Bernt Nilsson

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  1. 2021
  2. An integrated continuous downstream process with real-time control: A case study with periodic countercurrent chromatography and continuous virus inactivation

    Anton Löfgren, Joaquin Gomis-Fons, Niklas Andersson, Bernt Nilsson, Lotta Berghard & Christine Lagerquist Hägglund, 2021 Jan 12, 18 p.

    Research output: Other contributionMiscellaneous

  3. 2020
  4. Model-based design and control of a small-scale integrated continuous end-to-end mAb platform

    Joaquín Gomis-Fons, Hubert Schwarz, Liang Zhang, Niklas Andersson, Bernt Nilsson, Andreas Castan, Anita Solbrand, Joanne Stevenson & Véronique Chotteau, 2020 Jul, In: Biotechnology Progress. 36, 4, e2995.

    Research output: Contribution to journalArticle

  5. Continuous adsorption in food industry: The recovery of sinapic acid from rapeseed meal extract

    Mónica Moreno-gonzález, Daphne Keulen, Joaquín Gomis-fons, Gustavo Lopez Gomez, Bernt Nilsson & Marcel Ottens, 2020, In: Separation and Purification Technology. 254, 117403.

    Research output: Contribution to journalArticle

  6. 2019
  7. Optimization of integrated chromatography sequences for purification of biopharmaceuticals

    Anton Löfgren, Mikael Yamanee-Nolin, Simon Tallvod, Joaquín G. Fons, Niklas Andersson & Bernt Nilsson, 2019 Nov, In: Biotechnology Progress. 35, 6, e2871.

    Research output: Contribution to journalArticle

  8. Model-based monitoring of industrial reversed phase chromatography to predict insulin variants

    Patricia Roch, Anton Sellberg, Niklas Andersson, Matthias Gunne, Peter Hauptmann, Bernt Nilsson & Carl Fredrik Mandenius, 2019 Jul, In: Biotechnology Progress. 35, 4, e2813.

    Research output: Contribution to journalArticle

  9. Single-shooting optimization of an industrial process through co-simulation of a modularized Aspen Plus Dynamics model

    Mikael Yamanee-Nolin, Anton Löfgren, Niklas Andersson, Bernt Nilsson, Mark Max-Hansen & Oleg Pajalic, 2019 Jun 16, Computer Aided Chemical Engineering. Elsevier Science Publishers B.V., p. 721-726 6 p. (Computer Aided Chemical Engineering; vol. 46).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  10. Integration of a complete downstream process for the automated lab-scale production of a recombinant protein

    Joaquín Gomis-Fons, Anton Löfgren, Niklas Andersson, Bernt Nilsson, Lotta Berghard & Susanne Wood, 2019, In: Journal of Biotechnology. 301, p. 45-51 7 p.

    Research output: Contribution to journalArticle

  11. 2018
  12. Mechanistic Modeling of Reversed-Phase Chromatography of Insulins within the Temperature Range 10–40 °C

    Karolina Arkell, Martin P. Breil, Søren S. Frederiksen & Bernt Nilsson, 2018 Feb 14, In: ACS Omega. 3, 2, p. 1946–1954 9 p.

    Research output: Contribution to journalArticle

  13. Designing an Autonomous Integrated Downstream Sequence From a Batch Separation Process − An Industrial Case Study

    Anton Löfgren, Niklas Andersson, Anton Sellberg, Bernt Nilsson, Magnus Löfgren & Susanne Wood, 2018 Jan 30, In: Biotechnology Journal. 5 p.

    Research output: Contribution to journalArticle

  14. Multi-flowrate Optimization of the Loading Phase of a Preparative Chromatographic Separation

    Anton Sellberg, Mikael Nolin, Anton Löfgren, Niklas Andersson & Bernt Nilsson, 2018 Jan 1, Computer Aided Chemical Engineering. The Association for the Study of Animal Behaviour / Elsevier B.V., p. 1619-1624 6 p. (Computer Aided Chemical Engineering; vol. 43).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  15. Pareto-optimal reversed-phase chromatography separation of three insulin variants with a solubility constraint

    Karolina Arkell, Hans Kristian Knutson, Søren S. Frederiksen, Martin P. Breil & Bernt Nilsson, 2018 Jan, In: Journal of Chromatography A. 1532, p. 98-104

    Research output: Contribution to journalArticle

  16. 2017
  17. Robust Multi-Objective Optimization of Chromatographic Rare Earth Element Separation

    Hans-Kristian Knutson, Anders Holmqvist, Niklas Andersson & Bernt Nilsson, 2017 Oct 31, In: Advances in chemical Engineering and Science. 7, 4, p. 477-493 17 p.

    Research output: Contribution to journalArticle

  18. Development and Optimization of a Single Column Analog Model for a Multi-Column Counter-Current Solvent Gradient Purification Process

    Anton Sellberg, Niklas Andersson, Anders Holmqvist & Bernt Nilsson, 2017 Oct 1, 27th European Symposium on Computer Aided Process Engineering. Espuña, A., Graells, M. & Puigjaner, L. (eds.). Barcelona, Vol. 40. p. 187-192 6 p. (Computer Aided Chemical Engineering; vol. 40).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  19. Unbiased Selection of Decision Variables for Optimization

    Mikael Yamanee-Nolin, Niklas Andersson, Bernt Nilsson, Mark Max-Hansen & Oleg Pajalic, 2017 Oct 1, 27 European Symposium on Computer Aided Process Engineering. Espuña, A., Graells, M. & Puigjaner, L. (eds.). Elsevier, Vol. 40. p. 253-258 6 p. (Computer Aided Chemical Engineering; vol. 40).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  20. Design and control of integrated chromatography column sequences

    Niklas Andersson, Anton Löfgren, Marianne Olofsson, Anton Sellberg, Bernt Nilsson & Peter Tiainen, 2017 Feb 3, In: Biotechnology Progress. 00, 00, 8 p.

    Research output: Contribution to journalArticle

  21. Discretized multi-level elution trajectory: A proof-of-concept demonstration

    Anton Sellberg, Anders Holmqvist, Fredrik Magnusson, Christian Andersson & Bernt Nilsson, 2017 Jan 20, In: Journal of Chromatography A. 1481, p. 73-81 9 p.

    Research output: Contribution to journalArticle

  22. Mechanistic Modeling of Reversed-Phase Chromatography of Insulins with Potassium Chloride and Ethanol as Mobile-Phase Modulators

    Karolina Arkell, Martin P. Breil, Søren Søndergaard Frederiksen & Bernt Nilsson, 2017 Jan 19, In: ACS Omega. 2, p. 136-146

    Research output: Contribution to journalArticle

  23. 2016
  24. Method development in inverse modeling applied to supercritical fluid extraction of lipids

    Victor Abrahamsson, Niklas Andersson, Bernt Nilsson & Charlotta Turner, 2016 May 1, In: Journal of Supercritical Fluids. 111, p. 14-27 14 p.

    Research output: Contribution to journalArticle

  25. LCCC Workshop on Process Control

    Charlotta Johnsson (ed.), Tore Hägglund (ed.), Bernt Nilsson (ed.), Kristian Soltesz (ed.) & Eva Westin (ed.), 2016, Department of Automatic Control, Lund Institute of Technology, Lund University. (Technical Reports TFRT-7649)

    Research output: Book/ReportConference proceeding (editor)

  26. 2015
  27. Parameter Selection in the Parameter Estimation of Grade Transitions in a Polyethylene Plant

    Niklas Andersson, Per-Ola Larsson, Johan Åkesson, Niclas Carlsson, Staffan Skålén & Bernt Nilsson, 2015 Sep 21, In: Studies in Engineering and Technology. 3, 1, p. 1-18 18 p.

    Research output: Contribution to journalArticle

  28. Combined effects of potassium chloride and ethanol as mobile phase modulators on hydrophobic interaction and reversed-phase chromatography of three insulin variants

    Karolina Johansson, Søren S. Frederiksen, Marcus Degerman, Martin P. Breil, Jørgen M. Mollerup & Bernt Nilsson, 2015, In: Journal of Chromatography A. 1381, p. 64-73

    Research output: Contribution to journalArticle

  29. Dynamic Multi-Objective Optimization of Batch Chromatographic Separation Processes

    Anders Holmqvist, Fredrik Magnusson & Bernt Nilsson, 2015, Computer Aided Chemical Engineering. Gernaey, K. V., Huusom, J. K. & Gani, R. (eds.). Elsevier, Vol. 37. p. 815-820 6 p.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  30. Model-Based Comparison of Antibody Dimerization in Continuous and Batch-Wise Downstream Processing

    Anton Sellberg, Frida Ojala & Bernt Nilsson, 2015, In: Antibodies. 4, 3, p. 157-169

    Research output: Contribution to journalArticle

  31. Modeling Preparative Chromatographic Separation of Heavy Rare Earth Elements and Optimization of Thulium Purification

    Mark Max-Hansen, Hans-Kristian Knutson, Christian Jönsson, Marcus Degerman & Bernt Nilsson, 2015, In: Advances in Materials Physics and Chemistry. 5, 5, p. 151-160

    Research output: Contribution to journalArticle

  32. Multi-Objective Optimization of Chromatographic Rare Earth Element Separation

    Hans-Kristian Knutson, Anders Holmqvist & Bernt Nilsson, 2015, In: Journal of Chromatography A. 1416, p. 57-63

    Research output: Contribution to journalArticle

  33. Prediction of reversible IgG1 aggregation occurring in a size exclusion chromatography column is enabled through a model based approach

    Frida Ojala, Anton Sellberg, Thomas Budde Hansen, Ernst Broberg Hansen & Bernt Nilsson, 2015, In: Biotechnology Journal. 10, 11, p. 1814-1821

    Research output: Contribution to journalArticle

  34. 2014
  35. Experimental productivity rate optimization of rare earth element separation through preparative solid phase extraction chromatography.

    Hans-Kristian Knutson, Mark Max-Hansen, Christian Jönsson, Niklas Borg & Bernt Nilsson, 2014, In: Journal of Chromatography A. 1348, p. 47-51

    Research output: Contribution to journalArticle

  36. Model-Based Comparison of Batch and Continuous Preparative Chromatography in the Separation of Rare Earth Elements

    Niklas Andersson, Hans-Kristian Knutson, Mark Max-Hansen, Niklas Borg & Bernt Nilsson, 2014, In: Industrial & Engineering Chemistry Research. 53, 42, p. 16485-16493

    Research output: Contribution to journalArticle

  37. Model-based design and integration of a two-step biopharmaceutical production process.

    Bruno Otero, Marcus Degerman, Thomas Budde Hansen, Ernst Broberg Hansen & Bernt Nilsson, 2014, In: Bioprocess and Biosystems Engineering. 37, 10, p. 1989-1996

    Research output: Contribution to journalArticle

  38. Modeling and robust pooling design of a preparative cation-exchange chromatography step for purification of monoclonal antibody monomer from aggregates.

    Niklas Borg, Yan Brodsky, John Moscariello, Suresh Vunnum, Ganesh Vedantham, Karin Westerberg & Bernt Nilsson, 2014, In: Journal of Chromatography A. 1359, p. 170-181

    Research output: Contribution to journalArticle

  39. Prediction of IgG1 aggregation in solution.

    Frida Ojala, Marcus Degerman, Thomas Budde Hansen, Ernst Broberg Hansen & Bernt Nilsson, 2014, In: Biotechnology Journal. 9, 6, p. 800-804

    Research output: Contribution to journalArticle

  40. 2013
  41. Effects of uncertainties in experimental conditions on the estimation of adsorption model parameters in preparative chromatography

    Niklas Borg, Karin Westerberg, Niklas Andersson, Eric von Lieres & Bernt Nilsson, 2013, In: Computers & Chemical Engineering. 55, p. 148-157

    Research output: Contribution to journalArticle

  42. Mechanistic modelling of drug release from a polymer matrix using magnetic resonance microimaging.

    Erik Kaunisto, Farhad Tajarobi, Susanna Abrahmsen-Alami, Anette Larsson, Bernt Nilsson & Anders Axelsson, 2013, In: European Journal of Pharmaceutical Sciences. 48, 4-5, p. 698-708

    Research output: Contribution to journalArticle

  43. Model-based risk analysis of coupled process steps.

    Karin Westerberg, Ernst Broberg-Hansen, Lars Sejergaard & Bernt Nilsson, 2013, In: Biotechnology and Bioengineering. 110, 9, p. 2462-2470

    Research output: Contribution to journalArticle

  44. Modeling the Synergies of Saline and Organic Modifiers on RPC Separation

    Karolina Johansson, Søren Søndergaard Frederiksen, Marcus Degerman, Martin P. Breil, Jørgen Mollerup & Bernt Nilsson, 2013.

    Research output: Contribution to conferenceAbstract

  45. 2012
  46. Model-Based Process Challenge of an Industrial Ion-Exchange Chromatography Step

    Karin Westerberg, Ernst Broberg Hansen, Marcus Degerman, Thomas Budde Hansen & Bernt Nilsson, 2012, In: Chemical Engineering & Technology. 35, 1, p. 183-190

    Research output: Contribution to journalArticle

  47. Modelling and optimisation of preparative chromatographic purification of europium.

    Frida Ojala, Mark Max-Hansen, Dejene Kifle, Niklas Borg & Bernt Nilsson, 2012, In: Journal of chromatography. A. 1220, p. 21-25

    Research output: Contribution to journalArticle

  48. Supporting Design and Control of a Reversed-Phase Chromatography Step by Mechanistic Modeling

    Karin Westerberg, Niklas Borg, Niklas Andersson & Bernt Nilsson, 2012, In: Chemical Engineering & Technology. 35, 1, p. 169-175

    Research output: Contribution to journalArticle

  49. 2011
  50. Calibration of a polyethylene plant for grade change optimisations

    Niklas Andersson, Per-Ola Larsson, Johan Åkesson, Staffan Haugwitz & Bernt Nilsson, 2011, 21ST European Symposium on Computer Aided Process Engineering. Elsevier, Vol. 29. p. 673-677

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  51. Optimization of preparative chromatographic separation of multiple rare earth elements.

    Mark Max-Hansen, Frida Ojala, Dejene Kifle, Niklas Borg & Bernt Nilsson, 2011, In: Journal of Chromatography A. 1218, 51, p. 9155-9161

    Research output: Contribution to journalArticle

  52. 2010
  53. A mechanistic modelling approach to polymer dissolution using magnetic resonance microimaging.

    Erik Kaunisto, Susanna Abrahmsen-Alami, Per Borgquist, Anette Larsson, Bernt Nilsson & Anders Axelsson, 2010, In: Journal of Controlled Release. 147, p. 232-241

    Research output: Contribution to journalArticle

  54. Osmotic pumping release from ethyl-hydroxypropyl-cellulose-coated pellets: A new mechanistic model.

    Mariagrazia Marucci, Gert Ragnarsson, Bernt Nilsson & Anders Axelsson, 2010, In: Journal of Controlled Release. 142, p. 53-60

    Research output: Contribution to journalArticle

  55. Pooling control in variable preparative chromatography processes.

    Karin Westerberg, Marcus Degerman & Bernt Nilsson, 2010, In: Bioprocess and Biosystems Engineering. 33, p. 375-382

    Research output: Contribution to journalArticle

  56. 2009
  57. A Model-Based Approach to Determine the Design Space of Preparative Chromatography

    Marcus Degerman, Karin Westerberg & Bernt Nilsson, 2009, In: Chemical Engineering & Technology. 32, 8, p. 1195-1202

    Research output: Contribution to journalArticle

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