Inga-Maria Frick

Researcher

Research areas and keywords

UKÄ subject classification

  • Infectious Medicine

Research

The normal flora colonizing the skin and mucosal surfaces consists of a plethora of bacterial species of which anaerobic bacteria constitute a large group. Usually, these commensals do not breach the protective barriers of the human body, but in case of a wound or when the host becomes immuno-compromised commensals can cause infection and disease. A major member of the anaerobic commensal bacteria is the Gram-positive coccus Finegoldia magna. This bacterium is also connected with clinical infections, such as skin and deep wound infections, bone/joint infections, and is reported to be prevalent in chronic wounds. Over the last years two surface proteins expressed by the majority of F. magna isolates; the serine proteinase SufA and the adhesive FAF protein have been identified. The project involves studies on molecular interactions and mechanisms that contribute to colonization, growth and survival of these bacteria on skin and mucosal surfaces, and spread to subcutaneous tissue.

Recent research outputs

Westman, J., Chakrakodi, B., Snäll, J., Mörgelin, M., Madsen, M. B., Hyldegaard, O., Neumann, A., Inga Maria Frick, Norrby-Teglund, A., Lars Björck & Heiko Herwald, 2018 Feb 22, In : Frontiers in Immunology. 9, FEB, p. 1-14 236.

Research output: Contribution to journalArticle

Rolf Lood & Inga Maria Frick, 2017, Methods in Molecular Biology. Humana Press, Vol. 1535. p. 3-15 13 p. (Methods in Molecular Biology; vol. 1535).

Research output: Chapter in Book/Report/Conference proceedingBook chapter

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