Gunnar Juliusson

Professor, specialist Physician

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology

Keywords

  • Hematologic cancers, genetics, epidemiology

Research

Molecular characterization and epidemiology of acute myeloid leukemia (AML)in adults. Swedish patients with AML have been prospectively reported to the nationalBlood Cancer Registry since 1997, which now contains data on diagnosticresults, management and outcome for more than 6000 patients(http://www.cancercentrum.se/samverkan/cancerdiagnoser/blod-lymfom-myelom/akut-myeloisk-leukemi-aml-inkl-akut-oklassificerad-leukemi-aul/kvalitetsregister/), and represents an unique database with real worlddata, especially for the majority of patients that are older (median age 71years). Since 2014 all new AML patients in our department have a bonemarrow sampled for next generation sequencing including whole exome andRNA sequencing. A comparison with constitutional DNA from skin biopsy isperformed to assess leukemia-specific abnormalities. Follow-up samples toassess minimal residual disease and clonal changes at subsequent diseasedevelopment is also collected and analyzed. Rare clinicopathologicalassociations are being identified, and clinical associations defined, in closecollaboration between laboratory and clinical department.

Highlighted research outputs

Gunnar Juliusson, Petar Antunovic, Asa Derolf, Soren Lehmann, Lars Mollgard, Dick Stockelberg, Ulf Tidefelt, Anders Wahlin & Martin Hoglund, 2009, In: Blood. 113, 18, p. 4179-4187

Research output: Contribution to journalArticle

Vladimir Lazarevic, Ann-sofi Hörstedt, Bertil Johansson, P Antunovic, R Billström, A Derolf, E Hulegårdh, S Lehmann, L Möllgård, C Nilsson, Stefan Peterson, D Stockelberg, B Uggla, L Wennström, A Wahlin, M Höglund & Gunnar Juliusson, 2014, In: Blood Cancer Journal. 4, Feb 28, e188.

Research output: Contribution to journalArticle

Erik Hulegardh, Christer Nilsson, Vladimir Lazarevic, Hege Garelius, Petar Antunovic, Asa Rangert Derolf, Lars Mollgard, Bertil Uggla, Lovisa Wennstrom, Anders Wahlin, Martin Hoglund, Gunnar Juliusson, Dick Stockelberg & Soren Lehmann, 2015, In: American Journal of Hematology. 90, 3, p. 208-214

Research output: Contribution to journalArticle

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