Ingrid Hedenfalk

Senior Lecturer, Associate professor, PhD
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  1. 2019
  2. Afadin cooperates with Claudin-2 to promote breast cancer metastasis

    Tabariès, S., McNulty, A., Ouellet, V., Annis, M. G., Dessureault, M., Vinette, M., Hachem, Y., Lavoie, B., Omeroglu, A., Simon, H. G., Walsh, L. A., Siker Kimbung, Ingrid Hedenfalk & Siegel, P. M., 2019, In : Genes & Development. 33, 3-4, p. 180-193 14 p.

    Research output: Contribution to journalArticle

  3. 2018
  4. Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

    Severson, T. M., Kim, Y., Joosten, S. E. P., Schuurman, K., Van Der Groep, P., Moelans, C. B., Ter Hoeve, N. D., Manson, Q. F., Martens, J. W., Van Deurzen, C. H. M., Barbe, E., Ingrid Hedenfalk, Bult, P., Smit, V. T. H. B. M., Linn, S. C., Van Diest, P. J., Wessels, L. & Zwart, W., 2018 Dec 1, In : Nature Communications. 9, 1, 482.

    Research output: Contribution to journalArticle

  5. Assessment of early response biomarkers in relation to long-term survival in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy plus bevacizumab: Results from the Phase II PROMIX trial

    Siker Kimbung, Markholm, I., Bjöhle, J., Lekberg, T., Wachenfeldt, V. A., Azavedo, E., Saracco, A., Hellström, M., Srinivas Veerla, Paquet, E., Pär Ola Bendahl, Mårten Fernö, Bergh, J., Niklas Loman, Hatschek, T. & Ingrid Hedenfalk, 2018, In : International Journal of Cancer. 142, 3, p. 618-628

    Research output: Contribution to journalArticle

  6. Dynamic evaluation of the immune infiltrate and immune function genes as predictive markers for neoadjuvant chemotherapy in hormone receptor positive, HER2 negative breast cancer

    Matikas, A., Lövrot, J., Ramberg, A., Eriksson, M., Lindsten, T., Lekberg, T., Ingrid Hedenfalk, Niklas Loman, Bergh, J., Hatschek, T., Erlandsson, A. & Foukakis, T., 2018, In : OncoImmunology. 7, 9, e1466017.

    Research output: Contribution to journalArticle

  7. Ghrelin expression is associated with a favorable outcome in male breast cancer

    Grönberg, M., Nilsson, C., Markholm, I., Ingrid Hedenfalk, Blomqvist, C., Holmberg, L., Tiensuu Janson, E. & Fjällskog, M. L., 2018, In : Scientific Reports. 8, 1, 13586.

    Research output: Contribution to journalArticle

  8. 2017
  9. An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

    Palazon, A., Tyrakis, P. A., Macias, D., Veliça, P., Rundqvist, H., Fitzpatrick, S., Vojnovic, N., Phan, A. T., Niklas Loman, Ingrid Hedenfalk, Hatschek, T., Lövrot, J., Foukakis, T., Goldrath, A. W., Bergh, J. & Johnson, R. S., 2017 Nov 13, In : Cancer Cell. 32, 5, p. 669-683.e5

    Research output: Contribution to journalArticle

  10. Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: A case control study

    Lawler, K., Papouli, E., Naceur-Lombardelli, C., Mera, A., Ougham, K., Tutt, A., Siker Kimbung, Ingrid Hedenfalk, Zhan, J., Zhang, H., Buus, R., Dowsett, M., Ng, T., Pinder, S. E., Parker, P., Holmberg, L., Gillett, C. E., Grigoriadis, A. & Purushotham, A., 2017 Oct 13, In : Breast Cancer Research. 19, 1, 113.

    Research output: Contribution to journalArticle

  11. Involvement of chromatin remodeling genes and the Rho GTPases RhoB and CDC42 in ovarian clear cell carcinoma

    Nicolai Skovbjerg Arildsen, Jenny Maria Jönsson, Bartuma, K., Anna Ebbesson, Westbom-Fremer, S., Måsbäck, A., Malander, S., Mef Nilbert & Ingrid A. Hedenfalk, 2017 May 29, In : Frontiers in Oncology. 7, MAY, p. 1-11 109.

    Research output: Contribution to journalArticle

  12. A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer

    Humphries, M. P., Rajan, S. S., Droop, A., Suleman, C. A. B., Carbone, C., Nilsson, C., Honarpisheh, H., Cserni, G., Dent, J., Fulford, L., Jordan, L. B., Jones, J. L., Kanthan, R., Litwiniuk, M., Di Benedetto, A., Mottolese, M., Provenzano, E., Shousha, S., Stephens, M., Walker, R. A. & 12 othersKulka, J., Ellis, I. O., Jeffery, M., Thygesen, H. H., Cappelletti, V., Daidone, M. G., Ingrid A. Hedenfalk, Fjällskog, M-L., Melisi, D., Stead, L. F., Shaaban, A. M. & Speirs, V., 2017 May 15, In : Clinical Cancer Research. 23, 10, p. 2575-2583 9 p.

    Research output: Contribution to journalArticle

  13. 2016
  14. Transcriptional profiling of breast cancer metastases identifies liver metastasis-selective genes associated with adverse outcome in luminal A primary breast cancer.

    Siker Kimbung, Johansson, I., Danielsson, A., Srinivas Veerla, Brage, S. E., Frostvik Stolt, M., Skoog, L., Carlsson, L., Einbeigi, Z., Lidbrink, E., Linderholm, B. K., Niklas Loman, Per Malmström, Söderberg, M., Walz, T. M., Fernö, M., Hatschek, T. & Ingrid Hedenfalk, 2016, In : Clinical Cancer Research. 22, 1, p. 146-157

    Research output: Contribution to journalArticle

  15. 2015
  16. Clinical and molecular complexity of breast cancer metastases.

    Siker Kimbung, Niklas Loman & Ingrid Hedenfalk, 2015, In : Seminars in Cancer Biology. 35, p. 85-95

    Research output: Contribution to journalReview article

  17. Contrasting breast cancer molecular subtypes across serial tumor progression stages: biological and prognostic implications.

    Siker Kimbung, Kovács, A., Danielsson, A., Pär-Ola Bendahl, Lövgren, K., Stolt, M. F., Tobin, N. P., Lindström, L., Bergh, J., Einbeigi, Z., Mårten Fernö, Hatschek, T. & Ingrid Hedenfalk, 2015, In : Oncotarget. 6, 32, p. 33306-33318

    Research output: Contribution to journalArticle

  18. Sex Steroid Hormone Receptor Expression Affects Ovarian Cancer Survival.

    Jenny-Maria Jönsson, Nicolai Arildsen, Malander, S., Måsbäck, A., Linda Werner Hartman, Mef Nilbert & Ingrid Hedenfalk, 2015, In : Translational Oncology. 8, 5, p. 424-433

    Research output: Contribution to journalArticle

  19. 2014
  20. 32p * biomarkers and molecular subtypes in primary breast tumors and metastases: associations with liver metastases and outcome.

    Siker Kimbung, Kovács, A., Johansson, I., Danielsson, A., Pär-Ola Bendahl, Einbeigi, Z., Mårten Fernö, Hatschek, T. & Ingrid Hedenfalk, 2014, In : Annals of Oncology. 25 Suppl 1, May, p. i11-i12

    Research output: Contribution to journalArticle

  21. Molecular profiling of male breast cancer - Lost in translation?

    Johansson, I., Killander, F., Linderholm, B. & Ingrid Hedenfalk, 2014, In : International Journal of Biochemistry & Cell Biology. 53, May 16, p. 526-535

    Research output: Contribution to journalReview article

  22. Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

    Jenny-Maria Jönsson, Johansson, I., Dominguez, M., Siker Kimbung, Mats Jönsson, Bonde, J. H., Päivi Kannisto, Måsbäck, A., Malander, S., Mef Nilbert & Ingrid Hedenfalk, 2014, In : PLoS ONE. 9, 9, e107643.

    Research output: Contribution to journalArticle

  23. Nuclear HIF1A expression is strongly prognostic in sporadic but not familial male breast cancer.

    Deb, S., Johansson, I., Byrne, D., Nilsson, C., Investigators, K., Constable, L., Fjällskog, M-L., Dobrovic, A., Ingrid Hedenfalk & Fox, S. B., 2014, In : Modern Pathology. 27, 9, p. 1223-1230

    Research output: Contribution to journalArticle

  24. 2013
  25. Cancerforskning vid Lunds universitet: En rapport avseende forskning inom Regionalt Cancercentrum Syd

    Ingrid Hedenfalk, Graffner, M., Fredrik Åström & Mef Nilbert, 2013, Regionalt Cancercentrum Syd. 9 p.

    Research output: Book/ReportReport

  26. Effects of Research Funding, Gender and Type of Position on Research Collaboration Networks: A Micro-level Study of Cancer Research at Lund University

    Fredrik Åström, Ingrid Hedenfalk, Graffner, M. & Mef Nilbert, 2013, PROCEEDINGS OF ISSI 2013 Vienna: 14th International Society of Scientometrics and Informetrics Conference. Gorraiz, J., Schiebel, E., Gumpenberger, C., Hörlesberger, M. & Moed, H. (eds.). Austrian Institute of Technology GmbH Vienna, p. 677-689

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  27. High proliferation is associated with inferior Outcome in male breast cancer patients

    Nilsson, C., Koliadi, A., Johansson, I., Ahlin, C., Thorstenson, S., Bergkvist, L., Ingrid Hedenfalk & Fjallskog, M-L., 2013, In : Modern Pathology. 26, 1, p. 87-94

    Research output: Contribution to journalArticle

  28. Molecular subtyping of male breast cancer using alternative definitions and its prognostic impact

    Nilsson, C., Johansson, I., Ahlin, C., Thorstenson, S., Amini, R-M., Holmqvist, M., Bergkvist, L., Ingrid Hedenfalk & Fjallskog, M-L., 2013, In : Acta Oncologica. 52, 1, p. 102-109

    Research output: Contribution to journalArticle

  29. Requirement of Apoptotic Protease-Activating Factor-1 for Bortezomib-Induced Apoptosis but Not for Fas-Mediated Apoptosis in Human Leukemic Cells

    Ottosson-Wadlund, A., Ceder, R., Preta, G., Pokrovskaja, K., Grafstrom, R. C., Heyman, M., Soderhall, S., Grander, D., Ingrid Hedenfalk, Robertson, J. D. & Fadeel, B., 2013, In : Molecular Pharmacology. 83, 1, p. 245-255

    Research output: Contribution to journalArticle

  30. The Landscape of Candidate Driver Genes Differs between Male and Female Breast Cancer.

    Johansson, I., Markus Ringnér & Ingrid Hedenfalk, 2013, In : PLoS ONE. 8, 10, e78299.

    Research output: Contribution to journalArticle

  31. 2012
  32. Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition.

    Siker Kimbung, Biskup, E., Johansson, I., Kristina Aaltonen, Ottosson-Wadlund, A., Sofia Gruvberger, Cunliffe, H., Fadeel, B., Niklas Loman, Berglund, P. & Ingrid Hedenfalk, 2012, In : Cancer Letters. 319, 2, p. 232-241

    Research output: Contribution to journalArticle

  33. Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker

    Johansson, I., Nilsson, C., Berglund, P., Martin Lauss, Markus Ringnér, Håkan Olsson, Luts, L., Sim, E., Thorstensson, S., Fjallskog, M-L. & Ingrid Hedenfalk, 2012, In : Breast Cancer Research. 14, 1, R31.

    Research output: Contribution to journalArticle

  34. Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

    Orr, N., Lemnrau, A., Cooke, R., Fletcher, O., Tomczyk, K., Jones, M., Johnson, N., Lord, C. J., Mitsopoulos, C., Zvelebil, M., McDade, S. S., Buck, G., Blancher, C., Trainer, A. H., James, P. A., Bojesen, S. E., Bokmand, S., Nevanlinna, H., Mattson, J., Friedman, E. & 24 othersLaitman, Y., Palli, D., Masala, G., Zanna, I., Ottini, L., Giannini, G., Hollestelle, A., van den Ouweland, A. M. W., Novakovic, S., Krajc, M., Gago-Dominguez, M., Castelao, J. E., Håkan Olsson, Ingrid Hedenfalk, Easton, D. F., Pharoah, P. D. P., Dunning, A. M., Bishop, D. T., Neuhausen, S. L., Steele, L., Houlston, R. S., Garcia-Closas, M., Ashworth, A. & Swerdlow, A. J., 2012, In : Nature Genetics. 44, 11, p. 1182-1184

    Research output: Contribution to journalArticle

  35. 2011
  36. High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer

    Johansson, I., Nilsson, C., Berglund, P., Carina Forsare, Göran B Jönsson, Johan Staaf, Markus Ringnér, Nevanlinna, H., Barkardottir, R. B., Åke Borg, Håkan Olsson, Luts, L., Fjallskog, M-L. & Ingrid Hedenfalk, 2011, In : Breast Cancer Research and Treatment. 129, 3, p. 747-760

    Research output: Contribution to journalArticle

  37. Similarities and differences in the characteristics and primary treatment of breast cancer in men and women - a population based study (Sweden)

    Nilsson, C., Holmqvist, M., Bergkvist, L., Ingrid Hedenfalk, Lambe, M. & Fjallskog, M-L., 2011, In : Acta Oncologica. 50, 7, p. 1083-1088

    Research output: Contribution to journalArticle

  38. 2010
  39. 2008
  40. 2007
  41. 2006
  42. cDNA Microarrays in Cancer Research.

    Brown, KM., Ingrid Hedenfalk & Trent, JM., 2006, Cancer: Principles and Practise of Oncology. DeVita, VT., Hellman, S. & Rosenberg, SA. (eds.). Lippincott Williams & Wilkins, p. 13-25

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  43. Gene Expression Profiling Can Distinguish Tumor Subclasses of Breast Carcinomas.

    Ingrid Hedenfalk, 2006, Gene Expression Profiling by Microarrays – Clinical Implications.. Hofmann, W. K. (ed.). Cambridge University Press, p. 132

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  44. Microarrays in breast cancer research and clinical practice - the future lies ahead

    Sofia Gruvberger, Cunliffe, H. E., Carr, K. M. & Ingrid Hedenfalk, 2006, In : Endocrine-Related Cancer. 13, 4, p. 1017-1031

    Research output: Contribution to journalReview article

  45. 2005
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