Isabel Goncalves

ProfessorKnown as name: Isabel Gonçalves
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  1. 2019
  2. Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages

    Lunde, N. N., Gregersen, I., Ueland, T., Shetelig, C., Holm, S., Kong, X. Y., Michelsen, A. E., Otterdal, K., Yndestad, A., Broch, K., Gullestad, L., Nyman, T. A., Bendz, B., Eritsland, J., Hoffmann, P., Skagen, K., Gonçalves, I., Nilsson, J., Grenegård, M., Poreba, M. & 11 others, Drag, M., Seljeflot, I., Sporsheim, B., Espevik, T., Skjelland, M., Johansen, H. T., Solberg, R., Aukrust, P., Harry Björkbacka, Andersen, G. Ø. & Halvorsen, B., 2019 Dec 14, In : Atherosclerosis.

    Research output: Contribution to journalArticle

  3. Cardiovascular organ damage in type 2 diabetes mellitus: The role of lipids and inflammation

    Kozakova, M., Morizzo, C., Isabel Goncalves, Natali, A., Jan Nilsson & Palombo, C., 2019 May 10, In : Cardiovascular Diabetology. 18, 1, 61.

    Research output: Contribution to journalArticle

  4. Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: A nested, case–control study

    Natali, A., Nesti, L., Venturi, E., Shore, A. C., Khan, F., Gooding, K., Gates, P. E., Looker, H. C., Dove, F., Isabel Goncalves, Margaretha Persson, Jan Nilsson & The SUMMIT consortium, 2019 Feb, In : Diabetes, Obesity and Metabolism. 21, 2, p. 412-416

    Research output: Contribution to journalArticle

  5. A biomarker of collagen type I degradation is associated with cardiovascular events and mortality in patients with atherosclerosis

    Holm Nielsen, S., C. Tengryd, A. Edsfeldt, Brix, S., Genovese, F., E. Bengtsson, Karsdal, M., Leeming, D. J., J. Nilsson & I. Goncalves, 2019 Jan, In : Journal of Internal Medicine. 285, 1, p. 118-123

    Research output: Contribution to journalArticle

  6. Cartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques

    Hultman, K., Andreas Edsfeldt, Harry Björkbacka, Pontus Dunér, Sundius, L., Nitulescu, M., Persson, A., Boyle, J. J., Jan Nilsson, Anna Hultgårdh-Nilsson, Eva Bengtsson & Isabel Gonçalves, 2019, In : Stroke. 50, 11, p. 3289-3292 4 p.

    Research output: Contribution to journalArticle

  7. Soluble TRAIL-R2 a marker of plaque cell apoptosis and cardiovascular events.

    Isabel Goncalves, Singh, P., Christoffer Tengryd, Cavalera, M., Ingrid Yao Mattisson, Nitulescu, M., Persson, A., Volkov, P., Marju Orho-Melander, Gunnar Engström, Jan Nilsson & Andreas Edsfeldt, 2019, In : Stroke: a journal of cerebral circulation. 50, 8, p. 1989-1996

    Research output: Contribution to journalArticle

  8. Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy

    Saliba-Gustafsson, P., Pedrelli, M., Gertow, K., Werngren, O., Janas, V., Pourteymour, S., Baldassarre, D., Tremoli, E., Veglia, F., Rauramaa, R., Smit, A. J., Giral, P., Kurl, S., Pirro, M., de Faire, U., Humphries, S. E., Hamsten, A., Gonçalves, I., Orho-Melander, M., Franco-Cereceda, A. & 6 others, Borén, J., Eriksson, P., Magné, J., Parini, P., Ehrenborg, E. & IMPROVE Study Group, 2019, In : Journal of Internal Medicine. 286, 6, p. 660-675 16 p.

    Research output: Contribution to journalArticle

  9. Transthyretin expression in the postischemic brain

    Daniela Talhada, Isabel Gonçalves, Santos, C. R. & Karsten Ruscher, 2019, In : PLoS ONE. 14, 9, e0221555.

    Research output: Contribution to journalArticle

  10. 2018
  11. Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study

    Shore, A. C., Colhoun, H. M., Natali, A., Palombo, C., Khan, F., Östling, G., Aizawa, K., Kennbäck, C., Casanova, F., Persson, M., Gooding, K., Gates, P. E., Looker, H., Dove, F., Belch, J., Pinnola, S., Venturi, E., Kozakova, M., Goncalves, I., Kravic, J. & 3 others, Harry Björkbacka, Jan Nilsson & SUMMIT Consortium, 2018 Oct, In : Diabetes Care. 41, 10, p. 2212-2219 8 p.

    Research output: Contribution to journalArticle

  12. Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques

    Lukas Tomas, Andreas Edsfeldt, Mollet, I. G., Perisic Matic, L., Prehn, C., Adamski, J., Paulsson-Berne, G., Hedin, U., Jan Nilsson, Eva Bengtsson, Isabel Gonçalves & Harry Björkbacka, 2018 Jun 21, In : European Heart Journal. 39, 24, p. 2301-2310

    Research output: Contribution to journalArticle

  13. Markers of basement membrane remodeling are associated with higher mortality in patients with known atherosclerosis

    Nielsen, S. H., Christoffer Tengryd, Andreas Edsfeldt, Brix, S., Genovese, F., Eva Bengtsson, Karsdal, M., Leeming, D. J., Jan Nilsson & Isabel Goncalves, 2018, In : Journal of the American Heart Association. 7, 21, e009193.

    Research output: Contribution to journalArticle

  14. 2017
  15. Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis

    Gohar, A., Isabel Gonçalves, Vrijenhoek, J., Haitjema, S., van Koeverden, I., Jan Nilsson, de Borst, G. J., de Vries, J-P. P. M., Pasterkamp, G., den Ruijter, H. M., Harry Björkbacka & de Jager, S. C. A., 2017, In : International Journal of Cardiology. 241, p. 430-436

    Research output: Contribution to journalArticle

  16. Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis

    Seneviratne, A. N., Andreas Edsfeldt, Cole, J. E., Kassiteridi, C., Swart, M., Park, I., Green, P., Khoyratty, T., Saliba, D., Goddard, M. E., Sansom, S. N., Isabel Goncalves, Krams, R., Udalova, I. A. & Monaco, C., 2017, In : Circulation. 136, 5, p. 1140-1154

    Research output: Contribution to journalArticle

  17. 2016
  18. Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

    Gonçalves, I., Edsfeldt, A., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Fredrikson, G. N., Björkbacka, H., Wigren, M., Bengtsson, E., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Gates, P., Khan, F., Looker, H. C., Adams, F., Belch, J. & 6 others, Pinnola, S., Venturi, E., Kozakova, M., Gan, L. M., Schnecke, V. & Jan Nilsson, 2016 Sep 5, In : BMC Cardiovascular Disorders. 16, 1, p. 1-10 10 p., 171.

    Research output: Contribution to journalArticle

  19. Elevated CA125 is associated with incident heart failure and increased mortality in patients with acute coronary syndrome

    T. Yndigegn, Grufman, A. H. M., D. Erlinge, Nilsson, J., I. Goncalves & A. Schiopu, 2016 Aug 1, In : European Heart Journal. 37, Suppl 1, p. 1392-1393

    Research output: Contribution to journalPublished meeting abstract

  20. Decreased levels of stem cell factor in subjects with incident coronary events.

    Maria Wigren, Sara Rattik, Hultman, K., Harry Björkbacka, Nordin Fredrikson, G., Eva Bengtsson, Bo Hedblad, Siegbahn, A., Isabel Goncalves & Jan Nilsson, 2016, In : Journal of Internal Medicine. 279, 2, p. 180-191

    Research output: Contribution to journalArticle

  21. Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

    Berglund, L., Lyssenko, V., Ladenvall, C., Kotova, O., Edsfeldt, A., Pilgaard, K., Alkayyali, S., Brøns, C., Forsblom, C., Jonsson, A., Zetterqvist, A., Nitulescu, M., Ruiz McDavitt, C., Dunér, P., Stancáková, A., Kuusisto, J., Ahlqvist, E., Lajer, M., Tarnow, L., Madsbad, S. & 13 others, Rossing, P., Kieffer, T. J., Olle Melander, Marju Orho-Melander, Peter Nilsson, Groop, P-H., Allan Vaag, Lindblad, B., Anders Gottsäter, Laakso, M., Isabel Goncalves, Leif Groop & Maria Gomez, 2016, In : Diabetes. 65, 1, p. 239-254

    Research output: Contribution to journalArticle

  22. Proinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque

    Andreas Edsfeldt, Pontus Dunér, Ståhlman, M., Mollet, I. G., Giuseppe Asciutto, GRUFMAN, ANNA. HELENA. MARIA., Nitulescu, M., Persson, A. F., Fisher, R. M., Olle Melander, Marju Orho-Melander, Borén, J., Jan Nilsson & Isabel Gonçalves, 2016, In : Arteriosclerosis, Thrombosis and Vascular Biology. 36, 6, p. 1132-1140

    Research output: Contribution to journalArticle

  23. 2015
  24. Galectin 3 is a powerful risk predictor for recurrent coronary events in acute coronary syndrome patients

    A. Schiopu, T. Yndigegn, Grufman, A. H. M., Nilsson, J. & I. Goncalves, 2015 Aug 1, In : European Heart Journal. 36, Suppl 1, p. 11

    Research output: Contribution to journalPublished meeting abstract

  25. Chronic Inflammation and Atherosclerosis

    Jan Nilsson, Isabel Gonçalves & Andreas Edsfeldt, 2015 Jan 1, Early Vascular Aging (EVA): New Directions in Cardiovascular Protection. Nilsson, P. M., Olsen, M. H. & Laurent, S. (eds.). Oxford: Elsevier Science Ltd, p. 157-167 11 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  26. ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability.

    Magné, J., Gustafsson, P., Jin, H., Maegdefessel, L., Hultenby, K., Wernerson, A., Eriksson, P., Franco-Cereceda, A., Kovanen, P. T., Isabel Goncalves & Ehrenborg, E., 2015, In : Arteriosclerosis, Thrombosis and Vascular Biology. 35, 5, p. 1226-1235

    Research output: Contribution to journalArticle

  27. Atherosclerosis and general principles of arterial imaging.

    Isabel Goncalves, Nuno Dias & Peter M Nilsson, 2015, Assessment of Preclinical Organ Damage in Hypertension. Agabiti Rosei, E. & Mancia, G. (eds.). Springer, p. 81-95

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  28. Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.

    Andreas Edsfeldt, Grufman, H., Giuseppe Asciutto, Nitulescu, M., Persson, A., Nilsson, M. MN., Jan Nilsson & Isabel Goncalves, 2015, In : Atherosclerosis. 241, 2, p. 443-449

    Research output: Contribution to journalArticle

  29. Detecting the vulnerable plaque in patients.

    Isabel Goncalves, den Ruijter, H., Nahrendorf, M. & Pasterkamp, G., 2015, In : Journal of Internal Medicine. 278, 5, p. 520-530

    Research output: Contribution to journalReview article

  30. Direct association between diet and the stability of human atherosclerotic plaque.

    Isabel Goncalves, Georgiadou, E., Sören Mattsson, Skog, G., Pedro, L., Fernandes E Fernandes, J., Nuno Dias, Gunnar Engström, Jan Nilsson & Stenström, K., 2015, In : Scientific Reports. 5, 15524.

    Research output: Contribution to journalArticle

  31. DNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular Events.

    Zaina, S., Isabel Goncalves, Carmona, F. J., Gomez, A., Heyn, H., Mollet, I., Moran, S., Varol, N. & Esteller, M., 2015, In : Arteriosclerosis, Thrombosis and Vascular Biology. 35, 8, p. 1835-1842

    Research output: Contribution to journalArticle

  32. Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

    Goncalves, I., Bengtsson, E., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Edsfeldt, A., Dunér, P., Nordin Fredrikson, G., Björkbacka, H., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Strain, D., Kahn, F., Looker, H. C., Adams, F., Belch, J. & 6 others, Pinnoli, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V. & Jan Nilsson, 2015, In : Arteriosclerosis, Thrombosis and Vascular Biology. 35, 7, p. 1723-1731

    Research output: Contribution to journalArticle

  33. Imaging and Ageing of the Aorta and Large Arteries in the Lower Extremity

    Nuno Dias, Isabel Goncalves & Peter Nilsson, 2015, Assessment of Preclinical Organ Damage in Hypertension. Agabiti Rosei, E. & Mancia, G. (eds.). Springer, p. 97-114

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

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