Gunther Helms

Senior Lecturer, Docent, , , PhD, MSc
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  1. 2020
  2. Non-negative least squares computation for in vivo myelin mapping using simulated multi-echo spin-echo T2 decay data

    Wiggermann, V., Kolind, S. L., Vavasour, I. M., MacKay, A. L., Gunther Helms & Rauscher, A., 2020 Mar 3, In : NMR in Biomedicine.

    Research output: Contribution to journalArticle

  3. 2019
  4. The impact of endurance training and table soccer on brain metabolites in schizophrenia

    Rauchmann, B. S., Ghaseminejad, F., Keeser, D., Keller-Varady, K., Schneider-Axmann, T., Takahashi, S., Karali, T., Gunther Helms, Dechent, P., Maurus, I., Hasan, A., Wobrock, T., Ertl-Wagner, B., Schmitt, A., Malchow, B. & Falkai, P., 2019 Nov, In : Brain Imaging and Behavior.

    Research output: Contribution to journalArticle

  5. Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol

    Hampus Olsson, Andersen, M., Jimmy Lätt, Ronnie Wirestam & Gunther Helms, 2019 Apr 29, Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 4 p. 309. (Proceedings of the ISMRM; vol. 27).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  6. Characterising the temporal evolution of fixation in human post mortem brain via linear relaxometry modelling – a marker of cross-linking?

    Mohammadi, S., Papazoglou, S., Mushumba, H., Ashtarayeh, M., Püschel, K., Gunther Helms, Callaghan, M. F., Weiskopf, N. & Streubel, T., 2019 Apr 26, Characterising the temporal evolution of fixation in human post mortem brain via linear relaxometry modelling – a marker of cross-linking?. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 3 p. 4986

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  7. Non-negative least squares fitting of multi-exponential T2 decay data: Are we able to accurately measure the fraction of myelin water?

    Wiggermann, V., Vavasour, I. M., Hernandez-Torres, E., Gunther Helms, MacKay, A. L. & Rauscher, A., 2019 Apr 26, Non-negative least squares fitting of multi-exponential T2 decay data: Are we able to accurately measure the fraction of myelin water?. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 3 p. 4402. (Proceedings of the ISMRM; vol. 27).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  8. Removing bias and increasing dynamic range in DREAM flip angle mapping at 7T

    Gunther Helms, Hampus Olsson & Andersen, M., 2019 Apr 26, Removing bias and increasing dynamic range in DREAM flip angle mapping at 7T. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 3 p. 4500. (Proc Intl Soc Magn Reson Med; vol. 27).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  9. Example dataset for the hMRI toolbox

    Callaghan, M. F., Lutti, A., Ashburner, J., Balteau, E., Corbin, N., Draganski, B., Gunther Helms, Kherif, F., Leutritz, T., Mohammadi, S., Philips, C., Reimer, E., Ruthotto, L., Seif, M., Tabelow, K., Ziegler, G. & Weiskopf, N., 2019, In : Data in Brief. 104132.

    Research output: Contribution to journalArticle

  10. hMRI – A toolbox for quantitative MRI in neuroscience and clinical research

    Tabelow, K., Balteau, E., Ashburner, J., Callaghan, M. F., Draganski, B., Gunther Helms, Kherif, F., Leutritz, T., Lutti, A., Philips, C., Reimer, E., Ruthotto, L., Seif, M., Weiskopf, N., Ziegler, G. & Mohammadi, S., 2019, In : NeuroImage. 194, p. 191-210

    Research output: Contribution to journalArticle

  11. Retrospective Artifact Elimination in MEGA-PRESS using a Correlation Approach

    Tapper, S., Tisell, A., Gunther Helms & Lundberg, P., 2019, In : Magnetic Resonance in Medicine. 81, 4, p. 2223-2237 15 p.

    Research output: Contribution to journalArticle

  12. 2018
  13. Challenges in quantitative MRI

    Gunther Helms, 2018 Aug, Challenges in quantitative MRI. EFOMP European Federation of Organizations for Medical Physics, Vol. Abstracts from the 2nd European Congress of Medical Physics. p. 7-7 1 p. 7. (Physica Medica, European Journal of Medical Physics; vol. 52, no. s1).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  14. hMRI – A toolbox for using quantitative MRI in neuroscience and clinical research

    Balteau, E., Tabelow, K., Ashburner, J., Callaghan, M., Draganski, B., Gunther Helms, Kherif, F., Leutritz, T., Lutti, A., Philips, C., Reimer, E., Ruthotto, L., Seif, M., Weiskopf, N., Ziegler, G. & Mohammadi, S., 2018 Jul 31, Berlin: Weierstraß Institute for Applied Analysis and Stochastics, 35 p. (Weierstraß Institute for Applied Analysis and Stochastics Preprints).

    Research output: Working paper

  15. In vivo high field myelin water imaging: Investigating the T2 distribution at 7T

    Wiggermann, V., MacKay, A. L., Gunther Helms & Rauscher, A., 2018 Jun 1, In vivo high field myelin water imaging: Investigating the T2 distribution at 7T. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 26. 3 p. 5499. (Proceedings of the ISMRM; vol. 26).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  16. Shifted dynamic interactions between subcortical nuclei and inferior frontal gyri during response preparation in persistent developmental stuttering

    Metzger, F. L., Auer, T., Gunther Helms, Paulus, W., Frahm, J., Sommer, M. & Neef, N. E., 2018, In : Brain Structure and Function. 223, 1, p. 165-182

    Research output: Contribution to journalArticle

  17. 2016
  18. Brain metabolite changes in patients with relapsing-remitting and secondary progressive Multiple Sclerosis: a two-year follow-up study

    Obert, D., Gunther Helms, Sättler, M. B., Jung, K., Kretzschmar, B., Bähr, M., Dechent, P., Diem, R. & Hein, K., 2016 Sep 16, In : PLoS ONE. 11, 9, e0162583.

    Research output: Contribution to journalArticle

  19. Embodied neurology: an integrative framework for neurological disorders

    Freund, P., Friston, K., Thompson, A. J., Stephan, K. E., Ashburner, J., Bach, D. R., Nagy, Z., Gunther Helms, Draganski, B., Mohammadi, S., Schwab, M. E., Curt, A. & Weiskopf, N., 2016 Jun, In : Brain. 139, p. 1855-1861 7 p.

    Research output: Contribution to journalArticle

  20. A new targeted model of experimental autoimmune encephalomyelitis in the common marmoset

    Stassart, R. M., Gunther Helms, Garea-Rodriguez, E., Nessler, S., Hayardeny, L., Wegner, C., Schlumbohm, C., Fuchs, E. & Brück, W., 2016, In : Brain Pathology. 26, 4, p. 452-464

    Research output: Contribution to journalArticle

  21. Comparative analysis of the effects of neurotrophic factors CDNF and GDNF in a nonhuman primate model of Parkinson’s disease

    Garea-Rodríguez, E., Eesmaa, A., Lindholm, P. K., Schlumbohm, C., König, J., Meller, B., Krieglstein, K., Gunther Helms, Saarma, M. & Fuchs, E., 2016, In : PLoS ONE. 11, 2, p. 1-21

    Research output: Contribution to journalArticle

  22. Neurobiological origin of spurious brain morphological changes: A quantitative MRI study

    Lorio, S., Kherif, F., Ruef, A., Melie-Garcia, L., Frackowiak, R. S. J., Ashburner, J., Gunther Helms, Lutti, A. & Draganski, B., 2016, In : Human Brain Mapping. 37, 5, p. 1801-1815

    Research output: Contribution to journalArticle

  23. New tissue priors for improved automated classification of subcortical brain structures on MRI.

    Lorio, S., Fresard, S., Adaszewski, S., Kherif, F., Chowdhury, R., Frackowiak, R. S., Ashburner, J., Gunther Helms, Weiskopf, N., Lutti, A. & Draganski, B., 2016, In : NeuroImage. 130, p. 157-166

    Research output: Contribution to journalArticle

  24. Pharmacokinetics of the MRI contrast agent gadobutrol in common marmoset monkeys (Callithrix jacchus)

    Gunther Helms, Schlumbohm, C., Garea-Rodriguez, E., Dechent, P. & Fuchs, E., 2016, In : Journal of Medical Primatology. 45, 6, p. 290-296 7 p.

    Research output: Contribution to journalArticle

  25. Segmentation of human brain using structural MRI

    Gunther Helms, 2016, In : Magma. 29, 2

    Research output: Contribution to journalReview article

  26. 2015
  27. Correction for Residual Effects of B1+ Inhomogeniety on MT Saturation in FLASH-Based Multi-Parameter Mapping of the Brain

    Gunther Helms, 2015 May 30, Proceedings of the International Society for Magnetic Resonance in Medicine Annual Meeting 2015. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 23. p. 3360 1 p. 3360. (Proceedings of the ISMRM; vol. 23).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  28. Excretion Rate and Distribution Volumes in Common Marmoset Monkeys After Slow and Fast Injection of Gadobutrol

    Gunther Helms, Schlumbohm, C., Garea Rodriguez, E. & Fuchs, E., 2015 May 30, Proceedings of the International Society for Magnetic Resonance in Medicine Annual Meeting 2015. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 23. 1 p. 3273. (Proceedings of the ISMRM; vol. 23).

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  29. Tissue Properties from Quantitative MRI

    Gunther Helms, 2015, Brain Mapping: An Encyclopedic Reference. Toga, A. W. (ed.). Elsevier, Vol. 1. p. 287-294

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  30. 2014
  31. A general linear relaxometry model of R1 using imaging data

    Callaghan, M. F., Gunther Helms, Lutti, A., Mohammadi, S. & Weiskopf, N., 2014, In : Magnetic Resonance in Medicine. 73, 3, p. 1309-1314

    Research output: Contribution to journalArticle

  32. Brain issue properties differentiate between motor and limbic basal ganglia circuits

    Accolla, E. A., Dukart, J., Gunther Helms, Weiskopf, N., Kherif, F., Lutti, A., Hetzer, S., Haynes, J-D., Kühn, A. A. & Draganski, B., 2014, In : Human Brain Mapping. 35, 10, p. 5083-5092

    Research output: Contribution to journalArticle

  33. Disentangling in vivo the effects of iron content and atrophy on the ageing human brain

    Lorio, S., Lutti, A., Kherif, F., Ruef, A., Dukart, J., Chowdhury, R., Frackowiak, R. S. J., Ashburner, J., Gunther Helms, Weiskopf, N. & Draganski, B., 2014, In : NeuroImage. 103, p. 280-289

    Research output: Contribution to journalArticle

  34. Idiopathic generalized epilepsy shows profound white matter diffusion-tensor imaging alterations

    Focke, N. K., Diederich, C., Gunther Helms, Nitsche, M. A. & Paulus, W., 2014, In : Human Brain Mapping. 35, 7, p. 3332-3342

    Research output: Contribution to journalArticle

  35. MRT-Untersuchung des Erhaltungszustandes der historischen Göttinger Gehirnpräparate

    Gunther Helms, 2014, In : Mitteilungen. 51, p. 33-38

    Research output: Contribution to journalArticle

  36. Reproducibility of the structural brain connectome derived from diffusion tensor imaging

    Bonilha, L., Gleichgerrcht, E., Fridriksson, J., Rorden, C., Breedlove, J. L., Nesland, T., Paulus, W., Gunther Helms & Focke, N. K., 2014, In : PLoS ONE. 10, 8, p. e0135247-e0135247

    Research output: Contribution to journalArticle

  37. Structural abnormalities in the thalamus of migraineurs with aura: a multiparametric study at 3T

    Granziera, C., Daducci, A., Roche, A., Romascano, D., Gunther Helms, Krueger, G. & Hadjikhani, N., 2014, In : Human Brain Mapping. 35, 4, p. 1461-1468

    Research output: Contribution to journalArticle

  38. Wide-spread age-related differences in human brain microstructure revealed by quantitative MRI

    Callaghan, M. F., Freund, P., Draganski, B., Anderson, E., Cappelletti, M., Chowdhury, R., Diedrichsen, J., Fitzgerald, T. H. B., Smittenaar, P., Gunther Helms, Lutti, A. & Weiskopf, N., 2014, In : Neurobiology of Aging. 35, 8, p. 1862-1872

    Research output: Contribution to journalArticle

  39. 2013
  40. Therapy Effects in Cerebral Folate Transport Deficiency with Hypomyelination Monitored by Multimodal Quantitative MR-Imaging

    Dreha-Kulaczewski, S. F., Steinfeld, R., Brockmann, K., Dechent, P., Gärtner, J. & Gunther Helms, 2013 Apr, In : Proceedings of the International Society for Magnetic Resonance in Medicine. 21, p. 1080

    Research output: Contribution to journalPublished meeting abstract

  41. A novel SLC6A8 mutation in a large family with X-linked intellectual disability: clinical and proton magnetic resonance spectroscopy data of both hemizygous males and heterozygous females

    Dreha-Kulaczewski, SF., Kalscheuer, V., Tzschach, A., Hu, HC., Gunther Helms, Brockmann, K., Weddige, A., Dechent, P., Schlueter, G., Kraetzner, R., Ropers, H-H., Gaertner, J. & Zirn, B., 2013, JIMD Reports - Case and Research Reports. Springer, Vol. 13. p. 91-99

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  42. Increased growth of colorectal liver metastasis following partial hepatectomy

    Krause, P., Flikweert, H., Monin, M., Seif Amir Hosseini, A., Gunther Helms, Cantanhede, G., Ghadimi, BM. & Koenig, S., 2013, In : Clinical and Experimental Metastasis. 30, 5, p. 681-693

    Research output: Contribution to journalArticle

  43. Multiparametric brainstem segmentation using a modified multivariate mixture of gaussians

    Lambert, C., Lutti, A., Gunther Helms, Frackowiak, R. S. J. & Ashburner, J., 2013, In : NeuroImage: Clinical. 16, 2, p. 684-94

    Research output: Contribution to journalArticle

  44. Structural and quantitative neuroimaging of the common marmoset monkey using a clinical MRI system

    Gunther Helms, Garea-Rodriguez, E., Schlumbohm, C., König, J., Dechent, P., Fuchs, E. & Wilke, M., 2013, In : Journal of Neuroscience Methods. 215, 1, p. 121-131

    Research output: Contribution to journalArticle

  45. 2012
  46. Resampling strategies in quantitative single voxel MRS

    Gunther Helms, 2012 Apr 13, Proceedings of Data Acquisition and Evaluation Methods in Proton MR Spectroscopy 2011. Klose, U. (ed.). Aachen: Shaker Verlag, p. 41-52 12 p.

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  47. Assessment of myelination in hypomyelinating disorders by quantitative MRI

    Dreha-Kulaczewski, S. F., Brockmann, K., Henneke, M., Dechent, P., Gärtner, J. & Gunther Helms, 2012, In : Journal of Magnetic Resonance Imaging. 36, 6, p. 1329-38

    Research output: Contribution to journalArticle

  48. Visualizing dopamine transporter integrity with iodine-123 FP-CIT SPECT in combination with high resolution MRI in the brain of the common marmoset monkey

    Garea-Rodríguez, E., Schlumbohm, C., Czéh, B., König, J., Gunther Helms, Heckmann, C., Meller, B., Meller, J. & Fuchs, E., 2012, In : Journal of Neuroscience Methods. 210, 2, p. 195-201

    Research output: Contribution to journalArticle

  49. 2011
  50. Basal cerebral blood volume during the poststimulation undershoot in BOLD MRI of the human brain

    Dechent, P., Schuetze, G., Gunther Helms, Merboldt, K-D. & Frahm, J., 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 1, p. 82-89

    Research output: Contribution to journalArticle

  51. Differentiation of typical and atypical Parkinson syndromes by quantitative MR imaging

    Focke, N. K., Gunther Helms, Pantel, P. M., Scheewe, S., Knauth, M., Bachmann, C. G., Ebentheuer, J., Dechent, P., Paulus, W. & Trenkwalder, C., 2011, In : AJNR. American journal of neuroradiology. 32, 11, p. 2087-92

    Research output: Contribution to journalArticle

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