MultiPark: Multidisciplinary research focused on Parkinson´s disease

Organisational unit: Strategic research area

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  1. 2019
  2. Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes

    Limbocker, R., Chia, S., Ruggeri, F. S., Perni, M., Cascella, R., Heller, G. T., Meisl, G., Mannini, B., Habchi, J., Michaels, T. C. T., Challa, P. K., Ahn, M., Casford, S. T., Fernando, N., Xu, C. K., Kloss, N. D., Cohen, S. I. A., Kumita, J. R., Cecchi, C., Zasloff, M. & 5 othersSara Linse, Knowles, T. P. J., Chiti, F., Vendruscolo, M. & Dobson, C. M., 2019 Dec 1, In : Nature Communications. 10, 1, 225.

    Research output: Contribution to journalArticle

  3. Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

    Alzheimer's Disease Neuroimaging Initiative, AIBL Research Group, Vermunt, L., Åsa Wallin & Visser, P-J., 2019 Jun 1, In : Alzheimer's and Dementia.

    Research output: Contribution to journalArticle

  4. Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrest

    Grand, J., Kjaergaard, J., Niklas Nielsen, Hans Friberg, Tobias Cronberg, Bro-Jeppesen, J., Karsdal, M. A., Nielsen, H. B., Frydland, M., Henriksen, K., Niklas Mattsson, Zetterberg, H. & Hassager, C., 2019 May 31, In : Biomarkers.

    Research output: Contribution to journalArticle

  5. Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia

    Meeter, L. H. H., Steketee, R. M. E., Salkovic, D., Vos, M. E., Grossman, M., McMillan, C. T., Irwin, D. J., Boxer, A. L., Rojas, J. C., Olney, N. T., Karydas, A., Miller, B. L., Pijnenburg, Y. A. L., Barkhof, F., Sánchez-Valle, R., Lladó, A., Borrego-Ecija, S., Diehl-Schmid, J., Grimmer, T., Goldhardt, O. & 27 othersAlexander F. Santillo, Oskar Hansson, Susanne Vestberg, Borroni, B., Padovani, A., Galimberti, D., Scarpini, E., Rohrer, J. D., Woollacott, I. O. C., Synofzik, M., Wilke, C., De Mendonca, A., Vandenberghe, R., Benussi, L., Ghidoni, R., Binetti, G., Niessen, W. J., Papma, J. M., Seelaar, H., Jiskoot, L. C., De Jong, F. J., Donker Kaat, L., Del Campo, M., Teunissen, C. E., Bron, E. E., Van Den Berg, E. & Van Swieten, J. C., 2019 May 28, In : Journal of Neurology, Neurosurgery and Psychiatry. 8 p.

    Research output: Contribution to journalArticle

  6. Elecsys® Total-Tau and Phospho-Tau (181P) CSF assays: Analytical performance of the novel, fully automated immunoassays for quantification of tau proteins in human cerebrospinal fluid

    Lifke, V., Kollmorgen, G., Manuilova, E., Oelschlaegel, T., Hillringhaus, L., Widmann, M., von Arnim, C. A. F., Otto, M., Christenson, R. H., Powers, J. L., Shaw, L. M., Oskar Hansson, Doecke, J. D., Li, Q. X., Teunissen, C., Tumani, H. & Blennow, K., 2019 May 23, In : Clinical Biochemistry.

    Research output: Contribution to journalArticle

  7. Method comparison study of the Elecsys® β-Amyloid (1–42) CSF assay versus comparator assays and LC-MS/MS

    Shaw, L. M., Oskar Hansson, Manuilova, E., Masters, C. L., Doecke, J. D., Li, Q. X., Rutz, S., Widmann, M., Leinenbach, A. & Blennow, K., 2019 May 23, In : Clinical Biochemistry.

    Research output: Contribution to journalArticle

  8. GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

    Rongve, A., Witoelar, A., Ruiz, A., Athanasiu, L., Abdelnour, C., Clarimon, J., Heilmann-Heimbach, S., Hernández, I., Moreno-Grau, S., de Rojas, I., Morenas-Rodríguez, E., Fladby, T., Sando, S. B., Bråthen, G., Blanc, F., Bousiges, O., Lemstra, A. W., van Steenoven, I., Londos, E., Almdahl, I. S. & 20 othersPålhaugen, L., Eriksen, J. A., Djurovic, S., Stordal, E., Saltvedt, I., Ulstein, I. D., Bettella, F., Desikan, R. S., Idland, A. V., Toft, M., Pihlstrøm, L., Snaedal, J., Tárraga, L., Boada, M., Lleó, A., Stefánsson, H., Stefánsson, K., Ramírez, A., Aarsland, D. & Andreassen, O. A., 2019 May 7, In : Scientific Reports. 9, 1, 7013.

    Research output: Contribution to journalArticle

  9. Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease

    Oskar Hansson, Lehmann, S., Otto, M., Zetterberg, H. & Lewczuk, P., 2019 Apr 22, In : Alzheimer's Research and Therapy. 11, 1, p. 1-15 15 p.

    Research output: Contribution to journalReview article

  10. Association between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients with Alzheimer Disease

    Niklas Mattsson, Cullen, N. C., Andreasson, U., Zetterberg, H. & Blennow, K., 2019 Apr 22, In : JAMA Neurology.

    Research output: Contribution to journalArticle

  11. Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

    Boza-Serrano, A., Ruiz, R., Sanchez-Varo, R., García-Revilla, J., Yang, Y., Jimenez-Ferrer, I., Paulus, A., Wennström, M., Vilalta, A., Allendorf, D., Davila, J. C., Stegmayr, J., Jiménez, S., Roca-Ceballos, M. A., Navarro-Garrido, V., Swanberg, M., Hsieh, C. L., Real, L. M., Englund, E., Linse, S. & 7 othersHakon Leffler, Ulf J. Nilsson, Brown, G. C., Gutierrez, A., Vitorica, J., Venero, J. L. & Tomas Deierborg, 2019 Apr 20, In : Acta Neuropathologica.

    Research output: Contribution to journalArticle

  12. Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism

    Sjöström, H., Yulia Surova, Markus Nilsson, Granberg, T., Westman, E., Danielle van Westen, Svenningsson, P. & Oskar Hansson, 2019 Apr 15, In : Scientific Reports. 9, 1, 6079.

    Research output: Contribution to journalArticle

  13. Relocation of coflowing immiscible liquids under acoustic field in a microchannel

    Hemachandran, E., Karthick, S., T. Laurell & Sen, A. K., 2019 Apr 15, In : EPL. 125, 5, 54002.

    Research output: Contribution to journalArticle

  14. 18 F-Flortaucipir in TDP-43 associated frontotemporal dementia

    R. Smith, A. F. Santillo, M. Landqvist Waldö, O. Strandberg, D. Berron, S. Vestberg, D. van Westen, van Swieten, J., Honer, M. & O. Hansson, 2019 Apr 15, In : Scientific Reports. 9, 1, 6082.

    Research output: Contribution to journalArticle

  15. Incidence of sports-related injuries and illnesses in paralympic athletes: a prospective study during 52 weeks

    Kristina Fagher, Dahlström, Ö., Jacobsson, J., Timpka, T. & Jan Lexell, 2019 Apr, In : British journal of sports medicine. 53, Suppl 1, p. A10 1 p., 27.

    Research output: Contribution to journalPublished meeting abstract

  16. Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia

    Nielsen, T. R., Segers, K., Vanderaspoilden, V., Beinhoff, U., Lennart Minthon, Pissiota, A., Bekkhus-Wetterberg, P., Bjørkløf, G. H., Tsolaki, M., Gkioka, M. & Waldemar, G., 2019 Mar 22, In : International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticle

  17. Differences in neurosurgical treatment of intracerebral haemorrhage: a nation-wide observational study of 578 consecutive patients

    Fahlström, A., Tobieson, L., Henrietta Nittby Redebrandt, Zeberg, H., Bartek, J., Bartley, A., Erkki, M., Hessington, A., Ebba Troberg, Mirza, S., Tsitsopoulos, P. P. & Niklas Marklund, 2019 Mar 15, In : Acta Neurochirurgica.

    Research output: Contribution to journalArticle

  18. Bättre behandlad Alzheimers sjukdom kan öka tiden att bo hemma

    Carina Wattmo, 2019 Mar 8, Neurologi i Sverige, 1, 19, p. 48-53.

    Research output: Contribution to specialist publication or newspaperSpecialist publication article

  19. Best zero level for external ICP transducer

    Peter Reinstrup, Mårten Unnerbäck, Niklas Marklund, Schalen, W., Arrocha, J. C., Bloomfield, E. L., Sadegh, V. & Hesselgard, K., 2019 Mar 8, In : Acta Neurochirurgica.

    Research output: Contribution to journalArticle

  20. A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli

    Kalyani Sanagavarapu, Nüske, E., Nasir, I., Meisl, G., Jasper N. Immink, Sormanni, P., Vendruscolo, M., Knowles, T. P. J., Malmendal, A., Cabaleiro-Lago, C. & Sara Linse, 2019 Mar 6, In : Scientific Reports. 9, 1, 3680.

    Research output: Contribution to journalArticle

  21. Dynamic protein changes in the perihaemorrhagic zone of Surgically Treated Intracerebral Haemorrhage Patients

    Tobieson, L., Ghafouri, B., Zsigmond, P., Rossitti, S., Hillman, J. & Niklas Marklund, 2019 Feb 28, In : Scientific Reports. 9, 1, 3181.

    Research output: Contribution to journalArticle

  22. Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau protein

    Zettergren, A., Höglund, K., Kern, S., Thorvaldsson, V., Johan Skoog, M., Oskar Hansson, Andreasen, N., Bogdanovic, N., Blennow, K., Skoog, I. & Zetterberg, H., 2019 Feb 21, In : Scientific Reports. 9, 1, 2460.

    Research output: Contribution to journalArticle

  23. The European Journal of Ageing and the memorable year 2018

    Aartsen, M. J., Kliegel, M., Wahrendorf, M., Minicuci, N. & Susanne Iwarsson, 2019 Feb 18, In : European Journal of Ageing.

    Research output: Contribution to journalDebate/Note/Editorial

  24. A walk through tau therapeutic strategies

    Jadhav, S., Avila, J., Michael Schöll, Kovacs, G. G., Kövari, E., Skrabana, R., Evans, L. D., Kontsekova, E., Malawska, B., de Silva, R., Buee, L. & Zilka, N., 2019 Feb 15, In : Acta neuropathologica communications. 7, 1, 1 p.

    Research output: Contribution to journalReview article

  25. Pridopidine Induces Functional Neurorestoration Via the Sigma-1 Receptor in a Mouse Model of Parkinson’s Disease

    Veronica Francardo, Geva, M., Bez, F., Denis, Q., Steiner, L., Hayden, M. R. & M. Angela Cenci, 2019 Feb 12, In : Neurotherapeutics.

    Research output: Contribution to journalArticle

  26. EuroInf 2: Subthalamic stimulation, apomorphine, and levodopa infusion in Parkinson's disease

    EUROPAR, Dafsari, H. S., Martinez-Martin, P., Rizos, A., Trost, M., dos Santos Ghilardi, M. G., Reddy, P., Sauerbier, A., Petry-Schmelzer, J. N., Kramberger, M., Borgemeester, R. W. K., Barbe, M. T., Ashkan, K., Silverdale, M., Evans, J., Odin, P., Fonoff, E. T., Fink, G. R., Henriksen, T., Ebersbach, G. & 5 othersPirtošek, Z., Visser-Vandewalle, V., Antonini, A., Timmermann, L. & Ray Chaudhuri, K., 2019 Feb 4, In : Movement Disorders.

    Research output: Contribution to journalArticle

  27. Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

    Tiklová, K., Björklund, Å. K., Lahti, L., Alessandro Fiorenzano, Sara Nolbrant, Gillberg, L., Volakakis, N., Yokota, C., Hilscher, M. M., Hauling, T., Holmström, F., Joodmardi, E., Nilsson, M., Malin Parmar & Perlmann, T., 2019 Feb 4, In : Nature Communications. 10, 1, 581.

    Research output: Contribution to journalArticle

  28. Data-driven approaches for tau-PET imaging biomarkers in Alzheimer's disease

    The Alzheimer's Disease Neuroimaging Initiative, The Swedish BioFINDER study, Vogel, J. W., Niklas Mattsson, Iturria-Medina, Y., Olof T. Strandberg, Michael Schöll, Dansereau, C., Villeneuve, S., van der Flier, W. M., Scheltens, P., Bellec, P., Evans, A. C., Oskar Hansson & Rik Ossenkoppele, 2019 Feb 1, In : Human Brain Mapping. 40, 2, p. 638-651

    Research output: Contribution to journalArticle

  29. Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice

    Xu, S. F., Zhang, Y. H., Wang, S., Pang, Z. Q., Fan, Y. G., Jia Yi Li, Wang, Z. Y. & Guo, C., 2019 Feb 1, In : Redox Biology. 21, 101090.

    Research output: Contribution to journalArticle

  30. Brain myoinositol as a potential marker of amyloid-related pathology: A longitudinal study

    Voevodskaya, O., Poulakis, K., Pia Sundgren, Danielle Van Westen, Sebastian Palmqvist, Wahlund, L. O., Erik Stomrud, Oskar Hansson & Westman, E., 2019 Jan 29, In : Neurology. 92, 5, p. E395-E405

    Research output: Contribution to journalArticle

  31. Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients: an explorative analysis of a randomized trial

    Ebner, F., Ullén, S., Åneman, A., Tobias Cronberg, Niklas Mattsson, Hans Friberg, Hassager, C., Kjærgaard, J., Kuiper, M., Pelosi, P., Johan Undén, Wise, M. P., Wetterslev, J. & Niklas Nielsen, 2019 Jan 28, In : Critical care (London, England). 23, 1, 1 p.

    Research output: Contribution to journalArticle

  32. Cells in Culture, Cells in Suspense: Practices of Cultural Production in Foetal Cell Research

    Andréa Wiszmeg, 2019 Jan 18, Lund: Department of Arts and Cultural Sciences, Lund University. 210 p.

    Research output: ThesisDoctoral Thesis (compilation)

  33. Isolation of a Low Number of Sperm Cells from Female DNA in a Glass-PDMS-Glass Microchip via Bead-Assisted Acoustic Differential Extraction

    Xu, K., Clark, C. P., Poe, B. L., Lounsbury, J. A., Johan Nilsson, Thomas Laurell & Landers, J. P., 2019 Jan 17, In : Analytical Chemistry.

    Research output: Contribution to journalArticle

  34. Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration

    Ashton, N. J., Leuzy, A., Lim, Y. M., Troakes, C., Hortobágyi, T., Höglund, K., Aarsland, D., Lovestone, S., Michael Schöll, Blennow, K., Zetterberg, H. & Hye, A., 2019 Jan 9, In : Acta neuropathologica communications. 7, 1, 5.

    Research output: Contribution to journalArticle

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