Stem Cell Center

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  1. High relapse rate of T cell acute lymphoblastic leukemia in adults treated with Hyper-CVAD chemotherapy in Sweden

    Kozlowski, P., Astrom, M., Ahlberg, L., Bernell, P., Hulegardh, E., Hagglund, H., Karlsson, K., Markuszewska-Kuczymska, A., Tomaszewska-Toporska, B., Smedmyr, B., Amini, R-M. & Hallbook, H., 2014, In : European Journal of Haematology. 92, 5, p. 377-381

    Research output: Contribution to journalArticle

  2. High Resolution Screening of Copy-Number Alterations in Chronic Lymphocytic Leukemia Using Affymetrix 250K SNP-Arrays Reveals a Higher Complexity of Genomic Alterations in Patients with Unmutated IGHV Genes

    Rebeqa Gunnarsson, Isaksson, A., Goeransson, H., Mansouri, L., Jansson, M., Cahill, N., Smedby, K. E., Jurlander, J., Gunnar Juliusson & Rosenquist, R., 2008, In : Blood. 112, 11, p. 1074-1074

    Research output: Contribution to journalPublished meeting abstract

  3. HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.

    Mattias Magnusson, Brun, A., Miyake, N., Jonas Larsson, Mats Ehinger, Björnsson, J. M., Wutz, A., Mikael Sigvardsson & Stefan Karlsson, 2007, In : Blood. 109, 9, p. 3687-3696

    Research output: Contribution to journalArticle

  4. Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes

    Rostami, J., Holmqvist, S., Lindström, V., Sigvardson, J., Westermark, G. T., Ingelsson, M., Bergström, J., Laurent Roybon & Erlandsson, A., 2017 Dec 6, In : Journal of Neuroscience. 37, 49, p. 11835-11853 19 p.

    Research output: Contribution to journalArticle

  5. Human blastocysts for the development of embryonic stem cells

    Sjogren, A., Hardarson, T., Andersson, K., Caisander, G., Lundquist, M., Wikland, M., Semb, H. & Hamberger, L., 2004, In : Reproductive BioMedicine Online. 9, 3, p. 326-329

    Research output: Contribution to journalArticle

  6. Human Embryonic Stem Cell Derived Mesenchymal Stroma Cells (hES-MSC) Share Basic Properties with Bone Marrow MSC, They Have Potent Stroma Support Capacities but Lack Immune Modulatory Function Implications for off the Shelf ES MSC Therapies

    Li, O., Tormin, A., Brune, J. C., Sundberg, B., Hyllner, J., Le Blanc, K. & Stefan Scheding, 2010, In : Blood. 116, 21, p. 1578-1578

    Research output: Contribution to journalPublished meeting abstract

  7. Human Embryonic Stem Cells - Constitutive Gene Expression and Differentiation Towards Definitive Endoderm and Posterior Foregut Endoderm

    Norrman, K., 2011, Stem Cells and Pancreas Developmental Biology, Dept of Laboratory Medicine. 123 p.

    Research output: ThesisDoctoral Thesis (compilation)

  8. Human embryonic stem cells: origin, properties and applications.

    Semb, H., 2005, In : APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 113, 11-12, p. 743-750

    Research output: Contribution to journalArticle

  9. Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.

    Grealish, S., Diguet, E., Agnete Kirkeby, Mattsson, B., Andreas Heuer, Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Anders Björklund & Malin Parmar, 2014, In : Cell Stem Cell. 15, 5, p. 653-665

    Research output: Contribution to journalArticle

  10. Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.

    Dybedal, I., Yang, L., David Bryder, Åstrand-Grundström, I., Karin Leandersson & Jacobsen, S. E. W., 2003, In : Blood. 102, 1, p. 118-126

    Research output: Contribution to journalArticle

  11. Hypo, Hyper, or Combo: New paradigm for treatment of acute myeloid leukemia in older people

    Gunnar Juliusson, Höglund, M. & Lehmann, S., 2020, In : Haematologica. 105, 2, p. 249-251

    Research output: Contribution to journalReview article

  12. Hypoxia mediates low cell-cycle activity and increases the proportion of long-term reconstituting hematopoietic stem cells during in vitro culture

    Eliasson, P., Rehn, M., Hammar, P., Larsson, P., Sirenko, O., Flippin, L. A., Cammenga, J. & Jonsson, J-I., 2010, In : Experimental Hematology. 38, 4, p. 301-310

    Research output: Contribution to journalArticle

  13. Identification and Characterization of Stem Cells in Preleukemia and Leukemia

    Nilsson, L., 2004, Lars Nilsson, BMC B10, KLinikgatan 26, S-221 84 Lund, Sweden,. 200 p.

    Research output: ThesisDoctoral Thesis (compilation)

  14. Identification of a NK/T cell restricted progenitor in adult bone marrow contributing to bone marrow and thymic-dependent NK cells.

    NozadCharoudeh, H., Tang, Y-J., Cheng, M., Corrado Cilio, Jacobsen, S. E. W. & Ewa Sitnicka Quinn, 2010, In : Blood. 116, 2, p. 183-192

    Research output: Contribution to journalArticle

  15. Identification of Flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential: A revised road map for adult blood lineage commitment

    Adolfsson, J., Månsson, R., Buza-Vidas, N., Anne Hultquist, Liuba, K., Christina Jensen, David Bryder, Yang, L., Borge, OJ., Thorén, L., Anderson, K., Ewa Sitnicka Quinn, Sasaki, Y., Mikael Sigvardsson & Jacobsen, S. E. W., 2005, In : Cell. 121, 2, p. 295-306

    Research output: Contribution to journalArticle

  16. Identification of Lin-Sca1+kit+CD34+Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated recipients.

    Yang, L., David Bryder, Adolfsson, J., Nygren, J., Månsson, R., Mikael Sigvardsson & Jacobsen, S. E. W., 2005, In : Blood. 105, 7, p. 2717-2723

    Research output: Contribution to journalArticle

  17. IFN-{gamma} Negatively Modulates Self-Renewal of Repopulating Human Hemopoietic Stem Cells.

    Yang, L., Dybedal, I., David Bryder, Nilsson, L., Ewa Sitnicka Quinn, Sasaki, Y. & Jacobsen, S. E. W., 2005, In : Journal of Immunology. 174, 2, p. 752-757

    Research output: Contribution to journalArticle

  18. IGHV3-21 Gene Frequency in a Swedish Cohort of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

    Cahill, N., Sutton, L-A., Jansson, M., Murray, F., Mansouri, L., Gunnarsson, R., Ryan, F., Smedby, K. E., Geisler, C., Gunnar Juliusson & Rosenquist, R., 2012, In : Clinical Lymphoma, Myeloma & Leukemia. 12, 3, p. 201-206

    Research output: Contribution to journalArticle

  19. IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

    Helena Ågerstam, Hansen, N., Sofia von Palffy, Carl Sandén, Reckzeh, K., Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Askmyr, M., Högberg, C., Rissler, M., Porkka, K., Wadenvik, H., Mustjoki, S., Johan Richter, Marcus Järås & Thoas Fioretos, 2016 Dec 8, In : Blood. 128, 23, p. 2683-2693

    Research output: Contribution to journalArticle

  20. Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis.

    Shi, C., Zhao, X., Lagergren, A., Mikael Sigvardsson, Wang, X. & Roland Andersson, 2006, In : Scandinavian Journal of Gastroenterology. 41, 4, p. 472-480

    Research output: Contribution to journalArticle

  21. Immunophenotypical characterization of human neutrophil differentiation

    Mora-Jensen, H., Jendholm, J., Fossum, A., Porse, B., Borregaad, N. & Theilgaard-Moench, K., 2011, In : Journal of Leukocyte Biology. 90, 3, p. 629-634

    Research output: Contribution to journalArticle

  22. Impact of age on survival after intensive therapy for multiple myeloma: a population-based study by the Nordic Myeloma Study Group.

    Lenhoff, S., Hjorth, M., Westin, J., Brinch, L., Backstrom, B., Carlson, K., Christiansen, I., Dahl, I. M., Gimsing, P., Hammerstrom, J., Johnsen, H. E., Juliusson, G., Linder, O., Mellqvist, U-H., Nesthus, I., Nielsen, J. L., Tangen, J. M. & Turesson, I., 2006, In : British Journal of Haematology. 133, 4, p. 389-396

    Research output: Contribution to journalArticle

  23. Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

    Kharazi, S., Mead, A. J., Mansour, A., Anne Hultquist, Charlotta Böiers, Luc, S., Buza-Vidas, N., Ma, Z., Ferry, H., Atkinson, D., Reckzeh, K., Masson, K., Cammenga, J., Lars Rönnstrand, Arai, F., Suda, T., Nerlov, C., Ewa Sitnicka Quinn & Jacobsen, S. E. W., 2011, In : Blood. 118, 13, p. 3613-3621

    Research output: Contribution to journalArticle

  24. Impact of growth factors in the regulation of apoptosis in low-risk myelodysplastic syndromes.

    Tehranchi, R., 2006, In : Medical Oncology. 23, 1, p. 37-49

    Research output: Contribution to journalReview article

  25. Impact of low copy repeats on the generation of balanced and unbalanced chromosomal aberrations in mental retardation

    Erdogan, F., Chen, W., Kirchhoff, M., Kalscheuer, V. M., Hultschig, C., Muller, I., Schulz, R., Menzel, C., Bryndorf, T., Ropers, H-H. & Ullmann, R., 2006, In : Cytogenetic and Genome Research. 115, 3-4, p. 247-253

    Research output: Contribution to journalArticle

  26. Impaired Function of Hematopoietic Stem Cells with Abrogated Hypoxia Induced Expression of Vascular Endothelial Growth Factor

    Rehn, M., Reckzeh, K., Olsson, A., Håkan Axelson & Cammenga, J., 2008, In : Blood. 112, 11, p. 110-110

    Research output: Contribution to journalPublished meeting abstract

  27. Impaired Insulin Exocytosis in Neural Cell Adhesion Molecule(-/-) Mice Due to Defective Reorganization of the Submembrane F-Actin Network

    Olofsson, C. S., Hakansson, J., Salehi, A., Bengtsson, M., Galvanovskis, J., Partridge, C., Sörhede Winzell, M., Xiaojie Xian, Eliasson, L., Lundquist, I., Semb, H. & Rorsman, P., 2009, In : Endocrinology. 150, 7, p. 3067-3075

    Research output: Contribution to journalArticle

  28. Improved survival of men 50 to 75 years old with acute myeloid leukemia over a 20-year period

    Gunnar Juliusson, Oskar Hagberg, Lazarevic, V. L., Ölander, E., Antunovic, P., Cammenga, J., Wennström, L., Möllgård, L., Brune, M., Jädersten, M., Deneberg, S., Lehmann, S., Derolf, Å. R., Martin Höglund & Swedish AML Registry, 2019 Oct 31, In : Blood. 134, 18, p. 1558-1561 4 p.

    Research output: Contribution to journalLetter

  29. Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population-based study from the Swedish AML registry

    Lj Lazarevic, V., Aldana Rosso, Gunnar Juliusson, Antunovic, P., Derolf, Å. R., Deneberg, S., Möllgård, L., Uggla, B., Wennström, L., Wahlin, A., Höglund, M., Lehmann, S. & Bertil Johansson, 2017, In : European Journal of Haematology. 98, 5, p. 493-500

    Research output: Contribution to journalArticle

  30. Incidence and prognostic significance of karyotypic subgroups in older patients with acute myeloid leukemia: the Swedish population-based experience.

    Lazarevic, V., Hörstedt, A., Bertil Johansson, Antunovic, P., Billström, R., Derolf, A., Hulegårdh, E., Lehmann, S., Möllgård, L., Nilsson, C., Peterson, S., Stockelberg, D., Uggla, B., Wennström, L., Wahlin, A., Höglund, M. & Gunnar Juliusson, 2014, In : Blood Cancer Journal. 4, Feb 28, p. e188

    Research output: Contribution to journalArticle

  31. Incidence, characteristics, and outcome of solitary plasmacytoma and plasma cell leukemia. Population-based data from the Swedish Myeloma Register

    Nahi, H., Genell, A., Wålinder, G., Uttervall, K., Gunnar Juliusson, Karin, F., Markus Hansson, Svensson, R., Linder, O., Carlson, K., Björkstrand, B., Kristinsson, S. Y., Mellqvist, U-H., Blimark, C. & Ingemar Turesson, 2017 Sep, In : European Journal of Haematology. 99, 3, p. 216-222

    Research output: Contribution to journalArticle

  32. Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death

    Ajmone-Cat, M. A., Onori, A., Toselli, C., Stronati, E., Morlando, M., Bozzoni, I., Emanuela Monni, Zaal Kokaia, Lupo, G., Minghetti, L., Biagioni, S. & Cacci, E., 2019 Mar 14, In : Scientific Reports. 9, 1, 4572.

    Research output: Contribution to journalArticle

  33. Increased remissions from one course for intermediate-dose cytosine arabinoside and idarubicin in elderly acute myeloid leukaemia when combined with cladribine. A randomized population-based phase II study

    Gunnar Juliusson, Hoglund, M., Karlsson, K., Lofgren, C., Mollgard, L., Paul, C., Tidefelt, U. & Bjorkholm, M., 2003, In : British Journal of Haematology. 123, 5, p. 810-818

    Research output: Contribution to journalArticle

  34. Induction chemotherapy and post-remission imatinib therapy for de Novo BCR-ABL-positive AML

    Lazarevic, V., Golovleva, I., Nygren, I. & Wahlin, A., 2006 Jun, In : American Journal of Hematology. 81, 6, p. 470-1 2 p.

    Research output: Contribution to journalArticle

  35. Induction of ID2 expression by hypoxia-inducible factor-1: ARole in dedifferentiation of hypoxic neuroblastoma cells.

    Löfstedt, T., Annika Jögi, Mikael Sigvardsson, Gradin, K., Poellinger, L., Sven Påhlman & Håkan Axelson, 2004, In : Journal of Biological Chemistry. 279, 38, p. 39223-39231

    Research output: Contribution to journalArticle

  36. Inferior Overall Survival In Cll Patients With Tp53 Mutations And Mdm2 Snp309 Polymorphism

    Linderholm, R. H., Willander, K., Karlsson, K. & Soderkvist, P., 2008, In : Haematologica-The Hematology Journal. 93, p. 0529

    Research output: Contribution to journalPublished meeting abstract

  37. Inflammation and cholesterol

    Jan Nilsson, Ares, M., Lindholm, M., Nordin Fredrikson, G. & Jovinge, S., 2002, In : European Heart Journal Supplements. 4, Suppl A, p. A18-A25

    Research output: Contribution to journalArticle

  38. Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development

    Emma Smith, Akerblad, P., Kadesch, T., Håkan Axelson & Mikael Sigvardsson, 2005, In : Blood. 106, 6, p. 1995-2001

    Research output: Contribution to journalArticle

  39. Inhibition of p300/CBP by early B-cell factor

    Zhao, F., McCarrick-Walmsley, R., Åkerblad, P., Mikael Sigvardsson & Kadesch, T., 2003, In : Molecular and Cellular Biology. 23, 11, p. 3837-3846

    Research output: Contribution to journalArticle

  40. Inhibition of Tumor Necrosis Factor-{alpha} Reduces Atherosclerosis in Apolipoprotein E Knockout Mice.

    Brånén, L., Hovgaard, L., Nitulescu, M., Eva Bengtsson, Jan Nilsson & Jovinge, S., 2004, In : Arteriosclerosis, Thrombosis and Vascular Biology. 24, 11, p. 2137-2142

    Research output: Contribution to journalArticle

  41. Inhibitory effect on arterial injury-induced neointimal formation by adoptive B-cell transfer in Rag-1 knockout mice.

    Dimayuga, P., Cercek, B., Oguchi, S., Nordin Fredrikson, G., Yano, J., Shah, P. K., Jovinge, S. & Jan Nilsson, 2002, In : Arteriosclerosis, Thrombosis and Vascular Biology. 22, 4, p. 644-9

    Research output: Contribution to journalArticle

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