Stem Cell Center

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  1. 2015
  2. Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes

    Tarnawski, L., Xiaojie Xian, Monnerat, G., Macaulay, I. C., Malan, D., Borgman, A., Wu, S. M., Fleischmann, B. K. & Jovinge, S., 2015, In : PLoS ONE. 10, 8, e0135880.

    Research output: Contribution to journalArticle

  3. Maf transcription factors in beta cell function

    Ganic, E., 2015, Stem Cell Center, Lund University. 134 p.

    Research output: ThesisDoctoral Thesis (compilation)

  4. No evidence for higher risk of cancer in patients with multiple sclerosis taking cladribine.

    Pakpoor, J., Disanto, G., Altmann, D. R., Pavitt, S., Turner, B. P., Marta, M., Gunnar Juliusson, Baker, D., Chataway, J. & Schmierer, K., 2015, In : Neurology: Neuroimmunology and NeuroInflammation. 2, 6, p. e158

    Research output: Contribution to journalArticle

  5. Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

    Baliakas, P., Agathangelidis, A., Hadzidimitriou, A., Sutton, L-A., Minga, E., Tsanousa, A., Scarfò, L., Davis, Z., Yan, X-J., Shanafelt, T., Plevova, K., Sandberg, Y., Vojdeman, F. J., Boudjogra, M., Tzenou, T., Chatzouli, M., Chu, C. C., Veronese, S., Gardiner, A., Mansouri, L. & 28 othersSmedby, K. E., Pedersen, L. B., Moreno, D., Van Lom, K., Giudicelli, V., Francova, H. S., Nguyen-Khac, F., Panagiotidis, P., Gunnar Juliusson, Angelis, L., Anagnostopoulos, A., Lefranc, M-P., Facco, M., Trentin, L., Catherwood, M., Montillo, M., Geisler, C. H., Langerak, A. W., Pospisilova, S., Chiorazzi, N., Oscier, D., Jelinek, D. F., Darzentas, N., Belessi, C., Davi, F., Ghia, P., Rosenquist, R. & Stamatopoulos, K., 2015, In : Blood. 125, 5, p. 856-859

    Research output: Contribution to journalArticle

  6. Prognostic significance of high hyperdiploid and tri-/tetraploid adult acute myeloid leukemia.

    Lazarevic, V., Aldana Rosso, Gunnar Juliusson, Antunovic, P., Rangert-Derolf, Å., Lehmann, S., Möllgård, L., Uggla, B., Wennström, L., Wahlin, A., Höglund, M. & Bertil Johansson, 2015, In : American Journal of Hematology. 90, 9, p. 800-805

    Research output: Contribution to journalArticle

  7. Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

    Baliakas, P., Hadzidimitriou, A., Sutton, L-A., Rossi, D., Minga, E., Villamor, N., Larrayoz, M., Kminkova, J., Agathangelidis, A., Davis, Z., Tausch, E., Stalika, E., Kantorova, B., Mansouri, L., Scarfò, L., Cortese, D., Navrkalova, V., Rose-Zerilli, M. J. J., Smedby, K. E., Juliusson, G. & 14 othersAnagnostopoulos, A., Makris, A. M., Navarro, A., Delgado, J., Oscier, D., Belessi, C., Stilgenbauer, S., Ghia, P., Pospisilova, S., Gaidano, G., Campo, E., Strefford, J. C., Stamatopoulos, K. & Rosenquist, R., 2015, In : Leukemia. 29, 2, p. 329-336

    Research output: Contribution to journalArticle

  8. Regulation of advanced therapy medicinal products will affect the practice of haematopoietic SCT in the near future: a perspective from the EBMT cell-processing committee.

    Chabannon, C., Hildebrandt, M., Stefan Scheding, Humpe, A., Lowdell, M. & Slaper-Cortenbach, I., 2015, In : Bone Marrow Transplantation. 50, 3, p. 321-323

    Research output: Contribution to journalDebate/Note/Editorial

  9. Retinoic Acid regulates hematopoietic development from human pluripotent stem cells.

    Roger Rönn, Guibentif, C., Moraghebi, R., Chaves Guerrero, P., Saxena, S., Garcia, B. & Niels-Bjarne Woods, 2015, In : Stem Cell Reports. 4, 2, p. 269-281

    Research output: Contribution to journalArticle

  10. Satisfactory outcome after intensive chemotherapy with pragmatic use of minimal residual disease (MRD) monitoring in older patients with Philadelphia-negative B cell precursor acute lymphoblastic leukaemia: a Swedish registry-based study

    Bergfelt, E., Kozlowski, P., Ahlberg, L., Hulegardh, E., Hagglund, H., Karlsson, K., Markuszewska-Kuczymska, A., Tomaszewska-Toporska, B., Smedmyr, B., Astrom, M., Amini, R-M. & Hallbook, H., 2015, In : Medical Oncology. 32, 4, p. 135

    Research output: Contribution to journalArticle

  11. Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment.

    Olsson, A., Nakhlé, J., Sundstedt, A., Plas, P., Bauchet, A-L., Pierron, V., Bruetschy, L., Deronic, A., Törngren, M., Liberg, D., Schmidlin, F. & Tomas Leanderson, 2015, In : Journal for ImmunoTherapy of Cancer. 3, 53.

    Research output: Contribution to journalArticle

  12. The PDGFR Receptor Family

    Chitu, V., Caescu, C. I., Stanley, E. R., Lennartsson, J., Lars Rönnstrand & Heldin, C-H., 2015, Receptor Tyrosine Kinases: Family and Subfamilies. Wheeler, D. L. & Yarden, Y. (eds.). Springer, p. 373-538

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  13. The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation.

    Acosta, H., Iliev, D., Hooi Min Tan Grahn, Gouignard, N., Marco Maccarana, Griesbach, J., Herzmann, S., Sagha, M., Climent, M. & Edgar Pera, 2015, In : Development. 142, 6, p. 1146-1158

    Research output: Contribution to journalArticle

  14. Transgenic systems for unequivocal identification of cardiac myocyte nuclei and analysis of cardiomyocyte cell cycle status

    Raulf, A., Horder, H., Tarnawski, L., Geisen, C., Ottersbach, A., Roell, W., Jovinge, S., Fleischmann, B. K. & Hesse, M., 2015, In : Basic Research in Cardiology. 110, 3, p. 33

    Research output: Contribution to journalArticle

  15. UGT2B17 expression: a novel prognostic marker within IGHV-mutated chronic lymphocytic leukemia?

    Bhoi, S., Baliakas, P., Cortese, D., Mattsson, M., Engvall, M., Smedby, K. E., Gunnar Juliusson, Sutton, L-A. & Mansouri, L., 2015, In : Haematologica.

    Research output: Contribution to journalArticle

  16. Whole-mount in situ hybridization and immunohistochemistry in Xenopus embryos.

    Edgar Pera, Acosta, H., Gouignard, N. & Climent, M., 2015, In Situ Hybridization Methods. Hauptmannn, G. (ed.). 1 ed. New York: Humana Press, p. 151-167 (Neuromethods; vol. 99).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  17. Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation.

    Lübking, A., Vosberg, S., Konstandin, N. P., Dufour, A., Graf, A., Krebs, S., Blum, H., Weber, A., Lenhoff, S., Mats Ehinger, Spiekermann, K., Greif, P. A. & Cammenga, J., 2015, In : Leukemia Research Reports. 4, 2, p. 72-75

    Research output: Contribution to journalArticle

  18. β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4.

    Funa, N., Schachter, K., Lerdrup, M., Ekberg, J., Hess, K., Dietrich, N., Honoré, C., Hansen, K. & Semb, H., 2015, In : Cell Stem Cell. 16, 6, p. 639-652

    Research output: Contribution to journalArticle

  19. 2014
  20. Active signals, gradient formation and regional specificity in neural induction.

    Edgar Pera, Acosta, H., Gouignard, N., Climent, M. & Arregi, I., 2014, In : Experimental Cell Research. 321, 1, p. 25-31

    Research output: Contribution to journalReview article

  21. A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

    Speedy, H. E., Di Bernardo, M. C., Sava, G. P., Dyer, M. J. S., Holroyd, A., Wang, Y., Sunter, N. J., Mansouri, L., Juliusson, G., Smedby, K. E., Roos, G., Jayne, S., Majid, A., Dearden, C., Hall, A. G., Mainou-Fowler, T., Jackson, G. H., Summerfield, G., Harris, R. J., Pettitt, A. R. & 9 othersAllsup, D. J., Bailey, J. R., Pratt, G., Pepper, C., Fegan, C., Rosenquist, R., Catovsky, D., Allan, J. M. & Houlston, R. S., 2014, In : Nature Genetics. 46, 1, p. 56

    Research output: Contribution to journalArticle

  22. Altered alpha-defensin 5 expression in cervical squamocolumnar junction: implication in the formation of a viral/tumour-permissive microenvironment

    Hubert, P., Herman, L., Roncarati, P., Maillard, C., Renoux, V., Demoulin, S., Erpicum, C., Foidart, J-M., Boniver, J., Noel, A., Delvenne, P. & Herfs, M., 2014, In : Journal of Pathology. 234, 4, p. 464-477

    Research output: Contribution to journalArticle

  23. Bortezomib, melphalan, prednisone (VMP) versus melphalan, prednisone, thalidomide (MPT) in elderly newly diagnosed multiple myeloma patients: A retrospective case-matched study

    Morabito, F., Bringhen, S., Larocca, A., Wijermans, P., Victoria Mateos, M., Gimsing, P., Mazzone, C., Gottardi, D., Omede, P., Zweegman, S., Jose Lahuerta, J., Zambello, R., Musto, P., Magarotto, V., Schaafsma, M., Oriol, A., Juliusson, G., Cerrato, C., Catalano, L., Gentile, M. & 14 othersIsabel Turel, A., Liberati, A. M., Cavalli, M., Rossi, D., Passera, R., Rosso, S., Beksac, M., Cavo, M., Waage, A., San Miguel, J., Boccadoro, M., Sonneveld, P., Palumbo, A. & Offidani, M., 2014, In : American Journal of Hematology. 89, 4, p. 355-362

    Research output: Contribution to journalArticle

  24. Cardiac regeneration in vivo: Mending the heart from within?

    Bergmann, O. & Jovinge, S., 2014, In : Stem Cell Research. 13, 3, p. 523-531

    Research output: Contribution to journalReview article

  25. Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation.

    Kesavan, G., Lieven, O., Mamidi, A., Löf-Öhlin, Z., Johansson, J., Li, W-C., Lommel, S., Greiner, T. & Semb, H., 2014, In : Development. 141, 3, p. 685-696

    Research output: Contribution to journalArticle

  26. Cladribine prolongs progression-free survival and time to second treatment compared to fludarabine and high-dose chlorambucil in chronic lymphocytic

    Mulligan, S. P., Karlsson, K., Stromberg, M., Jonsson, V., Gill, D., Hammerstrom, J., Hertzberg, M., McLennan, R., Uggla, B., Norman, J., Wallvik, J., Sundstrom, G., Johansson, H., Brandberg, Y., Liliemark, J. & Gunnar Juliusson, 2014, In : Leukemia & Lymphoma. 55, 12, p. 2769-2777

    Research output: Contribution to journalArticle

  27. Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

    Baliakas, P., Hadzidimitriou, A., Sutton, L-A., Minga, E., Agathangelidis, A., Nichelatti, M., Tsanousa, A., Scarfo, L., Davis, Z., Yan, X-J., Shanafelt, T., Plevova, K., Sandberg, Y., Vojdeman, F. J., Boudjogra, M., Tzenou, T., Chatzouli, M., Chu, C. C., Veronese, S., Gardiner, A. & 28 othersMansouri, L., Smedby, K. E., Pedersen, L. B., van Lom, K., Giudicelli, V., Francova, H. S., Nguyen-Khac, F., Panagiotidis, P., Gunnar Juliusson, Angelis, L., Anagnostopoulos, A., Lefranc, M-P., Facco, M., Trentin, L., Catherwood, M., Montillo, M., Geisler, C. H., Langerak, A. W., Pospisilova, S., Chiorazzi, N., Oscier, D., Jelinek, D. F., Darzentas, N., Belessi, C., Davi, F., Rosenquist, R., Ghia, P. & Stamatopoulos, K., 2014, In : Lancet Haematology. 1, 2, p. E74-E84

    Research output: Contribution to journalArticle

  28. Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients

    Rapin, N., Bagger, F. O., Jendholm, J., Mora-Jensen, H., Krogh, A., Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, O., Theilgaard-Moench, K. & Porse, B. T., 2014, In : Blood. 123, 6, p. 894-904

    Research output: Contribution to journalArticle

  29. Differential Expression of Granulopoiesis Related Genes in Neutrophil Subsets Distinguished by Membrane Expression of CD177.

    Hu, N., Mora-Jensen, H., Theilgaard-Moench, K., Doornbos-van der Meer, B., Huitema, M. G., Stegeman, C. A., Heeringa, P., Kallenberg, C. G. M. & Westra, J., 2014, In : PLoS ONE. 9, 6, e99671.

    Research output: Contribution to journalArticle

  30. Efficient Purification of CD4+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Affinity Bead Acoustophoresis

    Andreas Lenshof, Jamal, A., Dykes, J., Anke Urbansky, Åstrand-Grundström, I., Thomas Laurell & Stefan Scheding, 2014, In : Cytometry Part A. 85A, 11, p. 933-941

    Research output: Contribution to journalArticle

  31. Feasibility of targeted next-generation sequencing of the TP53 and ATM genes in chronic lymphocytic leukemia

    Mansouri, L., Sutton, L-A., Ljungstrom, V., Sorqvist, E. F., Rebeqa Gunnarsson, Smedby, K. E., Gunnar Juliusson, Stamatopoulos, K., Nilsson, M. & Rosenquist, R., 2014, In : Leukemia. 28, 3, p. 694-696

    Research output: Contribution to journalLetter

  32. High relapse rate of T cell acute lymphoblastic leukemia in adults treated with Hyper-CVAD chemotherapy in Sweden

    Kozlowski, P., Astrom, M., Ahlberg, L., Bernell, P., Hulegardh, E., Hagglund, H., Karlsson, K., Markuszewska-Kuczymska, A., Tomaszewska-Toporska, B., Smedmyr, B., Amini, R-M. & Hallbook, H., 2014, In : European Journal of Haematology. 92, 5, p. 377-381

    Research output: Contribution to journalArticle

  33. Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.

    Shane Grealish, Diguet, E., Agnete Kirkeby, Mattsson, B., Andreas Heuer, Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Anders Björklund & Malin Parmar, 2014, In : Cell Stem Cell. 15, 5, p. 653-665

    Research output: Contribution to journalArticle

  34. Incidence and prognostic significance of karyotypic subgroups in older patients with acute myeloid leukemia: the Swedish population-based experience.

    Lazarevic, V., Hörstedt, A., Bertil Johansson, Antunovic, P., Billström, R., Derolf, A., Hulegårdh, E., Lehmann, S., Möllgård, L., Nilsson, C., Peterson, S., Stockelberg, D., Uggla, B., Wennström, L., Wahlin, A., Höglund, M. & Gunnar Juliusson, 2014, In : Blood Cancer Journal. 4, Feb 28, p. e188

    Research output: Contribution to journalArticle

  35. Low/Negative Expression of PDGFR-α Identifies the Candidate Primary Mesenchymal Stromal Cells in Adult Human Bone Marrow.

    Hongzhe Li, Roshanak Ghazanfari, Dimitra Zacharaki, Ditzel, N., Isern, J., Marja Ekblom, Méndez-Ferrer, S., Kassem, M. & Stefan Scheding, 2014, In : Stem Cell Reports. 3, 6, p. 965-974

    Research output: Contribution to journalArticle

  36. Minimizing risk of hypomethylating agent failure in patients with higher-risk MDS and practical management recommendations.

    Santini, V., Prebet, T., Fenaux, P., Gattermann, N., Nilsson, L., Pfeilstöcker, M., Vyas, P. & List, A. F., 2014, In : Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis. 38, 12, p. 1381-1391

    Research output: Contribution to journalReview article

  37. Musculoskeletal Pain in Patients With Chronic Myeloid Leukemia After Discontinuation of Imatinib: A Tyrosine Kinase Inhibitor Withdrawal Syndrome?

    Johan Richter, Söderlund, S., Lübking, A., Dreimane, A., Lotfi, K., Markevärn, B., Själander, A., Saussele, S., Olsson-Strömberg, U. & Stenke, L., 2014, In : Journal of Clinical Oncology. 32, 25, p. 2821-2823

    Research output: Contribution to journalLetter

  38. Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo.

    Woll, P. S., Kjällquist, U., Chowdhury, O., Doolittle, H., Wedge, D. C., Thongjuea, S., Erlandsson, R., Ngara, M., Anderson, K., Deng, Q., Mead, A. J., Stenson, L., Giustacchini, A., Duarte, S., Giannoulatou, E., Taylor, S., Karimi, M., Scharenberg, C., Mortera-Blanco, T., Macaulay, I. C. & 28 othersClark, S-A., Dybedal, I., Josefsen, D., Fenaux, P., Hokland, P., Holm, M. S., Cazzola, M., Malcovati, L., Tauro, S., Bowen, D., Boultwood, J., Pellagatti, A., Pimanda, J. E., Unnikrishnan, A., Vyas, P., Göhring, G., Schlegelberger, B., Tobiasson, M., Kvalheim, G., Constantinescu, S. N., Nerlov, C., Nilsson, L., Campbell, P. J., Sandberg, R., Papaemmanuil, E., Hellström-Lindberg, E., Linnarsson, S. & Jacobsen, S. E. W., 2014, In : Cancer Cell. 25, 6, p. 794-808

    Research output: Contribution to journalArticle

  39. On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort

    Cortese, D., Sutton, L-A., Cahill, N., Smedby, K. E., Geisler, C., Gunnarsson, R., Gunnar Juliusson, Mansouri, L. & Rosenquist, R., 2014, In : Leukemia. 28, 3, p. 710-713

    Research output: Contribution to journalLetter

  40. Outcome after HSCT in Philadelphia chromosome positive acute lymphoblastic leukemia in Sweden: a population-based study

    Hulegardh, E., Hagglund, H., Ahlberg, L., Karlsson, K., Karbach, H., Markuszewska, A., Persson, I., Astrom, M. & Hallbook, H., 2014, In : Medical Oncology. 31, 8, p. 66

    Research output: Contribution to journalArticle

  41. Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study

    Giagounidis, A., Mufti, G. J., Mittelman, M., Sanz, G., Platzbecker, U., Muus, P., Selleslag, D., Beyne-Rauzy, O., te Boekhorst, P., del Canizo, C., Guerci-Bresler, A., Nilsson, L., Luebbert, M., Quesnel, B., Ganser, A., Bowen, D., Schlegelberger, B., Goehring, G., Fu, T., Benettaib, B. & 2 othersHellstrom-Lindberg, E. & Fenaux, P., 2014, In : European Journal of Haematology. 93, 5, p. 429-438

    Research output: Contribution to journalArticle

  42. Patterns of psychological responses in parents of children that underwent stem cell transplantation

    Riva, R., Forinder, U., Arvidson, J., Mellgren, K., Toporski, J., Winiarski, J. & Norberg, A. L., 2014, In : Psycho-Oncology. 23, 11, p. 1307-1313

    Research output: Contribution to journalArticle

  43. Periostin Secreted by Mesenchymal Stem Cells Supports Tendon Formation in an Ectopic Mouse Model

    Noack, S., Seiffart, V., Willbold, E., Laggies, S., Winkel, A., Shahab-Osterloh, S., Floerkemeier, T., Hertwig, F., Steinhoff, C., Nuber, U., Gross, G. & Hoffmann, A., 2014, In : Stem Cells and Development. 23, 16, p. 1844-1857

    Research output: Contribution to journalArticle

  44. Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells.

    Sara Rolandsson Enes, Andersson Sjöland, A., Brune, J. C., Hongzhe Li, Kassem, M., Fredrik Mertens, Westergren, A., Leif Eriksson, Hansson, L., Skog, I., Leif Bjermer, Stefan Scheding & Gunilla Westergren-Thorsson, 2014, In : BMJ Open Respiratory Research. 1, 1, p. e000027

    Research output: Contribution to journalArticle

  45. Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation and increased expression of extracellular matrix proteins in laminin α2 chain-deficient muscle.

    Menezes de Oliveira, B., Matsumura, C., Fontes Oliveira, C., Kinga Gawlik, Acosta, H., Wernhoff, P. & Madeleine Durbeej-Hjalt, 2014, In : Molecular & Cellular Proteomics. 13, 11, p. 3001-3013

    Research output: Contribution to journalArticle

  46. Regulation of advanced therapy medicinal products in Europe and the role of academia

    Pearce, K. F., Hildebrandt, M., Greinix, H., Stefan Scheding, Koehl, U., Worel, N., Apperley, J., Edinger, M., Hauser, A., Mischak-Weissinger, E., Dickinson, A. M. & Lowdell, M. W., 2014, In : Cytotherapy. 16, 3, p. 289-297

    Research output: Contribution to journalReview article

  47. 2013
  48. High incidence of chronic graft-versus-host disease after myeloablative allogeneic stem cell transplantation for chronic lymphocytic leukemia in Sweden: graft-versus-leukemia effect protects against relapse

    Machaczka, M., Johansson, J-E., Remberger, M., Hallböök, H., Lazarevic, V. L., Wahlin, B. E., Omar, H., Wahlin, A., Gunnar Juliusson, Kimby, E. & Hägglund, H., 2013 Dec, In : Medical Oncology. 30, 4, p. 762

    Research output: Contribution to journalArticle

  49. 450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments

    Cahill, N., Bergh, A-C., Kanduri, M., Goransson-Kultima, H., Mansouri, L., Isaksson, A., Ryan, F., Smedby, K. E., Gunnar Juliusson, Sundstrom, C., Rosen, A. & Rosenquist, R., 2013, In : Leukemia. 27, 1, p. 150-158

    Research output: Contribution to journalArticle

  50. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

    Martin Wahlestedt, Norddahl, G., Sten, G., Amol Ugale, Micha Frisk, M-A., Mattsson, R., Tomas Deierborg, Mikael Sigvardsson & David Bryder, 2013, In : Blood. 121, 21, p. 4257-4264

    Research output: Contribution to journalArticle

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