Agnete Kirkeby

Researcher, PhD, Masters, Bachelors degree
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  1. 2020
  2. Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

    Pedro Rifes, Marc Isaksson, Gaurav Singh Rathore, Patrick Aldrin-Kirk, Oliver Knights Møller, Guido Barzaghi, Julie Lee, Kristoffer Lihme Egerod, Dylan M. Rausch, Malin Parmar, Tune H. Pers, Thomas Laurell & Agnete Kirkeby, 2020 May 25, In : Nature Biotechnology.

    Research output: Contribution to journalArticle

  3. Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells

    Irina Korshunova, Sina Rhein, Diego García-González, Ines Stölting, Ulrich Pfisterer, Anna Barta, Oksana Dmytriyeva, Agnete Kirkeby, Markus Schwaninger & Konstantin Khodosevich, 2020 Feb 27, In : JCI Insight. 5, 4, e126268.

    Research output: Contribution to journalArticle

  4. Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

    Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K. Björklund, Yogita Sharma, Andreas Heuer, Linda Gillberg, Deirdre B. Hoban, Tiago Cardoso, Andrew F. Adler, Marcella Birtele, Hilda Lundén-Miguel, Nikolaos Volakakis, Agnete Kirkeby, Thomas Perlmann & Malin Parmar, 2020, In : Nature Communications. 11, 1, 2434.

    Research output: Contribution to journalArticle

  5. 2019
  6. Parkinson disease and growth factors — is GDNF good enough?

    Agnete Kirkeby & Roger Barker, 2019 Apr 4, In : Nature Reviews Neurology. 15, p. 312 314 p.

    Research output: Contribution to journalDebate/Note/Editorial

  7. 2018
  8. A symphony of stem cells in Vienna - looking to the future

    Enzo R. Porrello & Agnete Kirkeby, 2018 Jun 8, In : Development (Cambridge). 145, 11

    Research output: Contribution to journalArticle

  9. Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

    Tanmoy Mondal, Prasanna Kumar Juvvuna, Agnete Kirkeby, Sanhita Mitra, Subazini Thankaswamy Kosalai, Larissa Traxler, Falk Hertwig, Sara Wernig-Zorc, Caroline Miranda, Lily Deland, Ruth Volland, Christoph Bartenhagen, Deniz Bartsch, Sashidhar Bandaru, Anne Engesser, Santhilal Subhash, Tommy Martinsson, Helena Carén, Levent M. Akyürek, Leo Kurian & 4 others, Meena Kanduri, Maite Huarte, Per Kogner & Matthias Fischer, 2018 Mar 12, In : Cancer Cell. 33, 3, p. 417-434.e7

    Research output: Contribution to journalArticle

  10. Report of the international conference on manufacturing and testing of pluripotent stem cells

    Stewart Abbot, Francisca Agbanyo, Jan Eric Ahlfors, Behnam A. Baghbaderani, Shirley Bartido, Kapil Bharti, Carl Burke, Bjorn Carlsson, Joy Cavagnaro, Abla Creasey, David DiGiusto, Kathy Francissen, Andrew Gaffney, Christopher Goldring, Thorsten Gorba, Elwyn Griffiths, Tadaaki Hanatani, Takao Hayakawa, Tatsuo Heki, Karin Hoogendoorn & 23 others, Shin Kawamata, Hironobu Kimura, Agnete Kirkeby, Ivana Knezevic, Jane Lebkowski, Stephen Lin, Shen Lin-Gibson, Anthony Lubiniecki, Orla O'Shea, Martin Pera, John Petricciani, Gary Pigeau, Anthony Ratcliffe, Yoji Sato, Gerald G. Schumann, William Shingleton, Glyn Stacey (Chair), Stephen Sullivan, Clive N. Svendsen, Jean Hugues Trouvin, Joris Vandeputte, Bao Zhu Yuan & Kathryn Zoon, 2018, In : Biologicals. 56, p. 67-83

    Research output: Contribution to journalDebate/Note/Editorial

  11. 2017
  12. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

    Agnete Kirkeby, Sara Nolbrant, Katarina Tiklova, Andreas Heuer, Nigel Kee, Tiago Cardoso, Daniella Rylander Ottosson, Mariah J. Lelos, Pedro Rifes, Stephen B Dunnett, Shane Grealish, Thomas Perlmann & Malin Parmar, 2017 Jan 5, In : Cell Stem Cell. 20, 1, p. 135-148 14 p.

    Research output: Contribution to journalArticle

  13. Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages

    Nigel Kee, Nikolaos Volakakis, Agnete Kirkeby, Lina Dahl, Helena Storvall, Sara Nolbrant, Laura Lahti, Åsa K. Björklund, Linda Gillberg, Eliza Joodmardi, Rickard Sandberg, Malin Parmar & Thomas Perlmann, 2017 Jan 5, In : Cell Stem Cell. 20, 1, p. 29-40 12 p.

    Research output: Contribution to journalArticle

  14. IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells

    Daniela Lehnen, Serena Barral, Tiago Cardoso, Shane Grealish, Andreas Heuer, Andrej Smiyakin, Agnete Kirkeby, Jutta Kollet, Harold Cremer, Malin Parmar, Andreas Bosio & Sebastian Knöbel, 2017, In : Stem Cell Reports. 9, 4, p. 1207-1220

    Research output: Contribution to journalArticle

  15. Modelling human rostro-caudal neural patterning with a microfluidic morphogenic gradient

    Marc Isaksson, Pedro Rifes, Thomas Laurell & Agnete Kirkeby, 2017, MicroTAS 2017: Savannah, Georgia, USA. Chemical and Biological Microsystems Society, p. 147-148 2 p. (MicroTAS; vol. 2017).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  16. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)

    A. Kirkeby, M. Parmar & R. A. Barker, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Dunnett, S. B. & Björklund, A. (eds.). Vol. 230. p. 165-190 (Progress in Brain Research; vol. 230).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  17. 2016
  18. The stem cell niche finds its true north

    Agnete Kirkeby, Thomas Perlmann & Filipe Pereira, 2016 Aug 15, In : Development: For advances in developmental biology and stem cells. 143, 16, p. 2877-2881 5 p.

    Research output: Contribution to journalReview article

  19. HESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation

    Andreas Heuer, Agnete Kirkeby, Ulrich Pfisterer, Marie E. Jönsson & Malin Parmar, 2016 Aug 1, In : Experimental Neurology. 282, p. 78-85 8 p.

    Research output: Contribution to journalArticle

  20. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

    Roger A Barker, Malin Parmar, Agnete Kirkeby, Anders Björklund, Lachlan Thompson & Patrik Brundin, 2016, In : Journal of Parkinson's Disease. 6, 1, p. 57-63 7 p.

    Research output: Contribution to journalArticle

  21. 2015
  22. 2014
  23. Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.

    Shane Grealish, Elsa Diguet, Agnete Kirkeby, Bengt Mattsson, Andreas Heuer, Yann Bramoulle, Nadja Van Camp, Anselme L Perrier, Philippe Hantraye, Anders Björklund & Malin Parmar, 2014, In : Cell Stem Cell. 15, 5, p. 653-665

    Research output: Contribution to journalArticle

  24. 2012
  25. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol.

    Agnete Kirkeby, Jenny Nelander Wahlestedt & Malin Parmar, 2012, In : Frontiers in Cellular Neuroscience. 6, Published online: 03 January 2013, 64.

    Research output: Contribution to journalArticle

  26. Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions.

    Agnete Kirkeby, Shane Grealish, Daniel Wolf, Jenny Nelander Wahlestedt, James Wood, Martin Lundblad, Olle Lindvall & Malin Parmar, 2012, In : Cell Reports. 1, 6, p. 703-714

    Research output: Contribution to journalArticle

  27. 2011
  28. Using Endogenous MicroRNA Expression Patterns to Visualize Neural Differentiation of Human Pluripotent Stem Cells

    Agnete Kirkeby, Malin Parmar & Johan Jakobsson, 2011 Jul 30, Human Embryonic and Induced Pluripotent Stem Cells: Part of the series Springer Protocols Handbooks . Ye, K. & Jin, S. (eds.). Springer, p. 465-480

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  29. Direct conversion of human fibroblasts to dopaminergic neurons.

    Ulrich Pfisterer, Agnete Kirkeby, Olof Torper, James Wood, Jenny Nelander Wahlestedt, Audrey Dufour, Anders Björklund, Olle Lindvall, Johan Jakobsson & Malin Parmar, 2011, In : Proceedings of the National Academy of Sciences. 108, 25, p. 10343-10348

    Research output: Contribution to journalArticle

  30. 2010
  31. 2008
  32. Therapeutic window for nonerythropoietic carbamylated-erythropoietin to improve motor function following multiple infarct ischemic strokes in New Zealand white rabbits

    PA Lapchak, Agnete Kirkeby, JA Zivin & TN Sager, 2008 Oct 31, In : Behavioural Brain Research. 1238, p. 208-214 doi: 10.1016/j.brainres.2008.08.017.

    Research output: Contribution to journalArticle

  33. High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)

    Agnete Kirkeby, Lars Torup, Louise Bochsen, Marianne Kjalke, Kristin Abel, Kim Theilgaard-Monch, Pär I. Johansson, Søren E. Bjørn, Jens Gerwien & Marcel Leist, 2008 Apr, In : Thrombosis and Haemostasis. 99, 4, p. 720-728 9 p.

    Research output: Contribution to journalArticle

  34. 2007
  35. Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor

    Agnete Kirkeby, Johan van Beek, Jacob Nielsen, Marcel Leist & Lone Helboe, 2007 Aug 15, In : Journal of Neuroscience Methods. 164, 1, p. 50-58 9 p.

    Research output: Contribution to journalArticle

  36. Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures

    Maria Montero, Frantz Rom Poulsen, Jens Noraberg, Agnete Kirkeby, Johan van Beek, Marcel Leist & Jens Zimmer, 2007 Mar, In : Experimental Neurology. 204, 1, p. 106-117 12 p.

    Research output: Contribution to journalArticle