Isabel Goncalves

ProfessorKnown as name: Isabel Gonçalves
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  1. 2021
  2. Material Decomposition in Low-Energy Micro-CT Using a Dual-Threshold Photon Counting X-Ray Detector

    Rasmus Solem, Till Dreier, Isabel Gonçalves & Martin Bech, 2021 May 10, In: Frontiers in Physics. 9, 8 p., 673843.

    Research output: Contribution to journalArticle

  3. The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis

    S. Holm Nielsen, A. Edsfeldt, C. Tengryd, H. Gustafsson, A. C. Shore, A. Natali, F. Khan, F. Genovese, E. Bengtsson, M. Karsdal, D. J. Leeming, J. Nilsson & I. Goncalves, 2021 May 5, In: Journal of Internal Medicine.

    Research output: Contribution to journalArticle

  4. Glucocorticoid induced TNF receptor family-related protein (GITR) – A novel driver of atherosclerosis

    Laura A. Bosmans, Annelie Shami, Dorothee Atzler, Christian Weber, Isabel Gonçalves & Esther Lutgens, 2021, In: Vascular Pharmacology. 139, 106884.

    Research output: Contribution to journalReview article

  5. 2020
  6. The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death

    Christoffer Tengryd, Signe Holm Nielsen, Michele Cavalera, Eva Bengtsson, Federica Genovese, Morten Karsdal, Pontus Dunér, Marju Orho-Melander, Jan Nilsson, Andreas Edsfeldt & Isabel Gonçalves, 2020 Nov, In: Atherosclerosis. 313, p. 88-95 8 p.

    Research output: Contribution to journalArticle

  7. The conundrum of asymptomatic carotid stenosis-determinants of decision and evidence

    José Fernandes E Fernandes, Luis Mendes Pedro & Isabel Gonçalves, 2020 Oct, In: Annals of Translational Medicine. 8, 19, 17 p.

    Research output: Contribution to journalReview article

  8. Exploring the role of extracellular matrix proteins to develop biomarkers of plaque vulnerability and outcome

    S. Holm Nielsen, L. Jonasson, K. Kalogeropoulos, M. A. Karsdal, A. L. Reese-Petersen, U. auf dem Keller, F. Genovese, J. Nilsson & I. Goncalves, 2020 May, In: Journal of Internal Medicine. 287, 5, p. 493-513 21 p.

    Research output: Contribution to journalReview article

  9. Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages

    Ngoc Nguyen Lunde, Ida Gregersen, Thor Ueland, Christian Shetelig, Sverre Holm, Xiang Yi Kong, Annika E. Michelsen, Kari Otterdal, Arne Yndestad, Kaspar Broch, Lars Gullestad, Tuula A. Nyman, Bjørn Bendz, Jan Eritsland, Pavel Hoffmann, Karolina Skagen, Isabel Gonçalves, Jan Nilsson, Magnus Grenegård, Marcin Poreba & 11 others, Marcin Drag, Ingebjørg Seljeflot, Bjørnar Sporsheim, Terje Espevik, Mona Skjelland, Harald Thidemann Johansen, Rigmor Solberg, Pål Aukrust, Harry Björkbacka, Geir Øystein Andersen & Bente Halvorsen, 2020 Mar 1, In: Atherosclerosis. 296, p. 74-82 9 p.

    Research output: Contribution to journalArticle

  10. CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques

    Eva Bengtsson, Karin Hultman, Andreas Edsfeldt, Ana Persson, Mihaela Nitulescu, Jan Nilsson, Isabel Gonçalves & Harry Björkbacka, 2020, In: Scientific Reports. 10, 1, 14362.

    Research output: Contribution to journalArticle

  11. Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans

    Annelie Shami, Dorothee Atzler, Laura A. Bosmans, Holger Winkels, Svenja Meiler, Michael Lacy, Claudia van Tiel, Remco Ta Megens, Katrin Nitz, Jeroen Baardman, Pascal Kusters, Tom Seijkens, Christina Buerger, Aleksandar Janjic, Carlo Riccardi, Andreas Edsfeldt, Claudia Monaco, Mat Daemen, Menno P.J. de Winther, Jan Nilsson & 4 others, Christian Weber, Norbert Gerdes, Isabel Gonçalves & Esther Lutgens, 2020, In: European Heart Journal. 41, 31, p. 2938-2948 11 p.

    Research output: Contribution to journalArticle

  12. Reduced oxidized LDL in T2D plaques is associated with a greater statin usage but not with future cardiovascular events

    Pratibha Singh, Isabel Goncalves, Christoffer Tengryd, Mihaela Nitulescu, Ana F. Persson, Fong To, Eva Bengtsson, Petr Volkov, Marju Orho-Melander, Jan Nilsson & Andreas Edsfeldt, 2020, In: Cardiovascular Diabetology. 19, 1, 214.

    Research output: Contribution to journalArticle

  13. S100A9 Links Inflammation and Repair in Myocardial Infarction

    Goran Marinković, Duco Steven Koenis, Lisa de Camp, Robert Jablonowski, Naomi Graber, Vivian de Waard, Carlie Jacoba de Vries, Isabel Goncalves, Jan Nilsson, Stefan Jovinge & Alexandru Schiopu, 2020, In: Circulation Research. 127, 5, p. 664-676 13 p.

    Research output: Contribution to journalArticle

  14. 2019
  15. Cardiovascular organ damage in type 2 diabetes mellitus: The role of lipids and inflammation

    Michaela Kozakova, Carmela Morizzo, Isabel Goncalves, Andrea Natali, Jan Nilsson & Carlo Palombo, 2019 May 10, In: Cardiovascular Diabetology. 18, 1, 61.

    Research output: Contribution to journalArticle

  16. Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: A nested, case–control study

    Andrea Natali, Lorenzo Nesti, Elena Venturi, Angela C. Shore, Faisel Khan, Kim Gooding, Phillip E. Gates, Helen C. Looker, Fiona Dove, Isabel Goncalves, Margaretha Persson, Jan Nilsson & The SUMMIT consortium The SUMMIT consortium, 2019 Feb, In: Diabetes, Obesity and Metabolism. 21, 2, p. 412-416

    Research output: Contribution to journalArticle

  17. A biomarker of collagen type I degradation is associated with cardiovascular events and mortality in patients with atherosclerosis

    S. Holm Nielsen, C. Tengryd, A. Edsfeldt, S. Brix, F. Genovese, E. Bengtsson, M. Karsdal, D. J. Leeming, J. Nilsson & I. Goncalves, 2019 Jan, In: Journal of Internal Medicine. 285, 1, p. 118-123

    Research output: Contribution to journalArticle

  18. Cartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques

    Karin Hultman, Andreas Edsfeldt, Harry Björkbacka, Pontus Dunér, Lena Sundius, Mihaela Nitulescu, Ana Persson, Joseph J Boyle, Jan Nilsson, Anna Hultgårdh-Nilsson, Eva Bengtsson & Isabel Gonçalves, 2019, In: Stroke. 50, 11, p. 3289-3292 4 p.

    Research output: Contribution to journalArticle

  19. Inhibition of pro-inflammatory myeloid cell responses by short-term S100A9 blockade improves cardiac function after myocardial infarction

    Goran Marinković, Helena Grauen Larsen, Troels Yndigegn, Istvan Adorjan Szabo, Razvan Gheorghita Mares, Lisa de Camp, Matthew Weiland, Lukas Tomas, Isabel Goncalves, Jan Nilsson, Stefan Jovinge & Alexandru Schiopu, 2019, In: European Heart Journal. 40, 32, p. 2713-2723 11 p.

    Research output: Contribution to journalArticle

  20. Soluble TRAIL-R2 a marker of plaque cell apoptosis and cardiovascular events.

    Isabel Goncalves, Pratibha Singh, Christoffer Tengryd, Michele Cavalera, Ingrid Yao Mattisson, Mihaela Nitulescu, Ana Persson, Petr Volkov, Marju Orho-Melander, Gunnar Engström, Jan Nilsson & Andreas Edsfeldt, 2019, In: Stroke: a journal of cerebral circulation. 50, 8, p. 1989-1996

    Research output: Contribution to journalArticle

  21. Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy

    P. Saliba-Gustafsson, M. Pedrelli, K. Gertow, O. Werngren, V. Janas, S. Pourteymour, D. Baldassarre, E. Tremoli, F. Veglia, R. Rauramaa, A. J. Smit, P. Giral, S. Kurl, M. Pirro, U. de Faire, S. E. Humphries, A. Hamsten, I. Gonçalves, M. Orho-Melander, A. Franco-Cereceda & 6 others, J. Borén, P. Eriksson, J. Magné, P. Parini, E. Ehrenborg & IMPROVE Study Group IMPROVE Study Group, 2019, In: Journal of Internal Medicine. 286, 6, p. 660-675 16 p.

    Research output: Contribution to journalArticle

  22. Transthyretin expression in the postischemic brain

    Daniela Talhada, Isabel Gonçalves, Cecília Reis Santos & Karsten Ruscher, 2019, In: PLoS ONE. 14, 9, e0221555.

    Research output: Contribution to journalArticle

  23. 2018
  24. Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study

    Angela C Shore, Helen M Colhoun, Andrea Natali, Carlo Palombo, Faisel Khan, Gerd Östling, Kunihiko Aizawa, Cecilia Kennbäck, Francesco Casanova, Margaretha Persson, Kim Gooding, Phillip E Gates, Helen Looker, Fiona Dove, Jill Belch, Silvia Pinnola, Elena Venturi, Michaela Kozakova, Isabel Goncalves, Jasmina Kravic & 3 others, Harry Björkbacka, Jan Nilsson & SUMMIT Consortium SUMMIT Consortium, 2018 Oct, In: Diabetes Care. 41, 10, p. 2212-2219 8 p.

    Research output: Contribution to journalArticle

  25. Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques

    Lukas Tomas, Andreas Edsfeldt, Inês G Mollet, Ljubica Perisic Matic, Cornelia Prehn, Jerzy Adamski, Gabrielle Paulsson-Berne, Ulf Hedin, Jan Nilsson, Eva Bengtsson, Isabel Gonçalves & Harry Björkbacka, 2018 Jun 21, In: European Heart Journal. 39, 24, p. 2301-2310

    Research output: Contribution to journalArticle

  26. Markers of basement membrane remodeling are associated with higher mortality in patients with known atherosclerosis

    Signe Holm Nielsen, Christoffer Tengryd, Andreas Edsfeldt, Susanne Brix, Federica Genovese, Eva Bengtsson, Morten Karsdal, Diana J. Leeming, Jan Nilsson & Isabel Goncalves, 2018, In: Journal of the American Heart Association. 7, 21, e009193.

    Research output: Contribution to journalArticle

  27. Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms

    Sanela Halak, Gerd Östling, Andreas Edsfeldt, Cecilia Kennbäck, Magnus Dencker, Isabel Gonçalves & Giuseppe Asciutto, 2018, In: Cerebrovascular Diseases Extra. 8, 1, p. 16-25

    Research output: Contribution to journalArticle

  28. 2017
  29. Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis

    Aisha Gohar, Isabel Gonçalves, Joyce Vrijenhoek, Saskia Haitjema, Ian van Koeverden, Jan Nilsson, Gert J. de Borst, Jean-Paul P. M. de Vries, Gerard Pasterkamp, Hester M den Ruijter, Harry Björkbacka & Saskia C A de Jager, 2017, In: International Journal of Cardiology. 241, p. 430-436

    Research output: Contribution to journalArticle

  30. Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis

    Anusha N. Seneviratne, Andreas Edsfeldt, Jennifer E. Cole, Christina Kassiteridi, Maarten Swart, Inhye Park, Patricia Green, Tariq Khoyratty, David Saliba, Michael E Goddard, Stephen N. Sansom, Isabel Goncalves, Rob Krams, Irina A. Udalova & Claudia Monaco, 2017, In: Circulation. 136, 5, p. 1140-1154

    Research output: Contribution to journalArticle

  31. 2016
  32. Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

    Isabel Gonçalves, Andreas Edsfeldt, Helen M. Colhoun, Angela C. Shore, Carlo Palombo, Andrea Natali, Gunilla Nordin Fredrikson, Harry Björkbacka, Maria Wigren, Eva Bengtsson, Gerd Östling, Kunihiko Aizawa, Francesco Casanova, Margaretha Persson, Kim Gooding, Phil Gates, Faisel Khan, Helen C. Looker, Fiona Adams, Jill Belch & 6 others, Silvia Pinnola, Elena Venturi, Michaela Kozakova, Li Ming Gan, Volker Schnecke & Jan Nilsson, 2016 Sep 5, In: BMC Cardiovascular Disorders. 16, 1, p. 1-10 10 p., 171.

    Research output: Contribution to journalArticle

  33. Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up

    Caitríona Grönberg, Giuseppe Asciutto, Ana Persson, Gunilla Nordin Fredrikson, Jan Nilsson, Isabel Gonçalves & Harry Björkbacka, 2016 Sep, In: Cytokine. 85, p. 137-139 3 p.

    Research output: Contribution to journalArticle

  34. Elevated CA125 is associated with incident heart failure and increased mortality in patients with acute coronary syndrome

    T. Yndigegn, Anna Helena Maria Grufman, D. Erlinge, J Nilsson, I. Goncalves & A. Schiopu, 2016 Aug 1, In: European Heart Journal. 37, Suppl 1, p. 1392-1393

    Research output: Contribution to journalPublished meeting abstract

  35. Decreased levels of stem cell factor in subjects with incident coronary events.

    Maria Wigren, Sara Rattik, Karin Hultman, Harry Björkbacka, Gunilla Nordin Fredrikson, Eva Bengtsson, Bo Hedblad, A Siegbahn, Isabel Goncalves & Jan Nilsson, 2016, In: Journal of Internal Medicine. 279, 2, p. 180-191

    Research output: Contribution to journalArticle

  36. Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

    Lisa Berglund, Valeriya Lyssenko, Claes Ladenvall, Olga Kotova, Andreas Edsfeldt, Kasper Pilgaard, Sami Alkayyali, Charlotte Brøns, Carol Forsblom, Anna Jonsson, Anna Zetterqvist, Mihaela Nitulescu, Christian Ruiz McDavitt, Pontus Dunér, Alena Stancáková, Johanna Kuusisto, Emma Ahlqvist, Maria Lajer, Lise Tarnow, Sten Madsbad & 13 others, Peter Rossing, Timothy J Kieffer, Olle Melander, Marju Orho-Melander, Peter Nilsson, Per-Henrik Groop, Allan Vaag, Bengt Lindblad, Anders Gottsäter, Markku Laakso, Isabel Goncalves, Leif Groop & Maria Gomez, 2016, In: Diabetes. 65, 1, p. 239-254

    Research output: Contribution to journalArticle

  37. High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

    Isabel Goncalves, Karin Hultman, Pontus Dunér, Andreas Edsfeldt, Bo Hedblad, Gunilla Nordin Fredrikson, Harry Björkbacka, Jan Nilsson & Eva Bengtsson, 2016, In: Open Heart. 3, 1, p. e000353

    Research output: Contribution to journalArticle

  38. Proinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque

    Andreas Edsfeldt, Pontus Dunér, Marcus Ståhlman, Ines G Mollet, Giuseppe Asciutto, ANNA HELENA MARIA GRUFMAN, Mihaela Nitulescu, Ana Flor Persson, Rachel M Fisher, Olle Melander, Marju Orho-Melander, Jan Borén, Jan Nilsson & Isabel Gonçalves, 2016, In: Arteriosclerosis, Thrombosis and Vascular Biology. 36, 6, p. 1132-1140

    Research output: Contribution to journalArticle

  39. 2015
  40. Galectin 3 is a powerful risk predictor for recurrent coronary events in acute coronary syndrome patients

    A. Schiopu, T. Yndigegn, Anna Helena Maria Grufman, J. Nilsson & I. Goncalves, 2015 Aug 1, In: European Heart Journal. 36, Suppl 1, p. 11

    Research output: Contribution to journalPublished meeting abstract

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