MultiPark: Multidisciplinary research focused on Parkinson´s disease

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  1. Article
  2. Regional structural hypo- and hyperconnectivity of frontal–striatal and frontal–thalamic pathways in behavioral variant frontotemporal dementia

    Jakabek, D., Power, B. D., Macfarlane, M. D., Walterfang, M., Velakoulis, D., Danielle van Westen, Jimmy Lätt, Markus Nilsson, Looi, J. C. L. & Alexander F. Santillo, 2018, In : Human Brain Mapping. 39, 10, p. 4083-4093 11 p.

    Research output: Contribution to journalArticle

  3. Chronic depressive symptomatology and CSF amyloid beta and tau levels in mild cognitive impairment

    The Alzheimer's Disease Neuroimaging Initiative, Gonzales, M. M., Philip S. Insel, Nelson, C., Tosun, D., Michael Schöll, Niklas Mattsson, Sacuiu, S., Bickford, D., Weiner, M. W. & Mackin, R. S., 2018, In : International Journal of Geriatric Psychiatry. 33, 10, p. 1305-1311 7 p.

    Research output: Contribution to journalArticle

  4. First comprehensive tool for screening pain in Parkinson's disease: the King's Parkinson's Disease Pain Questionnaire

    EUROPAR , MDS Non-motor PD Study Group, Martinez-Martin, P., Rizos, A. M., Wetmore, J., Antonini, A., P. Odin, Pal, S., Sophia, R., Carroll, C., Martino, D., Falup-Pecurariu, C., Kessel, B., Andrews, T., Paviour, D., Trenkwalder, C. & Chaudhuri, K. R., 2018, In : European Journal of Neurology. 25, 10, p. 1255-1261 7 p.

    Research output: Contribution to journalArticle

  5. Use of flutemetamol F18-labeled positron emission tomography and other biomarkers to assess risk of clinical progression in patients with amnestic mild cognitive impairment

    Wolk, D. A., Sadowsky, C., Safirstein, B., Rinne, J. O., Duara, R., Perry, R., Agronin, M., Gamez, J., Shi, J., Ivanoiu, A., Minthon, L., Walker, Z., Hasselbalch, S., Holmes, C., Sabbagh, M., Albert, M., Fleisher, A., Loughlin, P., Triau, E., Frey, K. & 10 othersHøgh, P., Bozoki, A., Bullock, R., Salmon, E., Farrar, G., Buckley, C. J., Zanette, M., Sherwin, P. F., Cherubini, A. & Inglis, F., 2018, In : JAMA Neurology. 75, 9, p. 1114-1123 10 p.

    Research output: Contribution to journalArticle

  6. Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain

    Luis Quintino, Namislo, A., Marcus Davidsson, Breger, L. S., Kavanagh, P., Avallone, M., Elgstrand-Wettergren, E., Isaksson, C. & Cecilia Lundberg, 2018, In : Molecular Therapy - Methods and Clinical Development. 11, p. 29-39 11 p.

    Research output: Contribution to journalArticle

  7. Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay

    Baldo, B., Sajjad, M. U., Rachel Y. Cheong, Bigarreau, J., Vijayvargia, R., McLean, C., Perrier, A. L., Seong, I. S., Halliday, G., Åsa Petersén & Deniz Kirik, 2018, In : eNeuro. 5, 4

    Research output: Contribution to journalArticle

  8. Arterial spin labeling MR imaging for differentiation between high- and low-grade glioma - A meta-analysis

    Falk Delgado, A., De Luca, F., Danielle Van Westen & Falk Delgado, A., 2018, In : Neuro-Oncology. 20, 11, p. 1450-1461 12 p.

    Research output: Contribution to journalArticle

  9. SAR by kinetics for drug discovery in protein misfolding diseases

    Chia, S., Habchi, J., Michaels, T. C. T., Cohen, S. I. A., Sara Linse, Dobson, C. M., Knowles, T. P. J. & Vendruscolo, M., 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. 10245-10250 6 p.

    Research output: Contribution to journalArticle

  10. Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs

    Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Noer, O., Nielsen, E. H. T., Schacht, A. C., Landeck, N., Deniz Kirik, Orlowski, D., Sørensen, J. C. H., Doudet, D. J. & Landau, A. M., 2018, In : Scientific Reports. 8, 1, 15715.

    Research output: Contribution to journalArticle

  11. Loss of Regulator of G-Protein Signaling 5 Leads to Neurovascular Protection in Stroke

    Özen, I., Michaela Roth, Barbariga, M., Abderahim Gaceb, Tomas Deierborg, Genové, G. & Gesine Paul, 2018, In : Stroke. 49, 9, p. 2182-2190 9 p.

    Research output: Contribution to journalArticle

  12. Clinical phenotype, atrophy, and small vessel disease in APOEε2 carriers with Alzheimer disease

    Groot, C., Sudre, C. H., Barkhof, F., Teunissen, C. E., van Berckel, B. N. M., Seo, S. W., Ourselin, S., Scheltens, P., Cardoso, M. J., van der Flier, W. M. & Rik Ossenkoppele, 2018, In : Neurology. 91, 20, p. e1851-e1859

    Research output: Contribution to journalArticle

  13. Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

    Bergeron, D., Niklas Mattsson, Nilsson, C., Oskar Hansson, Rik Ossenkoppele & et al., 2018, In : Annals of Neurology. 84, 5, p. 729-740 12 p.

    Research output: Contribution to journalArticle

  14. Effects of Urea and TMAO on Lipid Self-Assembly under Osmotic Stress Conditions

    Dat Pham, Wolde-Kidan, A., Gupta, A., Schlaich, A., Schneck, E., Netz, R. R. & Emma Sparr, 2018, In : The Journal of Physical Chemistry B. 122, 25, p. 6471-6482

    Research output: Contribution to journalArticle

  15. Solid and fluid segments within the same molecule of stratum corneum ceramide lipid

    Dat Pham, Gooris, G., Bouwstra, J. A., Emma Sparr, Daniel Topgaard & Enamul Mojumdar, 2018, In : Quarterly Reviews of Biophysics. 51, e7, 9 p.

    Research output: Contribution to journalArticle

  16. Genetic characterization of amyloid-β and tau network spread

    Rik Ossenkoppele & Oskar Hansson, 2018, In : Nature Medicine. 24, p. 1790–1792

    Research output: Contribution to journalArticle

  17. Will FTLD-tau work for all when FTDP-17 retires?

    Emil Ygland, Maria Landqvist Waldö, Elisabet Englund, Andreas Puschmann & Nilsson, C., 2018, In : Brain : a journal of neurology. 141, 8, p. e62

    Research output: Contribution to journalArticle

  18. Systematic evaluation of levodopa-carbidopa intestinal gel patient-responder characteristics

    Standaert, D. G., Boyd, J. T., Per Odin, Robieson, W. Z., Zamudio, J. & Chatamra, K., 2018, In : npj Parkinson's Disease. 4, p. 1-6 4.

    Research output: Contribution to journalArticle

  19. Cerebrovascular and amyloid pathology in predementia stages: The relationship with neurodegeneration and cognitive decline

    Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Åsa K. Wallin, Van Buchem, M. A., Oleksik, A., Verbeek, M. M., Olde Rikkert, M., Van Der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 2017 Dec 29, In : Alzheimer's Research and Therapy. 9, 1, 101.

    Research output: Contribution to journalArticle

  20. Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes

    Rostami, J., Holmqvist, S., Lindström, V., Sigvardson, J., Westermark, G. T., Ingelsson, M., Bergström, J., Laurent Roybon & Erlandsson, A., 2017 Dec 6, In : Journal of Neuroscience. 37, 49, p. 11835-11853 19 p.

    Research output: Contribution to journalArticle

  21. CK2 oppositely modulates L-DOPA-induced dyskinesia via striatal projection neurons expressing D1 or D2 receptors

    Cortés, M., Malave, L., Castello, J., Flajolet, M., M. Angela Cenci, Friedman, E. & Rebholz, H., 2017 Dec 6, In : Journal of Neuroscience. 37, 49, p. 11930-11946 17 p.

    Research output: Contribution to journalArticle

  22. The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation

    Aprile, F. A., Källstig, E., Limorenko, G., Vendruscolo, M., Ron, D. & Christian Hansen, 2017 Dec 1, In : Scientific Reports. 7, 1, 9039.

    Research output: Contribution to journalArticle

  23. A novel quantification-driven proteomic strategy identifies an endogenous peptide of pleiotrophin as a new biomarker of Alzheimer's disease

    Skillbäck, T., Niklas Mattsson, Hansson, K. F., Mirgorodskaya, E., Dahlén, R., van der Flier, W., Scheltens, P., Duits, F., Oskar Hansson, Teunissen, C., Blennow, K., Zetterberg, H. & Gobom, J., 2017 Dec 1, In : Scientific Reports. 7, 1, 13333.

    Research output: Contribution to journalArticle

  24. Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington's disease

    Marie Sjögren, Duarte, A. I., McCourt, A. C., Liliya Shcherbina, Nils Wierup & Maria Björkqvist, 2017 Dec 1, In : Scientific Reports. 7, 1, 13896.

    Research output: Contribution to journalArticle

  25. Neurofilament light protein in CSF and blood is associated with neurodegeneration and disease severity in Huntington's disease

    Rana Soylu-Kucharz, Sandelius, Å., Marie Sjögren, Blennow, K., Wild, E. J., Zetterberg, H. & Maria Björkqvist, 2017 Dec 1, In : Scientific Reports. 7, 1, 14114.

    Research output: Contribution to journalArticle

  26. A new approach for ratiometric in vivo calcium imaging of microglia

    Brawek, B., Liang, Y., Savitska, D., Li, K., Fomin-Thunemann, N., Kovalchuk, Y., Zirdum, E., Johan Jakobsson & Garaschuk, O., 2017 Dec 1, In : Scientific Reports. 7, 1, 6030.

    Research output: Contribution to journalArticle

  27. Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia

    Lerner, R. P., Veronica Francardo, Fujita, K., Bimpisidis, Z., Jourdain, V. A., Tang, C. C., Dewey, S. L., Chaly, T., M. Angela Cenci & Eidelberg, D., 2017 Dec 1, In : Scientific Reports. 7, 1, 16005.

    Research output: Contribution to journalArticle

  28. Translating scientific advances into disease-modifying therapies for Parkinson's Disease

    M. Angela Cenci & Olanow, C. W., 2017 Dec 1, In : Experimental Neurology. 298, p. 135-136 2 p.

    Research output: Contribution to journalArticle

  29. Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders

    Sjödin, S., Oskar Hansson, Öhrfelt, A., Brinkmalm, G., Zetterberg, H., Brinkmalm, A. & Blennow, K., 2017 Dec 1, In : Proteomics - Clinical Applications. 11, 11-12, 1700100.

    Research output: Contribution to journalArticle

  30. Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

    Avaliani, N., Pfisterer, U., Andreas Heuer, Malin Parmar, Merab Kokaia & My Andersson, 2017 Nov 26, In : Stem Cells International. 2017, 9 p., 5718608.

    Research output: Contribution to journalArticle

  31. Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury

    Wicher, G., Wallenquist, U., Lei, Y., Enoksson, M., Li, X., Fuchs, B., Abu Hamdeh, S., Niklas Marklund, Hillered, L., Nilsson, G. & Forsberg-Nilsson, K., 2017 Nov 15, In : Journal of Neurotrauma. 34, 22, p. 3173-3182

    Research output: Contribution to journalArticle

  32. Serum tau and neurological outcome in cardiac arrest

    Niklas Mattsson, Zetterberg, H., Niklas Nielsen, Blennow, K., Josef Dankiewicz, Hans Friberg, Gisela Lilja, Philip S. Insel, Rylander, C., Stammet, P., Aneman, A., Hassager, C., Kjaergaard, J., Kuiper, M., Pellis, T., Wetterslev, J., Wise, M. & Tobias Cronberg, 2017 Nov 2, In : Annals of Neurology. 82, 5, p. 665-675 11 p.

    Research output: Contribution to journalArticle

  33. CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients

    Skillbäck, T., Delsing, L., Synnergren, J., Niklas Mattsson, Shorena Janelidze, Katarina Nägga, Kilander, L., Hicks, R., Wimo, A., Winblad, B., Oskar Hansson, Blennow, K., Eriksdotter, M. & Zetterberg, H., 2017 Nov 1, In : Neurobiology of Aging. 59, p. 1-9 9 p.

    Research output: Contribution to journalArticle

  34. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats

    Tronci, E., Napolitano, F., Muñoz, A., Fidalgo, C., Rossi, F., Anders Björklund, Usiello, A. & Carta, M., 2017 Nov 1, In : Experimental Neurology. 297, p. 73-81 9 p.

    Research output: Contribution to journalArticle

  35. TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3)

    Rostgaard, N., Roos, P., Budtz-Jørgensen, E., Johannsen, P., Waldemar, G., Nørremølle, A., Lindquist, S. G., Gydesen, S., Brown, J. M., Collinge, J., Isaacs, A. M., Nielsen, T. T., Nielsen, J. E., E. Englund & FReJA, 2017 Nov 1, In : Neurobiology of Aging. 59, p. 221.e1-221.e7

    Research output: Contribution to journalArticle

  36. Preclinical effects of APOE ϵ4 on cerebrospinal fluid Aβ42 concentrations

    Lautner, R., Philip S. Insel, Skillbäck, T., Olsson, B., Landén, M., Frisoni, G. B., Herukka, S-K., Hampel, H., Wallin, A., Lennart Minthon, Oskar Hansson, Blennow, K., Niklas Mattsson & Zetterberg, H., 2017 Oct 23, In : Alzheimer's Research and Therapy. 9, 1, 87.

    Research output: Contribution to journalArticle

  37. The Swedish study of Irrigation-fluid temperature in the evacuation of Chronic subdural hematoma (SIC!): study protocol for a multicenter randomized controlled trial

    Bartley, A., Jakola, A. S., Bartek, J., Sundblom, J., Förander, P., Niklas Marklund & Tisell, M., 2017 Oct 11, In : Trials. 18, 1, 471.

    Research output: Contribution to journalArticle

  38. Association between cerebrospinal fluid and plasma neurodegeneration biomarkers with brain atrophy in Alzheimer's disease

    Pereira, J. B., Westman, E., Oskar Hansson & Alzheimer's Disease Neuroimaging Initiative, 2017 Oct 1, In : Neurobiology of Aging. 58, p. 14-29

    Research output: Contribution to journalArticle

  39. Ataxia-pancytopenia syndrome with SAMD9L mutations

    Sorina Gorcenco, Komulainen-Ebrahim, J., Nordborg, K., Suo-Palosaari, M., Sten Andréasson, Krüger, J., Nilsson, C., Kjellström, U., Rahikkala, E., Turkiewicz, D., Mikael Karlberg, Nilsson, L., Cammenga, J., Ulf Tedgård, Josef Davidsson, Uusimaa, J. & Andreas Puschmann, 2017 Oct, In : Neurology. Genetics. 3, 5, 7 p., e183.

    Research output: Contribution to journalArticle

  40. Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain

    Thakur, P., Breger, L. S., Lundblad, M., Wan, O. W., Mattsson, B., Luk, K. C., Lee, V. M. Y., Trojanowski, J. Q. & Anders Björklund, 2017 Sep 26, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 39, p. E8284-E8293

    Research output: Contribution to journalArticle

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