MultiPark: Multidisciplinary research focused on Parkinson´s disease

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  1. Amyloid biomarkers in Alzheimer's disease.

    Blennow, K., Niklas Mattsson, Schöll, M., Oskar Hansson & Zetterberg, H., 2015, In : Trends in Pharmacological Sciences. 36, 5, p. 297-309

    Research output: Contribution to journalReview article

  2. Amyloid blood biomarker detects Alzheimer's disease

    Nabers, A., Perna, L., Lange, J., Mons, U., Schartner, J., Güldenhaupt, J., Saum, K. U., Shorena Janelidze, Holleczek, B., Rujescu, D., Oskar Hansson, Gerwert, K. & Brenner, H., 2018, In : EMBO Molecular Medicine. 10, 5, e8763.

    Research output: Contribution to journalArticle

  3. Amyloid network topology characterizes the progression of Alzheimer's disease during the predementia stages

    Pereira, J. B., Strandberg, T. O., Sebastian Palmqvist, Volpe, G., Danielle Van Westen, Westman, E. & Oskar Hansson, 2018 Jan 1, In : Cerebral Cortex. 28, 1, p. 340-349 10 p.

    Research output: Contribution to journalArticle

  4. Amyloid pathology in the progression to mild cognitive impairment

    Philip S. Insel, Oskar Hansson, Mackin, R. S., Weiner, M., Niklas Mattsson & Alzheimer's Disease Neuroimaging Initiative, 2018 Apr, In : Neurobiology of Aging. 64, p. 76-84 9 p.

    Research output: Contribution to journalArticle

  5. Amyloid PET and cognitive decline in cognitively normal individuals: the SCIENCe project

    Timmers, T., Rik Ossenkoppele, Verfaillie, S. C. J., van der Weijden, C. W. J., Slot, R. E. R., Wesselman, L. M. P., Windhorst, A. D., Wolters, E. E., Yaqub, M., Prins, N. D., Lammertsma, A. A., Scheltens, P., van der Flier, W. M. & van Berckel, B. N. M., 2019, In : Neurobiology of Aging. 79, p. 50-58 9 p.

    Research output: Contribution to journalArticle

  6. An African-American family with dystonia.

    Andreas Puschmann, Xiao, J., Bastian, R. W., Searcy, J. A., Ledoux, M. S. & Wszolek, Z. K., 2011, In : Parkinsonism & Related Disorders. 17, p. 547-550

    Research output: Contribution to journalArticle

  7. Analysis of Alpha-Synuclein in Malignant Melanoma - Development of a SRM Quantification Assay.

    Charlotte Welinder, Göran B Jönsson, Christian Ingvar, Lundgren, L., Bo Baldetorp, Håkan Olsson, Breslin, T., Rezeli, M., Bo Jansson, Fehniger, T. E., Thomas Laurell, Elisabet Wieslander, Krzysztof Pawlowski & Marko-Varga, G., 2014, In : PLoS ONE. 9, 10, e110804.

    Research output: Contribution to journalArticle

  8. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies

    Kun-Rodrigues, C., Ross, O. A., Orme, T., Shepherd, C., Parkkinen, L., Darwent, L., Hernandez, D., Ansorge, O., Clark, L. N., Honig, L. S., Marder, K., Lemstra, A., Scheltens, P., van der Flier, W., Louwersheimer, E., Holstege, H., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H. & 44 others, Barber, I., Braae, A., Brown, K., Morgan, K., Maetzler, W., Berg, D., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Trojanowski, J. Q., Serrano, G. E., Beach, T. G., Clarimon, J., Lleó, A., Morenas-Rodríguez, E., Lesage, S., Galasko, D., Masliah, E., Santana, I., Diez, M., Pastor, P., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Stone, D. J., Pickering-Brown, S., Mann, D., Dickson, D. W., Halliday, G. M., Singleton, A., Guerreiro, R. & Bras, J., 2017 Jan, In : Neurobiology of Aging. 49, 214.e13-214.e15.

    Research output: Contribution to journalArticle

  9. Analysis of the length distribution of amyloid fibrils by centrifugal sedimentation

    Arosio, P., Tommy Cedervall, Knowles, T. P. J. & Sara Linse, 2016 Jul 1, In : Analytical Biochemistry. 504, p. 7-13 7 p.

    Research output: Contribution to journalArticle

  10. Analysis of vesicular trafficking in primary neurons by live imaging.

    Tampellini, D. & Gunnar Gouras, 2011, In : Methods in Molecular Biology. 793, p. 343-350

    Research output: Contribution to journalArticle

  11. Analysis of White Adipose Tissue Gene Expression Reveals CREB1 Pathway Altered in Huntington's Disease.

    McCourt, A., Parker, J., Silajdzic, E., Haider, S., Sethi, H., Tabrizi, S. J., Warner, T. T. & Maria Björkqvist, 2015, In : Journal of Huntington's disease. 4, 4, p. 371-382

    Research output: Contribution to journalArticle

  12. An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.

    Habchi, J., Arosio, P., Perni, M., Costa, A. R., Yagi-Utsumi, M., Joshi, P., Chia, S., Cohen, S. I. A., Müller, M. B. D., Sara Linse, Nollen, E. A. A., Dobson, C. M., Knowles, T. P. J. & Vendruscolo, M., 2016, In : Science Advances. 2, 2, e1501244.

    Research output: Contribution to journalArticle

  13. An enzyme activity as a potential biomarker for Alzheimer's disease.

    Andreasson, U., Bjerke, M., Gobom, J., Oskar Hansson, Per Johansson, Svensson, J., Zetterberg, H. & Blennow, K., 2010, In : Alzheimer's & Dementia. 6, 4, p. S497–S498

    Research output: Contribution to journalPublished meeting abstract

  14. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

    Martin Wahlestedt, Norddahl, G., Sten, G., Amol Ugale, Micha Frisk, M-A., Mattsson, R., Tomas Deierborg, Mikael Sigvardsson & David Bryder, 2013, In : Blood. 121, 21, p. 4257-4264

    Research output: Contribution to journalArticle

  15. A new approach for ratiometric in vivo calcium imaging of microglia

    Brawek, B., Liang, Y., Savitska, D., Li, K., Fomin-Thunemann, N., Kovalchuk, Y., Zirdum, E., Johan Jakobsson & Garaschuk, O., 2017 Dec 1, In : Scientific Reports. 7, 1, 6030.

    Research output: Contribution to journalArticle

  16. A new automated method for analysis of rCBF-SPECT images based on the active-shape algorithm: normal values.

    Douglas Hägerström, Jakobsson, D., Erik Stomrud, Andersson, A-M., Ryding, E., Elisabet Londos, Lennart Minthon, Ingmar Rosén & Edenbrandt, L., 2012, In : Clinical Physiology and Functional Imaging. 32, 2, p. 114-119

    Research output: Contribution to journalArticle

  17. A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

    Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Oskar Hansson, Nordberg, A., Jacobs, A. H. & IMBI Project, 2019, In : Alzheimer's and Dementia. 15, 8, p. 1081-1103

    Research output: Contribution to journalArticle

  18. An ex Vivo Model for Evaluating Blood-Brain Barrier Permeability, Efflux, and Drug Metabolism.

    Karin Hellman, Aadal Nielsen, P., Fredrik Ek & Roger Olsson, 2016, In : ACS Chemical Neuroscience. 7, 5, p. 668-680 13 p.

    Research output: Contribution to journalArticle

  19. Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?

    Niklas Marklund & Hillered, L., 2011 Oct, In : British Journal of Pharmacology. 164, 4, p. 1207-29

    Research output: Contribution to journalReview article

  20. Animal models of l-DOPA-induced dyskinesia: the 6-OHDA-lesioned rat and mouse

    Tronci, E. & Veronica Francardo, 2018, In : Journal of Neural Transmission. 125, 8, p. 1137-1144

    Research output: Contribution to journalArticle

  21. Animal models of l-DOPA-induced dyskinesia: an update on the current options.

    Iderberg, H., Veronica Francardo & Pioli, E. Y., 2012, In : Neuroscience. 211, p. 13-27

    Research output: Contribution to journalArticle

  22. Animal models of l-dopa-induced dyskinesia in Parkinson's disease

    M. Angela Cenci & Crossman, A. R., 2018 Jun 1, In : Movement Disorders. 33, 6, p. 889-899

    Research output: Contribution to journalReview article

  23. Animal Models of Parkinson’s Disease

    Maria Swanberg & Konnova, E. A., 2018 Dec 21, Parkinson's Disease: Pathogenesis and Clinical Aspects. Stoker, T. B. & Greenland, J. C. (eds.). Brisbane (AU): Codon Publications, p. 83-106

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  24. Animal Models of Parkinson's Disease: Limits and Relevance to Neuroprotection Studies

    Bezard, E., Yue, Z., Deniz Kirik & Spillantini, M. G., 2013, In : Movement Disorders. 28, 1, p. 61-70

    Research output: Contribution to journalReview article

  25. An integrated acousto- and dielectrophoresis device for tumor cell separation, concentration, and single-cell trapping

    M. Antfolk, Kim, S. H., Saori, K., Kaneda, S., Fujii, T. & T. Laurell, 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 1657-1658 2 p.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  26. An Integrated Workflow for Multiplex CSF Proteomics and Peptidomics-Identification of Candidate Cerebrospinal Fluid Biomarkers of Alzheimer's Disease

    Holtta, M., Lennart Minthon, Oskar Hansson, Holmen-Larsson, J., Pike, I., Ward, M., Kuhn, K., Ruetschi, U., Zetterberg, H., Blennow, K. & Gobom, J., 2015, In : Journal of Proteome Research. 14, 2, p. 654-663

    Research output: Contribution to journalArticle

  27. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

    Tordo, J., O'Leary, C., Antunes, A. S. L. M., Palomar, N., Aldrin-Kirk, P., Basche, M., Bennett, A., D'Souza, Z., Gleitz, H., Godwin, A., Holley, R. J., Parker, H., Liao, A. Y., Rouse, P., Youshani, A. S., Dridi, L., Martins, C., Levade, T., Stacey, K. B., Davis, D. M. & 11 others, Dyer, A., Clément, N., Tomas Björklund, Ali, R. R., Agbandje-McKenna, M., Rahim, A. A., Pshezhetsky, A., Waddington, S. N., Linden, R. M., Bigger, B. W. & Henckaerts, E., 2018 Jul 1, In : Brain. 141, 7, p. 2014-2031 18 p.

    Research output: Contribution to journalArticle

  28. A novel approach to investigating propagation patterns in endocardial atrial fibrillation signals

    Richter, U., Faes, L., Cristoforetti, A., Masè, M., Ravelli, F., Martin Stridh & Leif Sörnmo, 2011, In : Journal of Electrocardiology. 44, 2, p. e27

    Research output: Contribution to journalPublished meeting abstract

  29. A novel ARC gene polymorphism is associated with reduced risk of Alzheimer's disease

    Landgren, S., von Otter, M., Palmer, M. S., Zetterstrom, C., Nilsson, S., Skoog, I., Gustafson, D. R., Lennart Minthon, Wallin, A., Andreasen, N., Bogdanovic, N., Marcusson, J., Blennow, K., Zetterberg, H. & Kettunen, P., 2012, In : Journal of Neural Transmission. 119, 7, p. 833-842

    Research output: Contribution to journalArticle

  30. A Novel Blood Test for the Early Detection of Alzheimer's Disease

    Rye, P. D., Booij, B. B., Grave, G., Lindahl, T., Kristiansen, L., Andersen, H-M., Horndalsveen, P. O., Nygaard, H. A., Naik, M., Hoprekstad, D., Wetterberg, P., Nilsson, C., Aarsland, D., Sharma, P. & Lonneborg, A., 2011, In : Journal of Alzheimer's Disease. 23, 1, p. 121-129

    Research output: Contribution to journalArticle

  31. A novel combinational approach of microstimulation and bioluminescence imaging to study the mechanisms of action of cerebral electrical stimulation in mice

    Arsenault, D., Drouin-Ouellet, J., Saint-Pierre, M., Petrou, P., Dubois, M., Kriz, J., Barker, R. A., Cicchetti, A. & Cicchetti, F., 2015 May 15, In : Journal of Physiology. 593, 10, p. 2257-78 22 p.

    Research output: Contribution to journalArticle

  32. A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein

    Landeck, N., Hall, H., Ardah, M. T., Majbour, N. K., El-Agnaf, O. M. A., Halliday, G. & Deniz Kirik, 2016 Aug 22, In : Molecular Neurodegeneration. 11, 1, 125.

    Research output: Contribution to journalArticle

  33. A novel partial volume correction method for accurate quantification of [18F] flortaucipir in the hippocampus

    Wolters, E. E., Golla, S. S. V., Timmers, T., Rik Ossenkoppele, van der Weijden, C. W. J., Scheltens, P., Schwarte, L., Schuit, R. C., Windhorst, A. D., Barkhof, F., Yaqub, M., Lammertsma, A. A., Boellaard, R. & van Berckel, B. N. M., 2018, In : EJNMMI Research. 8, 79.

    Research output: Contribution to journalArticle

  34. A novel process of viral vector barcoding and library preparation enables high-diversity library generation and recombination-free paired-end sequencing

    Marcus Davidsson, Diaz-Fernandez, P., Schwich, O. D., Torroba, M., Wang, G. & Tomas Björklund, 2016 Nov 22, In : Scientific Reports. 6, 37563.

    Research output: Contribution to journalArticle

  35. A novel quantification-driven proteomic strategy identifies an endogenous peptide of pleiotrophin as a new biomarker of Alzheimer's disease

    Skillbäck, T., Niklas Mattsson, Hansson, K. F., Mirgorodskaya, E., Dahlén, R., van der Flier, W., Scheltens, P., Duits, F., Oskar Hansson, Teunissen, C., Blennow, K., Zetterberg, H. & Gobom, J., 2017 Dec 1, In : Scientific Reports. 7, 1, 13333.

    Research output: Contribution to journalArticle

  36. A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.

    Christian Hansen, Tomas Björklund, Petit, G., Lundblad, M., Murmu, R., Brundin, P. & Jia-Yi Li, 2013, In : Neurobiology of Disease. 56C, April,30, p. 145-155

    Research output: Contribution to journalArticle

  37. Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA)

    Herva, M. E., Zibaee, S., Fraser, G., Barker, R. A., Goedert, M. & Spillantini, M. G., 2014 Apr 25, In : Journal of Biological Chemistry. 289, 17, p. 11897-905 9 p.

    Research output: Contribution to journalArticle

  38. Antibodies against phosphorylcholine are not altered in plasma of patients with Alzheimer's disease

    Silajdzic, E., Maria Björkqvist & Oskar Hansson, 2015, In : BMC Neurology. 15, 8.

    Research output: Contribution to journalReview article

  39. Antidopaminergic Medication is Associated with More Rapidly Progressive Huntington's Disease

    Tedroff, J., Waters, S., Barker, R. A., Roos, R., Squitieri, F. & EHDN Registry Study Group, 2015, In : Journal of Huntington's disease. 4, 2, p. 131-40 10 p.

    Research output: Contribution to journalArticle

  40. Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

    Bezard, E., Munoz, A., Tronci, E., Pioli, E. Y., Li, Q., Porras, G., Anders Björklund & Carta, M., 2013, In : Neuroscience Research. 77, 4, p. 242-246

    Research output: Contribution to journalArticle

  41. Antihypertensive Therapy Is Associated with Reduced Rate of Conversion to Alzheimer's Disease in Midregional Proatrial Natriuretic Peptide Stratified Subjects with Mild Cognitive Impairment

    Schneider, P., Buerger, K., Teipel, S., Uspenskaya, O., Hartmann, O., Oskar Hansson, Lennart Minthon, Rujescu, D., Moeller, H., Zetterberg, H., Blennow, K., Ernst, A., Bergmann, A. & Hampel, H., 2011, In : Biological Psychiatry. 70, 2, p. 145-151

    Research output: Contribution to journalArticle

  42. Antipsychotic Treatment Associated With Increased Mortality Risk in Patients With Dementia. A Registry-Based Observational Cohort Study

    Schwertner, E., Secnik, J., Garcia-Ptacek, S., Johansson, B., Katarina Nagga, Eriksdotter, M., Winblad, B. & Religa, D., 2019, In : Journal of the American Medical Directors Association. 20, 3, p. 323-329.e2

    Research output: Contribution to journalArticle

  43. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease

    Villaescusa, J. C., Li, B., Toledo, E. M., Rivetti di Val Cervo, P., Yang, S., Stott, S. R., Kaiser, K., Islam, S., Gyllborg, D., Laguna-Goya, R., Landreh, M., Lönnerberg, P., Falk, A., Bergman, T., Barker, R. A., Linnarsson, S., Selleri, L. & Arenas, E., 2016 Sep 15, In : EMBO Journal. 35, 18, p. 1963-78 16 p.

    Research output: Contribution to journalArticle

  44. A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia

    Siva, K., Fredrik Ek, Jun Chen, Abdul Ghani Alattar, Sigmundsson, K., Roger Olsson, Wlodarski, M., Lundbäck, T. & Johan Flygare, 2019, In : SLAS discovery : advancing life sciences R & D. 24, 3, p. 304-313 10 p.

    Research output: Contribution to journalArticle

  45. A Pilot Study Examining Associations between DYRK1A and alpha-Synuclein Dementias

    Jones, E. L., Aarsland, D., Elisabet Londos & Ballard, C., 2012, In : Neurodegenerative Diseases. 10, 1-4, p. 229-231

    Research output: Contribution to journalArticle

  46. A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons

    Braunstein, K. E., Eschbach, J., Rona-Voeroes, K., Soylu, R., Mikrouli, E., Larmet, Y., Rene, F., De Aguilar, J-L. G., Loeffler, J-P., Mueller, H-P., Bucher, S., Kaulisch, T., Niessen, H. G., Tillmanns, J., Fischer, K., Schwalenstoecker, B., Kassubek, J., Pichler, B., Stiller, D., Petersén, Å. & 2 others, Ludolph, A. C. & Dupuis, L., 2010, In : Human Molecular Genetics. 19, 22, p. 4385-4398

    Research output: Contribution to journalArticle

  47. Apolipoprotein E Genotype and the Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers for Alzheimer Disease.

    Lautner, R., Sebastian Palmqvist, Mattsson, N., Andreasson, U., Wallin, A., Pålsson, E., Jakobsson, J., Herukka, S-K., Owenius, R., Olsson, B., Hampel, H., Rujescu, D., Ewers, M., Landén, M., Lennart Minthon, Blennow, K., Zetterberg, H. & Oskar Hansson, 2014, In : JAMA Psychiatry. 71, 10, p. 1183-1191

    Research output: Contribution to journalArticle

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