Stem Cell Center

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  1. 450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments

    Cahill, N., Bergh, A-C., Kanduri, M., Goransson-Kultima, H., Mansouri, L., Isaksson, A., Ryan, F., Smedby, K. E., Gunnar Juliusson, Sundstrom, C., Rosen, A. & Rosenquist, R., 2013, In : Leukemia. 27, 1, p. 150-158

    Research output: Contribution to journalArticle

  2. Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML

    O Lindblad, Cordero, E., Puissant, A., Macaulay, L., Ramos, A., Kabir, N. N., J Sun, J Vallon-Christersson, Haraldsson, K., Hemann, M. T., Åke Borg, F Levander, Stegmaier, K., K Pietras, L Rönnstrand & J U Kazi, 2016 Sep 29, In : Oncogene. 35, 39, p. 5119-5131 13 p.

    Research output: Contribution to journalArticle

  3. Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes

    Tehranchi, R., Invernizzi, R., Grandien, A., Zhivotovsky, B., Fadeel, B., Forsblom, AM., Travaglino, E., Samuelsson, J., Hast, R., Nilsson, L., Cazzola, M., Wibom, R. & Hellstrom-Lindberg, E., 2005, In : Blood. 106, 1, p. 247-253

    Research output: Contribution to journalArticle

  4. ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

    Julhash U Kazi, Rupar, K., Marhäll, A., Sausan A Moharram, Khanum, F., Kinjal Shah, Mohiuddin, G., Mysore Nagaraj, S. R., Jianmin Sun, Chougule, R. A. & Lars Rönnstrand, 2017, In : Oncotarget. 8, 7, p. 12194-12202

    Research output: Contribution to journalArticle

  5. Ablation of FGFR2b in a subset of pdx1+pancreatic progenitor cells

    Löf-Öhlin, Z., Nyeng, P., Isabella Artner & Semb, H., 2010, In : Diabetologia. 53, Suppl. 1, p. 469

    Research output: Contribution to journalPublished meeting abstract

  6. Abnormalnosti hromozoma 17 kod bolesnika sa primarnim mijeloidisplasticnih sindromima: incidencija i bioloski znacaj

    Marisavljević, D., Rolović, Z., Panitić, M., Novak, A., Djordjević, V., LAZAREVIC, VLADIMIR., Bosković, D. & Colović, M., 2004 Jul 2, In : Srpski Arhiv Za Celokupno Lekarstvo. 132, 1-2, p. 10-3 4 p.

    Research output: Contribution to journalArticle

  7. Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice.

    Eva Bengtsson, To, F., Anders Grubb, Håkansson, K., Wittgren, L., Jan Nilsson & Jovinge, S., 2005, In : Atherosclerosis. 180, 1, p. 45-53

    Research output: Contribution to journalArticle

  8. Acellular human lung scaffolds to model lung disease and tissue regeneration

    Gilpin, S. E. & Darcy E. Wagner, 2018 Jun 30, In : European Respiratory Review. 27, 148, 180021.

    Research output: Contribution to journalArticle

  9. A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, A., Porse, B. T. & Theilgaard-Moench, K., 2010, In : Leukemia. 24, 7, p. 1265-1275

    Research output: Contribution to journalArticle

  10. Acoustic Enrichment of Extracellular Vesicles from Biological Fluids

    Anson Ku, Hooi Ching Lim, Mikael Evander, Lilja, H., Thomas Laurell, Stefan Scheding & Yvonne Ceder, 2018, In : Analytical Chemistry. 90, 13, p. 8011-8019 9 p.

    Research output: Contribution to journalArticle

  11. Acoustofluidic hematocrit determination

    Petersson, K., Jakobsson, O., Pelle Ohlsson, Per Augustsson, Stefan Scheding, Johan Malm & Thomas Laurell, 2018, In : Analytica Chimica Acta. 1000, p. 199-204

    Research output: Contribution to journalArticle

  12. A critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.

    Jimenez, M. A., Akerblad, P., Mikael Sigvardsson & Rosen, E. D., 2007, In : Molecular and Cellular Biology. 27, Oct 23, p. 743-757

    Research output: Contribution to journalArticle

  13. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

    Kirstetter, P., Anderson, K., Porse, B. T., Jacobsen, S. E. W. & Nerlov, C., 2006, In : Nature Immunology. 7, 10, p. 1048-1056

    Research output: Contribution to journalArticle

  14. Active signals, gradient formation and regional specificity in neural induction.

    Edgar Pera, Acosta, H., Gouignard, N., Climent, M. & Arregi, I., 2014, In : Experimental Cell Research. 321, 1, p. 25-31

    Research output: Contribution to journalReview article

  15. Acute megakaryoblastic leukaemia in a patient with systemic lupus erythematosus

    Colović, M., Janković, G., LAZAREVIC, VLADIMIR. & Novak, A., 1997 Mar, In : Medical Oncology. 14, 1, p. 31-4 4 p.

    Research output: Contribution to journalArticle

  16. Acute myeloid leukemia in adolescents and young adults treated in pediatric and adult departments in the nordic countries.

    Wennström, L., Edslev, P. W., Abrahamsson, J., Nørgaard, J. M., Fløisand, Y., Forestier, E., Gustafsson, G., Heldrup, J., Hovi, L., Jahnukainen, K., Jonsson, O. G., Lausen, B., Palle, J., Zeller, B., Holmberg, E., Gunnar Juliusson, Stockelberg, D. & Hasle, H., 2016, In : Pediatric Blood & Cancer. 63, 1, p. 83-92

    Research output: Contribution to journalArticle

  17. Acute myeloid leukemia in the real world: why population-based registries are needed.

    Gunnar Juliusson, Lazarevic, V., Hörstedt, A., Oskar Hagberg & Hoglund, M., 2012, In : Blood. 119, 17, p. 3890-3899

    Research output: Contribution to journalArticle

  18. Acute myeloid leukemia in very old patients

    Lazarevic, V. L., Anders Bredberg, Lorenz, F., Ölander, E., Antunovic, P., Cammenga, J., Wennström, L., Möllgård, L., Deneberg, S., Derolf, Å., Höglund, M. & Gunnar Juliusson, 2018, In : Haematologica. 103, 12, p. e578-e580

    Research output: Contribution to journalArticle

  19. Adaptor Protein LNK Is a Negative Regulator of Brain Neural Stem Cell Proliferation after Stroke.

    Henrik Ahlenius, Devaraju, K., Emanuela Monni, Oki, K., Wattananit, S., Darsalia, V., Iosif, R., Torper, O., Wood, J., Sebastian Braun, Jagemann, L., Nuber, U., Elisabet Englund, Jacobsen, S. E. W., Olle Lindvall & Zaal Kokaia, 2012, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 32, 15, p. 5151-5164

    Research output: Contribution to journalArticle

  20. A dose-dependent role for EBF1 in repressing non-B-cell-specific genes

    Lukin, K., Fields, S., Guerrettaz, L., Straign, D., Rodriguez, V., Zandi, S., Månsson, R., Cambier, J. C., Mikael Sigvardsson & Hagman, J., 2011, In : European Journal of Immunology. 41, 6, p. 1787-1793

    Research output: Contribution to journalArticle

  21. Advances in stem cell research and therapeutic development

    De Luca, M., Aiuti, A., Cossu, G., Malin Parmar, Pellegrini, G. & Robey, P. G., 2019, In : Nature Cell Biology. 21, 7, p. 801-811 11 p.

    Research output: Contribution to journalReview article

  22. Adverse effects and benefits of two years of anagrelide treatment for thrombocythemia in chronic myeloproliferative disorders

    Birgegard, G., Bjorkholm, M., Kutti, J., Larfars, G., Lofvenberg, E., Markevarn, B., Merup, M., Palmblad, J., Mauritzson, N., Westin, J. & Samuelsson, J., 2004, In : Haematologica. 89, 5, p. 520-527

    Research output: Contribution to journalArticle

  23. Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry

    Gunnar Juliusson, Antunovic, P., Derolf, A., Lehmann, S., Mollgard, L., Stockelberg, D., Tidefelt, U., Wahlin, A. & Hoglund, M., 2009, In : Blood. 113, 18, p. 4179-4187

    Research output: Contribution to journalArticle

  24. Age but not Philadelphia positivity impairs outcome in older/elderly patients with acute lymphoblastic leukemia in Sweden

    Kozlowski, P., Lennmyr, E., Ahlberg, L., Bernell, P., Hulegårdh, E., Karbach, H., Karlsson, K., Tomaszewska-Toporska, B., Åström, M., Hallböök, H. & the Swedish Adult Acute Lymphoblastic Leukemia Group (SVALL), 2017 Aug 1, In : European Journal of Haematology. 99, 2, p. 141-149 9 p.

    Research output: Contribution to journalArticle

  25. A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

    Speedy, H. E., Di Bernardo, M. C., Sava, G. P., Dyer, M. J. S., Holroyd, A., Wang, Y., Sunter, N. J., Mansouri, L., Juliusson, G., Smedby, K. E., Roos, G., Jayne, S., Majid, A., Dearden, C., Hall, A. G., Mainou-Fowler, T., Jackson, G. H., Summerfield, G., Harris, R. J., Pettitt, A. R. & 9 othersAllsup, D. J., Bailey, J. R., Pratt, G., Pepper, C., Fegan, C., Rosenquist, R., Catovsky, D., Allan, J. M. & Houlston, R. S., 2014, In : Nature Genetics. 46, 1, p. 56

    Research output: Contribution to journalArticle

  26. A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1

    Charlotta Böiers, Richardson, S. E., Laycock, E., Zriwil, A., Turati, V. A., Brown, J., Wray, J. P., Wang, D., James, C., Herrero, J., Ewa Sitnicka, Stefan Karlsson, Smith, A. J. H., Jacobsen, S. E. W. & Tariq Enver, 2018 Feb 5, In : Developmental Cell. 44, 3, p. 362-377.e7

    Research output: Contribution to journalArticle

  27. Allogeneic haematopoietic stem-cell transplantation with reduced intensity conditioning for advanced stage Hodgkin's lymphoma in Sweden: high incidence of post transplant lymphoproliferative disorder

    Johansson, J-E., Remberger, M., Lazarevic, V., Hallbook, H., Wahlin, A., Kimby, E., Gunnar Juliusson, Omar, H. & Hagglund, H., 2011, In : Bone Marrow Transplantation. 46, 6, p. 870-875

    Research output: Contribution to journalArticle

  28. Allogeneic hematopoietic stem cell transplant with reduced-intensity conditioning for chronic lymphocytic leukemia in Sweden: does donor T-cell engraftment 3 months after transplant predict survival?

    Machaczka, M., Johansson, J-E., Remberger, M., Hallbook, H., Malm, C., Lazarevic, V., Wahlin, A., Omar, H., Gunnar Juliusson, Kimby, E. & Hagglund, H., 2012, In : Leukemia & Lymphoma. 53, 9, p. 1699-1705

    Research output: Contribution to journalArticle

  29. Altered alpha-defensin 5 expression in cervical squamocolumnar junction: implication in the formation of a viral/tumour-permissive microenvironment

    Hubert, P., Herman, L., Roncarati, P., Maillard, C., Renoux, V., Demoulin, S., Erpicum, C., Foidart, J-M., Boniver, J., Noel, A., Delvenne, P. & Herfs, M., 2014, In : Journal of Pathology. 234, 4, p. 464-477

    Research output: Contribution to journalArticle

  30. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

    Martin Wahlestedt, Norddahl, G., Sten, G., Amol Ugale, Micha Frisk, M-A., Mattsson, R., Tomas Deierborg, Mikael Sigvardsson & David Bryder, 2013, In : Blood. 121, 21, p. 4257-4264

    Research output: Contribution to journalArticle

  31. A new approach for ratiometric in vivo calcium imaging of microglia

    Brawek, B., Liang, Y., Savitska, D., Li, K., Fomin-Thunemann, N., Kovalchuk, Y., Zirdum, E., Johan Jakobsson & Garaschuk, O., 2017 Dec 1, In : Scientific Reports. 7, 1, 6030.

    Research output: Contribution to journalArticle

  32. A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, J., Aurélie Baudet, Abelechian, S., Bonderup, K., d'Altri, T., Porse, B., Brakebusch, C., Gunnar Juliusson & Cammenga, J., 2018, In : Genesis. 56, 9, e23238.

    Research output: Contribution to journalArticle

  33. An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: a multi-center study of 381 patients

    Nahi, H., Hägglund, H., Ahlgren, T., Bernell, P., Hardling, M., Karlsson, K., Lazarevic, V. L., Linderholm, M., Smedmyr, B., Aström, M. & Hallböök, H., 2008 Nov, In : Haematologica. 93, 11, p. 1734-8 5 p.

    Research output: Contribution to journalArticle

  34. An open-label phase I dose-finding study of APR-246 in hematological malignancies

    Deneberg, S., Cherif, H., Lazarevic, V. & G Juliusson, 2016 Jul 16, In : Blood Cancer Journal. 6, 7, p. e447

    Research output: Contribution to journalArticle

  35. A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis

    Brinch, M. A., Bzorek, M., Bondo, H., Zetterberg, E., Weis, B. O., Hasselbalch, H. C., Stefan Scheding & Ralfkiaer, E., 2011, In : APMIS. 119, p. 3-4

    Research output: Contribution to journalPublished meeting abstract

  36. A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis.

    Madelung, A., Bzorek, M., Bondo, H., Zetterberg, E., Bjerrum, O. W., Hasselbalch, H. C., Stefan Scheding & Ralfkiaer, E., 2012, In : Histopathology. 60, 4, p. 554-560

    Research output: Contribution to journalArticle

  37. A Novel Immunohistochemical Sequential Multi Labelling and Erasing Technique Enables Epitope Characterization of Bone Marrow Pericytes In Primary Myelofibrosis

    Madelung, A. B., Bzorek, M., Bondo, H., Zetterberg, E. M. K., Bjerrum, O. W., Hasselbalch, H. C., Stefan Scheding & Ralfkiaer, E., 2010, In : Blood. 116, 21, p. 1672-1673

    Research output: Contribution to journalPublished meeting abstract

  38. A novel Lin-CD34+CD38-integrin α2- bipotential megakaryocyte-erythrocyte progenitor population in human bone marrow.

    Wong, W. M., Dolinska, M., Mikael Sigvardsson, Marja Ekblom & Qian, H., 2015, In : Leukemia. 30, p. 1399-1402

    Research output: Contribution to journalArticle

  39. Antagonistic Human FcγRIIB (CD32B) Antibodies Have Anti-Tumor Activity and Overcome Resistance to Antibody Therapy In Vivo.

    Roghanian, A., Teige, I., Mårtensson, L., Cox, K. L., Kovacek, M., Ljungars, A., Mattson, J., Sundberg, A., Vaughan, A. T., Shah, V., Smyth, N. R., Sheth, B., Chan, H. T. C., Li, Z-C., Williams, E. L., Manfredi, G., Oldham, R. J., Mockridge, C. I., James, S. A., Dahal, L. N. & 12 othersHussain, K., Björn Nilsson, Verbeek, J. S., Gunnar Juliusson, Markus Hansson, Mats Jerkeman, Johnson, P. W. M., Davies, A., Beers, S. A., Glennie, M. J., Frendéus, B. & Cragg, M. S., 2015, In : Cancer Cell. 27, 4, p. 473-488

    Research output: Contribution to journalArticle

  40. Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

    Helena Ågerstam, Christine Karlsson, Hansen, N., Carl Sandén, Askmyr, M., Sofia von Palffy, Högberg, C., Rissler, M., Wunderlich, M., Gunnar Juliusson, Johan Richter, Sjöström, K., Bhatia, R., Mulloy, J. C., Marcus Järås & Thoas Fioretos, 2015, In : Proceedings of the National Academy of Sciences. 112, 34, p. 10786-10791

    Research output: Contribution to journalArticle

  41. Antibody-encoding repertoires of bone marrow and peripheral blood-a focus on IgE

    Levin, M., Fredrik Levander, Palmason, R., Greiff, L. & Mats Ohlin, 2017, In : Journal of Allergy and Clinical Immunology. 139, 3, p. 1026-1030

    Research output: Contribution to journalLetter

  42. Anti-endotoxic and antibacterial effects of a dermal substitute coated with host defense peptides.

    Kasetty, G., Kalle, M., Mörgelin, M., Brune, J. C. & Artur Schmidtchen, 2015, In : Biomaterials. 53, p. 415-425

    Research output: Contribution to journalArticle

  43. A pragmatic approach to dealing with fingolimod-related lynnphopaenia in Europe

    Giovannonin, G., de Jong, B., Derfuss, T., Izquierdo, G., Mazibrada, G., Molyneux, P., Nicholas, R., Overell, J., Ziemssen, T. & Gunnar Juliusson, 2015, In : Multiple Sclerosis and Related Disorders. 4, 1, p. 83-84

    Research output: Contribution to journalLetter

  44. A Randomised Placebo Controlled Study With Melphalan/Prednisone Vs Melphalan/Prednisone/Thalidomide: Quality Of Life And Toxicity

    Gulbrandsen, N., Waage, A., Gimsing, P., Ingemar Turesson, Gunnar Juliusson, Abildgaard, N., Bjorkstrand, B., Carlson, K., Dahl, I. M., Forsberg, K., Knudsen, L. M., Nielsen, J. L., Mellqvist, U. H., Nesthus, I., Strandberg, M., Wisloff, F. & Fayers, P., 2008, In : Haematologica-The Hematology Journal. 93, p. 0209

    Research output: Contribution to journalPublished meeting abstract

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