Håkan Axelson

Professor
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  1. 2018
  2. Tracing Renal Cell Carcinomas back to the Nephron

    David Lindgren, Jonas Sjölund & Håkan Axelson, 2018 Jul, In : Trends in Cancer . 4, 7, p. 472-484

    Research output: Contribution to journalArticle

  3. Patient-derived xenograft models reveal intratumor heterogeneity and temporal stability in neuroblastoma

    Braekeveldt, N., Von Stedingk, K., Fransson, S., Martinez-Monleon, A., Lindgren, D., Axelson, H., Levander, F., Willforss, J., Hansson, K., Øra, I., Backman, T., Börjesson, A., Beckman, S., Esfandyari, J., Berbegall, A. P., Noguera, R., Karlsson, J., Koster, J., Martinsson, T., Gisselsson, D. & 2 othersSven Påhlman & Daniel Bexell, 2018, In : Cancer Research. 78, 20, p. 5958-5969 12 p.

    Research output: Contribution to journalArticle

  4. 2017
  5. 2016
  6. 2015
  7. Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use.

    Kristoffer von Stedingk, De Preter, K., Vandesompele, J., Noguera, R., Ingrid Øra, Koster, J., Versteeg, R., Sven Påhlman, David Lindgren & Håkan Axelson, 2015, In : International Journal of Cancer. 137, 4, p. 868-877

    Research output: Contribution to journalArticle

  8. The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels.

    Fritz, H., Gustafsson, A., Ljungberg, B., Yvonne Ceder, Håkan Axelson & Björn Dahlbäck, 2015, In : PLoS ONE. 10, 8, e0135991.

    Research output: Contribution to journalArticle

  9. 2014
  10. Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

    Rankin, E. B., Fuh, K. C., Castellini, L., Viswanathan, K., Finger, E. C., Diep, A. N., LaGory, E. L., Kariolis, M. S., Chan, A., David Lindgren, Håkan Axelson, Miao, Y. R., Krieg, A. J. & Giaccia, A. J., 2014, In : Proceedings of the National Academy of Sciences. 111, 37, p. 13373-13378

    Research output: Contribution to journalArticle

  11. Epithelial and Stromal MicroRNA Signatures of Columnar Cell Hyperplasia Linking Let-7c to Precancerous and Cancerous Breast Cancer Cell Proliferation.

    Björner, S., Fitzpatrick, P. A., Li, Y., Allred, C., Howell, A., Anita Ringberg, Håkan Olsson, Miller, C. J., Håkan Axelson & Landberg, G., 2014, In : PLoS ONE. 9, 8, e105099.

    Research output: Contribution to journalArticle

  12. Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney.

    Jennifer Hansson, Hultenby, K., Cramnert, C., Pontén, F., Jansson, H., David Lindgren, Håkan Axelson & Martin Johansson, 2014, In : Human Pathology. 45, 2, p. 382-393

    Research output: Contribution to journalArticle

  13. The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

    Fritz, H., David Lindgren, Ljungberg, B., Håkan Axelson & Björn Dahlbäck, 2014, In : European Journal of Cancer. 50, 10, p. 1758-1765

    Research output: Contribution to journalArticle

  14. 2013
  15. Kidney cancer.

    Martin Johansson & Håkan Axelson, 2013, In : Seminars in Cancer Biology. 23, 1, p. 1-2

    Research output: Contribution to journalDebate/Note/Editorial

  16. Renal stem cells and their implications for kidney cancer.

    Håkan Axelson & Johansson, M. E., 2013, In : Seminars in Cancer Biology. 23, 1, p. 56-61

    Research output: Contribution to journalReview article

  17. snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.

    Kristoffer von Stedingk, Koster, J., Piqueras, M., Noguera, R., Navarro, S., Sven Påhlman, Versteeg, R., Ingrid Øra, David Gisselsson Nord, David Lindgren & Håkan Axelson, 2013, In : Translational Oncology. 6, 4, p. 447-U142

    Research output: Contribution to journalArticle

  18. 2012
  19. 2011
  20. Isolation and characterization of progenitor-like cells from human renal proximal tubules.

    David Lindgren, Boström, A-K., Nilsson, K., Jennifer Hansson, Jonas Sjölund, Christina Möller, Karin Jirström, Nilsson, E., Landberg, G., Håkan Axelson & Martin Johansson, 2011, In : American Journal of Pathology. 178, 2, p. 828-837

    Research output: Contribution to journalArticle

  21. The Notch and TGF-beta Signaling Pathways Contribute to the Aggressiveness of Clear Cell Renal Cell Carcinoma.

    Jonas Sjölund, Boström, A-K., David Lindgren, Manna, S., Moustakas, A., Ljungberg, B., Johansson, M., Fredlund, E. & Håkan Axelson, 2011, In : PLoS ONE. 6, 8, e23057.

    Research output: Contribution to journalArticle

  22. 2010
  23. The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma

    Mestdagh, P., Boström, A-K., Impens, F., Fredlund, E., Van Peer, G., De Antonellis, P., Kristoffer von Stedingk, Ghesquiere, B., Schulte, S., Dews, M., Thomas-Tikhonenko, A., Schulte, J. H., Zollo, M., Schramm, A., Gevaert, K., Håkan Axelson, Speleman, F. & Vandesompele, J., 2010, In : Molecular Cell. 40, 5, p. 762-773

    Research output: Contribution to journalArticle

  24. 2009
  25. CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney

    Nyström, J., Hultenby, K., Sara Ek, Jonas Sjölund, Håkan Axelson, Karin Jirström, Saleem, M., Nilsson, K. & Martin Johansson, 2009, In : Nephrology Dialysis Transplantation. 24, 7, p. 2038-2044

    Research output: Contribution to journalArticle

  26. Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma.

    Gustafsson, A., Boström, A-K., Ljungberg, B., Håkan Axelson & Björn Dahlbäck, 2009, In : PLoS ONE. 4, 10, e7575.

    Research output: Contribution to journalArticle

  27. HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.

    Löfstedt, T., Fredlund, E., Noguera, R., Navarro, S., Linda Holmquist Mengelbier, Beckman, S., Sven Påhlman & Håkan Axelson, 2009, In : Experimental Cell Research. 315, 11, p. 1924-1936

    Research output: Contribution to journalArticle

  28. 2008
  29. Impaired Function of Hematopoietic Stem Cells with Abrogated Hypoxia Induced Expression of Vascular Endothelial Growth Factor

    Rehn, M., Reckzeh, K., Olsson, A., Håkan Axelson & Cammenga, J., 2008, In : Blood. 112, 11, p. 110-110

    Research output: Contribution to journalPublished meeting abstract

  30. Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

    Jonas Sjölund, Martin Johansson, Manna, S., Norin, C., Alexander Pietras, Beckman, S., Nilsson, E., Ljungberg, B. & Håkan Axelson, 2008, In : Journal of Clinical Investigation. 118, 1, p. 217-228

    Research output: Contribution to journalArticle

  31. 2007
  32. The Lim-only protein LMO2 acts as a positive regulator of erythroid differentiation

    Hansson, A., Zetterblad, J., van Duren, C., Håkan Axelson & Jönsson, J-I., 2007, In : Biochemical and Biophysical Research Communications. 364, 3, p. 675-681

    Research output: Contribution to journalArticle

  33. 2006
  34. Eyeing tumorigenesis: Notch signaling and epigenetic silencing of Rb in Drosophila.

    Håkan Axelson, 2006, In : BioEssays. 28, 7, p. 692-695

    Research output: Contribution to journalArticle

  35. 2005
  36. Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells.

    Stockhausen, M., Jonas Sjölund, Manetopoulos, C. & Håkan Axelson, 2005, In : British Journal of Cancer. 92, 4, p. 751-759

    Research output: Contribution to journalArticle

  37. Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors.

    Håkan Axelson, Fredlund, E., Ovenberger, M., Landberg, G. & Sven Påhlman, 2005, In : Seminars in Cell & Developmental Biology. 16, 4-5, p. 554-563

    Research output: Contribution to journalReview article

  38. Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development

    Emma Smith, Akerblad, P., Kadesch, T., Håkan Axelson & Mikael Sigvardsson, 2005, In : Blood. 106, 6, p. 1995-2001

    Research output: Contribution to journalArticle

  39. The Notch pathway in cancer: Differentiation gone awry.

    Jonas Sjölund, Manetopoulos, C., Stockhausen, M. & Håkan Axelson, 2005, In : European Journal of Cancer. 41, p. 2620-2629

    Research output: Contribution to journalReview article

  40. 2004
  41. Expression and DNA-binding activity of MYCN/Max and Mnt/Max during induced differentiation of human neuroblastoma cells.

    Smith, A. G., Popov, N., Imreh, M., Håkan Axelson & Henriksson, M., 2004, In : Journal of Cellular Biochemistry. 92, 6, p. 1282-1295

    Research output: Contribution to journalArticle

  42. Induction of ID2 expression by hypoxia-inducible factor-1: ARole in dedifferentiation of hypoxic neuroblastoma cells.

    Löfstedt, T., Annika Jögi, Mikael Sigvardsson, Gradin, K., Poellinger, L., Sven Påhlman & Håkan Axelson, 2004, In : Journal of Biological Chemistry. 279, 38, p. 39223-39231

    Research output: Contribution to journalArticle

  43. Notch signaling and cancer: emerging complexity.

    Håkan Axelson, 2004, In : Seminars in Cancer Biology. 14, 5, p. 317-319

    Research output: Contribution to journalLetter

  44. Notch signaling in neuroblastoma.

    Sven Påhlman, Stockhausen, M., Fredlund, E. & Håkan Axelson, 2004, In : Seminars in Cancer Biology. 14, 5, p. 365-373

    Research output: Contribution to journalArticle

  45. Olf/EBF proteins are expressed in neuroblastoma cells: potential regulators of the Chromogranin A and SCG10 promoters.

    Persson, P., Manetopoulos, C., Lagergren, A., Nygren, J., Gisler, R., Håkan Axelson & Mikael Sigvardsson, 2004, In : International Journal of Cancer. 110, 1, p. 22-30

    Research output: Contribution to journalArticle

  46. 2003
  47. Hypoxia-induced dedifferentiation in neuroblastoma cells.

    Annika Jögi, Ingrid Øra, Helén Nilsson, Poellinger, L., Håkan Axelson & Sven Påhlman, 2003, In : Cancer Letters. 197, 1-2, p. 145-150

    Research output: Contribution to journalArticle

  48. ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value

    Vandesompele, J., Edsjö, A., De Preter, K., Håkan Axelson, Speleman, F. & Sven Påhlman, 2003, In : Oncogene. 22, 3, p. 456-460

    Research output: Contribution to journalArticle

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