Stem Cell Center

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  1. Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia

    European Research Initiative on CLL (ERIC), Baliakas, P., Moysiadis, T., Hadzidimitriou, A., Xochelli, A., Jeromin, S., Agathangelidis, A., Mattsson, M., Sutton, L. A., Minga, E., Scarfò, L., Rossi, D., Davis, Z., Villamor, N., Parker, H., Kotaskova, J., Stalika, E., Plevova, K., Mansouri, L., Cortese, D. & 20 othersNavarro, A., Delgado, J., Larrayoz, M., Young, E., Anagnostopoulos, A., Smedby, K. E., Gunnar Juliusson, Sheehy, O., Catherwood, M., Strefford, J. C., Stavroyianni, N., Belessi, C., Pospisilova, S., Oscier, D., Gaidano, G., Campo, E., Haferlach, C., Ghia, P., Rosenquist, R. & Stamatopoulos, K., 2019, In : Haematologica. 104, 2, p. 360-369 10 p.

    Research output: Contribution to journalArticle

  2. Mechanisms of anti-cancer action and pharmacology of clofarabine

    Zhenchuk, A., Lotfi, K., Gunnar Juliusson & Albertioni, F., 2009, In : Biochemical Pharmacology. 78, 11, p. 1351-1359

    Research output: Contribution to journalDebate/Note/Editorial

  3. Inhibition of p300/CBP by early B-cell factor

    Zhao, F., McCarrick-Walmsley, R., Åkerblad, P., Mikael Sigvardsson & Kadesch, T., 2003, In : Molecular and Cellular Biology. 23, 11, p. 3837-3846

    Research output: Contribution to journalArticle

  4. Lentiviral vector-mediated down-regulation of IL-17A receptor in hepatic stellate cells results in decreased secretion of IL-6

    Zhang, S-C., Zheng, Y-H., Yu, P-P., Hooi Min Tan Grahn, Yu, F-X., Ye, C., Xie, Y-K. & Zhang, Q-Y., 2012, In : World Journal of Gastroenterology. 18, 28, p. 3696-3704

    Research output: Contribution to journalArticle

  5. Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication

    Zetterblad, J., Qian, H., Zandi, S., Månsson, R., Lagergren, A., Hansson, F., David Bryder, Paulsson, N. & Mikael Sigvardsson, 2010, In : BMC Genomics. 11, 108.

    Research output: Contribution to journalArticle

  6. EBF1 is essential for B-Lineage priming and establishment of a transcription factor network in common lymphoid progenitors

    Zandi, S., Månsson, R., Tsapogas, P., Zetterblad, J., David Bryder & Mikael Sigvardsson, 2008, In : Journal of Immunology. 181, 5, p. 3364-3372

    Research output: Contribution to journalArticle

  7. Load and lock: the molecular mechanisms of B-lymphocyte commitment.

    Zandi, S., David Bryder & Mikael Sigvardsson, 2010, In : Immunological Reviews. 238, 1, p. 47-62

    Research output: Contribution to journalArticle

  8. TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia

    Zainuddin, N., Murray, F., Kanduri, M., Rebeqa Gunnarsson, Smedby, K. E., Enblad, G., Jurlander, J., Gunnar Juliusson & Rosenquist, R., 2011, In : Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis. 35, 2, p. 272-274

    Research output: Contribution to journalArticle

  9. Identification of Lin-Sca1+kit+CD34+Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated recipients.

    Yang, L., David Bryder, Adolfsson, J., Nygren, J., Månsson, R., Mikael Sigvardsson & Jacobsen, S. E. W., 2005, In : Blood. 105, 7, p. 2717-2723

    Research output: Contribution to journalArticle

  10. Cellular and Molecular Pathways Governing Hematopoietic Stem Cell Fate

    Yang, L., 2006, Lund Center for Stem Cell Biology and Cell Therapy.

    Research output: ThesisDoctoral Thesis (compilation)

  11. IFN-{gamma} Negatively Modulates Self-Renewal of Repopulating Human Hemopoietic Stem Cells.

    Yang, L., Dybedal, I., David Bryder, Nilsson, L., Ewa Sitnicka Quinn, Sasaki, Y. & Jacobsen, S. E. W., 2005, In : Journal of Immunology. 174, 2, p. 752-757

    Research output: Contribution to journalArticle

  12. Chronic lymphocytic leukemia with mutated IGHV4-34 receptors: Shared and distinct immunogenetic features and clinical outcomes

    Xochelli, A., Baliakas, P., Kavakiotis, I., Agathangelidis, A., Sutton, L-A., Minga, E., Ntoufa, S., Tausch, E., Yan, X-J., Shanafelt, T., Plevova, K., Boudjogra, M., Rossi, D., Davis, Z., Navarro, A., Sandberg, Y., Vojdeman, F. J., Scarfo, L., Stavroyianni, N., Sudarikov, A. & 42 othersVeronese, S., Tzenou, T., Karan-Djurasevic, T., Catherwood, M., Kienle, D., Chatzouli, M., Facco, M., Bahlo, J., Pott, C., Pedersen, L. B., Mansouri, L., Smedby, K. E., Chu, C. C., Giudicelli, V., Lefranc, M-P., Panagiotidis, P., Gunnar Juliusson, Anagnostopoulos, A., Vlahavas, I., Antic, D., Trentin, L., Montillo, M., Niemann, C., Dohner, H., Langerak, A. W., Pospisilova, S., Hallek, M., Campo, E., Chiorazzi, N., Maglaveras, N., Oscier, D., Gaidano, G., Jelinek, D. F., Stilgenbauer, S., Chouvarda, I., Darzentas, N., Belessi, C., Davi, F., Hadzidimitriou, A., Rosenquist, R., Ghia, P. & Stamatopoulos, K., 2017 Sep 1, In : Clinical Cancer Research. 23, 17, p. 5292-5301 10 p.

    Research output: Contribution to journalArticle

  13. Pericytes limit tumor cell metastasis.

    Xiaojie Xian, Hakansson, J., Ståhlberg, A., Lindblom, P., Betsholtz, C., Gerhardt, H. & Semb, H., 2006, In : Journal of Clinical Investigation. 116, 3, p. 642-651

    Research output: Contribution to journalArticle

  14. Expression of Integrin A2 Receptor in Human Cord Blood Cd34+Cd38-Cd90+ Stem Cells Engrafting Long-Term in Nod/Scid-Il2rγ(C) Null Mice.

    Wong, W. M., Mikael Sigvardsson, Åstrand-Grundström, I., Hogge, D., Jonas Larsson, Qian, H. & Marja Ekblom, 2013, In : Stem Cells. 31, 2, p. 360-371

    Research output: Contribution to journalArticle

  15. Integrin α2 and Akt in early hematopoiesis

    Wong, W. M., 2013, Stem Cell Center, Lund University. 87 p.

    Research output: ThesisDoctoral Thesis (compilation)

  16. A novel Lin-CD34+CD38-integrin α2- bipotential megakaryocyte-erythrocyte progenitor population in human bone marrow.

    Wong, W. M., Dolinska, M., Mikael Sigvardsson, Marja Ekblom & Qian, H., 2015, In : Leukemia. 30, p. 1399-1402

    Research output: Contribution to journalArticle

  17. Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo.

    Woll, P. S., Kjällquist, U., Chowdhury, O., Doolittle, H., Wedge, D. C., Thongjuea, S., Erlandsson, R., Ngara, M., Anderson, K., Deng, Q., Mead, A. J., Stenson, L., Giustacchini, A., Duarte, S., Giannoulatou, E., Taylor, S., Karimi, M., Scharenberg, C., Mortera-Blanco, T., Macaulay, I. C. & 28 othersClark, S-A., Dybedal, I., Josefsen, D., Fenaux, P., Hokland, P., Holm, M. S., Cazzola, M., Malcovati, L., Tauro, S., Bowen, D., Boultwood, J., Pellagatti, A., Pimanda, J. E., Unnikrishnan, A., Vyas, P., Göhring, G., Schlegelberger, B., Tobiasson, M., Kvalheim, G., Constantinescu, S. N., Nerlov, C., Nilsson, L., Campbell, P. J., Sandberg, R., Papaemmanuil, E., Hellström-Lindberg, E., Linnarsson, S. & Jacobsen, S. E. W., 2014, In : Cancer Cell. 25, 6, p. 794-808

    Research output: Contribution to journalArticle

  18. Growth-limiting role of endothelial cells in endoderm development.

    Wolfhagen Sand, F., Hörnblad, A., Johansson, J., Lorén, C., Edsbagge, J., Ståhlberg, A., Magenheim, J., Ilovich, O., Mishani, E., Dor, Y., Ahlgren, U. & Semb, H., 2011, In : Developmental Biology. 352, 2, p. 267-277

    Research output: Contribution to journalArticle

  19. ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

    Wolfhagen Sand, F., 2011, Stem Cell Center, Lund University. 196 p.

    Research output: ThesisDoctoral Thesis (compilation)

  20. MDM2 SNP309 promoter polymorphism, an independent prognostic factor in chronic lymphocytic leukemia

    Willander, K., Ungerback, J., Karlsson, K., Fredrikson, M., Soderkvist, P. & Linderholm, M., 2010, In : European Journal of Haematology. 85, 3, p. 251-256

    Research output: Contribution to journalArticle

  21. NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients

    Willander, K., Dutta, R. K., Ungerback, J., Rebeqa Gunnarsson, Gunnar Juliusson, Fredrikson, M., Linderholm, M. & Soderkvist, P., 2013, In : BMC Cancer. 13, 274.

    Research output: Contribution to journalArticle

  22. Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

    Went, M., Sud, A., Speedy, H., Sunter, N. J., Försti, A., Law, P. J., Johnson, D. C., Mirabella, F., Holroyd, A., Li, N., Orlando, G., Weinhold, N., van Duin, M., Chen, B., Mitchell, J. S., Mansouri, L., Juliusson, G., Smedby, K. E., Jayne, S., Majid, A. & 35 othersDearden, C., Allsup, D. J., Bailey, J. R., Pratt, G., Pepper, C., Fegan, C., Rosenquist, R., Kuiper, R., Stephens, O. W., Bertsch, U., Broderick, P., Einsele, H., Gregory, W. M., Hillengass, J., Hoffmann, P., Jackson, G. H., Jöckel, K. H., Nickel, J., Nöthen, M. M., da Silva Filho, M. I., Hauke Thomsen, Walker, B. A., Broyl, A., Davies, F. E., Markus Hansson, Goldschmidt, H., Dyer, M. J. S., Kaiser, M., Sonneveld, P., Morgan, G. J., Kari Hemminki, Björn Nilsson, Catovsky, D., Allan, J. M. & Houlston, R. S., 2018 Dec 21, In : Blood Cancer Journal. 9, 1, 1.

    Research output: Contribution to journalArticle

  23. Acute myeloid leukemia in adolescents and young adults treated in pediatric and adult departments in the nordic countries.

    Wennström, L., Edslev, P. W., Abrahamsson, J., Nørgaard, J. M., Fløisand, Y., Forestier, E., Gustafsson, G., Heldrup, J., Hovi, L., Jahnukainen, K., Jonsson, O. G., Lausen, B., Palle, J., Zeller, B., Holmberg, E., Gunnar Juliusson, Stockelberg, D. & Hasle, H., 2016, In : Pediatric Blood & Cancer. 63, 1, p. 83-92

    Research output: Contribution to journalArticle

  24. B-lymphocyte commitment: Identifying the point of no return.

    Welinder, E., Ahsberg, J. & Mikael Sigvardsson, 2011, In : Seminars in Immunology. 23, p. 335-340

    Research output: Contribution to journalArticle

  25. Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells.

    Weishaupt, H., Mikael Sigvardsson & Attema, J., 2010, In : Blood. 115, p. 247-256

    Research output: Contribution to journalArticle

  26. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

    Weischenfeldt, J., Damgaard, I., David Bryder, Theilgaard-Moench, K., Thorén, L., Nielsen, F. C., Jacobsen, S. E. W., Nerlov, C. & Porse, B. T., 2008, In : Genes & Development. 22, 10, p. 1381-1396

    Research output: Contribution to journalArticle

  27. The role of VEGF and a functional link between VEGF and p27(Kip1) in acute myeloid leukemia.

    Wegiel, B., Ekberg, J., Talasila, K. M., Jalili, S. & Persson, J. L., 2009, In : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2008, Nov 6., p. 251-261

    Research output: Contribution to journalArticle

  28. Monocyte-derived macrophages contribute to spontaneous long-term functional recovery after stroke in mice

    Wattananit, S., Tornero, D., Graubardt, N., Memanishvili, T., Emanuela Monni, Tatarishvili, J., Miskinyte, G., Ge, R., Henrik Ahlenius, Olle Lindvall, Schwartz, M. & Zaal Kokaia, 2016 Apr 13, In : Journal of Neuroscience. 36, 15, p. 4182-4195 14 p.

    Research output: Contribution to journalArticle

  29. Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML

    Rebecca Warfvinge, Linda Geironson Ulfsson, Mikael N E Sommarin, Stefan Lang, Christine Karlsson, Roschupkina, T., Stenke, L., Stentoft, J., Olsson-Strömberg, U., Hjorth-Hansen, H., Mustjoki, S., Shamit Soneji, Johan Richter & Göran Karlsson, 2017 Apr, In : Blood. 129, 17, p. 2384-2394

    Research output: Contribution to journalArticle

  30. P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells.

    Wang, L., Jacobsen, S. E. W., Anders Bengtsson & David Erlinge, 2004, In : BMC Immunology. 5, 1, p. 16-16

    Research output: Contribution to journalArticle

  31. Cardiomyocyte Cell Cycle, Renewal and Isolation

    Walsh, S., 2010, Cardiovascular Laboratory, Center for Stem Cell Biology, Lund. 117 p.

    Research output: ThesisDoctoral Thesis (compilation)

  32. Cardiomyocyte cell cycle control and growth estimation in vivo- an analysis based on cardiomyocyte nuclei.

    Walsh, S., Pontén, A., Fleischmann, B. K. & Jovinge, S., 2010, In : Cardiovascular Research. 86, 3, p. 365-373

    Research output: Contribution to journalArticle

  33. Myogenic Reprogramming of Bone Marrow Derived Cells in a WDmd Deficient Mouse Model.

    Walsh, S., Nygren, J., Pontén, A. & Jovinge, S., 2011, In : PLoS ONE. 6, 11, e27500.

    Research output: Contribution to journalArticle

  34. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

    Martin Wahlestedt, Norddahl, G., Sten, G., Amol Ugale, Micha Frisk, M-A., Mattsson, R., Tomas Deierborg, Mikael Sigvardsson & David Bryder, 2013, In : Blood. 121, 21, p. 4257-4264

    Research output: Contribution to journalArticle

  35. Co-opting of ClinicalTrials.gov by patient-funded studies

    Darcy E. Wagner, Turner, L., Panoskaltsis-Mortari, A., Weiss, D. J. & Ikonomou, L., 2018 Aug, In : The Lancet Respiratory Medicine. 6, 8, p. 579-581

    Research output: Contribution to journalArticle

  36. Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma

    Waage, A., Gimsing, P., Fayers, P., Abildgaard, N., Ahlberg, L., Bjorkstrand, B., Carlson, K., Dahl, I. M., Forsberg, K., Gulbrandsen, N., Haukas, E., Hjertner, O., Hjorth, M., Karlsson, T., Knudsen, L. M., Nielsen, J. L., Linder, O., Mellqvist, U-H., Nesthus, I., Rolke, J. & 5 othersStrandberg, M., Sorbo, J. H., Wisloff, F., Gunnar Juliusson & Ingemar Turesson, 2010, In : Blood. 116, 9, p. 1405-1412

    Research output: Contribution to journalArticle

  37. Early response predicts thalidomide efficiency in patients with advanced multiple myeloma

    Waage, A., Gimsing, P., Juliusson, G., Ingemar Turesson, Gulbrandsen, N., Eriksson, T., Hjorth, M., Nielsen, JL., Lenhoff, S., Westin, J. & Wisloff, F., 2004, In : British Journal of Haematology. 125, 2, p. 149-155

    Research output: Contribution to journalArticle

  38. RNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development.

    Tsapogas, P., Breslin, T., Bilke, S., Lagergren, A., Månsson, R., Liberg, D., Peterson, C. & Mikael Sigvardsson, 2003, In : Journal of Leukocyte Biology. 74, 1, p. 102-110

    Research output: Contribution to journalArticle

  39. CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization

    Tormin, A., Li, O., Brune, J. C., Walsh, S., Schütz, B., Mats Ehinger, Ditzel, N., Kassem, M. & Stefan Scheding, 2011, In : Blood. 117, 19, p. 5067-5077

    Research output: Contribution to journalArticle

  40. CD146 expression of primary bone marrow MSC progenitor/stem cells is regulated by hypoxia and correlates with in vivo location

    Tormin, A., Li, O., Brune, J. C. & Stefan Scheding, 2010, In : Bone Marrow Transplantation. 45, p. S326-S326

    Research output: Contribution to journalPublished meeting abstract

  41. CD146 Expression in Primary Bone Marrow MSC Progenitor/Stem Cells Is Dependent On Their In Vivo Location

    Tormin, A., Li, O., Walsh, S., Mats Ehinger, Brune, J. C. & Stefan Scheding, 2009, In : Blood. 114, 22, p. 107-107

    Research output: Contribution to journalPublished meeting abstract

  42. Characterization of bone marrow-derived mesenchymal stromal cells (MSC) based on gene expression profiling of functionally defined MSC subsets.

    Tormin, A., Brune, J. C., Olsson, E., Valcich, J., Neuman, U., Olofsson, T., Jacobsen, S. E. W. & Stefan Scheding, 2009, In : Cytotherapy. 11, p. 114-128

    Research output: Contribution to journalArticle

  43. High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle

    Tipping, A. J., Pina, C., Anders Castor, Hong, D., Rodrigues, N. P., Lazzari, L., May, G. E., Jacobsen, S. E. W. & Enver, T., 2009, In : Blood. 113, 12, p. 2661-2672

    Research output: Contribution to journalArticle

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