Hakon Leffler

Senior Professor
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  1. 2021
  2. Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis

    Nikhil Hirani, Alison C. MacKinnon, Lisa Nicol, Paul Ford, Hans Schambye, Anders Pedersen, Ulf J. Nilsson, Hakon Leffler, Tariq Sethi, Susan Tantawi, Lise Gravelle, Robert J. Slack, Ross Mills, Utsa Karmakar, Duncan Humphries, Fredrik Zetterberg, Lucy Keeling, Lyn Paul, Philip L. Molyneaux, Feng Li & 5 others, Wendy Funston, Ian A. Forrest, A. John Simpson, Michael A. Gibbons & Toby M. Maher, 2021 May 1, In: European Respiratory Journal. 57, 5, 2002559.

    Research output: Contribution to journalArticle

  3. Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression

    Seok Jun Kim, Hyeok Gu Kang, Kyungeun Kim, Hoyoung Kim, Fredrik Zetterberg, Young Soo Park, Hyun Soo Cho, Stephen M. Hewitt, Joon Yong Chung, Ulf J. Nilsson, Hakon Leffler & Kyung Hee Chun, 2021, In: Gastric Cancer.

    Research output: Contribution to journalArticle

  4. Synthesis and Biological Studies of O3-Aryl Galactosides as Galectin Inhibitors

    Gabriella Kervefors, Kumar Bhaskar Pal, Gergely L. Tolnai, Mukul Mahanti, Hakon Leffler, Ulf J. Nilsson & Berit Olofsson, 2021, In: Helvetica Chimica Acta. 104, 2

    Research output: Contribution to journalArticle

  5. 2020
  6. Epimers Switch Galectin-9 Domain Selectivity: 3 N-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal

    Mukul Mahanti, Kumar Bhaskar Pal, Anders P. Sundin, Hakon Leffler & Ulf J. Nilsson, 2020, In: ACS Medicinal Chemistry Letters. 11, 1, p. 34-39

    Research output: Contribution to journalArticle

  7. In Vivo Veritas: 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors

    Klas Bratteby, Edvard Torkelsson, Elina Tampio L'Estrade, Kristoffer Peterson, Vladimir Shalgunov, Mengfei Xiong, Hakon Leffler, Fredrik R. Zetterberg, Tomas G. Olsson, Nic Gillings, Ulf J. Nilsson, Matthias M. Herth & Maria Erlandsson, 2020, In: Journal of Medicinal Chemistry. 63, 2, p. 747-755 9 p.

    Research output: Contribution to journalArticle

  8. 2019
  9. 3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3

    Alexander Dahlqvist, Santanu Mandal, Kristoffer Peterson, Maria Håkansson, Derek T. Logan, Fredrik R. Zetterberg, Hakon Leffler & Ulf J. Nilsson, 2019 Dec 12, In: Molecules. 24, 24, 4554.

    Research output: Contribution to journalArticle

  10. Extracellular and intracellular small-molecule galectin-3 inhibitors

    John Stegmayr, Fredrik Zetterberg, Michael C. Carlsson, Xiaoli Huang, Gunjan Sharma, Barbro Kahl-Knutson, Hans Schambye, Ulf J. Nilsson, Stina Oredsson & Hakon Leffler, 2019 Feb 18, In: Scientific Reports. 9, 1, 2186.

    Research output: Contribution to journalArticle

  11. Human trophoblast requires galectin-3 for cell migration and invasion

    Bojić-Trbojević, M. Jovanović Krivokuća, A. Vilotić, N. Kolundžić, I. Stefanoska, F. Zetterberg, U. J. Nilsson, H. Leffler & Lj Vićovac, 2019 Feb 14, In: Scientific Reports. 9, 1, 2136.

    Research output: Contribution to journalArticle

  12. Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects

    Rohit Kumar, Kristoffer Peterson, Majda Misini Ignjatović, Hakon Leffler, Ulf Ryde, Ulf J. Nilsson & Derek T. Logan, 2019 Jan 1, In: Organic and Biomolecular Chemistry. 17, 5, p. 1081-1089 9 p.

    Research output: Contribution to journalArticle

  13. Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors

    Alexander Dahlqvist, Fredrik R. Zetterberg, Hakon Leffler & Ulf J. Nilsson, 2019, In: MedChemComm. 10, 6, p. 913-925 13 p.

    Research output: Contribution to journalArticle

  14. An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade

    Lynda Vuong, Eleni Kouverianou, Claire M. Rooney, Brian J. McHugh, Sarah E.M. Howie, Christopher D. Gregory, Stuart J. Forbes, Neil C. Henderson, Fredrik R. Zetterberg, Ulf J. Nilsson, Hakon Leffler, Paul Ford, Anders Pedersen, Lise Gravelle, Susan Tantawi, Hans Schambye, Tariq Sethi & Alison C. MacKinnon, 2019, In: Cancer Research. 79, 7, p. 1480-1492 13 p.

    Research output: Contribution to journalArticle

  15. C1-Galactopyranosyl Heterocycle Structure Guides Selectivity: Triazoles Prefer Galectin-1 and Oxazoles Prefer Galectin-3

    Alexander Dahlqvist, Hakon Leffler & Ulf J. Nilsson, 2019, In: ACS Omega. 4, 4, p. 7047-7053 7 p.

    Research output: Contribution to journalArticle

  16. Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

    Antonio Boza-Serrano, Rocío Ruiz, Raquel Sanchez-Varo, Juan García-Revilla, Yiyi Yang, Itzia Jimenez-Ferrer, Agnes Paulus, Malin Wennström, Anna Vilalta, David Allendorf, Jose Carlos Davila, John Stegmayr, Sebastian Jiménez, Maria A. Roca-Ceballos, Victoria Navarro-Garrido, Maria Swanberg, Christine L. Hsieh, Luis M. Real, Elisabet Englund, Sara Linse & 7 others, Hakon Leffler, Ulf J. Nilsson, Guy C. Brown, Antonia Gutierrez, Javier Vitorica, Jose Luis Venero & Tomas Deierborg, 2019, In: Acta Neuropathologica. 138, 2, p. 251-273

    Research output: Contribution to journalArticle

  17. Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

    Maria Luisa Verteramo, Olof Stenström, Majda Misini Ignjatović, Octav Caldararu, Martin A. Olsson, Francesco Manzoni, Hakon Leffler, Esko Oksanen, Derek T. Logan, Ulf J. Nilsson, Ulf Ryde & Mikael Akke, 2019, In: Journal of the American Chemical Society. 141, 5, p. 2012–2026

    Research output: Contribution to journalArticle

  18. Structure and Energetics of Ligand–Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions

    Rohit Kumar, Majda Misini Ignjatović, Kristoffer Peterson, Martin Olsson, Hakon Leffler, Ulf Ryde, Ulf J. Nilsson & Derek T. Logan, 2019, In: ChemMedChem. 14, 16, p. 1528-1536 9 p.

    Research output: Contribution to journalArticle

  19. 2018
  20. Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain

    Kumar Bhaskar Pal, Mukul Mahanti, Xiaoli Huang, Stella Persson, Anders P. Sundin, Fredrik R. Zetterberg, Stina Oredsson, Hakon Leffler & Ulf J. Nilsson, 2018 Aug 3, In: Organic and Biomolecular Chemistry. 16, 34, p. 6295-6305 11 p.

    Research output: Contribution to journalArticle

  21. Different angioregulatory activity of monovalent galectin-9 isoforms

    Ed Aanhane, Iris A. Schulkens, Roy Heusschen, Kitty Castricum, Hakon Leffler, Arjan W. Griffioen & Victor L. Thijssen, 2018 Aug, In: Angiogenesis. 21, 3, p. 545-555

    Research output: Contribution to journalArticle

  22. The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin

    Xiaoli Huang, Björn Borgström, John Stegmayr, Yasmin Abassi, Monika Kruszyk, Hakon Leffler, Lo Persson, Sebastian Albinsson, Ramin Massoumi, Ivan G. Scheblykin, Cecilia Hegardt, Stina Oredsson & Daniel Strand, 2018 Jun 27, In: ACS Central Science. 4, 6, p. 760-767 8 p.

    Research output: Contribution to journalArticle

  23. Galectins at a glance

    Ludger Johannes, Ralf Jacob & Hakon Leffler, 2018 May 1, In: Journal of Cell Science. 131, 9, jcs208884.

    Research output: Contribution to journalArticle

  24. Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

    Kristoffer Peterson, Rohit Kumar, Olof Stenström, Priya Verma, Prashant R. Verma, Maria Håkansson, Barbro Kahl-Knutsson, Fredrik Zetterberg, Hakon Leffler, Mikael Akke, Derek T. Logan & Ulf J. Nilsson, 2018 Feb 8, In: Journal of Medicinal Chemistry. 61, 3, p. 1164-1175 12 p.

    Research output: Contribution to journalArticle

  25. Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function

    Martina Sundqvist, Amanda Welin, Jonas Elmwall, Veronica Osla, Ulf J. Nilsson, Hakon Leffler, Johan Bylund & Anna Karlsson, 2018 Feb, In: Journal of Leukocyte Biology. 103, 2, p. 341-353

    Research output: Contribution to journalArticle

  26. Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions

    Fredrik R. Zetterberg, Kristoffer Peterson, Richard E. Johnsson, Thomas Brimert, Maria Håkansson, Derek T. Logan, Hakon Leffler & Ulf J. Nilsson, 2018 Jan 22, In: ChemMedChem. 13, 2, p. 133-137

    Research output: Contribution to journalArticle

  27. Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands

    Kristoffer Peterson, Patrick M. Collins, Xiaoli Huang, Barbro Kahl-Knutsson, Sofia Essén, Fredrik R. Zetterberg, Stina Oredsson, Hakon Leffler, Helen Blanchard & Ulf J. Nilsson, 2018, In: RSC Advances. 8, 44, p. 24913-24922 10 p.

    Research output: Contribution to journalArticle

  28. Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin–glycan specificities in a natural context

    Mathias Ingemann Nielsen, John Stegmayr, Oliver C. Grant, Zhang Yang, Ulf J. Nilsson, Irene Boos, Michael C. Carlsson, Robert J. Woods, Carlo Unverzagt, Hakon Leffler & Hans H. Wandall, 2018, In: Journal of Biological Chemistry. 293, 52, p. 20249-20262 14 p.

    Research output: Contribution to journalArticle

  29. 2017
  30. Spindle pole cohesion requires glycosylation-mediated localization of NuMA

    Jérémy Magescas, Lucie Sengmanivong, Amandine Viau, Adeline Mayeux, Tien Dang, Martine Burtin, Ulf Nilsson, Hakon Leffler, Françoise Poirier, Fabiola Terzi & Delphine Delacour, 2017 Dec 1, In: Scientific Reports. 7, 1, 1474.

    Research output: Contribution to journalArticle

  31. Galectin-3 inhibition by a small-molecule inhibitor reduces both pathological corneal neovascularization and fibrosis

    Wei Sheng Chen, Zhiyi Cao, Hakon Leffler, Ulf J. Nilsson & Noorjahan Panjwani, 2017 Jan 1, In: Investigative Ophthalmology and Visual Science. 58, 1, p. 9-20 12 p.

    Research output: Contribution to journalArticle

  32. 2016
  33. Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C

    Francesco Manzoni, Saraboji Kadhirvel, Janina Sprenger, Rohit Kumar, Ann Louise Noresson, Ulf J. Nilsson, Hakon Leffler, S. Zoë Fisher, Tobias E. Schrader, Andreas Ostermann, Leighton Coates, Matthew P. Blakeley, Esko Oksanen & Derek T. Logan, 2016 Nov 1, In: Acta Crystallographica Section D: Structural Biology. 72, 11, p. 1194-1202 9 p.

    Research output: Contribution to journalArticle

  34. A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

    Vishal Kumar Rajput, Alison MacKinnon, Santanu Mandal, Patrick Collins, Helen Blanchard, Hakon Leffler, Tariq Sethi, Hans Schambye, Balaram Mukhopadhyay & Ulf J. Nilsson, 2016 Sep 8, In: Journal of Medicinal Chemistry. 59, 17, p. 8141-8147 7 p.

    Research output: Contribution to journalArticle

  35. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3

    Wei Sheng Chen, Zhiyi Cao, Satoshi Sugaya, Maria J. Lopez, Victor G. Sendra, Nora Laver, Hakon Leffler, Ulf J. Nilsson, Jianxin Fu, Jianhua Song, Lijun Xia, Pedram Hamrah & Noorjahan Panjwani, 2016 Apr 12, In: Nature Communications. 7, 11302.

    Research output: Contribution to journalArticle

  36. Galactose-amidine derivatives as selective antagonists of galectin-9

    Santanu Mandal, Vishal Kumar Rajput, Anders P. Sundin, Hakon Leffler, Balaram Mukhopadhyay & Ulf J. Nilsson, 2016 Feb 4, In: Canadian Journal of Chemistry. 94, 11, p. 936-939 4 p.

    Research output: Contribution to journalArticle

  37. Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

    Tamara Delaine, Patrick Collins, Alison Mackinnon, G. Sharma, John Stegmayr, Vishal K. Rajput, Santanu Mandal, Ian Cumpstey, Amaia Larumbe, Bader A. Salameh, Barbro Kahl Knutson, Hilde vanHattum, Monique van Scherpenzeel, Roland J. Pieters, Tariq Sethi, Hans Schambye, Stina Oredsson, Hakon Leffler, Helen Blanchard & Ulf Nilsson, 2016, In: ChemBioChem. 17, 18, p. 1759-1770

    Research output: Contribution to journalArticle

  38. Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis.

    Mattias Block, Johan Mölne, Hakon Leffler, Lars Börjesson & Michael E Breimer, 2016, In: BioMed Research International. 2016, 5989128.

    Research output: Contribution to journalArticle

  39. Intra- and inter-molecular interactions of human galectin-3: assessment by full-assignment-based NMR.

    Hans Ippel, Michelle C Miller, Sabine Vértesy, Yi Zhang, F Javier Cañada, Dennis Suylen, Kimiko Umemoto, Cecilia Romanò, Tilman Hackeng, Guihua Tai, Hakon Leffler, Jürgen Kopitz, Sabine André, Dieter Kübler, Jesús Jiménez-Barbero, Stefan Oscarson, Hans-Joachim Gabius & Kevin H Mayo, 2016, In: Glycobiology. 26, 8, p. 888-903 16 p.

    Research output: Contribution to journalArticle

  40. Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans

    John Stegmayr, Adriana Lepur, Barbro Kahl Knutson, Matilde Aguilar-Moncayo, Anatole A. Klyosov, Robert A. Field, Stina Oredsson, Ulf Nilsson & Hakon Leffler, 2016, In: Journal of Biological Chemistry. 291, 25, p. 13318-13334 17 p.

    Research output: Contribution to journalArticle

  41. 2015
  42. Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury

    Vladislav Volarevic, Bojana Simovic Markovic, Sanja Bojic, Maja Stojanovic, Ulf Nilsson, Hakon Leffler, Gurdyal S. Besra, Nebojsa Arsenijevic, Verica Paunovic, Vladimir Trajkovic & Miodrag L. Lukic, 2015, In: European Journal of Immunology. 45, 2, p. 531-543

    Research output: Contribution to journalArticle

  43. Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

    Miguel Burguillos Garcia, Martina Svensson, Tim Schulte, Antonio Boza Serrano, Albert Garcia-Quintanilla, Edel Kavanagh, Martiniano Santiago, Nikenza Viceconte, Maria Jose Oliva-Martin, Ahmed Mohamed Osman, Emma Salomonsson, Lahouari Amar, Annette Persson, Klas Blomgren, Adnane Achour, Elisabet Englund, Hakon Leffler, Jose Luis Venero, Bertrand Joseph & Tomas Deierborg, 2015, In: Cell Reports. 10, 9, p. 1626-1638

    Research output: Contribution to journalArticle

  44. 2014
  45. Primary and secondary glomerulonephritides 1.

    Ian Proletov, Vasilii Sipovskii, Alexei Smirnov, Norifumi Hayashi, Shin'Ichi Akiyama, Hiroshi Okuyama, Yuki Matsui, Keiji Fujimoto, Hirokatsu Atsumi, Hiroki Adachi, Hideki Yamaya, Shoichi Maruyama, Enyu Imai, Seiichi Matsuo, Hitoshi Yokoyama, Narayan Prasad, Akhilesh Jaiswal, Vikas Agarwal, Brijesh Yadav, Mohit Rai & 298 others, Dong Ho Shin, In Mi Han, Sung Jin Moon, Tae-Hyun Yoo, Bernardo Faria, Carla Henriques, Ana C Matos, Mohamed R Daha, Manuel Pestana, Marc Seelen, Sigrid Lundberg, Michael Carlsson, Hakon Leffler, Peter Påhlsson, Mårten Segelmark, Roberta Camilla, Maria Elena Donadio, Elisa Loiacono, Licia Peruzzi, Alessandro Amore, Federica Chiale, Luca Vergano, Rachele Gallo, Alberto Boido, Margherita Conrieri, Manuela Bianciotto, Francesca Maria Bosetti, Giulio Mengozzi, Maria Paola Puccinelli, Carla Guidi, Inna Lastauka, Rosanna Coppo, Hiroki Nishiwaki, Takeshi Hasegawa, Yoshikuni Nagayama, Daisuke Komukai, Nobuharu Kaneshima, Fumihiko Sasai, Ashio Yoshimura, Cai-Li Wang, Xiao-Yan Wei, Li Lv, Ni-Ya Jia, Ann Merethe Vågane, Thomas Knoop, Bjørn Egil Vikse, Anna Varberg Reisæter, Rune Bjørneklett, Nicoletta Mezzina, Francesca Brunini, Barbara Trezzi, Maurizio Gallieni, Marco D'Amico, Tiziana Stellato, Domenico Santoro, Gian Marco Ghiggeri, Antonella Radice, Renato Alberto Sinico, Andreas Kronbichler, Julia Kerschbaum, Gert Mayer, Michael Rudnicki, Gutierrez-Solis Elena, Caro-Espada Paula Jara, Rojas-Rivera Jorge Enrique, Praga Manuel, Jinhyuk Paek, Eunah Hwang, Sungbae Park, Yasar Caliskan, Aysun Aksoy, Nida Oztop, Yasemin Ozluk, Ayse Serra Artan, Halil Yazici, Isin Kilicaslan, Mehmet S Sever, Alaattin Yildiz, Katsuhito Ihara, Soichiro Iimori, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Sei Sasaki, Maria Stangou, Christos Bantis, Maria Skoularopoulou, George Toulkeridis, Ioanna Labropoulou, Stratis Kasimatis, Nikoleta Maria Kouri, Aikaterini Papagianni, George Efstratiadis, Gabriel Mircescu, Simona Stancu, Adrian Zugravu, Ligia Petrescu, Iuliana Andreiana, Ludmila Taran, Taihei Suzuki, Masayuki Iyoda, Yutaka Yamaguchi, Makoto Watanabe, Yukihiro Wada, Kei Matsumoto, Yuki Shindo-Hirai, Yoshihiro Kuno, Yasutaka Yamamoto, Tomohiro Saito, Ken Iseri, Takanori Shibata, Katarzyna Gniewek, Magdalena Krajewska, Katarzyna Jakuszko, Katarzyna Koscielska-Kasprzak, Marian Klinger, Ana Teresa Nunes, Inês Ferreira, Ricardo Neto, Eva Mariz, Edite Pereira, João Frazão, Augusta Praça, Susana Sampaio, Manuel Pestana, Hyung Jong Kim, Jung Eun Lee, Ian Proletov, Olga Galkina, Evdokiia Bogdanova, Irina Zubina, Vasilii Sipovskii, Alexei Smirnov, Camila Barbosa L Oliveira, Alline S A Oliveira, Clarissa Jacob B Carvalho, Luís H B C Sette, Gisele V Fernandes, Maria Alina Cavalcante, Lucila Maria Valente, Gener Ismail, Andreea Andronesi, Roxana Jurubita, Raluca Bobeica, Daniela Finocchietti, Vincenzo Cantaluppi, Davide Medica, Germana Daidola, Loredana Colla, Luca Besso, Manuel Burdese, Giuseppe Paolo Segoloni, Luigi Biancone, Giovanni Camussi, Shunsuke Goto, Kentaro Nakai, Jun Ito, Hideki Fujii, Kazuyuki Tasaki, Toshiaki Suzuki, Kei Fukami, Shigeo Hara, Shinichi Nishi, Noriko Hayami, Yoshifumi Ubara, Junichi Hoshino, Kenmei Takaichi, Tatsuya Suwabe, Kenichi Sumida, Kouki Mise, Cai-Li Wang, Yuan-Qing Tian, Hui Wang, Elena Saganova, Ian Proletov, Olga Galkina, Evdokiia Bogdanova, Irina Zubina, Vasilii Sipovskii, Alexei Smirnov, Simona Stancu, Eugen Mandache, Adrian Zugravu, Ligia Petrescu, Andreea Avram, Gabriel Mircescu, Claudio Angelini, Francesco Reggiani, Manuel A Podestà, David Cucchiari, Alberto Malesci, Salvatore Badalamenti, Mario Laganović, Elisabet Ars, Marijana Zivko, Tajana Zeljkovic Vrkić, Marijana Cˇorić, Sandra Karanović, Roser Torra, Bojan Jelaković, Ni-Ya Jia, Cai-Li Wang, Yan-Hui Zhang, Lei Nan, Yasuyuki Nagasawa, Ryohei Yamamoto, Maki Shinzawa, Sayuri Hamahata, Aritoshi Kida, Mana Yahiro, Takayuki Kuragano, Tatsuya Shoji, Terumasa Hayashi, Katsuyuki Nagatoya, Atsushi Yamauchi, Yoshitaka Isaka, Takshi Nakanishi, Vanja Ivkovic, Vedran Premuzic, Mario Laganovic, Zivka Dika, Jelena Kos, Tajana Zeljkovic Vrkic, Margareta Fistrek Prlic, Marijana Zivko, Bojan Jelakovic, Paolo Gigliotti, Francesca Leone, Danilo Lofaro, Teresa Papalia, Francesco Mollica, Agata Mollica, Donatella Vizza, Anna Perri, Renzo Bonofilgio, Guida Meneses, Helena Viana, Maria Céu Santos, Carina Ferreira, Joaquim Calado, Fernanda Carvalho, Francisco Remédio, Fernando Nolasco, Yasar Caliskan, Nida Oztop, Aysun Aksoy, Yasemin Ozluk, Ayse Serra Artan, Aydin Turkmen, Isin Kilicaslan, Alaattin Yildiz, Mehmet S Sever, Shankar Prasad Nagaraju, Srinivas Kosuru, Rajeevalochana Parthasarathy, Manohar Bairy, Ravindra Attur Prabhu, Vasudeva Guddattu, Sindhura Lakshmi Koulmane Laxminarayana, Aysegul Oruc, Mustafa Gullulu, Ebru Acikgoz, Nimet Aktas, Abdulmecit Yildiz, Bulent Gul, Vedran Premuzic, Mario Laganovic, Vanja Ivkovic, Marijana Coric, Tajana Zeljkovic Vrkic, Ljiljana Fodor, Zivka Dika, Jelena Kos, Margareta Fistrek Prlic, Marijana Zivko, Bojan Jelakovic, Charan Bhadrappa Bale, Tushar Anil Dighe, Prachi Kate, Swapnil Karnik, Atul Sajgure, Ashwini Sharma, Jayraj Korpe, Tarun Jeloka, Niranjan Ambekar, Abhay Sadre, Archana Buch, Atul Mulay, Evangelina Mérida, Ana Huerta, Eduardo Gutiérrez, Eduardo Hernández, Angel Sevillano, Jara Caro, Teresa Cavero, Enrique Morales, Jose Antonio Moreno & Manuel Praga, 2014, In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 29 Suppl 3, May, p. iii186-iii200

    Research output: Contribution to journalArticle

  46. Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists.

    Vishal Kumar Rajput, Hakon Leffler, Ulf J Nilsson & Balaram Mukhopadhyay, 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 15, p. 3516-3520

    Research output: Contribution to journalArticle

  47. Synthesis of 1,2,3-triazole-linked galactohybrids and their inhibitory activities on galectins

    Jevgenija Mackevica, Pavels Ostrovskis, Hakon Leffler, Ulf Nilsson, Vita Rudovica, Arturs Viksna, Sergey Belyakov & Maris Turksa, 2014, In: Arkivoc. 2014, 3, p. 90-112

    Research output: Contribution to journalArticle

  48. 2013
  49. Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro

    Tamara Saksida, Ivana Nikolic, Milica Vujicic, Ulf Nilsson, Hakon Leffler, Miodrag L. Lukic, Ivana Stojanovic & Stanislava Stosic-Grujicic, 2013, In: Journal of Cellular Physiology. 228, 7, p. 1568-1576

    Research output: Contribution to journalArticle

  50. Galectin-3 guides intracellular trafficking of some human serotransferrin glycoforms

    Michael Carlsson, Per Bengtson, Helena Cucak & Hakon Leffler, 2013, In: Journal of Biological Chemistry. 288, 39, p. 28398-28408

    Research output: Contribution to journalArticle

  51. Investigation into the Feasibility of Thioditaloside as a Novel Scaffold for Galectin-3-Specific Inhibitors

    Khuchtumur Bum-Erdene, Ivan A. Gagarinov, Patrick M. Collins, Moritz Winger, Andrew G. Pearson, Jennifer C. Wilson, Hakon Leffler, Ulf Nilsson, I. Darren Grice & Helen Blanchard, 2013, In: ChemBioChem. 14, 11, p. 1331-1342

    Research output: Contribution to journalArticle

  52. Tuning the Preference of Thiodigalactoside- and Lactosamine-Based Ligands to Galectin-3 over Galectin-1

    Hilde van Hattum, Hilbert M. Branderhorst, Ed E. Moret, Ulf Nilsson, Hakon Leffler & Roland J. Pieters, 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1350-1354

    Research output: Contribution to journalArticle

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