MultiPark: Multidisciplinary research focused on Parkinson´s disease

Organisational unit: Strategic research area

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  1. 2018
  2. Heterogeneity in α-synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease

    N. N. Vaikath, Erskine, D., Morris, C. M., Majbour, N. K., Vekrellis, K., J. Y. Li & El-Agnaf, O. M. A., 2018 Nov 13, In : Neuropathology and Applied Neurobiology.

    Research output: Contribution to journalArticle

  3. Study protocol: Care of Late-Stage Parkinsonism (CLaSP): a longitudinal cohort study

    Balzer-Geldsetzer, M., Ferreira, J., Per Odin, Bloem, B. R., Meissner, W. G., Lorenzl, S., Wittenberg, M., Dodel, R. & Schrag, A., 2018 Nov 5, In : BMC Neurology. 18, 1, 185.

    Research output: Contribution to journalArticle

  4. CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

    Oskar Hansson, Seibyl, J., Erik Stomrud, Zetterberg, H., Trojanowski, J. Q., Bittner, T., Lifke, V., Corradini, V., Eichenlaub, U., Batrla, R., Buck, K., Zink, K., Rabe, C., Blennow, K., Shaw, L. M., Swedish BioFINDER study group & Alzheimer's Disease Neuroimaging Initiative, 2018 Nov, In : Alzheimer's and Dementia. 14, 11, p. 1470-1481

    Research output: Contribution to journalArticle

  5. Nano-scale Infrared Imaging of β-sheet Structures in Synaptic Junctions of Primary Neurons Isolated from Transgenic Mice

    O. Klementieva, Mathurin, J., A. Engdahl, Freitas, R., Willen, K., P. Uvdal, Miller, L. M. & G. Gouras, 2018 Oct 29, 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018. IEEE Computer Society, Vol. 2018-September. 8510376

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  6. The Impact of Nonequilibrium Conditions in Lung Surfactant: Structure and Composition Gradients in Multilamellar Films

    Andersson, J. M., Roger, K., Larsson, M. & Emma Sparr, 2018 Oct 24, In : ACS Central Science. 4, 10, p. 1315-1325

    Research output: Contribution to journalArticle

  7. Abnormal structural brain connectome in individuals with preclinical Alzheimer's disease

    Joana B. Pereira, Danielle Van Westen, Erik Stomrud, Strandberg, T. O., Volpe, G., Westman, E. & Oskar Hansson, 2018 Oct 1, In : Cerebral Cortex. 28, 10, p. 3638-3649 12 p.

    Research output: Contribution to journalArticle

  8. Ganglioside lipids accelerate α-synuclein amyloid formation

    Gaspar, R., Jon Pallbo, Weininger, U., Sara Linse & Emma Sparr, 2018 Oct 1, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1866, 10, p. 1062-1072 11 p.

    Research output: Contribution to journalArticle

  9. No association of salivary total tau concentration with Alzheimer's disease

    Ashton, N. J., Ide, M., Michael Schöll, Blennow, K., Lovestone, S., Hye, A. & Zetterberg, H., 2018 Oct 1, In : Neurobiology of Aging. 70, p. 125-127 3 p.

    Research output: Contribution to journalArticle

  10. Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease

    Faustini, G., Longhena, F., Varanita, T., Bubacco, L., Pizzi, M., Missale, C., Benfenati, F., Anders Björklund, Spano, P. F. & Bellucci, A., 2018 Oct 1, In : Acta Neuropathologica. 136, 4, p. 621-639 19 p.

    Research output: Contribution to journalArticle

  11. Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis

    Kutsche, L. K., Gysi, D. M., Fallmann, J., Lenk, K., Petri, R., Swiersy, A., Klapper, S. D., Karolina Pircs, Khattak, S., Stadler, P. F., Johan Jakobsson, Nowick, K. & Busskamp, V., 2018 Oct, In : Cell systems. 7, 4, p. 438-452 15 p.

    Research output: Contribution to journalArticle

  12. Unravelling protein stability and aggregation

    Weiffert, T., 2018 Oct, Lund: Media-Tryck, Lund University, Sweden. 244 p.

    Research output: ThesisDoctoral Thesis (compilation)

  13. α-Synuclein Fibril Formation and the Effects of Lipid Membranes

    Gaspar, R., 2018 Oct, Lund: Physical Chemistry, Lund University. 105 p.

    Research output: ThesisDoctoral Thesis (compilation)

  14. Bidirectional Microglia–Neuron Communication in Health and Disease

    Szepesi, Z., Oscar Manouchehrian, Sara Bachiller & Tomas Deierborg, 2018 Sep 27, In : Frontiers in Cellular Neuroscience. 12, 323.

    Research output: Contribution to journalReview article

  15. Tidig diagnos och behandling med gallsyra avgörande vid cerebrotendinös xantomatos

    Eggertsen, G., Andreas Puschman, Sara Hall, Wärme, A. K., Kvorning, O., Olin, M., Eriksson, M. & Björkhem, I., 2018 Sep 20, In : Läkartidningen. 115, 39

    Research output: Contribution to journalDebate/Note/Editorial

  16. Big-Loop Recurrence within the Hippocampal System Supports Integration of Information across Episodes

    Koster, R., Chadwick, M. J., Chen, Y., David Berron, Banino, A., Düzel, E., Hassabis, D. & Kumaran, D., 2018 Sep 19, In : Neuron. 99, 6, p. 1342-1354.e6

    Research output: Contribution to journalArticle

  17. Discriminative accuracy of [18F]flortaucipir positron emission tomography for Alzheimer disease vs other neurodegenerative disorders

    Ossenkoppele, R., Rabinovici, G. D., Smith, R., Cho, H., Scholl, M., Strandberg, O., Palmqvist, S., Mattsson, N., Janelidze, S., Santillo, A., Ohlsson, T., Jogi, J., Tsai, R., La Joie, R., Kramer, J., Boxer, A. L., Gorno-Tempini, M. L., Miller, B. L., Choi, J. Y., Ryu, Y. H. & 2 othersLyoo, C. H. & Oskar Hansson, 2018 Sep 18, In : JAMA - Journal of the American Medical Association. 320, 11, p. 1151-1162 12 p.

    Research output: Contribution to journalArticle

  18. Disaggregation of gold nanoparticles by Daphnia magna

    Mattsson, K., Aguilar, R., Torstensson, O., Perry, D., Katja Bernfur, Sara Linse, Lars Anders Hansson, Karin S. Åkerfeldt & Tommy Cedervall, 2018 Sep 14, In : Nanotoxicology. 12, 8, p. 885-900

    Research output: Contribution to journalArticle

  19. Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

    Siebzehnrübl, F. A., Raber, K. A., Urbach, Y. K., Schulze-Krebs, A., Canneva, F., Moceri, S., Habermeyer, J., Achoui, D., Gupta, B., Steindler, D. A., Stephan, M., Nguyen, H. P., Bonin, M., Riess, O., Bauer, A., Aigner, L., Couillard-Despres, S., Paucar, M. A., Svenningsson, P., Osmand, A. & 11 othersAndreew, A., Zabel, C., Weiss, A., Kuhn, R., Moussaoui, S., Blockx, I., Van der Linden, A., Rachel Y. Cheong, Laurent Roybon, Åsa Petersén & Von Hörsten, S., 2018 Sep 11, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 37, p. E8765-E8774

    Research output: Contribution to journalArticle

  20. Is intracranial volume a suitable proxy for brain reserve? Rik Ossenkoppele

    Van Loenhoud, A. C., Groot, C., Vogel, J. W., Van Der Flier, W. M. & Rik Ossenkoppele, 2018 Sep 11, In : Alzheimer's Research and Therapy. 10, 1, 91.

    Research output: Contribution to journalReview article

  21. mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease

    Ast, A., Buntru, A., Schindler, F., Hasenkopf, R., Schulz, A., Brusendorf, L., Klockmeier, K., Grelle, G., McMahon, B., Niederlechner, H., Jansen, I., Diez, L., Edel, J., Boeddrich, A., Franklin, S. A., Baldo, B., Schnoegl, S., Kunz, S., Purfürst, B., Gaertner, A. & 6 othersKampinga, H. H., Morton, A. J., Åsa Petersén, Kirstein, J., Bates, G. P. & Wanker, E. E., 2018 Sep 6, In : Molecular Cell. 71, 5, p. 675-688.e6

    Research output: Contribution to journalArticle

  22. Economic Evaluation of Interventions for Screening of Dementia

    Sanjib Saha, Ulf-Göran Gerdtham, Håkan Toresson, Lennart Minthon & Johan Jarl, 2018 Sep 4, 35 p. (Working Papers; no. 2018:20).

    Research output: Working paper

  23. Favorable clinical outcome following surgical evacuation of deep-seated and lobar supratentorial intracerebral hemorrhage: a retrospective single-center analysis of 123 cases

    Hessington, A., Tsitsopoulos, P. P., Fahlström, A. & Niklas Marklund, 2018 Sep 1, In : Acta Neurochirurgica. 160, 9, p. 1737-1747 11 p.

    Research output: Contribution to journalArticle

  24. Management of symptomatic sacral perineural cysts with microsurgery and a vascularized fasciocutaneous flap

    Tsitsopoulos, P. P., Niklas Marklund, Salci, K., Holtz, A. & Mani, M., 2018 Sep, In : Journal of spine surgery (Hong Kong). 4, 3, p. 602-609

    Research output: Contribution to journalArticle

  25. Protein stabilization with retained function of monellin using a split GFP system

    Weiffert, T. & Sara Linse, 2018 Aug 24, In : Scientific Reports. 8, 1, 12763.

    Research output: Contribution to journalArticle

  26. Dementia behaviour management programme at home: impact of a palliative care approach on care managers and professional caregivers of home care services

    Nakanishi, M., Endo, K., Hirooka, K., Nakashima, T., Morimoto, Y., Granvik, E., Lennart Minthon, Katarina Nägga & Nishida, A., 2018 Aug 3, In : Aging and Mental Health. 22, 8, p. 1063-1068

    Research output: Contribution to journalArticle

  27. Special issue: The ageing population – challenges and opportunities (I)

    Susanne Iwarsson, 2018 Aug 1, In : British Journal of Occupational Therapy. 81, 8, p. 425-426 2 p.

    Research output: Contribution to journalDebate/Note/Editorial

  28. Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

    Karolina Pircs, Petri, R., Madsen, S., Brattås, P. L., Vuono, R., Daniella R. Ottosson, St-Amour, I., Hersbach, B. A., Matusiak-Brückner, M., Lundh, S. H., Åsa Petersén, Déglon, N., Hébert, S. S., Malin Parmar, Barker, R. A. & Johan Jakobsson, 2018 Aug, In : Cell Reports. 24, 6, p. 1397-1406 10 p.

    Research output: Contribution to journalArticle

  29. The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective

    Carta, M. & Anders Björklund, 2018 Aug, In : Journal of Neural Transmission. 125, 8, p. 1195-1202

    Research output: Contribution to journalArticle

  30. The Impact of Living with Parkinson's Disease: Balancing within a Web of Needs and Demands

    Catharina Sjödahl Hammarlund, Westergren, A., Åström, I., Edberg, A. K. & Hagell, P., 2018 Jul 29, In : Parkinson's Disease. 2018, 4598651.

    Research output: Contribution to journalArticle

  31. CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease

    Shorena Janelidze, Niklas Mattsson, Erik Stomrud, Olof Lindberg, Sebastian Palmqvist, Zetterberg, H., Blennow, K. & Oskar Hansson, 2018 Jul 27, In : Neurology. 91, 9, p. e867-e877

    Research output: Contribution to journalArticle

  32. Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment

    Salinas, C. B. G., Lu, T. T-H., Sanaz Gabery, Marstal, K., Alanentalo, T., Mercer, A. J., Cornea, A., Conradsen, K., Hecksher-Sørensen, J., Dahl, A. B., Knudsen, L. B. & Secher, A., 2018 Jul 9, In : Scientific Reports. 8, 1, 12 p., 10310.

    Research output: Contribution to journalArticle

  33. Developing defined substrates for stem cell culture and differentiation

    Hagbard, L., Cameron, K., August, P., Penton, C., Malin Parmar, Hay, D. C. & Kallur, T., 2018 Jul 5, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1750, 20170230.

    Research output: Contribution to journalReview article

  34. Dopaminergic effect on non-motor symptoms in late stage Parkinson's disease

    Kristina Rosqvist, Per Odin, Hagell, P., Susanne Iwarsson, Maria H. Nilsson & Storch, A., 2018 Jul 5, In : Journal of Parkinson's Disease. 8, 3, p. 409-420 12 p.

    Research output: Contribution to journalArticle

  35. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

    Tordo, J., O'Leary, C., Antunes, A. S. L. M., Palomar, N., Aldrin-Kirk, P., Basche, M., Bennett, A., D'Souza, Z., Gleitz, H., Godwin, A., Holley, R. J., Parker, H., Liao, A. Y., Rouse, P., Youshani, A. S., Dridi, L., Martins, C., Levade, T., Stacey, K. B., Davis, D. M. & 11 othersDyer, A., Clément, N., Tomas Björklund, Ali, R. R., Agbandje-McKenna, M., Rahim, A. A., Pshezhetsky, A., Waddington, S. N., Linden, R. M., Bigger, B. W. & Henckaerts, E., 2018 Jul 1, In : Brain. 141, 7, p. 2014-2031 18 p.

    Research output: Contribution to journalArticle

  36. Brain pericyte activation occurs early in Huntington's disease

    Padel, T., Michaela Roth, Abderahim Gaceb, Jia Yi Li, Maria Björkqvist & Gesine Paul, 2018 Jul 1, In : Experimental Neurology. 305, p. 139-150 12 p.

    Research output: Contribution to journalArticle

  37. Update on biomarkers for amyloid pathology in Alzheimer's disease

    Ashton, N. J., Michael Schöll, Heurling, K., Gkanatsiou, E., Portelius, E., Höglund, K., Brinkmalm, G., Hye, A., Blennow, K. & Zetterberg, H., 2018 Jul 1, In : Biomarkers in Medicine. 12, 7, p. 799-812 14 p.

    Research output: Contribution to journalReview article

  38. Apolipoprotein E genotypes and longevity across dementia disorders

    Skillbäck, T., Lautner, R., Niklas Mattsson, Schott, J. M., Katarina Nägga, Kilander, L., Wimo, A., Winblad, B., Eriksdotter, M., Blennow, K. & Zetterberg, H., 2018 Jul, In : Alzheimer's and Dementia. 14, 7, p. 895-901

    Research output: Contribution to journalArticle

  39. LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

    International Parkinsonism Genetics Network, Ferreira, J., Cossu, G., Lu, C-S., Meco, G., Cortelli, P., van de Berg, W. D. J. & Bonifati, V., 2018 Jul, In : The Lancet Neurology. 17, 7, p. 597-608

    Research output: Contribution to journalArticle

  40. PDZD8 is not the 'functional ortholog' of Mmm1, it is a paralog

    Wideman, J. G., Balacco, D. L., Tim Fieblinger & Richards, T. A., 2018 Jul, In : F1000Research. 7, p. 1088

    Research output: Contribution to journalArticle

  41. Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

    Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., Frisoni, G. B., Ivanoiu, A., Chételat, G., Resende de Oliveira, C., Rodrigue, K. M., Kornhuber, J., Wallin, A., Klimkowicz-Mrowiec, A., Kandimella, R., Popp, J. & 75 othersAalten, P. P., Aarsland, D., Alcolea, D., Almdahl, I. S., Baldeiras, I., van Buchem, M. A., Cavedo, E., Chen, K., Cohen, A. D., Förster, S., Fortea, J., Frederiksen, K. S., Freund-Levi, Y., Gill, K. D., Gkatzima, O., Grimmer, T., Hampel, H., Herukka, S. K., Johannsen, P., van Laere, K., de Leon, M. J., Maier, W., Marcusson, J., Meulenbroek, O., Møllergård, H. M., Morris, J. C., Mroczko, B., Nordlund, A., Prabhakar, S., Peters, O., Rami, L., Rodríguez-Rodríguez, E., Roe, C. M., Rüther, E., Santana, I., Schröder, J., Seo, S. W., Soininen, H., Spiru, L., Erik Stomrud, Struyfs, H., Teunissen, C. E., Verhey, F. R. J., Vos, S. J. B., van Waalwijk van Doorn, L. J. C., Waldemar, G., Åsa K. Wallin, Wiltfang, J., Vandenberghe, R., Brooks, D. J., Fladby, T., Rowe, C. C., Drzezga, A., Verbeek, M. M., Sarazin, M., Wolk, D. A., Fleisher, A. S., Klunk, W. E., Na, D. L., Sánchez-Juan, P., Lee, D. Y., Nordberg, A., Tsolaki, M., Camus, V., Rinne, J. O., Fagan, A. M., Zetterberg, H., Blennow, K., Rabinovici, G. D., Oskar Hansson, van Berckel, B. N. M., van der Flier, W. M., Scheltens, P., Visser, P. J. & Rik Ossenkoppele, 2018 Jul, In : Alzheimer's and Dementia. 14, 7, p. 913-924

    Research output: Contribution to journalArticle

  42. Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury

    Abu Hamdeh, S., Waara, E. R., Möller, C., Söderberg, L., Basun, H., Alafuzoff, I., Hillered, L., Lannfelt, L., Ingelsson, M. & Niklas Marklund, 2018 Jul, In : Brain Pathology. 28, 4, p. 451-462

    Research output: Contribution to journalArticle

  43. Age-dependent alpha-synuclein accumulation and aggregation in the colon of a transgenic mouse model of Parkinson's disease

    Chen, Q. Q., Caroline Haikal, Wen Li, Li, M. T., Wang, Z. Y. & Jia Yi Li, 2018 Jun 30, In : Translational Neurodegeneration. 7, 1, 13.

    Research output: Contribution to journalArticle

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