MultiPark: Multidisciplinary research focused on Parkinson´s disease

Organisational unit: Strategic research area

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  1. 2019
  2. Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes

    Limbocker, R., Chia, S., Ruggeri, F. S., Perni, M., Cascella, R., Heller, G. T., Meisl, G., Mannini, B., Habchi, J., Michaels, T. C. T., Challa, P. K., Ahn, M., Casford, S. T., Fernando, N., Xu, C. K., Kloss, N. D., Cohen, S. I. A., Kumita, J. R., Cecchi, C., Zasloff, M. & 5 othersSara Linse, Knowles, T. P. J., Chiti, F., Vendruscolo, M. & Dobson, C. M., 2019 Dec 1, In : Nature Communications. 10, 1, 225.

    Research output: Contribution to journalArticle

  3. Pituitary Metastases: A Nationwide Study on Current Characteristics with Special Reference to Breast Cancer

    Fredrika Schill, Nilsson, M., Olsson, D. S., Ragnarsson, O., Berinder, K., Edén Engström, B., Dahlqvist, P., Wahlberg, J., Elisabet Englund & Pia Burman, 2019 Aug, In : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3379-3388 10 p.

    Research output: Contribution to journalArticle

  4. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

    Marie E. Jönsson, Per Ludvik Brattås, Gustafsson, C., Petri, R., David Yudovich, Karolina Pircs, Verschuere, S., Madsen, S., Jenny Hansson, Jonas Larsson, Månsson, R., Meissner, A. & Johan Jakobsson, 2019 Jul 18, In : Nature Communications. 10, 1, 3182.

    Research output: Contribution to journalArticle

  5. PARK2 mutation causes metabolic disturbances and impaired survival of human iPSC-derived neurons

    Bogetofte, H., Jensen, P., Ryding, M., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M. C., Carla Azevedo, Laurent Roybon, Bak, L. K., Waagepetersen, H., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 2019 Jul 5, In : Frontiers in Cellular Neuroscience. 13, 297.

    Research output: Contribution to journalArticle

  6. Associations between quantitative [18F]flortaucipir tau PET and atrophy across the Alzheimer's disease spectrum

    Timmers, T., Rik Ossenkoppele, Wolters, E. E., Verfaillie, S. C. J., Visser, D., Golla, S. S. V., Barkhof, F., Scheltens, P., Boellaard, R., Van Der Flier, W. M. & Van Berckel, B. N. M., 2019 Jul 4, In : Alzheimer's Research and Therapy. 11, 1, 60.

    Research output: Contribution to journalArticle

  7. FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

    Ekaterina Savchenko, Teku, G. N., Antonio Boza-Serrano, Kaspar Russ, Berns, M., Tomas Deierborg, Lamas, N. J., Wichterle, H., Rothstein, J., Henderson, C. E., Mauno Vihinen & Laurent Roybon, 2019 Jul 3, In : Scientific Reports. 9, 1, 9610.

    Research output: Contribution to journalArticle

  8. Danon disease presenting with early onset of hypertrophic cardiomyopathy and peripheral pigmentary retinal dystrophy in a female with a de novo novel mosaic mutation in the LAMP2 gene

    Monika Meinert, Elisabet Englund, Hedberg-Oldfors, C., Oldfors, A., Kornhall, B., Lundin, C. & Wittström, E., 2019 Jul 2, In : Ophthalmic Genetics. 40, 3, p. 227–236 11 p.

    Research output: Contribution to journalArticle

  9. Prognostic value of Alzheimer’s biomarkers in mild cognitive impairment: the effect of age at onset

    for the Alzheimer’s Disease Neuroimaging Initiative, Altomare, D., Ferrari, C., Caroli, A., Galluzzi, S., Prestia, A., van der Flier, W. M., Ossenkoppele, R., Van Berckel, B., Barkhof, F., Teunissen, C. E., Wall, A., Carter, S. F., Schöll, M., Choo, I. H., Grimmer, T., Redolfi, A., Nordberg, A., Scheltens, P., Drzezga, A. & 1 othersFrisoni, G. B., 2019 Jul 2, In : Journal of Neurology.

    Research output: Contribution to journalArticle

  10. Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease

    TRANSEURO consortium, Barker, R. A., Farrell, K., Guzman, N. V., He, X., Lazic, S. E., Moore, S., Morris, R., Tyers, P., Wijeyekoon, R., Daft, D., Hewitt, S., Dayal, V., Foltynie, T., Kefalopoulou, Z., Mahlknecht, P., Lao-Kaim, N. P., Piccini, P., Bjartmarz, H., Björklund, A. & 13 othersOlle Lindvall, Jenny Nelander-Wahlestedt, Malin Parmar, Gesine Paul, Hakan Widner, Church, A., Dunnett, S., Peall, K., Rosser, A., Gurruchaga, J. M., Palfi, S., Piroth, T. & Winkler, C., 2019 Jul, In : Nature Medicine. 25, p. 1045–1053 9 p.

    Research output: Contribution to journalArticle

  11. Oscillations in cortico-basal ganglia circuits: implications for Parkinson's disease and other neurologic and psychiatric conditions

    Pär Halje, Brys, I., Mariman, J. J., da Cunha, C., Fuentes, R. & Per Petersson, 2019 Jul, In : Journal of Neurophysiology. 122, 1, p. 203-231 29 p.

    Research output: Contribution to journalReview article

  12. Primary fatty amides are potential plasma biomarkers for AD

    Niklas Mattsson & Oskar Hansson, 2019 Jun 28, In : Nature Reviews Neurology.

    Research output: Contribution to journalDebate/Note/Editorial

  13. Debatten om det digitala vårdbesöket behöver fler röster

    Kristofer Hansson & Rosengren, H., 2019 Jun 26, Dagens Medicin, 26-34, p. 31.

    Research output: Contribution to specialist publication or newspaperSpecialist publication article

  14. Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease

    Carl Rosenblad, Li, Q., Pioli, E. Y., Dovero, S., Antunes, A. S. L. M., Agúndez, L., Bardelli, M., Linden, R. M., Henckaerts, E., Anders Björklund, Bezard, E. & Tomas Björklund, 2019 Jun 26, In : Brain : a journal of neurology.

    Research output: Contribution to journalArticle

  15. Latent Classes of Cognitive Functioning among Depressed Older Adults Without Dementia

    Morin, R. T., Philip Insel, Nelson, C., Butters, M., Bickford, D., Landau, S., Saykin, A., Weiner, M. & Mackin, R. S., 2019 Jun 24, In : Journal of the International Neuropsychological Society.

    Research output: Contribution to journalArticle

  16. Prevalence of dementia diagnosis not otherwise specified in eight European countries A cross-sectional cohort study

    Connie Lethin, Ingalill Rahm Hallberg, Renom-Guiteras, A., Verbeek, H., Saks, K., Stolt, M., Zabalegui, A., Soto, M. & Nilsson, C., 2019 Jun 24, In : BMC Geriatrics. 19, 1, 172.

    Research output: Contribution to journalArticle

  17. A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

    IMBI Project, Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Oskar Hansson, Nordberg, A. & Jacobs, A. H., 2019 Jun 21, In : Alzheimer's and Dementia.

    Research output: Contribution to journalArticle

  18. Atrophic Myenteric and Submucosal Neurons Are Observed in Parkinson's Disease

    Bodil Ohlsson & Elisabet Englund, 2019 Jun 19, In : Parkinson's Disease. 2019, 5 p., 7935820.

    Research output: Contribution to journalArticle

  19. Disease stage dependency of motor and non-motor fluctuations in Parkinson's disease

    NoMoFlu-PD Study Group, Storch, A., Kristina Rosqvist, Ebersbach, G. & Per Odin, 2019 Jun 19, In : Journal of Neural Transmission.

    Research output: Contribution to journalArticle

  20. The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus

    David Ermert, Laabei, M., Weckel, A., Mörgelin, M., Martin Lundqvist, Lars Björck, Ram, S., Sara Linse & Anna M. Blom, 2019 Jun 4, In : Frontiers in Immunology. 10, JUN, 1230.

    Research output: Contribution to journalArticle

  21. Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

    Alzheimer's Disease Neuroimaging Initiative, AIBL Research Group, Vermunt, L., Åsa Wallin & Visser, P-J., 2019 Jun 1, In : Alzheimer's and Dementia.

    Research output: Contribution to journalArticle

  22. Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrest

    Grand, J., Kjaergaard, J., Niklas Nielsen, Hans Friberg, Tobias Cronberg, Bro-Jeppesen, J., Karsdal, M. A., Nielsen, H. B., Frydland, M., Henriksen, K., Niklas Mattsson, Zetterberg, H. & Hassager, C., 2019 May 31, In : Biomarkers.

    Research output: Contribution to journalArticle

  23. Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia

    Meeter, L. H. H., Steketee, R. M. E., Salkovic, D., Vos, M. E., Grossman, M., McMillan, C. T., Irwin, D. J., Boxer, A. L., Rojas, J. C., Olney, N. T., Karydas, A., Miller, B. L., Pijnenburg, Y. A. L., Barkhof, F., Sánchez-Valle, R., Lladó, A., Borrego-Ecija, S., Diehl-Schmid, J., Grimmer, T., Goldhardt, O. & 27 othersAlexander F. Santillo, Oskar Hansson, Susanne Vestberg, Borroni, B., Padovani, A., Galimberti, D., Scarpini, E., Rohrer, J. D., Woollacott, I. O. C., Synofzik, M., Wilke, C., De Mendonca, A., Vandenberghe, R., Benussi, L., Ghidoni, R., Binetti, G., Niessen, W. J., Papma, J. M., Seelaar, H., Jiskoot, L. C., De Jong, F. J., Donker Kaat, L., Del Campo, M., Teunissen, C. E., Bron, E. E., Van Den Berg, E. & Van Swieten, J. C., 2019 May 28, In : Journal of Neurology, Neurosurgery and Psychiatry. 8 p.

    Research output: Contribution to journalArticle

  24. Elecsys® Total-Tau and Phospho-Tau (181P) CSF assays: Analytical performance of the novel, fully automated immunoassays for quantification of tau proteins in human cerebrospinal fluid

    Lifke, V., Kollmorgen, G., Manuilova, E., Oelschlaegel, T., Hillringhaus, L., Widmann, M., von Arnim, C. A. F., Otto, M., Christenson, R. H., Powers, J. L., Shaw, L. M., Oskar Hansson, Doecke, J. D., Li, Q. X., Teunissen, C., Tumani, H. & Blennow, K., 2019 May 23, In : Clinical Biochemistry.

    Research output: Contribution to journalArticle

  25. Method comparison study of the Elecsys® β-Amyloid (1–42) CSF assay versus comparator assays and LC-MS/MS

    Shaw, L. M., Oskar Hansson, Manuilova, E., Masters, C. L., Doecke, J. D., Li, Q. X., Rutz, S., Widmann, M., Leinenbach, A. & Blennow, K., 2019 May 23, In : Clinical Biochemistry.

    Research output: Contribution to journalArticle

  26. GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

    Rongve, A., Witoelar, A., Ruiz, A., Athanasiu, L., Abdelnour, C., Clarimon, J., Heilmann-Heimbach, S., Hernández, I., Moreno-Grau, S., de Rojas, I., Morenas-Rodríguez, E., Fladby, T., Sando, S. B., Bråthen, G., Blanc, F., Bousiges, O., Lemstra, A. W., van Steenoven, I., Londos, E., Almdahl, I. S. & 20 othersPålhaugen, L., Eriksen, J. A., Djurovic, S., Stordal, E., Saltvedt, I., Ulstein, I. D., Bettella, F., Desikan, R. S., Idland, A. V., Toft, M., Pihlstrøm, L., Snaedal, J., Tárraga, L., Boada, M., Lleó, A., Stefánsson, H., Stefánsson, K., Ramírez, A., Aarsland, D. & Andreassen, O. A., 2019 May 7, In : Scientific Reports. 9, 1, 7013.

    Research output: Contribution to journalArticle

  27. Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study

    Connie Lethin, Ingalill Rahm Hallberg, Saks, K., Soto-Martin, M. E., Renom-Guiteras, A., Zabalegui, A., Stolt, M., Verbeek, H. & Nilsson, C., 2019 May, p. O25:01.

    Research output: Contribution to conferenceAbstract

  28. Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease

    Oskar Hansson, Lehmann, S., Otto, M., Zetterberg, H. & Lewczuk, P., 2019 Apr 22, In : Alzheimer's Research and Therapy. 11, 1, p. 1-15 15 p.

    Research output: Contribution to journalReview article

  29. Association between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients with Alzheimer Disease

    Niklas Mattsson, Cullen, N. C., Andreasson, U., Zetterberg, H. & Blennow, K., 2019 Apr 22, In : JAMA Neurology.

    Research output: Contribution to journalArticle

  30. Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

    Boza-Serrano, A., Ruiz, R., Sanchez-Varo, R., García-Revilla, J., Yang, Y., Jimenez-Ferrer, I., Paulus, A., Wennström, M., Vilalta, A., Allendorf, D., Davila, J. C., Stegmayr, J., Jiménez, S., Roca-Ceballos, M. A., Navarro-Garrido, V., Swanberg, M., Hsieh, C. L., Real, L. M., Englund, E., Linse, S. & 7 othersHakon Leffler, Ulf J. Nilsson, Brown, G. C., Gutierrez, A., Vitorica, J., Venero, J. L. & Tomas Deierborg, 2019 Apr 20, In : Acta Neuropathologica.

    Research output: Contribution to journalArticle

  31. Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism

    Sjöström, H., Yulia Surova, Markus Nilsson, Granberg, T., Westman, E., Danielle van Westen, Svenningsson, P. & Oskar Hansson, 2019 Apr 15, In : Scientific Reports. 9, 1, 6079.

    Research output: Contribution to journalArticle

  32. Relocation of coflowing immiscible liquids under acoustic field in a microchannel

    Hemachandran, E., Karthick, S., T. Laurell & Sen, A. K., 2019 Apr 15, In : EPL. 125, 5, 54002.

    Research output: Contribution to journalArticle

  33. 18 F-Flortaucipir in TDP-43 associated frontotemporal dementia

    R. Smith, A. F. Santillo, M. Landqvist Waldö, O. Strandberg, D. Berron, S. Vestberg, D. van Westen, van Swieten, J., Honer, M. & O. Hansson, 2019 Apr 15, In : Scientific Reports. 9, 1, 6082.

    Research output: Contribution to journalArticle

  34. Incidence of sports-related injuries and illnesses in paralympic athletes: a prospective study during 52 weeks

    Kristina Fagher, Dahlström, Ö., Jacobsson, J., Timpka, T. & Jan Lexell, 2019 Apr, In : British journal of sports medicine. 53, Suppl 1, p. A10 1 p., 27.

    Research output: Contribution to journalPublished meeting abstract

  35. Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia

    Nielsen, T. R., Segers, K., Vanderaspoilden, V., Beinhoff, U., Lennart Minthon, Pissiota, A., Bekkhus-Wetterberg, P., Bjørkløf, G. H., Tsolaki, M., Gkioka, M. & Waldemar, G., 2019 Mar 22, In : International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticle

  36. Bättre behandlad Alzheimers sjukdom kan öka tiden att bo hemma

    Carina Wattmo, 2019 Mar 8, Neurologi i Sverige, 1, 19, p. 48-53.

    Research output: Contribution to specialist publication or newspaperSpecialist publication article

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