Stem Cell Center

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  1. Defining 'stemness': Notch and Wnt join forces?

    Jacobsen, S. E. W., 2005, In : Nature Immunology. 6, 3, p. 234-236

    Research output: Contribution to journalLetter

  2. Definition of Genetic Events Directing the Development of Distinct Types of Brain Tumors from Postnatal Neural Stem/Progenitor Cells.

    Hertwig, F., Meyer, K., Sebastian Braun, Ek, S., Spang, R., Pfenninger, C., Isabella Artner, Prost, G., Chen, X., Biegel, J. A., Judkins, A. R., Elisabet Englund & Nuber, U., 2012, In : Cancer Research. 72, 13, p. 3381-3392

    Research output: Contribution to journalArticle

  3. Definitive endoderm: a key step in coaxing human embryonic stem cells into transplantable beta-cells.

    Semb, H., 2008, In : Biochemical Society Transactions. 36, Pt 3, p. 272-275

    Research output: Contribution to journalArticle

  4. Delineating the cellular pathways of hematopoietic lineage commitment.

    Luc, S., Buza-Vidas, N. & Jacobsen, S. E. W., 2008, In : Seminars in Immunology. 20, p. 213-220

    Research output: Contribution to journalArticle

  5. Delineation of the earliest lineage commitment steps of haematopoietic stem cells: new developments, controversies and major challenges

    Buza-Vidas, N., Luc, S. & Jacobsen, S. E. W., 2007, In : Current Opinion in Hematology. 14, 4, p. 315-321

    Research output: Contribution to journalArticle

  6. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

    Hyrenius-Wittsten, A., Pilheden, M., Sturesson, H., Hansson, J., Walsh, M. P., Song, G., Kazi, J. U., Liu, J., Ramakrishan, R., Garcia-Ruiz, C., Nance, S., Gupta, P., Zhang, J., Rönnstrand, L., Hultquist, A., Downing, J. R., Lindkvist-Petersson, K., Paulsson, K., Järås, M., Gruber, T. A. & 2 others, Ma, J. & Anna K. Hagström-Andersson, 2018 Dec 1, In : Nature Communications. 9, 1, 1770.

    Research output: Contribution to journalArticle

  7. Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia.

    Karrman, K., Anna Andersson, Björgvinsdottir, H., Strömbeck, B., Lassen, C., Olofsson, T., Nguyen-Khac, F., Berger, R., Bernard, O., Thoas Fioretos & Bertil Johansson, 2006, In : European Journal of Haematology. 77, 1, p. 27-34

    Research output: Contribution to journalArticle

  8. Derivation of a xeno-free human ES cell line.

    Ellerström, C., Strehl, R., Moya, K., Andersson, K., Bergh, C., Lundin, K., Hyllner, J. & Semb, H., 2006, In : Stem Cells. 24, 10, p. 2170-2176

    Research output: Contribution to journalArticle

  9. Desmosomes and cytoskeletal architecture in epithelial differentiation: cell type-specific plaque components and intermediate filament anchorage

    Schmidt, A., Heid, H. W., Schafer, S., Nuber, U., Zimbelmann, R. & Franke, W. W., 1994, In : European Journal of Cell Biology. 65, 2, p. 229-245

    Research output: Contribution to journalArticle

  10. Desmosomes--dual junctional principles of intra- and supracellular order in epithelial differentiation and tissue formation

    Franke, W. W., Nuber, U., Schmidt, A. & Schafer, S., 1994, In : Verhandlungen der Deutschen Gesellschaft fur Pathologie. 78, p. 8-14

    Research output: Contribution to journalArticle

  11. Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.

    Miyake, K., Johan Flygare, Kiefer, T., Utsugisawa, T., Johan Richter, Ma, Z., Wiznerowicz, M., Trono, D. & Stefan Karlsson, 2005, In : Molecular Therapy. 11, 4, p. 627-637

    Research output: Contribution to journalArticle

  12. Development of Humanized Ossicles: Bridging the Hematopoietic Gap

    Steven J. Dupard, Ani Grigoryan, Farhat, S., Coutu, D. L. & Paul E. Bourgine, 2020 Mar 3, In : Trends in Molecular Medicine.

    Research output: Contribution to journalReview article

  13. Differential Expression of Granulopoiesis Related Genes in Neutrophil Subsets Distinguished by Membrane Expression of CD177.

    Hu, N., Mora-Jensen, H., Theilgaard-Moench, K., Doornbos-van der Meer, B., Huitema, M. G., Stegeman, C. A., Heeringa, P., Kallenberg, C. G. M. & Westra, J., 2014, In : PLoS ONE. 9, 6, e99671.

    Research output: Contribution to journalArticle

  14. Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2

    Buitenhuis, M., van Deutekom, H. W. M., Verhagen, L. P., Anders Castor, Jacobsen, S. E. W., Lammers, J. W. J., Koenderman, L. & Coffer, P. J., 2005, In : Blood. 105, 11, p. 4272-4281

    Research output: Contribution to journalArticle

  15. Diode laser spectroscopy for non-invasive monitoring of oxygen in the lungs of newborn infants.

    Emilie Krite Svanberg, Lundin, P., Larsson, M., Jonas Åkeson, Katarina Svanberg, Svanberg, S., Andersson-Engels, S. & Vineta Fellman, 2016, In : Pediatric Research. 79, p. 621-628

    Research output: Contribution to journalArticle

  16. Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

    Pulecio, J., Alejo-Valle, O., Sandra Capellera-Garcia, Vitaloni, M., Rio, P., Mejía-Ramírez, E., Caserta, I., Bueren, J. A., Johan Flygare & Raya, A., 2016 Oct 11, In : Cell Reports. 17, 3, p. 671-683 13 p.

    Research output: Contribution to journalArticle

  17. Direct reprogramming into interneurons: potential for brain repair

    Pereira, M., Marcella Birtele & Daniella Rylander Ottosson, 2019, In : Cellular and Molecular Life Sciences. 76, 20, p. 3953-3967

    Research output: Contribution to journalReview article

  18. Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.

    Cheng, M., NozadCharoudeh, H., Brodin, P., Tang, Y., Lakshmikanth, T., Höglund, P., Jacobsen, S. E. W. & Ewa Sitnicka Quinn, 2009, In : Journal of immunology (Baltimore, Md. : 1950). 182, 3, p. 1460-1468

    Research output: Contribution to journalArticle

  19. Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors

    Marincevic, M., Mansouri, M., Kanduri, M., Isaksson, A., Goransson, H., Smedby, K. E., Jurlander, J., Gunnar Juliusson, Davi, F., Stamatopoulos, K. & Rosenquist, R., 2010, In : Haematologica. 95, 12, p. 2072-2079

    Research output: Contribution to journalArticle

  20. Distinct gene expression signatures in human embryonic stem cells differentiated towards definitive endoderm at single-cell level.

    Norrman, K., Strömbeck, A., Semb, H. & Ståhlberg, A., 2012, In : Methods.

    Research output: Contribution to journalArticle

  21. Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia.

    Anders Castor, Nilsson, L., Åstrand-Grundström, I., Buitenhuis, M., Ramirez, C., Anderson, K., Strömbeck, B., Garwicz, S., Békássy, A., Schmiegelow, K., Lausen, B., Hokland, P., Lehmann, S., Gunnar Juliusson, Bertil Johansson & Jacobsen, S. E. W., 2005, In : Nature Medicine. 11, 6, p. 630-637

    Research output: Contribution to journalArticle

  22. Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells

    Ramsfjell, V., David Bryder, Björgvinsdottir, H., Kornfält, S., Nilsson, L., Borge, O. J. & Jacobsen, S. E. W., 1999, In : Blood. 94, 12, p. 4093-4102

    Research output: Contribution to journalArticle

  23. Distinct roles of integrins alpha 6 and alpha 4 in fetal liver hematopoietic stem and progenitor cell homing

    Qian, H., Georges-Labouesse, E., Nyström, A., Domogatskaya, A., Tryggvason, K., Jacobsen, S. E. W. & Marja Ekblom, 2008, In : Cell Research. 18

    Research output: Contribution to journalPublished meeting abstract

  24. Distinct roles of integrins {alpha}6 and {alpha}4 in homing of fetal liver hematopoietic stem and progenitor cells.

    Qian, H., Georges-Labouesse, E., Nyström, A., Domogatskaya, A., Tryggvason, K., Jacobsen, S. E. W. & Marja Ekblom, 2007, In : Blood. 110, 7, p. 2399-2407

    Research output: Contribution to journalArticle

  25. Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles

    Kanduri, M., Marincevic, M., Halldorsdottir, A. M., Mansouri, L., Junevik, K., Ntoufa, S., Kultima, H. G., Isaksson, A., Gunnar Juliusson, Andersson, P-O., Hans Ehrencrona, Stamatopoulos, K. & Rosenquist, R., 2012, In : Epigenetics. 7, 12, p. 1435-1442

    Research output: Contribution to journalArticle

  26. DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis.

    Svensson, E., Eriksson, H., Gekas, C., Olofsson, T., Johan Richter & Urban Gullberg, 2005, In : Experimental Cell Research. 308, 1, p. 211-221

    Research output: Contribution to journalArticle

  27. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

    Broeske, A-M., Vockentanz, L., Kharazi, S., Huska, M. R., Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., Nerlov, C., Leutz, A., Andrade-Navarro, M. A., Jacobsen, S. E. W. & Rosenbauer, F., 2009, In : Nature Genetics. 41, 11, p. 1207-U69

    Research output: Contribution to journalArticle

  28. DNA Microarrays

    Nuber, U. (ed.), 2005, Taylor & Francis. 299 p.

    Research output: Book/ReportAnthology (editor)

  29. Does Low-Molecular-Weight Heparin Influence the Antimyeloma Effects of Thalidomide? A Retrospective Analysis of Data from the GIMEMA, Nordic and Turkish Myeloma Study Groups

    Beksac, M., Waage, A., Bringhen, S., Kristinsson, S. Y., Sucak, G. T., Gimsing, P., Lupparelli, G., Firatli-Tuglular, T., Gunnar Juliusson, Ingemar Turesson & Palumbo, A., 2015, In : Acta Haematologica. 133, 4, p. 372-380

    Research output: Contribution to journalArticle

  30. Donor lymphocyte infusion as therapy for persistent pure red cell aplasia following major ABO-incompatible stem cell transplantation

    Lübking, A., Winqvist, I. & Lenhoff, S., 2009, In : Bone Marrow Transplantation. 43, p. S373-S373

    Research output: Contribution to journalPublished meeting abstract

  31. Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

    Göran Karlsson, Mikael Sigvardsson & Charlotta Böiers, 2017 Dec 15, In : EMBO Journal. 36, 24, p. 3552-3554 3 p.

    Research output: Contribution to journalArticle

  32. Down-Regulation of CEBPA Expression Has a Stronger Impact on Myeloid Differentiation in Human Versus Mouse Cells: Mechanistic Implications for CEBPA Mutations in AML.

    Iwansk, G. B., Niebuhr, B., Taeger, M., Roscher, S., Stocking, C. & Cammenga, J., 2008, In : Blood. 112, 11, p. 493-493

    Research output: Contribution to journalPublished meeting abstract

  33. Downregulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.

    Luc, S., Anderson, K., Kharazi, S., Buza-Vidas, N., Charlotta Böiers, Christina Jensen, Ma, Z., Wittmann, L. & Jacobsen, S. E. W., 2008, In : Blood. 111, 7, p. 3424-3434

    Research output: Contribution to journalArticle

  34. Downstream effects of master regulators in two brain diseases.

    Sebastian Braun, 2012, 105 p.

    Research output: ThesisDoctoral Thesis (compilation)

  35. Doxorubicin pharmacokinetics in children with acute lymphoblastic leukemia

    Frost, B. M., Eksborg, S., Bjork, O., Abrahamsson, J., Behrendtz, M., Anders Castor, Forestier, E. & Lonnerholm, G., 2001, In : Leukemia. 15, 3, p. 498

    Research output: Contribution to journalPublished meeting abstract

  36. Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

    Ota, C., Ng-Blichfeldt, J-P., Korfei, M., Hani N. Alsafadi, Lehmann, M., Skronska-Wasek, W., Martina M. De Santis, Guenther, A., Darcy Wagner & Königshoff, M., 2018 Aug 28, In : Scientific Reports. 8, 12983.

    Research output: Contribution to journalArticle

  37. Dynamics of Cell Generation and Turnover in the Human Heart.

    Bergmann, O., Zdunek, S., Felker, A., Salehpour, M., Alkass, K., Bernard, S., Sjostrom, S. L., Szewczykowska, M., Jackowska, T., Dos Remedios, C., Torsten Malm, Andrä, M., Jashari, R., Nyengaard, J. R., Possnert, G., Jovinge, S., Druid, H. & Frisén, J., 2015, In : Cell. 161, 7, p. 1566-1575

    Research output: Contribution to journalArticle

  38. E2-2 Dependent Plasmacytoid Dendritic Cells Control Autoimmune Diabetes.

    Hansen, L., Anja Schmidt-Christensen, Gupta, S., Fransén Pettersson, N., Hannibal, T., Reizis, B., Santamaria, P. & Dan Holmberg, 2015 Dec 1, In : PLoS ONE. 10, 12, e0144090.

    Research output: Contribution to journalArticle

  39. Early B-Cell Factor, E2A, and Pax-5 Cooperate To Activate the Early B Cell-Specific mb-1 Promoter.

    Mikael Sigvardsson, Clark, D. R., Fitzsimmons, D., Doyle, M., Åkerblad, P., Breslin, T., Bilke, S., Li, R., Yeamans, C., Zhang, G. & Hagman, J., 2002, In : Molecular and Cellular Biology. 22, 24, p. 8539-8551

    Research output: Contribution to journalArticle

  40. Early B-cell factor (o/e-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation.

    Åkerblad, P., Lind, U., Liberg, D., Bamberg, K. & Mikael Sigvardsson, 2002, In : Molecular and Cellular Biology. 22, 22, p. 8015-8025

    Research output: Contribution to journalArticle

  41. Early Cellular Pathways of Mouse Natural Killer Cell Development.

    Ewa Sitnicka Quinn, 2011, In : Journal of Innate Immunity. 3, 4, p. 329-336

    Research output: Contribution to journalReview article

  42. Early response predicts thalidomide efficiency in patients with advanced multiple myeloma

    Waage, A., Gimsing, P., Juliusson, G., Ingemar Turesson, Gulbrandsen, N., Eriksson, T., Hjorth, M., Nielsen, JL., Lenhoff, S., Westin, J. & Wisloff, F., 2004, In : British Journal of Haematology. 125, 2, p. 149-155

    Research output: Contribution to journalArticle

  43. EBF1 is essential for B-Lineage priming and establishment of a transcription factor network in common lymphoid progenitors

    Zandi, S., Månsson, R., Tsapogas, P., Zetterblad, J., David Bryder & Mikael Sigvardsson, 2008, In : Journal of Immunology. 181, 5, p. 3364-3372

    Research output: Contribution to journalArticle

  44. Ectopic expression of PAX5 promotes self renewal of bi-phenotypic myeloid progenitors co-expressing myeloid and B-cell lineage associated genes.

    Anderson, K., Rusterholz, C., Månsson, R., Christina Jensen, Karl Bacos, Zandi, S., Sasaki, Y., Nerlov, C., Mikael Sigvardsson & Jacobsen, S. E. W., 2007, In : Blood. 109, Jan 11, p. 3697-3705

    Research output: Contribution to journalArticle

  45. Effective CD3 T-cell depletion using the CliniMacs (R) System to produce peripheral blood progenitor cell products for haploidentical transplantation in 23 children and adults: the updated Lund experience

    Dykes, J., Toporski, J., Turkiewicz, D., Gunnar Juliusson, Békássy, A., Lenhoff, S., Lindmark, A. & Stefan Scheding, 2010, In : Bone Marrow Transplantation. 45, Suppl.2, p. S325-S325

    Research output: Contribution to journalPublished meeting abstract

  46. Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2+ Human Pancreatic Progenitors

    Ameri, J., Borup, R., Prawiro, C., Ramond, C., Schachter, K. A., Scharfmann, R. & Semb, H., 2017 Apr 4, In : Cell Reports. 19, 1, p. 36-49 14 p.

    Research output: Contribution to journalArticle

  47. Efficient Purification of CD4+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Affinity Bead Acoustophoresis

    Andreas Lenshof, Jamal, A., Dykes, J., Anke Urbansky, Åstrand-Grundström, I., Thomas Laurell & Stefan Scheding, 2014, In : Cytometry Part A. 85A, 11, p. 933-941

    Research output: Contribution to journalArticle

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