Filipe Pereira

Associate Senior Lecturer, Wallenberg Molecular Medicine FellowKnown as name: Carlos-Filipe Pereira

Research areas and keywords

UKÄ subject classification

  • Cell and Molecular Biology
  • Developmental Biology
  • Medical and Health Sciences
  • Basic Medicine

Keywords

  • Hematopoiesis, Cellular Reprogramming

Research

The focus of my research is to understand the molecular determinants underlying cellular reprogramming and hematopoietic specification. Cellular reprogramming can be achieved experimentally in different ways, including nuclear transfer, cell fusion or expression of transcription factors. The emergent ability to reprogram any human cell into desired hematopoietic cell-types is opening avenues to the discovery of new therapies for immune and blood diseases. The goals of my laboratory are a) to understand at the molecular level how hematopoietic cellular identities are specified employing cellular reprogramming and b) to use this knowledge to manipulate genes and pathways that ultimately may allow the generation of patient-specific hematopoietic cells for regenerative medicine and immunotherapy.

Highlighted research outputs

Fábio F. Rosa, Cristiana F. Pires, Kurochkin, I., Alexandra G. Ferreira, Gomes, A. M., Palma, L. G., Shaiv, K., Solanas, L., Azenha, C., Papatsenko, D., Schulz, O., E Sousa, C. R. & Carlos Filipe Pereira, 2018 Dec 7, In : Science immunology. 3, 30, eaau4292.

Research output: Contribution to journalArticle

Gomes, A. M., Kurochkin, I., Chang, B., Daniel, M., Law, K., Satija, N., Lachmann, A., Wang, Z., Ferreira, L., Ma'ayan, A., Chen, B. K., Papatsenko, D., Lemischka, I. R., Moore, K. A. & Carlos Filipe Pereira, 2018, In : Cell Reports.

Research output: Contribution to journalArticle

Carlos Filipe Pereira, Chang, B., Gomes, A., Bernitz, J. M., Papatsenko, D., Niu, X., Swiers, G., Azzoni, E., de Bruijn, M. F. T. R., Schaniel, C., Lemischka, I. R. & Moore, K. A., 2016 Mar 7, In : Developmental Cell. 36, 5, p. 525-539 15 p.

Research output: Contribution to journalArticle

Carlos Filipe Pereira, Chang, B., Qiu, J., Niu, X., Papatsenko, D., Hendry, C. E., Clark, N. R., Nomura-Kitabayashi, A., Kovacic, J. C., Ma'Ayan, A., Schaniel, C., Lemischka, I. R. & Moore, K., 2013 Aug 1, In : Cell Stem Cell. 13, 2, p. 205-218 14 p.

Research output: Contribution to journalArticle

Carlos-Filipe Pereira, Lemischka, I. R. & Moore, K., 2012 Aug, In : Annals of the New York Academy of Sciences. 1266, 1, p. 7-17 11 p.

Research output: Contribution to journalArticle

Carlos F. Pereira, Piccolo, F. M., Tsubouchi, T., Sauer, S. P. A., Ryan, N. K., Bruno, L., Landeira, D., Santos, J., Banito, A., Gil, J., Koseki, H., Merkenschlager, M. & Fisher, A. G., 2010 Jun 4, In : Cell Stem Cell. 6, 6, p. 547-556 10 p.

Research output: Contribution to journalArticle

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