MultiPark: Multidisciplinary research focused on Parkinson´s disease

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  1. Article
  2. The Impact of Living with Parkinson's Disease: Balancing within a Web of Needs and Demands

    Catharina Sjödahl Hammarlund, Westergren, A., Åström, I., Edberg, A. K. & Hagell, P., 2018 Jul 29, In : Parkinson's Disease. 2018, 4598651.

    Research output: Contribution to journalArticle

  3. CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease

    Shorena Janelidze, Niklas Mattsson, Erik Stomrud, Olof Lindberg, Sebastian Palmqvist, Zetterberg, H., Blennow, K. & Oskar Hansson, 2018 Jul 27, In : Neurology. 91, 9, p. e867-e877

    Research output: Contribution to journalArticle

  4. Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment

    Salinas, C. B. G., Lu, T. T-H., Sanaz Gabery, Marstal, K., Alanentalo, T., Mercer, A. J., Cornea, A., Conradsen, K., Hecksher-Sørensen, J., Dahl, A. B., Knudsen, L. B. & Secher, A., 2018 Jul 9, In : Scientific Reports. 8, 1, 12 p., 10310.

    Research output: Contribution to journalArticle

  5. Dopaminergic effect on non-motor symptoms in late stage Parkinson's disease

    Kristina Rosqvist, Per Odin, Hagell, P., Susanne Iwarsson, Maria H. Nilsson & Storch, A., 2018 Jul 5, In : Journal of Parkinson's Disease. 8, 3, p. 409-420 12 p.

    Research output: Contribution to journalArticle

  6. Brain pericyte activation occurs early in Huntington's disease

    Padel, T., Michaela Roth, Abderahim Gaceb, Jia Yi Li, Maria Björkqvist & Gesine Paul, 2018 Jul 1, In : Experimental Neurology. 305, p. 139-150 12 p.

    Research output: Contribution to journalArticle

  7. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

    Tordo, J., O'Leary, C., Antunes, A. S. L. M., Palomar, N., Aldrin-Kirk, P., Basche, M., Bennett, A., D'Souza, Z., Gleitz, H., Godwin, A., Holley, R. J., Parker, H., Liao, A. Y., Rouse, P., Youshani, A. S., Dridi, L., Martins, C., Levade, T., Stacey, K. B., Davis, D. M. & 11 othersDyer, A., Clément, N., Tomas Björklund, Ali, R. R., Agbandje-McKenna, M., Rahim, A. A., Pshezhetsky, A., Waddington, S. N., Linden, R. M., Bigger, B. W. & Henckaerts, E., 2018 Jul 1, In : Brain. 141, 7, p. 2014-2031 18 p.

    Research output: Contribution to journalArticle

  8. Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury

    Abu Hamdeh, S., Waara, E. R., Möller, C., Söderberg, L., Basun, H., Alafuzoff, I., Hillered, L., Lannfelt, L., Ingelsson, M. & Niklas Marklund, 2018 Jul, In : Brain Pathology. 28, 4, p. 451-462

    Research output: Contribution to journalArticle

  9. Apolipoprotein E genotypes and longevity across dementia disorders

    Skillbäck, T., Lautner, R., Niklas Mattsson, Schott, J. M., Katarina Nägga, Kilander, L., Wimo, A., Winblad, B., Eriksdotter, M., Blennow, K. & Zetterberg, H., 2018 Jul, In : Alzheimer's and Dementia. 14, 7, p. 895-901

    Research output: Contribution to journalArticle

  10. Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

    Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., Frisoni, G. B., Ivanoiu, A., Chételat, G., Resende de Oliveira, C., Rodrigue, K. M., Kornhuber, J., Wallin, A., Klimkowicz-Mrowiec, A., Kandimella, R., Popp, J. & 75 othersAalten, P. P., Aarsland, D., Alcolea, D., Almdahl, I. S., Baldeiras, I., van Buchem, M. A., Cavedo, E., Chen, K., Cohen, A. D., Förster, S., Fortea, J., Frederiksen, K. S., Freund-Levi, Y., Gill, K. D., Gkatzima, O., Grimmer, T., Hampel, H., Herukka, S. K., Johannsen, P., van Laere, K., de Leon, M. J., Maier, W., Marcusson, J., Meulenbroek, O., Møllergård, H. M., Morris, J. C., Mroczko, B., Nordlund, A., Prabhakar, S., Peters, O., Rami, L., Rodríguez-Rodríguez, E., Roe, C. M., Rüther, E., Santana, I., Schröder, J., Seo, S. W., Soininen, H., Spiru, L., Erik Stomrud, Struyfs, H., Teunissen, C. E., Verhey, F. R. J., Vos, S. J. B., van Waalwijk van Doorn, L. J. C., Waldemar, G., Åsa K. Wallin, Wiltfang, J., Vandenberghe, R., Brooks, D. J., Fladby, T., Rowe, C. C., Drzezga, A., Verbeek, M. M., Sarazin, M., Wolk, D. A., Fleisher, A. S., Klunk, W. E., Na, D. L., Sánchez-Juan, P., Lee, D. Y., Nordberg, A., Tsolaki, M., Camus, V., Rinne, J. O., Fagan, A. M., Zetterberg, H., Blennow, K., Rabinovici, G. D., Oskar Hansson, van Berckel, B. N. M., van der Flier, W. M., Scheltens, P., Visser, P. J. & Rik Ossenkoppele, 2018 Jul, In : Alzheimer's and Dementia. 14, 7, p. 913-924

    Research output: Contribution to journalArticle

  11. LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

    International Parkinsonism Genetics Network, Ferreira, J., Cossu, G., Lu, C-S., Meco, G., Cortelli, P., van de Berg, W. D. J. & Bonifati, V., 2018 Jul, In : The Lancet Neurology. 17, 7, p. 597-608

    Research output: Contribution to journalArticle

  12. PDZD8 is not the 'functional ortholog' of Mmm1, it is a paralog

    Wideman, J. G., Balacco, D. L., Tim Fieblinger & Richards, T. A., 2018 Jul, In : F1000Research. 7, p. 1088

    Research output: Contribution to journalArticle

  13. Age-dependent alpha-synuclein accumulation and aggregation in the colon of a transgenic mouse model of Parkinson's disease

    Chen, Q. Q., Caroline Haikal, Wen Li, Li, M. T., Wang, Z. Y. & Jia Yi Li, 2018 Jun 30, In : Translational Neurodegeneration. 7, 1, 13.

    Research output: Contribution to journalArticle

  14. On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations

    Yang, X., Meisl, G., Frohm, B., Thulin, E., Knowles, T. P. J. & Sara Linse, 2018 Jun 26, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E5849-E5858

    Research output: Contribution to journalArticle

  15. A symphony of stem cells in Vienna - looking to the future

    Porrello, E. R. & Agnete Kirkeby, 2018 Jun 8, In : Development (Cambridge, England). 145, 11

    Research output: Contribution to journalArticle

  16. Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes

    Habchi, J., Chia, S., Galvagnion, C., Michaels, T. C. T., Bellaiche, M. M. J., Ruggeri, F. S., Sanguanini, M., Idini, I., Kumita, J. R., Emma Sparr, Sara Linse, Dobson, C. M., Knowles, T. P. J. & Vendruscolo, M., 2018 Jun, In : Nature Chemistry. 10, 6, p. 673-683

    Research output: Contribution to journalArticle

  17. Inflammation leads to distinct populations of extracellular vesicles from microglia

    Yiyi Yang, Antonio Boza Serrano, Dunning, C., Clausen, B. H., Lambertsen, K. L. & Tomas Deierborg, 2018 May 28, In : Journal of Neuroinflammation.

    Research output: Contribution to journalArticle

  18. Cannula Implantation into the Cisterna Magna of Rodents

    Xavier, A. L. R., Hauglund, N. L., von Holstein-Rathlou, S., Li, Q., Sanggaard, S., Lou, N., Iben Lundgaard & Nedergaard, M., 2018 May 23, In : Journal of visualized experiments : JoVE. 135, e57378.

    Research output: Contribution to journalArticle

  19. Reduced penetrance of the PSEN1 H163Y autosomal dominant Alzheimer mutation: A 22-year follow-up study

    Thordardottir, S., Rodriguez-Vieitez, E., Almkvist, O., Ferreira, D., Saint-Aubert, L., Kinhult-Ståhlbom, A., Thonberg, H., Michael Schöll, Westman, E., Wall, A., Eriksdotter, M., Zetterberg, H., Blennow, K., Nordberg, A. & Graff, C., 2018 May 10, In : Alzheimer's Research and Therapy. 10, 1, 45.

    Research output: Contribution to journalArticle

  20. Prion-like seeding and nucleation of intracellular amyloid-β

    Tomas T. Olsson, Oxana Klementieva & Gunnar K. Gouras, 2018 May 1, In : Neurobiology of Disease. 113, p. 1-10 10 p.

    Research output: Contribution to journalArticle

  21. Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing

    Marcus Davidsson, Díaz-Fernández, P., Torroba, M., Schwich, O. D., Aldrin-Kirk, P., Luis Quintino, Andreas Heuer, Wang, G., Cecilia Lundberg & Tomas Björklund, 2018 May 1, In : RNA. 24, 5, p. 673-687 15 p.

    Research output: Contribution to journalArticle

  22. Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide

    Cohen, S. I. A., Cukalevski, R., Michaels, T. C. T., Šarić, A., Mattias Törnquist, Vendruscolo, M., Dobson, C. M., Buell, A. K., Knowles, T. P. J. & Sara Linse, 2018 May 1, In : Nature Chemistry. 10, 5, p. 523-531 9 p.

    Research output: Contribution to journalArticle

  23. SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies

    Josef Davidsson, Andreas Puschmann, Ulf Tedgård, David Bryder, Nilsson, L. & Cammenga, J., 2018 May, In : Leukemia. 32, 5, p. 1106-1115

    Research output: Contribution to journalArticle

  24. Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity

    Freiburghaus, C., Venera Kuci Emruli, Johansson, A., Eskelund, C. W., Grønbæk, K., Roger Olsson, Fredrik Ek, Mats Jerkeman & Sara Ek, 2018 Apr 25, In : BMC Cancer. 18, 1, 466.

    Research output: Contribution to journalArticle

  25. Glutathione S-transferase alpha 4 prevents dopamine neurodegeneration in a rat alpha-synuclein model of Parkinson's disease

    Jewett, M., Dickson, E., Brolin, K., Negrini, M., Itzia Jimenez-Ferrer & Maria Swanberg, 2018 Apr 6, In : Frontiers in Neurology. 9, APR, 222.

    Research output: Contribution to journalArticle

  26. Generation of an induced pluripotent stem cell line (CSC-41) from a Parkinson's disease patient carrying a p.G2019S mutation in the LRRK2 gene

    Marote, A., Yuriy Pomeshchik, Collin, A., Goldwurm, S., Lamas, N. J., Pinto, L., Salgado, A. J. & Laurent Roybon, 2018 Apr 1, In : Stem Cell Research. 28, p. 44-47 4 p.

    Research output: Contribution to journalArticle

  27. Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model

    Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, J. T., Maria Björkqvist, Silahtaroglu, A., Hasholt, L. & Nørremølle, A., 2018 Apr 1, In : Molecular and Cellular Neuroscience. 88, p. 118-129 12 p.

    Research output: Contribution to journalArticle

  28. Neurophysiological effects in cortico-basal ganglia-thalamic circuits of antidyskinetic treatment with 5-HT1A receptor biased agonists

    Brys, I., Pär Halje, Scheffer-Teixeira, R., Varney, M., Newman-Tancredi, A. & Per Petersson, 2018 Apr 1, In : Experimental Neurology. 302, p. 155-168 14 p.

    Research output: Contribution to journalArticle

  29. Glioma grade discrimination with MR diffusion kurtosis imaging: A meta-Analysis of diagnostic accuracy

    Delgado, A. F., Markus Nilsson, Danielle Van Westen & Delgado, A. F., 2018 Apr 1, In : Radiology. 287, 1, p. 119-127 9 p.

    Research output: Contribution to journalArticle

  30. Amyloid pathology in the progression to mild cognitive impairment

    Philip S. Insel, Oskar Hansson, Mackin, R. S., Weiner, M., Niklas Mattsson & Alzheimer's Disease Neuroimaging Initiative, 2018 Apr, In : Neurobiology of Aging. 64, p. 76-84 9 p.

    Research output: Contribution to journalArticle

  31. Editorial: Monitoring pathophysiology in the injured brain

    Thelin, E. P., Helmy, A., Nelson, D. W. & Niklas Marklund, 2018 Mar 26, In : Frontiers in Neurology. 9, MAR, 193.

    Research output: Contribution to journalArticle

  32. Conformational Ensembles of Calmodulin Revealed by Nonperturbing Site-Specific Vibrational Probe Groups

    Kelly, K. L., Dalton, S. R., Wai, R. B., Ramchandani, K., Xu, R. J., Sara Linse & Londergan, C. H., 2018 Mar 22, In : Journal of Physical Chemistry A. 122, 11, p. 2947-2955 9 p.

    Research output: Contribution to journalArticle

  33. Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

    Mondal, T., Juvvuna, P. K., Kirkeby, A., Mitra, S., Kosalai, S. T., Traxler, L., Hertwig, F., Wernig-Zorc, S., Miranda, C., Deland, L., Volland, R., Bartenhagen, C., Bartsch, D., Bandaru, S., Engesser, A., Subhash, S., Martinsson, T., Carén, H., Akyürek, L. M., Kurian, L. & 4 othersKanduri, M., Huarte, M., Kogner, P. & Fischer, M., 2018 Mar 12, In : Cancer Cell. 33, 3, p. 417-434.e7

    Research output: Contribution to journalArticle

  34. Generation of an integration-free induced pluripotent stem cell line (CSC-43J) from a patient with sporadic Parkinson's disease

    Marote, A., Yuriy Pomeshchik, Goldwurm, S., Collin, A., Lamas, N. J., Pinto, L., Salgado, A. J. & Laurent Roybon, 2018 Mar 1, In : Stem Cell Research. 27, p. 82-85 4 p.

    Research output: Contribution to journalArticle

  35. Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease

    Ekaterina Savchenko, Marote, A., Kaspar Russ, Collin, A., Goldwurm, S., Laurent Roybon & Yuriy Pomeshchik, 2018 Mar 1, In : Stem Cell Research. 27, p. 78-81 4 p.

    Research output: Contribution to journalArticle

  36. Generation of an induced pluripotent stem cell line (CSC-44) from a Parkinson's disease patient carrying a compound heterozygous mutation (c.823C > T and EX6 del) in the PARK2 gene

    Marote, A., Yuriy Pomeshchik, Goldwurm, S., Collin, A., Lamas, N. J., Pinto, L., Salgado, A. J. & Laurent Roybon, 2018 Mar 1, In : Stem Cell Research. 27, p. 90-94 5 p.

    Research output: Contribution to journalArticle

  37. MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo

    Saraiva, C., Daniela Talhada, Rai, A., Ferreira, R., Ferreira, L., Bernardino, L. & Karsten Ruscher, 2018 Mar 1, In : PLoS ONE. 13, 3, e0193609.

    Research output: Contribution to journalArticle

  38. Development of a Sol-gel-assisted Reverse-phase Microarray Platform for Simple and Rapid Detection of Prostate-specific Antigen from Serum

    Lee, S. W., Thomas Laurell, Jeong, O. C. & Kim, S., 2018 Mar 1, In : Biochip Journal. 12, 1, p. 69-74 6 p.

    Research output: Contribution to journalArticle

  39. Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

    VICCCS group, Skrobot, O. A., Black, S. E., Chen, C., DeCarli, C., Erkinjuntti, T., Ford, G. A., Kalaria, R. N., O'Brien, J., Pantoni, L., Pasquier, F., Roman, G. C., Wallin, A., Sachdev, P., Skoog, I. & E. Englund, 2018 Mar 1, In : Alzheimer's and Dementia. 14, 3, p. 280-292 13 p.

    Research output: Contribution to journalArticle

  40. Molecularly imprinted polymers synthesized via template immobilization on fumed silica nanoparticles for the enrichment of phosphopeptides

    Nogueira Duarte, M., Subedi, P., Yilmaz, E., Marcus, K., Thomas Laurell & Simon Ekström, 2018 Mar, In : Journal of Molecular Recognition. 31, 3, p. e2677

    Research output: Contribution to journalArticle

  41. Psychosocial behaviour management programme for home-dwelling people with dementia: A cluster-randomized controlled trial

    Nakanishi, M., Endo, K., Hirooka, K., Granvik, E., Lennart Minthon, Katarina Nägga & Nishida, A., 2018 Mar, In : International Journal of Geriatric Psychiatry. 33, 3, p. 495-503 9 p.

    Research output: Contribution to journalArticle

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