Bernt Nilsson

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  1. 2020
  2. Model-based design and control of a small-scale integrated continuous end-to-end mAb platform

    Gomis-Fons, J., Schwarz, H., Zhang, L., Niklas Andersson, Bernt Nilsson, Castan, A., Solbrand, A., Stevenson, J. & Chotteau, V., 2020 Mar 31, In : Biotechnology Progress. e2995.

    Research output: Contribution to journalArticle

  3. 2019
  4. Optimization of integrated chromatography sequences for purification of biopharmaceuticals

    Löfgren, A., Mikael Yamanee-Nolin, Tallvod, S., Fons, J. G., Niklas Andersson & Bernt Nilsson, 2019 Nov, In : Biotechnology Progress. 35, 6, e2871.

    Research output: Contribution to journalArticle

  5. Model-based monitoring of industrial reversed phase chromatography to predict insulin variants

    Roch, P., Sellberg, A., Niklas Andersson, Gunne, M., Hauptmann, P., Bernt Nilsson & Mandenius, C. F., 2019 Jul, In : Biotechnology Progress. 35, 4, e2813.

    Research output: Contribution to journalArticle

  6. Single-shooting optimization of an industrial process through co-simulation of a modularized Aspen Plus Dynamics model

    Mikael Yamanee-Nolin, Löfgren, A., Niklas Andersson, Bernt Nilsson, Max-Hansen, M. & Pajalic, O., 2019 Jun 16, Computer Aided Chemical Engineering. Elsevier Science Publishers B.V., p. 721-726 6 p. (Computer Aided Chemical Engineering; vol. 46).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  7. Integration of a complete downstream process for the automated lab-scale production of a recombinant protein

    Gomis-Fons, J., Löfgren, A., Niklas Andersson, Bernt Nilsson, Berghard, L. & Wood, S., 2019, In : Journal of Biotechnology. 301, p. 45-51 7 p.

    Research output: Contribution to journalArticle

  8. 2018
  9. Mechanistic Modeling of Reversed-Phase Chromatography of Insulins within the Temperature Range 10–40 °C

    Arkell, K., Breil, M. P., Frederiksen, S. S. & Bernt Nilsson, 2018 Feb 14, In : ACS Omega. 3, 2, p. 1946–1954 9 p.

    Research output: Contribution to journalArticle

  10. Designing an Autonomous Integrated Downstream Sequence From a Batch Separation Process − An Industrial Case Study

    Löfgren, A., Niklas Andersson, Sellberg, A., Bernt Nilsson, Löfgren, M. & Wood, S., 2018 Jan 30, In : Biotechnology Journal. 5 p.

    Research output: Contribution to journalArticle

  11. Multi-flowrate Optimization of the Loading Phase of a Preparative Chromatographic Separation

    Sellberg, A., Mikael Nolin, Löfgren, A., Niklas Andersson & Bernt Nilsson, 2018 Jan 1, Computer Aided Chemical Engineering. The Association for the Study of Animal Behaviour / Elsevier B.V., p. 1619-1624 6 p. (Computer Aided Chemical Engineering; vol. 43).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  12. Pareto-optimal reversed-phase chromatography separation of three insulin variants with a solubility constraint

    Arkell, K., Knutson, H. K., Frederiksen, S. S., Breil, M. P. & Bernt Nilsson, 2018 Jan, In : Journal of Chromatography A. 1532, p. 98-104

    Research output: Contribution to journalArticle

  13. 2017
  14. Robust Multi-Objective Optimization of Chromatographic Rare Earth Element Separation

    Knutson, H-K., Holmqvist, A., Niklas Andersson & Bernt Nilsson, 2017 Oct 31, In : Advances in chemical Engineering and Science. 7, 4, p. 477-493 17 p.

    Research output: Contribution to journalArticle

  15. Development and Optimization of a Single Column Analog Model for a Multi-Column Counter-Current Solvent Gradient Purification Process

    Sellberg, A., Niklas Andersson, Holmqvist, A. & Bernt Nilsson, 2017 Oct 1, 27th European Symposium on Computer Aided Process Engineering. Espuña, A., Graells, M. & Puigjaner, L. (eds.). Barcelona, Vol. 40. p. 187-192 6 p. (Computer Aided Chemical Engineering; vol. 40).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  16. Unbiased Selection of Decision Variables for Optimization

    Mikael Yamanee-Nolin, Niklas Andersson, Bernt Nilsson, Max-Hansen, M. & Pajalic, O., 2017 Oct 1, 27 European Symposium on Computer Aided Process Engineering. Espuña, A., Graells, M. & Puigjaner, L. (eds.). Elsevier, Vol. 40. p. 253-258 6 p. (Computer Aided Chemical Engineering; vol. 40).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  17. Design and control of integrated chromatography column sequences

    Niklas Andersson, Löfgren, A., Olofsson, M., Sellberg, A., Bernt Nilsson & Tiainen, P., 2017 Feb 3, In : Biotechnology Progress. 00, 00, 8 p.

    Research output: Contribution to journalArticle

  18. Discretized multi-level elution trajectory: A proof-of-concept demonstration

    Sellberg, A., Holmqvist, A., Magnusson, F., Andersson, C. & Bernt Nilsson, 2017 Jan 20, In : Journal of Chromatography A. 1481, p. 73-81 9 p.

    Research output: Contribution to journalArticle

  19. Mechanistic Modeling of Reversed-Phase Chromatography of Insulins with Potassium Chloride and Ethanol as Mobile-Phase Modulators

    Arkell, K., Breil, M. P., Søndergaard Frederiksen, S. & Bernt Nilsson, 2017 Jan 19, In : ACS Omega. 2, p. 136-146

    Research output: Contribution to journalArticle

  20. 2016
  21. Method development in inverse modeling applied to supercritical fluid extraction of lipids

    Abrahamsson, V., Niklas Andersson, Bernt Nilsson & Charlotta Turner, 2016 May 1, In : Journal of Supercritical Fluids. 111, p. 14-27 14 p.

    Research output: Contribution to journalArticle

  22. LCCC Workshop on Process Control

    Charlotta Johnsson (ed.), Tore Hägglund (ed.), Bernt Nilsson (ed.), Kristian Soltesz (ed.) & Eva Westin (ed.), 2016, Department of Automatic Control, Lund Institute of Technology, Lund University. (Technical Reports TFRT-7649)

    Research output: Book/ReportConference proceeding (editor)

  23. 2015
  24. Parameter Selection in the Parameter Estimation of Grade Transitions in a Polyethylene Plant

    Niklas Andersson, Larsson, P-O., Åkesson, J., Carlsson, N., Skålén, S. & Bernt Nilsson, 2015 Sep 21, In : Studies in Engineering and Technology. 3, 1, p. 1-18 18 p.

    Research output: Contribution to journalArticle

  25. Combined effects of potassium chloride and ethanol as mobile phase modulators on hydrophobic interaction and reversed-phase chromatography of three insulin variants

    Johansson, K., Frederiksen, S. S., Degerman, M., Breil, M. P., Mollerup, J. M. & Bernt Nilsson, 2015, In : Journal of Chromatography A. 1381, p. 64-73

    Research output: Contribution to journalArticle

  26. Dynamic Multi-Objective Optimization of Batch Chromatographic Separation Processes

    Holmqvist, A., Magnusson, F. & Bernt Nilsson, 2015, Computer Aided Chemical Engineering. Gernaey, K. V., Huusom, J. K. & Gani, R. (eds.). Elsevier, Vol. 37. p. 815-820 6 p.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  27. Model-Based Comparison of Antibody Dimerization in Continuous and Batch-Wise Downstream Processing

    Sellberg, A., Ojala, F. & Bernt Nilsson, 2015, In : Antibodies. 4, 3, p. 157-169

    Research output: Contribution to journalArticle

  28. Modeling Preparative Chromatographic Separation of Heavy Rare Earth Elements and Optimization of Thulium Purification

    Max-Hansen, M., Knutson, H-K., Jönsson, C., Degerman, M. & Bernt Nilsson, 2015, In : Advances in Materials Physics and Chemistry. 5, 5, p. 151-160

    Research output: Contribution to journalArticle

  29. Multi-Objective Optimization of Chromatographic Rare Earth Element Separation

    Knutson, H-K., Holmqvist, A. & Bernt Nilsson, 2015, In : Journal of Chromatography A. 1416, p. 57-63

    Research output: Contribution to journalArticle

  30. Prediction of reversible IgG1 aggregation occurring in a size exclusion chromatography column is enabled through a model based approach

    Ojala, F., Sellberg, A., Budde Hansen, T., Broberg Hansen, E. & Bernt Nilsson, 2015, In : Biotechnology Journal. 10, 11, p. 1814-1821

    Research output: Contribution to journalArticle

  31. 2014
  32. Experimental productivity rate optimization of rare earth element separation through preparative solid phase extraction chromatography.

    Knutson, H-K., Max-Hansen, M., Jönsson, C., Borg, N. & Bernt Nilsson, 2014, In : Journal of Chromatography A. 1348, p. 47-51

    Research output: Contribution to journalArticle

  33. Model-Based Comparison of Batch and Continuous Preparative Chromatography in the Separation of Rare Earth Elements

    Niklas Andersson, Knutson, H-K., Max-Hansen, M., Borg, N. & Bernt Nilsson, 2014, In : Industrial & Engineering Chemistry Research. 53, 42, p. 16485-16493

    Research output: Contribution to journalArticle

  34. Model-based design and integration of a two-step biopharmaceutical production process.

    Otero, B., Degerman, M., Hansen, T. B., Hansen, E. B. & Bernt Nilsson, 2014, In : Bioprocess and Biosystems Engineering. 37, 10, p. 1989-1996

    Research output: Contribution to journalArticle

  35. Modeling and robust pooling design of a preparative cation-exchange chromatography step for purification of monoclonal antibody monomer from aggregates.

    Borg, N., Brodsky, Y., Moscariello, J., Vunnum, S., Vedantham, G., Westerberg, K. & Bernt Nilsson, 2014, In : Journal of Chromatography A. 1359, p. 170-181

    Research output: Contribution to journalArticle

  36. Prediction of IgG1 aggregation in solution.

    Ojala, F., Degerman, M., Budde Hansen, T., Broberg Hansen, E. & Bernt Nilsson, 2014, In : Biotechnology Journal. 9, 6, p. 800-804

    Research output: Contribution to journalArticle

  37. 2013
  38. Mechanistic modelling of drug release from a polymer matrix using magnetic resonance microimaging.

    Kaunisto, E., Tajarobi, F., Abrahmsen-Alami, S., Larsson, A., Bernt Nilsson & Anders Axelsson, 2013, In : European Journal of Pharmaceutical Sciences. 48, 4-5, p. 698-708

    Research output: Contribution to journalArticle

  39. Model-based risk analysis of coupled process steps.

    Westerberg, K., Broberg-Hansen, E., Sejergaard, L. & Bernt Nilsson, 2013, In : Biotechnology and Bioengineering. 110, 9, p. 2462-2470

    Research output: Contribution to journalArticle

  40. Modeling the Synergies of Saline and Organic Modifiers on RPC Separation

    Johansson, K., Søndergaard Frederiksen, S., Degerman, M., Breil, M. P., Mollerup, J. & Bernt Nilsson, 2013.

    Research output: Contribution to conferenceAbstract

  41. 2012
  42. Model-Based Process Challenge of an Industrial Ion-Exchange Chromatography Step

    Westerberg, K., Broberg Hansen, E., Degerman, M., Budde Hansen, T. & Bernt Nilsson, 2012, In : Chemical Engineering & Technology. 35, 1, p. 183-190

    Research output: Contribution to journalArticle

  43. Modelling and optimisation of preparative chromatographic purification of europium.

    Ojala, F., Max-Hansen, M., Kifle, D., Borg, N. & Bernt Nilsson, 2012, In : Journal of chromatography. A. 1220, p. 21-25

    Research output: Contribution to journalArticle

  44. Supporting Design and Control of a Reversed-Phase Chromatography Step by Mechanistic Modeling

    Westerberg, K., Borg, N., Niklas Andersson & Bernt Nilsson, 2012, In : Chemical Engineering & Technology. 35, 1, p. 169-175

    Research output: Contribution to journalArticle

  45. 2011
  46. Calibration of a polyethylene plant for grade change optimisations

    Niklas Andersson, Larsson, P-O., Åkesson, J., Haugwitz, S. & Bernt Nilsson, 2011, 21ST European Symposium on Computer Aided Process Engineering. Elsevier, Vol. 29. p. 673-677

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  47. Optimization of preparative chromatographic separation of multiple rare earth elements.

    Max-Hansen, M., Ojala, F., Kifle, D., Borg, N. & Bernt Nilsson, 2011, In : Journal of Chromatography A. 1218, 51, p. 9155-9161

    Research output: Contribution to journalArticle

  48. 2010
  49. A mechanistic modelling approach to polymer dissolution using magnetic resonance microimaging.

    Kaunisto, E., Abrahmsen-Alami, S., Borgquist, P., Larsson, A., Bernt Nilsson & Anders Axelsson, 2010, In : Journal of Controlled Release. 147, p. 232-241

    Research output: Contribution to journalArticle

  50. Osmotic pumping release from ethyl-hydroxypropyl-cellulose-coated pellets: A new mechanistic model.

    Marucci, M., Ragnarsson, G., Bernt Nilsson & Anders Axelsson, 2010, In : Journal of Controlled Release. 142, p. 53-60

    Research output: Contribution to journalArticle

  51. Pooling control in variable preparative chromatography processes.

    Westerberg, K., Degerman, M. & Bernt Nilsson, 2010, In : Bioprocess and Biosystems Engineering. 33, p. 375-382

    Research output: Contribution to journalArticle

  52. 2009
  53. A Model-Based Approach to Determine the Design Space of Preparative Chromatography

    Degerman, M., Westerberg, K. & Bernt Nilsson, 2009, In : Chemical Engineering & Technology. 32, 8, p. 1195-1202

    Research output: Contribution to journalArticle

  54. Determining Critical Process Parameters and Process Robustness in Preparative Chromatography - A Model-Based Approach

    Degerman, M., Westerberg, K. & Bernt Nilsson, 2009, In : Chemical Engineering & Technology. 32, 6, p. 903-911

    Research output: Contribution to journalArticle

  55. Simultaneous modeling and optimization of preparative chromatography

    Westerberg, K., Nielsen, F., Degerman, M. & Bernt Nilsson, 2009, In : New Biotechnology. 25, Suppl. 1, p. S183-S183

    Research output: Contribution to journalPublished meeting abstract

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