Epilepsy Center

Organisational unit: Division

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  1. 2020
  2. Early infantile epileptic encephalopathy due to biallelic pathogenic variants in PIGQ: Report of seven new subjects and review of the literature

    Devon L. Johnstone, Thi Tuyet Mai Nguyen, Jessica Zambonin, Kristin D. Kernohan, Anik St-Denis, Nissan V. Baratang, Taila Hartley, Michael T. Geraghty, Julie Richer, Jacek Majewski, Eric Bareke, Andrea Guerin, Manuela Pendziwiat, Loren D.M. Pena, Hilde M.H. Braakman, Karen W. Gripp, Andrew C. Edmondson, Miao He, Rebecca C. Spillmann, Erik A. Eklund & 4 others, Allan Bayat, Hugh J. McMillan, Kym M. Boycott & Philippe M. Campeau, 2020 Nov, In : Journal of Inherited Metabolic Disease. 43, 6, p. 1321-1332 12 p.

    Research output: Contribution to journalArticle

  3. Predominant and novel de novo variants in 29 individuals with ALG13 deficiency: Clinical description, biomarker status, biochemical analysis, and treatment suggestions

    Undiagnosed Diseases Network Undiagnosed Diseases Network, Bobby G Ng, Erik Eklund & Hudson H. Freeze, 2020 Nov, In : Journal of Inherited Metabolic Disease. 43, 6, p. 1333-1348 16 p.

    Research output: Contribution to journalArticle

  4. Neuropsychological outcome after cardiac arrest: A prospective case control sub-study of the Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest trial (TTM2)

    Erik Blennow Nordström, Gisela Lilja, Susanna Vestberg, Susann Ullén, Hans Friberg, Niklas Nielsen, Katarina Heimburg, Lars Evald, Marco Mion, Magnus Segerström, Anders M. Grejs, Thomas Keeble, Hans Kirkegaard, Hanna Ljung, Sofia Rose, Matthew P. Wise, Christian Rylander, Johan Undén & Tobias Cronberg, 2020 Oct 7, In : BMC Cardiovascular Disorders. 20, 1, 439.

    Research output: Contribution to journalArticle

  5. Evidence-based Anti-seizure Monotherapy in Newly Diagnosed Epilepsy: a New Approach

    MARIA COMPAGNO STRANDBERG, Karin Söderberg-Löfdal, Elin Kimland, Maria Dahlin & Kristina Kallen, 2020 Oct, In : Acta Neurologica Scandinavica. 142, 4, p. 323-332 10 p.

    Research output: Contribution to journalArticle

  6. Professionen har varit snabb att ta till sig nya läkemedel

    Kristina Kallen, MARIA COMPAGNO STRANDBERG & Karin Söderberg-Löfdal, 2020 Oct, In : Läkartidningen.

    Research output: Contribution to journalDebate/Note/Editorial

  7. Advancing gene therapy for epilepsy. Translational pre-clinical studies with neuropeptide Y and glial cell-line derived neurotrophic factor.

    Esbjörn Melin, 2020, Lund: Lund University, Faculty of Medicine. 100 p.

    Research output: ThesisDoctoral Thesis (compilation)

  8. Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons

    Valentina Di Maria, Marine Moindrot, Martin Ryde, Antonino Bono, Luis Quintino & Marco Ledri, 2020, In : Frontiers in Molecular Neuroscience. 13, 168.

    Research output: Contribution to journalArticle

  9. Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats

    Julia Alicja Szczygieł, Kira Iben Danielsen, Esbjörn Melin, Søren Hofman Rosenkranz, Stanislava Pankratova, Annika Ericsson, Karin Agerman, Merab Kokaia & David Paul Drucker Woldbye, 2020, In : Frontiers in Molecular Neuroscience. 13, 232.

    Research output: Contribution to journalArticle

  10. 2019
  11. Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy

    Esbjörn Melin, Avtandil Nanobashvili, Una Avdic, Casper R. Gøtzsche, My Andersson, David P.D. Woldbye & Merab Kokaia, 2019 Dec 13, In : Molecular Therapy - Methods and Clinical Development. 15, p. 179-193 15 p.

    Research output: Contribution to journalArticle

  12. In vivo assessment of anticoagulant and antiplatelet effects of Syzygium cumini leaves extract in rabbits

    Ahad Abdul Rehman, Azra Riaz, Muhammad Arif Asghar, Muhammad Liaquat Raza, Shadab Ahmed & Kamran Khan, 2019 Sep 3, In : BMC Complementary and Alternative Medicine. 19, 1, 236.

    Research output: Contribution to journalArticle

  13. Immune profile in blood following non-convulsive epileptic seizures in rats

    Una Avdic, Matilda Ahl, Maria Öberg & Christine T. Ekdahl, 2019 Jan 1, In : Frontiers in Neurology. 10, JUL, 701.

    Research output: Contribution to journalArticle

  14. Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy

    Asla Pitkänen, David C. Henshall, J. Helen Cross, Renzo Guerrini, Sergiusz Jozwiak, Merab Kokaia, Michele Simonato, Sanjay Sisodiya & Janet Mifsud, 2019, In : Epilepsia.

    Research output: Contribution to journalArticle

  15. Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons

    Shashank Vasudevan, Janko Kajtez, Ada Ioana Bunea, Ana Gonzalez-Ramos, Tania Ramos-Moreno, Arto Heiskanen, Merab Kokaia, Niels B. Larsen, Alberto Martínez-Serrano, Stephan S. Keller & Jenny Emnéus, 2019, In : Advanced Science. 6, 24, 1902011.

    Research output: Contribution to journalArticle

  16. Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy

    Giovanna Paolone, Chiara Falcicchia, Francesca Lovisari, Merab Kokaia, William J. Bell, Tracie Fradet, Mario Barbieri, Lars U. Wahlberg, Dwaine F. Emerich & Michele Simonato, 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 11, p. 2144-2156 13 p.

    Research output: Contribution to journalArticle

  17. Therapeutic Potential of Iridoid Derivatives: Patent Review.

    Muhammad Liaquat Raza, Hidayat Hussain, Ivan R. Green, Muhammad Saleem & Mamona Nazir, 2019, In : Inventions. 4, 2, 29.

    Research output: Contribution to journalReview article

  18. Unilateral ex vivo gene therapy by GDNF in epileptic rats

    Avtandil Nanobashvili, Esbjörn Melin, Dwaine Emerich, Jens Tornøe, Michele Simonato, Lars Wahlberg & Merab Kokaia, 2019, In : Gene Therapy. 26, 3-4, p. 65-74

    Research output: Contribution to journalArticle

  19. 2018
  20. Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery

    J. Wickham, N. G. Brödjegård, R. Vighagen, L. H. Pinborg, J. Bengzon, D. P.D. Woldbye, M. Kokaia & M. Andersson, 2018 Dec 1, In : Scientific Reports. 8, 1, 4158.

    Research output: Contribution to journalArticle

  21. PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity

    Julia Adelöf, My Andersson, Michelle Porritt, Anne Petersen, Madeleine Zetterberg, John Wiseman & Malin Hernebring, 2018 Nov 6, In : BMC Neuroscience. 19, 1, 17.

    Research output: Contribution to journalArticle

  22. The neuroprotective effects of 17β-estradiol pretreatment in a model of neonatal hippocampal injury induced by trimethyltin

    Elisa Marchese, Valentina Corvino, Valentina Di Maria, Alfredo Furno, Stefano Giannetti, Eleonora Cesari, Paola Lulli, Fabrizio Michetti & Maria Concetta Geloso, 2018 Oct 26, In : Frontiers in Cellular Neuroscience. 12, 385.

    Research output: Contribution to journalArticle

  23. Spatiotemporal pattern of Wnt-canonical pathway in dorsal telencephalic organoids.

    Ana Gonzalez Ramos, Jonothon Marshall & John O. Mason, 2018 Jul 6, (Unpublished).

    Research output: Contribution to conferencePoster

  24. Bridging the gap in translational epilepsy research - A patient brain tissue platform for validating animal data

    Jenny Wickham, 2018, Lund: Lund University: Faculty of Medicine. 79 p.

    Research output: ThesisDoctoral Thesis (compilation)

  25. Immune responses and synaptic protein expression in epilepsy

    Una Avdic, 2018, Lund: Lund University: Faculty of Medicine. 103 p.

    Research output: ThesisDoctoral Thesis (compilation)

  26. Nonconvulsive status epilepticus in rats leads to brain pathology

    Una Avdic, Matilda Ahl, Deepti Chugh, Idrish Ali, Karthik Chary, Alejandra Sierra & Christine T. Ekdahl, 2018, In : Epilepsia. 59, 5, p. 945-958

    Research output: Contribution to journalArticle

  27. 2017
  28. Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

    Natalia Avaliani, Ulrich Pfisterer, Andreas Heuer, Malin Parmar, Merab Kokaia & My Andersson, 2017 Nov 26, In : Stem Cells International. 2017, 9 p., 5718608.

    Research output: Contribution to journalArticle

  29. Altered chloride homeostasis decreases the action potential threshold and increases hyperexcitability in hippocampal neurons

    Andreas T. Sørensen, Marco Ledri, Miriam Melis, Litsa Nikitidou Ledri, My Andersson & Merab Kokaia, 2017 Nov 1, In : eNeuro. 4, 6, e0172-17.2017.

    Research output: Contribution to journalArticle

  30. Epilepsy and optogenetics: Can seizures be controlled by light?

    Jan Tönnesen & Merab Kokaia, 2017 Jul 15, In : Clinical Science. 131, 14, p. 1605-1616 12 p.

    Research output: Contribution to journalReview article

  31. Autoimmunity and mental health in William’s syndrome

    Tania Ramos-Moreno, 2017 Jan 1, Advances in Health and Disease. Lowell, D. (ed.). Nova Science Publishers, Inc., Vol. 2. p. 81-114 34 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  32. Common data elements and data management: Remedy to cure underpowered preclinical studies

    Niina Lapinlampi, Esbjörn Melin, Eleonora Aronica, Jens P. Bankstahl, Albert Becker, Cristophe Bernard, Jan A. Gorter, Olli Gröhn, Anu Lipsanen, Katarzyna Lukasiuk, Wolfgang Löscher, Jussi Paananen, Teresa Ravizza, Paolo Roncon, Michele Simonato, Annamaria Vezzani, Merab Kokaia & Asla Pitkänen, 2017 Jan 1, In : Epilepsy Research. 129, p. 87-90 4 p.

    Research output: Contribution to journalArticle

  33. Impact of generic substitution on levetiracetam serum concentration - a prospective study in an outpatient setting

    Patrik Olsson, Arne Reimers, Johanna Nilsson, Elin Hoff, Anders Lundgren, MARIA COMPAGNO STRANDBERG, Margareta Reis & Kristina Kallen, 2017.

    Research output: Contribution to conferenceAbstract

  34. Toward an Optogenetic Therapy for Epilepsy

    Jan Tönnesen, Marco Ledri & Merab Kokaia, 2017, Optogenetics: From Neuronal Function to Mapping and Disease Biology. Appasani, K. (ed.). Cambridge: Cambridge University Press, p. 292-307

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  35. Verbal memory decline from hippocampal depth electrodes in temporal lobe surgery for epilepsy

    Hanna Ljung, Arto Nordlund, MARIA STRANDBERG, Johan Bengzon & Kristina Källén, 2017, In : Epilepsia. 58, 12, p. 2143-2152

    Research output: Contribution to journalArticle

  36. 2016
  37. DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue

    N. Avaliani, M. Andersson, A. H. Runegaard, D. Woldbye & M. Kokaia, 2016 Oct 1, In : Gene Therapy. 23, 10, p. 760-766 7 p.

    Research output: Contribution to journalArticle

  38. Advances in the development of biomarkers for epilepsy

    Asla Pitkänen, Wolfgang Löscher, Annamaria Vezzani, Albert J. Becker, Michele Simonato, Katarzyna Lukasiuk, Olli Gröhn, Jens P. Bankstahl, Alon Friedman, Eleonora Aronica, Jan A. Gorter, Teresa Ravizza, Sanjay M. Sisodiya, Merab Kokaia & Heinz Beck, 2016 Jul 1, In : Lancet Neurology. 15, 8, p. 843-856 14 p.

    Research output: Contribution to journalReview article

  39. Immune response in the eye following epileptic seizures

    Matilda Ahl, Una Avdic, Cecilia Skoug, Idrish Ali, Deepti Chugh, Ulrica Englund Johansson & Christine Ekdahl Clementson, 2016 Jun 27, In : Journal of Neuroinflammation. 13, 1, 155.

    Research output: Contribution to journalArticle

  40. Optogenetic control of human neurons in organotypic brain cultures

    My Andersson, Natalia Avaliani, Andreas Svensson, Jenny Wickham, Lars H. Pinborg, Bo Jespersen, Søren H. Christiansen, Johan Bengzon, David P D Woldbye & Merab Kokaia, 2016 Apr 21, In : Scientific Reports. 6, 24818.

    Research output: Contribution to journalArticle

  41. Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry

    Fredrik Berglind, 2016, Experimental Epilepsy Group. 71 p.

    Research output: ThesisDoctoral Thesis (compilation)

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