, 2018 May 1, In : Acta radiologica open. 7, 6, 7 p.

    Research output: Contribution to journal › Article

17. Preserved function of afferent parvalbumin-positive perisomatic inhibitory synapses of dentate granule cells in rapidly kindled mice

    Hansen, M. G., Ledri, L. N., Deniz Kirik, Merab Kokaia & Marco Ledri, 2018 Jan 9, In : Frontiers in Cellular Neuroscience. 11, 433.

    Research output: Contribution to journal › Article

18. Bridging the gap in translational epilepsy research - A patient brain tissue platform for validating animal data

    Jenny Wickham, 2018, Lund: Lund University, Faculty of Medicine. 79 p.

    Research output: Thesis › Doctoral Thesis (compilation)

19. Immune responses and synaptic protein expression in epilepsy

    Avdic, U., 2018, Lund: Lund University, Faculty of Medicine. 103 p.

    Research output: Thesis › Doctoral Thesis (compilation)

20. Nonconvulsive status epilepticus in rats leads to brain pathology

    Avdic, U., Matilda Ahl, Chugh, D., Ali, I., Chary, K., Sierra, A. & Christine T. Ekdahl, 2018, In : Epilepsia. 59, 5, p. 945-958

    Research output: Contribution to journal › Article

21. Predictors of Verbal Memory Deficits from Temporal Lobe Surgery in Epilepsy. Improving patient selection by investigation of methods used for predicting verbal memory following surgery.

    Hanna Ljung, 2018, Lund: Lund University, Faculty of Medicine. 61 p.

    Research output: Thesis › Doctoral Thesis (compilation)

22. Response: Memory decline from hippocampal electrodes? Let's not forget statistics and study design

    Hanna Ljung, Maria Strandberg, Johan Bengzon & Kristina Källén, 2018, In : Epilepsia. 59, 2, p. 503-504 2 p.

    Research output: Contribution to journal › Debate/Note/Editorial

23. 2017
24. Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

    Avaliani, N., Pfisterer, U., Andreas Heuer, Malin Parmar, Merab Kokaia & My Andersson, 2017 Nov 26, In : Stem Cells International. 2017, 9 p., 5718608.

    Research output: Contribution to journal › Article

25. Altered chloride homeostasis decreases the action potential threshold and increases hyperexcitability in hippocampal neurons

    Sørensen, A. T., Marco Ledri, Melis, M., Ledri, L. N., My Andersson & Merab Kokaia, 2017 Nov 1, In : eNeuro. 4, 6, e0172-17.2017.

    Research output: Contribution to journal › Article

26. Epilepsy and optogenetics: Can seizures be controlled by light?

    Tönnesen, J. & Merab Kokaia, 2017 Jul 15, In : Clinical Science. 131, 14, p. 1605-1616 12 p.

    Research output: Contribution to journal › Review article

27. Autoimmunity and mental health in William’s syndrome

    Tania Ramos-Moreno, 2017 Jan 1, Advances in Health and Disease. Lowell, D. (ed.). Nova Science Publishers, Inc., Vol. 2. p. 81-114 34 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter

28. Common data elements and data management: Remedy to cure underpowered preclinical studies

    Lapinlampi, N., Esbjörn Melin, Aronica, E., Bankstahl, J. P., Becker, A., Bernard, C., Gorter, J. A., Gröhn, O., Lipsanen, A., Lukasiuk, K., Löscher, W., Paananen, J., Ravizza, T., Roncon, P., Simonato, M., Vezzani, A., Merab Kokaia & Pitkänen, A., 2017 Jan 1, In : Epilepsy Research. 129, p. 87-90 4 p.

    Research output: Contribution to journal › Article

29. Impact of generic substitution on levetiracetam serum concentration - a prospective study in an outpatient setting

    Patrik Olsson, Arne Reimers, Nilsson, J., Hoff, E., Lundgren, A., MARIA COMPAGNO STRANDBERG, Reis, M. & Kristina Kallen, 2017.

    Research output: Contribution to conference › Abstract

30. Toward an Optogenetic Therapy for Epilepsy

    Tönnesen, J., Marco Ledri & Merab Kokaia, 2017, Optogenetics: From Neuronal Function to Mapping and Disease Biology. Appasani, K. (ed.). Cambridge: Cambridge University Press, p. 292-307

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter

31. Verbal memory decline from hippocampal depth electrodes in temporal lobe surgery for epilepsy

    Hanna Ljung, Nordlund, A., MARIA STRANDBERG, Johan Bengzon & Kristina Källén, 2017, In : Epilepsia. 58, 12, p. 2143-2152

    Research output: Contribution to journal › Article

32. 2016

33. DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue

    Avaliani, N., M. Andersson, Runegaard, A. H., Woldbye, D. & M. Kokaia, 2016 Oct 1, In : Gene Therapy. 23, 10, p. 760-766 7 p.

    Research output: Contribution to journal › Article

34. Advances in the development of biomarkers for epilepsy

    Pitkänen, A., Löscher, W., Vezzani, A., Becker, A. J., Simonato, M., Lukasiuk, K., Gröhn, O., Bankstahl, J. P., Friedman, A., Aronica, E., Gorter, J. A., Ravizza, T., Sisodiya, S. M., Merab Kokaia & Beck, H., 2016 Jul 1, In : Lancet Neurology. 15, 8, p. 843-856 14 p.

    Research output: Contribution to journal › Review article

35. Immune response in the eye following epileptic seizures

    Matilda Ahl, Avdic, U., Skoug, C., Ali, I., Chugh, D., Ulrica Englund Johansson & Christine Ekdahl Clementson, 2016 Jun 27, In : Journal of Neuroinflammation. 13, 1, 155.

    Research output: Contribution to journal › Article

36. Optogenetic control of human neurons in organotypic brain cultures

    My Andersson, Avaliani, N., Andreas Svensson, Jenny Wickham, Pinborg, L. H., Jespersen, B., Christiansen, S. H., Johan Bengzon, Woldbye, D. P. D. & Merab Kokaia, 2016 Apr 21, In : Scientific Reports. 6, 24818.

    Research output: Contribution to journal › Article

37. Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry

    Fredrik Berglind, 2016, Experimental Epilepsy Group. 71 p.

    Research output: Thesis › Doctoral Thesis (compilation)

38. Short-term grafting of human neural stem cells: Electrophysiological properties and motor behavioral amelioration in experimental Parkinson’s disease

    Martínez-Serrano, A., Pereira, M. P., Avaliani, N., Nelke, A., Merab Kokaia & Tania Ramos-Moreno, 2016, In : Cell Transplantation. 25, 12, p. 2083-2097 15 p.

    Research output: Contribution to journal › Article

39. Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors.

    Nikitidou, L., Esbjörn Melin, Christiansen, S. H., Gøtzsche, C. R., Cifra, A., Woldbye, D. P. D. & Merab Kokaia, 2016, In : Neurobiology of Disease. 86, nov 19, p. 52-61

    Research output: Contribution to journal › Article

40. 2015

41. Är epileptiker extra kreativa?

    Kristina Kallen, 2015 Sep 14, In : Forskning & framsteg.

    Research output: Contribution to journal › Article

42. Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2.

    Chugh, D., Ali, I., Anahita Bakochi, Bahonjic, E., Etholm, L. & Christine Ekdahl Clementson, 2015, In : PLoS ONE. 10, 7, e0132366.

    Research output: Contribution to journal › Article

43. Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy

    Avaliani, N., 2015, Department of Clinical Sciences, Lund University. 75 p.

    Research output: Thesis › Doctoral Thesis (compilation)

44. Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus.

    Marco Ledri, Sørensen, A. T., Grönning Madsen, M., Christiansen, S. H., Ledri, L. N., Cifra, A., Johan Bengzon, Lindberg, E., Pinborg, L. H., Jespersen, B., Gøtzsche, C. R., Woldbye, D. P. D., My Andersson & Merab Kokaia, 2015, In : Journal of Neuroscience. 35, 26, p. 9622-9631

    Research output: Contribution to journal › Article

45. 2014

46. A compact multifunctional microfluidic platform for exploring cellular dynamics in real-time using electrochemical detection

    Zor, K., Heiskanen, A., Caviglia, C., Vergani, M., Landini, E., Shah, F., Carminati, M., Martinez-Serrano, A., Ramos Moreno, T., Kokaia, M., Benayahu, D., Keresztes, Z., Papkovsky, D., Wollenberger, U., Svendsen, W. E., Dimaki, M., Ferrari, G., Raiteri, R., Sampietro, M., Dufva, M. & 1 othersEmneus, J., 2014, In : RSC Advances. 4, 109, p. 63761-63771

    Research output: Contribution to journal › Article

47. Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity.

    Marco Ledri, Grönning Madsen, M., Nikitidou, L., Deniz Kirik & Merab Kokaia, 2014, In : Journal of Neuroscience. 34, 9, p. 3364-3377

    Research output: Contribution to journal › Article

48. How Might Novel Technologies Such as Optogenetics Lead to Better Treatments in Epilepsy?

    Krook-Magnuson, E., Marco Ledri, Soltesz, I. & Merab Kokaia, 2014, Issues in Clinical Epileptology: A View From the Bench. Scharfman, H. E. & Buckmaster, P. S. (eds.). Springer, Vol. 813. p. 319-336 (Advances in Experimental Medicine and Biology; vol. 813).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter

49. Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.

    Fredrik Berglind, Marco Ledri, Sørensen, A. T., Nikitidou, L., Melis, M., Bielefeld, P., Deniz Kirik, Deisseroth, K., My Andersson & Merab Kokaia, 2014, In : Neurobiology of Disease. 65, p. 133-141

    Research output: Contribution to journal › Article

50. Optogenetics reveal delayed afferent synaptogenesis on grafted human induced pluripotent stem cell-derived neural progenitors.

    Avaliani, N., Toft Sörensen, A., Marco Ledri, Johan Bengzon, Koch, P., Brüstle, O., Deisseroth, K., My Andersson & Merab Kokaia, 2014, In : Stem Cells. 32, 12, p. 3088-3098

    Research output: Contribution to journal › Article

51. Quantitative mapping of the local and extrinsic sources of GABA and Reelin to the layer Ia neuropil in the adult rat neocortex

    Tania Ramos Moreno & Clasca, F., 2014, In : Brain Structure and Function. 219, 5, p. 1639-1657

    Research output: Contribution to journal › Article

52. WONOEP appraisal: Optogenetic tools to suppress seizures and explore the mechanisms of epileptogenesis

    Ritter, L. M., Golshani, P., Takahashi, K., Dufour, S., Valiante, T. & Merab Kokaia, 2014, In : Epilepsia. 55, 11, p. 1693-1702

    Research output: Contribution to journal › Article

53. 2013

54. Epilepsy therapy development: Technical and methodologic issues in studies with animal models

    Galanopoulou, A. S., Merab Kokaia, Loeb, J. A., Nehlig, A., Pitkanen, A., Rogawski, M. A., Staley, K. J., Whittemore, V. H. & Dudek, F. E., 2013, In : Epilepsia. 54, p. 13-23

    Research output: Contribution to journal › Article

55. 2012

56. Altered profile of basket cell afferent synapses in hyper-excitable dentate gyrus revealed by optogenetic and two-pathway stimulations.

    Marco Ledri, Nikitidou, L., Erdelyi, F., Szabo, G., Deniz Kirik, Deisseroth, K. & Merab Kokaia, 2012, In : European Journal of Neuroscience. 36, 1, p. 1971-1983

    Research output: Contribution to journal › Article

57. Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures

    Gotzsche, C. R., Nikitidou, L., Toft Sörensen, A., Olesen, M. V., Sorensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, D. P. D. & Merab Kokaia, 2012, In : Neurobiology of Disease. 45, 1, p. 288-296

    Research output: Contribution to journal › Article

58. Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer's Disease

    Biscaro, B., Olle Lindvall, Tesco, G., Christine Ekdahl Clementson & Nitsch, R. M., 2012, In : Neurodegenerative Diseases. 9, 4, p. 187-198

    Research output: Contribution to journal › Article